VALKEM OD 125MG TABLET 10'S

How VALKEM OD 125MG TABLET 10'S Works

• VALKEM OD 125MG TABLET 10'S contains Valproic Acid, a medication primarily used to manage epilepsy, bipolar disorder, and prevent migraine headaches. Its mechanism of action is multifaceted, involving several key processes within the brain. Valproic Acid works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that inhibits nerve impulses, effectively calming the brain and reducing the likelihood of seizures or mood swings.
• Specifically, Valproic Acid enhances GABA levels through multiple pathways. First, it inhibits enzymes that break down GABA, such as GABA transaminase, leading to a higher concentration of GABA available in the synaptic cleft. Second, it may stimulate the synthesis of GABA, further increasing its production within nerve cells. Third, Valproic Acid might also act directly on GABA receptors, enhancing their responsiveness to GABA and amplifying its inhibitory effects.
• In the context of epilepsy, the increased GABA activity helps to stabilize neuronal excitability, preventing the excessive and uncontrolled electrical activity that characterizes seizures. By reducing neuronal firing, Valproic Acid effectively raises the seizure threshold, making it less likely for seizures to occur. For bipolar disorder, the mood-stabilizing effects of Valproic Acid are believed to be related to its influence on GABAergic neurotransmission, as well as its effects on other neurotransmitter systems like glutamate and dopamine. By modulating these neurotransmitter systems, Valproic Acid helps to reduce the severity and frequency of mood episodes.
• Furthermore, Valproic Acid's effectiveness in migraine prevention is thought to stem from its ability to reduce neuronal hyperexcitability and stabilize brain activity. Migraines are often associated with abnormal neuronal firing patterns, and Valproic Acid's calming effect on the brain can help to prevent these patterns from developing, thereby reducing the frequency and intensity of migraine headaches. The 'OD' in VALKEM OD 125MG TABLET 10'S stands for 'Once Daily', indicating that it is an extended-release formulation designed to release the medication slowly over time. This helps to maintain a consistent level of Valproic Acid in the bloodstream throughout the day, improving its effectiveness and reducing the risk of side effects associated with fluctuating drug levels.

Common side effects of VALKEM OD 125MG TABLET may include nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, headache, dizziness, drowsiness, weakness, fatigue, skin rash, itching, hair loss, and changes in liver function tests. Less common but potentially serious side effects can include liver damage, pancreatitis, and allergic reactions (such as swelling of the face, lips, tongue, or throat, difficulty breathing, and hives). Other rare side effects may include changes in blood cell counts and neurological problems. It's important to consult your doctor if you experience any unusual or persistent symptoms while taking this medication.

• If you miss a dose of VALKEM OD 125MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep VALKEM OD 125MG TAB 1X10 away from the reach of children and pets.
• Store VALKEM OD 125MG TAB 1X10 at room temperature.

• Take VALKEM OD 125MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking it without consulting your physician, even if you feel better. Consistency is key for optimal results.
• VALKEM OD is often prescribed to manage epilepsy. It's crucial to maintain a regular dosing schedule to keep seizures under control. Missing doses can increase the risk of seizure activity.
• Be aware of potential side effects. Common side effects may include nausea, vomiting, drowsiness, dizziness, or changes in appetite. If these side effects persist or worsen, inform your doctor immediately. More serious side effects require urgent medical attention.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking. VALKEM OD can interact with other drugs, potentially affecting its efficacy or increasing the risk of adverse effects. This includes over-the-counter medications.
• Avoid alcohol consumption while taking VALKEM OD, as it can exacerbate side effects such as drowsiness and dizziness. Alcohol can also interfere with the effectiveness of the medication and potentially increase the risk of seizures. Also, discuss any planned pregnancies with your doctor, as VALKEM OD might impact the fetus.
• Store VALKEM OD at room temperature, away from direct sunlight, heat, and moisture. Keep the medication out of reach of children and pets. Proper storage ensures the medication remains effective and safe to use. Do not store it in the bathroom.
• It's essential to have regular check-ups with your doctor while taking VALKEM OD. These appointments allow your doctor to monitor your progress, assess for any side effects, and adjust your dosage if needed. Blood tests may be required to monitor liver function and drug levels.

• VALKEM OD 125MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels of the medicine. Consult your doctor for specific dietary advice.