DORTIM EYE DROPS 5 ML

How DORTIM EYE DROPS 5 ML Works

• DORTIM EYE DROPS 5 ML is a combination medication designed to lower elevated intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. It contains two active ingredients: dorzolamide and timolol, each working through distinct mechanisms to achieve this pressure reduction.
• Dorzolamide is a carbonic anhydrase inhibitor. Carbonic anhydrase is an enzyme present in the eye that plays a crucial role in the production of aqueous humor, the fluid that fills the space between the cornea and the lens. By inhibiting carbonic anhydrase, dorzolamide reduces the formation of aqueous humor. This decreased production directly lowers the IOP.
• Timolol, on the other hand, is a non-selective beta-adrenergic receptor blocker. Beta-adrenergic receptors are found in various tissues of the body, including the eye. Timolol works by blocking these receptors in the ciliary body, the structure responsible for producing aqueous humor. Blocking these receptors reduces aqueous humor production, contributing to a lower IOP.
• The combination of dorzolamide and timolol provides a synergistic effect, meaning that the IOP reduction achieved by using both medications together is greater than the sum of the reductions achieved by using either medication alone. This enhanced effect is particularly beneficial for individuals who require more significant IOP lowering to prevent optic nerve damage and vision loss associated with glaucoma.
• When DORTIM EYE DROPS are instilled into the eye, both dorzolamide and timolol are absorbed into the systemic circulation. However, the amount absorbed is generally low, minimizing the risk of systemic side effects. The IOP-lowering effect typically begins within a few hours of administration and can last for up to 12 hours, allowing for twice-daily dosing. Regular use as prescribed by an ophthalmologist is crucial for maintaining consistent IOP control and protecting vision.
• In summary, DORTIM EYE DROPS 5 ML effectively lowers intraocular pressure by reducing the production of aqueous humor through two complementary mechanisms: carbonic anhydrase inhibition by dorzolamide and beta-adrenergic receptor blockade by timolol. This dual action provides a powerful and sustained IOP-lowering effect, helping to manage glaucoma and ocular hypertension.

Like all medicines, DORTIM EYE DROPS 5 ML can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Eye-related: Burning and stinging, blurred vision, itching, tearing, redness. * General: Taste alterations. **Uncommon Side Effects (may affect up to 1 in 100 people):** * Eye-related: Inflammation of the iris, eyelid inflammation. * General: Slow heartbeat, shortness of breath. **Rare Side Effects (may affect up to 1 in 1,000 people):** * Eye-related: Eye pain, crusting of the eyelids, decreased corneal sensitivity, double vision, drooping eyelids, detachment of the layer below the retina that contains blood vessels following filtration surgery which may cause visual disturbances, foreign body sensation in eye. * General: Headache, dizziness, anxiety, muscle weakness, chest pain, palpitations, insomnia, nightmares, memory loss, systemic allergic reactions including angioedema, urticaria, localized and generalized rash, pruritus, anaphylactic reaction, worsening of myasthenia gravis, cough, indigestion, dry mouth, hair loss, psoriasis-like rash or exacerbation of psoriasis, tingling or numbness of the hands and feet. **Other Possible Side Effects (frequency not known):** * Eye-related: Excessive tearing, corneal damage. * General: Decreased blood pressure, depression.

• If you miss a dose of Dortim Eye Drops, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

• Keep DORTIM EYE DROPS 5ML away from the reach of children and pets.
• Store DORTIM EYE DROPS 5ML at room temperature.

• **Understand Your Prescription:** DORTIM eye drops are prescribed to lower the pressure inside your eye (intraocular pressure), which is often associated with conditions like glaucoma or ocular hypertension. Always use it exactly as your doctor directs. Do not alter the dosage or frequency without consulting them, as this could impact the effectiveness of the medication and your overall eye health.
• **Proper Instillation Technique:** Wash your hands thoroughly before using DORTIM eye drops. Tilt your head back slightly and gently pull down your lower eyelid to create a small pocket. Hold the dropper above your eye without touching it to avoid contamination. Squeeze one drop into the pocket and gently close your eye for 1-2 minutes. Avoid blinking or squeezing your eyelids tightly, as this can push the medication out.
• **Consistency is Key:** For DORTIM eye drops to work effectively, use them consistently at the same time(s) each day as prescribed. Setting a reminder on your phone or linking it to a daily routine (like brushing your teeth) can help you remember. Missed doses can lead to fluctuations in your eye pressure and potentially affect your vision in the long run.
• **Be Aware of Potential Side Effects:** While DORTIM eye drops are generally safe, some people may experience side effects such as burning, stinging, or blurred vision immediately after instillation. These effects are usually temporary. However, if you experience more severe side effects like eye pain, redness, swelling, or vision changes, contact your doctor immediately. DORTIM eye drops can sometimes interact with other medications, so it's important to inform your doctor of all the medications you're currently taking.
• **Storage Matters:** Store your DORTIM eye drops at room temperature, away from direct sunlight and heat. Keep the bottle tightly closed when not in use and ensure the dropper tip does not come into contact with any surfaces. Do not use the eye drops if the solution changes color or contains particles. Also, do not use the eye drops if the bottle’s seal is broken. If you use contact lenses, remove them before instilling DORTIM and wait at least 15 minutes before reinserting them.

• DORTIM EYE DROPS 5 ML is administered topically, so it is unlikely to be affected by food. There are no known food interactions with DORTIM EYE DROPS 5 ML. It is recommended to follow your doctor's instructions regarding diet and other medications while using this medicine.