ENTACOM PLUS 100MG TABLET 10'S
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ENTACOM PLUS 100MG TABLET 10'S
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ENTACOM PLUS 100MG TABLET 10'S

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ENTACOM PLUS 100MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

137.5

₹116.88

15 % OFF

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10

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Product DetailsArrow

About ENTACOM PLUS 100MG TABLET 10'S

  • ENTACOM PLUS 100MG TABLET 10'S is a medication primarily used in the management of Parkinson's disease, a progressive neurological disorder that affects movement. This tablet combines multiple active ingredients to help control symptoms such as tremors, stiffness, and slowness of movement, significantly improving the quality of life for individuals living with Parkinson's.
  • The key components of ENTACOM PLUS include Levodopa, Carbidopa, and Entacapone. Levodopa is a precursor to dopamine, a neurotransmitter deficient in Parkinson's disease. It helps replenish dopamine levels in the brain, alleviating motor symptoms. Carbidopa inhibits the breakdown of Levodopa in the bloodstream, ensuring that a larger amount reaches the brain where it's needed. Entacapone further enhances the effect of Levodopa by blocking an enzyme that breaks down dopamine, thereby prolonging Levodopa's action and providing more consistent symptom control.
  • ENTACOM PLUS is typically prescribed as part of a comprehensive treatment plan. The dosage and frequency of administration are determined by a healthcare professional based on individual needs and response to the medication. It's crucial to adhere to the prescribed regimen and consult with the doctor for any adjustments. Patients should be aware of potential side effects, which may include nausea, dizziness, involuntary movements (dyskinesias), and changes in blood pressure. Regular monitoring and communication with the healthcare provider are essential for managing Parkinson's disease effectively with ENTACOM PLUS.
  • This medication aims to provide a smoother and more sustained relief from Parkinson's symptoms compared to Levodopa alone, reducing 'off' periods when symptoms re-emerge between doses. It's important to note that ENTACOM PLUS does not cure Parkinson's disease but helps manage its symptoms, allowing patients to maintain a more active and fulfilling life.

Uses of ENTACOM PLUS 100MG TABLET 10'S

  • Management of symptoms of Parkinson's disease
  • Treatment of end-of-dose motor fluctuations (wearing-off)
  • Used in combination with Levodopa
  • Improvement of motor performance
  • Reducing stiffness
  • Reducing slowness of movement (bradykinesia)
  • Control of tremors

How ENTACOM PLUS 100MG TABLET 10'S Works

  • ENTACOM PLUS 100MG TABLET 10'S is a combination medicine primarily used in the treatment of Parkinson's disease. Parkinson's disease is a progressive disorder of the nervous system that affects movement. The medication contains a combination of Levodopa, Carbidopa, and Entacapone. Each component plays a crucial role in alleviating the symptoms associated with the condition.
  • Levodopa is a precursor to dopamine, a neurotransmitter that is deficient in individuals with Parkinson's disease. By converting into dopamine in the brain, Levodopa helps to replenish the depleted levels of this essential neurotransmitter. This leads to improved motor control, reduced tremors, and enhanced muscle stiffness.
  • Carbidopa acts as a DOPA decarboxylase inhibitor. It prevents the breakdown of Levodopa in the bloodstream before it reaches the brain. This ensures that a higher proportion of Levodopa crosses the blood-brain barrier, maximizing its effectiveness in the central nervous system. Carbidopa essentially boosts the amount of Levodopa available to the brain, leading to a more significant therapeutic effect.
  • Entacapone is a selective and reversible catechol-O-methyltransferase (COMT) inhibitor. COMT is an enzyme that breaks down dopamine in the body. By inhibiting COMT, Entacapone helps to prolong the action of Levodopa by preventing the degradation of dopamine, both formed from Levodopa and naturally occurring. This leads to a more stable and sustained dopamine level in the brain, providing more consistent symptom control.
  • In summary, ENTACOM PLUS 100MG TABLET 10'S works synergistically through its three components. Levodopa increases dopamine levels in the brain, Carbidopa prevents the breakdown of Levodopa in the periphery, and Entacapone inhibits the breakdown of dopamine. This combination helps to improve motor function, reduce tremors, and alleviate muscle stiffness associated with Parkinson's disease. It's important to use this medication under the guidance of a healthcare professional, who will determine the appropriate dosage and monitor for any potential side effects.

Side Effects of ENTACOM PLUS 100MG TABLET 10'SArrow

ENTACOM PLUS 100MG TABLET 10'S can cause a range of side effects, although not everyone experiences them. Common side effects include: * Nausea * Dizziness * Dyskinesia (uncontrolled movements) * Hallucinations * Confusion * Dry mouth * Orthostatic hypotension (drop in blood pressure upon standing) * Sleep disturbances (insomnia, nightmares) * Abdominal pain * Diarrhea * Constipation * Urine discoloration (reddish-brown) * Increased sweating Less common or rare side effects may include: * Vomiting * Anorexia * Weight changes * Agitation * Anxiety * Depression * Psychosis * Impulse control disorders (e.g., compulsive gambling, hypersexuality) * Melanoma (skin cancer) * Neuroleptic malignant syndrome (NMS) - a severe reaction with fever, muscle rigidity, altered mental status, and autonomic dysfunction * Rhabdomyolysis (muscle breakdown) * Liver problems (elevated liver enzymes) * Allergic reactions (rash, itching, swelling) This is not an exhaustive list. It is important to consult your doctor if you experience any unusual or severe side effects while taking ENTACOM PLUS 100MG TABLET 10'S.

Safety Advice for ENTACOM PLUS 100MG TABLET 10'SArrow

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Allergies

Allergies

Caution: Do not use ENTACOM PLUS 100MG TABLET 10'S if you are allergic to it.

Dosage of ENTACOM PLUS 100MG TABLET 10'SArrow

  • The recommended dosage of ENTACOM PLUS 100MG TABLET 10'S varies significantly depending on individual patient needs, the severity of Parkinson's disease symptoms, and the patient's response to treatment. It's crucial to adhere strictly to your physician's instructions regarding dosage and administration. Typically, ENTACOM PLUS is administered orally, and the dosage is carefully titrated to achieve optimal symptom control while minimizing potential side effects.
  • Initial dosages often start low and are gradually increased under medical supervision. This titration process allows your doctor to carefully assess your response to the medication and adjust the dosage accordingly. The goal is to find the lowest effective dose that provides adequate symptom relief. The frequency of administration also varies, but it's commonly taken multiple times per day.
  • Factors influencing dosage adjustments include the presence of other medical conditions, concurrent medications, and individual variations in metabolism. Elderly patients may require lower doses. It's essential to inform your doctor about all medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.
  • If you miss a dose of ENTACOM PLUS 100MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Sudden discontinuation of ENTACOM PLUS can lead to withdrawal symptoms, so it should only be stopped under the guidance of your doctor.
  • Regular monitoring by your physician is necessary to assess the effectiveness of ENTACOM PLUS and to manage any potential side effects. This may involve periodic check-ups and laboratory tests. Report any unusual or bothersome symptoms to your doctor promptly. Take 'ENTACOM PLUS 100MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of ENTACOM PLUS 100MG TABLET 10'S?Arrow

  • If you miss a dose of Entacom Plus 100mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store ENTACOM PLUS 100MG TABLET 10'S?Arrow

  • Keep ENTACOM PLUS 100MG TAB 1X10 away from the reach of children and pets.
  • Store ENTACOM PLUS 100MG TAB 1X10 at room temperature.

Benefits of ENTACOM PLUS 100MG TABLET 10'SArrow

  • ENTACOM PLUS 100MG TABLET 10'S is a valuable medication primarily used in the management of Parkinson's disease, a progressive neurological disorder that affects movement. Its benefits stem from its unique composition, which combines levodopa, carbidopa, and entacapone to address the complexities of dopamine deficiency in the brain. Levodopa is a precursor to dopamine, the neurotransmitter critically lacking in Parkinson's patients. By converting into dopamine in the brain, levodopa helps to replenish dopamine levels, thereby alleviating motor symptoms such as tremors, rigidity, slow movement (bradykinesia), and postural instability.
  • Carbidopa plays a crucial role by inhibiting the breakdown of levodopa in the bloodstream before it reaches the brain. This ensures that a larger proportion of levodopa crosses the blood-brain barrier, maximizing its effectiveness and reducing the required dosage. By preventing peripheral metabolism of levodopa, carbidopa also helps minimize side effects like nausea and vomiting, which can otherwise limit levodopa's tolerability.
  • Entacapone further enhances levodopa's efficacy by blocking the COMT (catechol-O-methyltransferase) enzyme, which also breaks down levodopa in the body. By inhibiting COMT, entacapone prolongs the duration of levodopa's action in the brain, leading to more stable dopamine levels and smoother motor control throughout the day. This can translate to fewer 'off' periods, where Parkinson's symptoms return between doses, and more predictable responses to medication.
  • The combined action of these three ingredients results in significant improvements in motor function, allowing patients to perform daily activities with greater ease and independence. ENTACOM PLUS 100MG TABLET 10'S can reduce the severity of tremors, alleviate muscle stiffness, improve walking speed and balance, and enhance overall coordination. This comprehensive approach to managing dopamine deficiency makes it a cornerstone in Parkinson's disease treatment, improving patients' quality of life and functional abilities.
  • Furthermore, consistent use of ENTACOM PLUS 100MG TABLET 10'S, as prescribed by a physician, can help maintain a stable therapeutic response over time. This stability is crucial in managing the fluctuating symptoms of Parkinson's disease and preventing the development of motor complications like dyskinesias (involuntary movements). The extended-release formulation ensures a steady release of medication, minimizing peaks and troughs in dopamine levels, and providing more consistent symptom control throughout the day.
  • ENTACOM PLUS 100MG TABLET 10'S helps in improving motor skills, reducing stiffness, improving balance, and improving coordination. This in turn allows the patient to improve their daily activity and independence.
  • ENTACOM PLUS 100MG Tablet also reduces the rate of wear off time by stablizing the dopamine level in body.

How to use ENTACOM PLUS 100MG TABLET 10'SArrow

  • ENTACOM PLUS 100MG TABLET 10'S is a medication primarily used to manage the symptoms of Parkinson's disease. It's a combination medicine containing levodopa, carbidopa, and entacapone. Levodopa converts into dopamine in the brain, helping to replenish depleted dopamine levels in Parkinson's patients. Carbidopa prevents levodopa from breaking down in the bloodstream, allowing more of it to reach the brain. Entacapone prolongs the effect of levodopa by blocking an enzyme that breaks it down.
  • Always take ENTACOM PLUS 100MG TABLET 10'S exactly as your doctor prescribes. The dosage and frequency will depend on your individual condition and response to treatment. It is usually taken orally, with or without food, but consistency is key. Taking it at the same times each day helps maintain a steady level of medication in your system.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it, as this can affect how the medication is absorbed. If you have difficulty swallowing pills, discuss it with your doctor or pharmacist, as they may be able to offer alternative formulations or strategies.
  • Avoid taking ENTACOM PLUS 100MG TABLET 10'S with high-protein meals, as protein can interfere with the absorption of levodopa. It's best to take it at least 30 minutes before or one hour after eating a protein-rich meal. Be consistent with your dietary habits to ensure consistent medication absorption.
  • Do not stop taking ENTACOM PLUS 100MG TABLET 10'S suddenly, as this can lead to withdrawal symptoms or a worsening of your Parkinson's symptoms. If you need to stop taking the medication, your doctor will gradually reduce the dosage over time. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Be aware of potential side effects, which can include nausea, dizziness, lightheadedness, dyskinesias (involuntary movements), and changes in blood pressure. If you experience any troublesome or persistent side effects, inform your doctor. It's also crucial to tell your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they can interact with ENTACOM PLUS 100MG TABLET 10'S.
  • Keep ENTACOM PLUS 100MG TABLET 10'S stored at room temperature, away from heat, light, and moisture. Keep it out of reach of children and pets. Always consult your doctor or pharmacist if you have any questions or concerns about taking this medication.

Quick Tips for ENTACOM PLUS 100MG TABLET 10'SArrow

  • Take ENTACOM PLUS 100MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting your physician, as this can affect the management of your Parkinson's disease symptoms. Consistency is key for optimal results.
  • ENTACON PLUS contains levodopa, carbidopa, and entacapone. Levodopa is converted to dopamine in the brain, helping to replenish dopamine levels. Carbidopa prevents levodopa from being broken down in the bloodstream, allowing more of it to reach the brain. Entacapone prolongs the effect of levodopa by blocking an enzyme that breaks down dopamine.
  • Be aware of potential side effects, which may include nausea, dyskinesias (involuntary movements), dizziness, and orthostatic hypotension (a drop in blood pressure upon standing). If you experience any troublesome side effects, consult your doctor promptly. They may adjust your dosage or provide recommendations to manage these effects. Monitor your blood pressure regularly, especially when starting this medication or after dosage adjustments.
  • Take ENTACOM PLUS on an empty stomach, ideally 30 minutes before or 1-2 hours after meals, as food can interfere with its absorption. However, if you experience nausea, taking it with a small, non-protein snack may help. Avoid high-protein meals close to your medication dose, as they can reduce its effectiveness.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, especially those for blood pressure, mental health, or iron supplements. Drug interactions can affect how ENTACOM PLUS works or increase the risk of side effects. Iron supplements should be taken at least two hours before or after taking ENTACOM PLUS.
  • Parkinson's disease symptoms can fluctuate, and ENTACOM PLUS is designed to help manage these fluctuations. Keep a symptom diary to track how well the medication is working and any changes in your condition. Share this information with your doctor during your appointments. This will help them fine-tune your treatment plan.
  • Store ENTACOM PLUS 100MG TABLET 10'S at room temperature, away from moisture and direct sunlight. Keep it out of reach of children. If you have any unused medication, dispose of it properly according to local regulations.

Food Interactions with ENTACOM PLUS 100MG TABLET 10'SArrow

  • ENTACOM PLUS 100MG TABLET 10'S can be taken with or without food. However, taking it consistently with or without food helps maintain stable blood levels of the medication.

FAQs

What is Entacom Plus 100mg Tablet used for?Arrow

Entacom Plus 100mg Tablet is used in the treatment of Parkinson's disease. This medication helps to reduce the symptoms of Parkinson's disease, such as tremors, muscle stiffness, and difficulty in movement.

How does Entacom Plus 100mg Tablet work?Arrow

Entacom Plus 100mg Tablet works by increasing the level of dopamine in the brain. Dopamine is a chemical messenger that helps control body movements. In Parkinson's disease, the level of dopamine in the brain decreases, leading to movement difficulties.

What are the common side effects of Entacom Plus 100mg Tablet?Arrow

The common side effects of Entacom Plus 100mg Tablet include nausea, vomiting, dizziness, headache, and constipation. Inform your doctor if these side effects persist or become severe.

Can Entacom Plus 100mg Tablet be taken with or without food?Arrow

Entacom Plus 100mg Tablet can be taken with or without food, but it is best to take it at the same time each day. Follow your doctor's instructions.

Can Entacom Plus 100mg Tablet interact with other medications?Arrow

Entacom Plus 100mg Tablet can interact with certain other medications. Tell your doctor about all the medicines you are taking, including over-the-counter drugs and herbal supplements.

What to do if a dose of Entacom Plus 100mg Tablet is missed?Arrow

If you miss a dose of Entacom Plus 100mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Should Entacom Plus 100mg Tablet be stopped suddenly?Arrow

Entacom Plus 100mg Tablet should not be stopped suddenly. This can worsen symptoms. Consult your doctor before stopping the medication, as the dosage may need to be gradually reduced.

How to store Entacom Plus 100mg Tablet?Arrow

Store Entacom Plus 100mg Tablet at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

What are the symptoms of an overdose of Entacom Plus 100mg Tablet?Arrow

Symptoms of an overdose of Entacom Plus 100mg Tablet may include confusion, hallucinations, involuntary movements, and changes in heart rate. Seek immediate medical attention if you think you have overdosed on this medication.

Is Entacom Plus 100mg Tablet safe during pregnancy?Arrow

Entacom Plus 100mg Tablet should only be used during pregnancy if clearly needed and prescribed by a doctor. Discuss the risks and benefits with your doctor before using this medication during pregnancy.

Is Entacom Plus 100mg Tablet safe for breastfeeding women?Arrow

It is not known whether Entacom Plus 100mg Tablet is excreted in breast milk. Consult your doctor before using this medication while breastfeeding.

Is Entacom Plus 100mg Tablet habit-forming?Arrow

No, Entacom Plus 100mg Tablet is not a habit-forming medication.

What things should be avoided while taking Entacom Plus 100mg Tablet?Arrow

Avoid drinking alcohol while taking Entacom Plus 100mg Tablet, as it can increase side effects. Also, avoid driving or operating machinery, as this medication can cause side effects like dizziness or drowsiness.

Can Entacom Plus 100mg Tablet cure Parkinson's disease?Arrow

No, Entacom Plus 100mg Tablet cannot cure Parkinson's disease. It only helps in managing the symptoms.

Are there other brands of Entacom Plus 100mg Tablet available in the market?Arrow

Yes, there may be several other brands of Entacom Plus 100mg Tablet available in the market. Consult your doctor or pharmacist to determine which brand is most suitable for you.

References

Book Icon

Entacapone Tablets, Initial U.S. Approval: 1998. Package insert information from the U.S. Food and Drug Administration. Provides detailed information regarding the drug's indications, dosage, contraindications, warnings, precautions, adverse reactions, drug interactions, and clinical pharmacology.

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DrugBank: Entacapone. Comprehensive information on entacapone including its mechanism of action, pharmacokinetics, metabolism, and interactions.

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European Medicines Agency (EMA) - Comtan (entacapone) EPAR. Public Assessment Report from the EMA providing detailed scientific assessment of entacapone.

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PubMed - Search for 'entacapone'. PubMed is a service of the National Library of Medicine that includes citations from MEDLINE and other life science journals for biomedical articles back to the 1950s.

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LiverTox: Clinical and Research Information on Drug-Induced Liver Injury - Entacapone. Information about the potential for entacapone to cause liver injury.

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INTAS PHARMACEUTICALS LIMITED

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ENTACOM PLUS 100MG TABLET 10'S

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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