gardenal syrup 100 ml
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GARDENAL SYRUP 100 ML

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GARDENAL SYRUP 100 ML

By ABBOTT HEALTH CARE PRIVATE LIMITED

MRP

52.34

₹44.49

15 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Amit Patel

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About GARDENAL SYRUP 100 ML

  • Gardenal syrup is a prescription antiepileptic medicine that contains phenobarbital, a barbiturate used to help control and prevent certain types of seizures. It works by reducing abnormal electrical activity in the brain, thereby lowering the frequency and severity of seizures. Gardenal syrup is often preferred in children or patients who have difficulty swallowing tablets, as the liquid form allows more flexible dose adjustments under medical supervision. This medicine is generally used as a long‑term treatment and should never be started, stopped, or adjusted without a doctor’s advice. Abrupt discontinuation can trigger withdrawal symptoms and may provoke seizures, even in people who have been stable for a long time. The dose and duration are individualized based on age, weight, seizure type, response to treatment, and the presence of other medical conditions or medicines. Gardenal syrup can cause drowsiness, dizziness, slowed thinking, and impaired coordination. Because of this, it may affect school performance in children or the ability to perform tasks that require alertness in adults. Caregivers and patients should closely monitor changes in behavior, mood, or learning ability, and report any concerns to the treating physician. In some individuals, especially children, paradoxical reactions such as irritability, hyperactivity, or agitation may occur. Phenobarbital is metabolized in the liver and eliminated partly through the kidneys, so Gardenal syrup must be used cautiously in people with liver or kidney problems. It can interact with many other medicines by increasing or decreasing their levels in the body, including other antiepileptics, blood thinners, some antibiotics, hormonal contraceptives, and medicines for heart or mental health conditions. Because of these interactions, patients should always inform their doctor and pharmacist about all prescription drugs, over‑the‑counter products, and herbal supplements they are taking. Gardenal syrup may not be suitable for everyone. It is generally avoided or used with great caution in people with a history of severe breathing problems, porphyria, significant liver impairment, or known allergy to barbiturates. Long‑term use can be associated with dependence, tolerance, and, in some cases, effects on bone health or mood. Regular follow‑up, blood tests when advised, and adherence to the prescribed regimen are essential to ensure safe and effective seizure control.

Uses of GARDENAL SYRUP 100 ML

  • Control of seizures in children.
  • Treatment of epilepsy.
  • Management of febrile seizures in infants.
  • Short-term treatment of anxiety.
  • Management of insomnia.
  • Use as a sedative.
  • Treatment for some types of tremors.
  • Treatment of jaundice in newborns.

How GARDENAL SYRUP 100 ML Works

  • GARDENAL SYRUP 100 ML contains Phenobarbital as its active ingredient, which belongs to a class of medications called barbiturates. Phenobarbital primarily works by depressing the central nervous system (CNS). The CNS controls various bodily functions, including brain activity, and when it's slowed down, it can help manage seizures and induce sedation.
  • Specifically, Phenobarbital enhances the action of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter, meaning it reduces nerve excitability throughout the nervous system. By increasing GABA's effectiveness, Phenobarbital helps to decrease neuronal firing, which is often abnormally high during seizures. This calming effect helps to prevent or control epileptic seizures.
  • In simpler terms, imagine the brain as having electrical circuits. During a seizure, these circuits become overactive and fire uncontrollably. Phenobarbital acts like a circuit breaker, calming down the excessive electrical activity and preventing it from spreading throughout the brain. This helps to stop or reduce the severity of seizures.
  • Beyond seizure control, the CNS depressant action of Phenobarbital also contributes to its sedative and hypnotic effects. By slowing down brain activity, it can induce a state of relaxation, drowsiness, and sleepiness. This is why GARDENAL SYRUP 100 ML is sometimes used to manage anxiety or as a short-term sleep aid, although these uses are less common now due to the availability of safer alternatives.
  • It is crucial to understand that GARDENAL SYRUP 100 ML should only be used under the strict supervision of a healthcare professional. The dosage must be carefully determined based on individual needs and medical history. Long-term use can lead to dependence and withdrawal symptoms if the medication is stopped abruptly. Additionally, Phenobarbital can interact with other medications, so it's important to inform your doctor about all other drugs you are taking.
  • Furthermore, GARDENAL SYRUP 100 ML can affect cognitive function and coordination. Patients taking this medication should avoid activities that require alertness, such as driving or operating machinery, until they know how the drug affects them. The syrup's effect can vary among individuals, and regular monitoring by a healthcare provider is essential to ensure its safety and effectiveness.

Side Effects of GARDENAL SYRUP 100 MLArrow

Common side effects of Gardenal Syrup may include drowsiness, sedation, and dizziness. Less common side effects can involve allergic reactions such as skin rash, itching, or hives; breathing difficulties; swelling of the face, lips, or tongue; nausea, vomiting, or constipation; headache; and changes in mood or behavior, including confusion, agitation, or depression. In rare cases, Gardenal can cause more severe side effects like liver problems (indicated by jaundice), blood disorders (leading to increased risk of infection or bleeding), and Stevens-Johnson syndrome (a severe skin reaction). Long-term use may lead to dependence or withdrawal symptoms upon discontinuation. Always consult your doctor if you experience any concerning side effects.

Safety Advice for GARDENAL SYRUP 100 MLArrow

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Allergies

Contraindicated in known allergy

Gardenal syrup must not be used in patients with a known allergy or hypersensitivity to phenobarbital or other barbiturates.

Dosage of GARDENAL SYRUP 100 MLArrow

  • The dosage of GARDENAL SYRUP 100 ML varies significantly depending on the individual's age, weight, medical condition, and response to treatment. It is crucial to adhere strictly to the dosage prescribed by your physician. Self-medication can be dangerous and is strongly discouraged.
  • For adults, the typical starting dose may range from 60 to 250 mg per day, usually divided into two or three doses. The exact dosage will depend on the severity of the condition being treated, such as seizures or anxiety. Your doctor may adjust the dosage gradually to achieve optimal control while minimizing side effects.
  • In children, the dosage is typically calculated based on body weight. The pediatric dose is generally lower than the adult dose, and careful monitoring is essential. Parents should strictly follow the doctor's instructions and use an accurate measuring device to administer the correct dose. Never estimate or use household spoons, as they can lead to inaccurate dosing.
  • For elderly patients or those with liver or kidney problems, a lower starting dose may be necessary due to reduced drug clearance. Regular monitoring of liver and kidney function may be required during treatment with GARDENAL SYRUP 100 ML.
  • The syrup should be taken orally, and it can be administered with or without food. Consistency in timing is important for maintaining stable blood levels of the medication. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • It's important to note that abrupt discontinuation of GARDENAL SYRUP 100 ML can lead to withdrawal symptoms, especially after prolonged use. Therefore, it should only be stopped under the guidance of your physician, who will gradually reduce the dosage to minimize the risk of withdrawal. Take 'GARDENAL SYRUP 100 ML' only as per the prescription by your physician only

What if I miss my dose of GARDENAL SYRUP 100 ML?Arrow

  • If you miss a dose of Gardenal Syrup, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store GARDENAL SYRUP 100 ML?Arrow

  • Keep GARDENAL SYP 100ML away from the reach of children and pets.
  • Store GARDENAL SYP 100ML at room temperature.

Benefits of GARDENAL SYRUP 100 MLArrow

  • GARDENAL SYRUP 100 ML is primarily used to manage and control seizures, making it a crucial medication for individuals diagnosed with epilepsy. By stabilizing the electrical activity in the brain, it reduces the frequency and severity of seizures, allowing patients to lead more normal lives. Regular and consistent use, as prescribed by a healthcare professional, is essential for optimal seizure control.
  • This medication is also effective in treating febrile seizures in children. Febrile seizures, triggered by high fevers, can be frightening for both the child and their parents. GARDENAL SYRUP helps to prevent these seizures by acting as a preventative measure when a child's temperature rises rapidly. Consulting a pediatrician is vital to determine the appropriate dosage and usage for children.
  • GARDENAL SYRUP can be used to manage certain types of anxiety disorders. It has calming properties that help reduce excessive worry and tension. However, it's important to note that it is typically prescribed when other treatments have not been fully effective, and its use in anxiety management should be closely monitored by a healthcare provider due to the potential for dependence and side effects.
  • In some cases, GARDENAL SYRUP is used as a sedative to promote relaxation and sleep, particularly in individuals experiencing insomnia or other sleep disturbances. Its sedative effects help calm the nervous system, making it easier to fall asleep and stay asleep. Due to the risk of tolerance and dependence, it should only be used under strict medical supervision and for short periods.
  • GARDENAL SYRUP can be used as an adjunct treatment for alcohol withdrawal symptoms. It helps manage the agitation, anxiety, and potential seizures that can occur during alcohol withdrawal. Medical supervision is essential during this process to ensure safe and effective detoxification.
  • The precise dosage of GARDENAL SYRUP must be determined by a healthcare professional based on individual factors such as age, weight, medical condition, and other medications being taken. Adhering to the prescribed dosage and schedule is crucial to avoid adverse effects and ensure the medication's effectiveness. Never adjust the dosage without consulting your doctor.
  • Consistent use of GARDENAL SYRUP is essential for maintaining stable blood levels of the medication, which is vital for effective seizure control and symptom management. Any abrupt discontinuation of the medication can lead to withdrawal symptoms or a recurrence of the underlying condition. Always consult with your doctor before making any changes to your medication regimen.
  • Patients taking GARDENAL SYRUP should be aware of potential side effects, which may include drowsiness, dizziness, confusion, and impaired coordination. It is important to avoid activities that require alertness, such as driving or operating heavy machinery, until you know how the medication affects you. Report any concerning side effects to your healthcare provider promptly.
  • Regular monitoring by a healthcare professional is necessary while taking GARDENAL SYRUP to assess its effectiveness and monitor for potential side effects. Blood tests may be required to check drug levels and liver function. This monitoring helps ensure the medication is being used safely and effectively.

How to use GARDENAL SYRUP 100 MLArrow

  • GARDENAL SYRUP 100 ML is an oral medication and should be administered directly into the mouth. Always use a calibrated measuring device, such as a syringe or a measuring spoon, to ensure accurate dosing. Household teaspoons are not accurate and should not be used. The dosage of GARDENAL SYRUP 100 ML varies significantly depending on the individual's age, weight, and the severity of the condition being treated. Therefore, it is crucial to strictly follow the dosage instructions provided by your doctor. Do not increase or decrease the dose without consulting your healthcare provider, even if you feel that the medication is not working effectively.
  • For infants and young children, the syrup can be mixed with a small amount of water or juice to make it easier to swallow. Ensure that the entire dose is consumed. If the child vomits shortly after taking the medication, consult your doctor for further instructions. In older children and adults, the syrup can be taken directly. It is recommended to take GARDENAL SYRUP 100 ML at the same time(s) each day to maintain a consistent level of medication in the body. This helps in achieving optimal therapeutic effects and reduces the likelihood of missed doses. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • GARDENAL SYRUP 100 ML can be taken with or without food. However, taking it with food may help to reduce stomach upset in some individuals. It is essential to inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, that you are currently taking. Certain medications can interact with GARDENAL SYRUP 100 ML, potentially affecting its effectiveness or increasing the risk of side effects. Regular monitoring by your doctor is necessary while taking GARDENAL SYRUP 100 ML to assess its effectiveness and to check for any potential side effects. Do not stop taking GARDENAL SYRUP 100 ML abruptly, as this may lead to withdrawal symptoms or a worsening of your condition. Always consult with your doctor before discontinuing the medication. Proper storage of GARDENAL SYRUP 100 ML is crucial to maintain its efficacy. Keep the syrup in a cool, dry place, away from direct sunlight and heat. Ensure that the bottle is tightly closed when not in use and keep it out of reach of children.

Quick Tips for GARDENAL SYRUP 100 MLArrow

  • **Consistent Dosage is Key:** Administer Gardenal Syrup at the same time(s) each day as prescribed by your doctor to maintain a consistent level of medication in the bloodstream for optimal seizure control. Consistency helps in preventing breakthrough seizures. Do not alter the dosage without consulting your healthcare provider.
  • **Monitor for Side Effects:** Be vigilant in observing for any potential side effects, such as drowsiness, dizziness, nausea, or changes in behavior. Report any concerning symptoms to your doctor immediately. Regular monitoring ensures prompt management of any adverse reactions and helps tailor the treatment plan effectively.
  • **Avoid Alcohol and Other CNS Depressants:** Refrain from consuming alcohol or using other central nervous system (CNS) depressants while taking Gardenal Syrup, as they can intensify the sedative effects and potentially lead to dangerous respiratory depression. This precaution enhances safety and minimizes the risk of complications.
  • **Inform Healthcare Providers:** Always inform all healthcare providers, including dentists and surgeons, that your child is taking Gardenal Syrup. This is crucial for preventing potential drug interactions and ensuring safe and appropriate medical care. Drug interactions can alter the effectiveness of the syrup.
  • **Do Not Abruptly Discontinue:** Never stop administering Gardenal Syrup abruptly, as this can trigger withdrawal seizures. Always consult with your doctor before making any changes to the medication regimen. Gradual dose reduction under medical supervision minimizes the risk of withdrawal symptoms.
  • **Storage Instructions:** Store Gardenal Syrup at room temperature, away from direct sunlight, heat, and moisture. Keep the bottle tightly closed and out of reach of children. Proper storage maintains the syrup's potency and safety.
  • **Dietary Considerations:** Maintain a balanced diet and ensure adequate hydration while your child is on Gardenal Syrup. Certain foods or drinks might interact with the medication, so consult your doctor for specific dietary recommendations. A healthy diet supports overall well-being during treatment.

Food Interactions with GARDENAL SYRUP 100 MLArrow

  • GARDENAL SYRUP 100 ML can be taken with or without food. However, maintaining a consistent routine with regard to food intake is recommended to ensure consistent absorption of the medication. High-fat meals may affect the absorption rate of phenobarbital, potentially altering its effectiveness. Consult your doctor for personalized advice.

FAQs

What is Gardenal Syrup 100 ml used for?Arrow

Gardenal Syrup 100 ml is primarily used to control and prevent seizures (epilepsy). It may also be used to treat anxiety and insomnia.

What are the common side effects of Gardenal Syrup 100 ml?Arrow

Common side effects of Gardenal Syrup 100 ml include drowsiness, dizziness, fatigue, loss of coordination, and nausea.

Can I take Gardenal Syrup 100 ml with food?Arrow

Gardenal Syrup 100 ml can be taken with or without food, but it's important to take it at the same time each day.

What happens if I miss a dose of Gardenal Syrup 100 ml?Arrow

If you miss a dose of Gardenal Syrup 100 ml, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

How should I store Gardenal Syrup 100 ml?Arrow

Store Gardenal Syrup 100 ml at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can Gardenal Syrup 100 ml interact with other medications?Arrow

Yes, Gardenal Syrup 100 ml can interact with certain medications. It's important to tell your doctor about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements.

Is Gardenal Syrup 100 ml safe for pregnant women?Arrow

The safety of using Gardenal Syrup 100 ml during pregnancy has not been established. Pregnant women should consult their doctor before using it.

Is Gardenal Syrup 100 ml safe for breastfeeding women?Arrow

Gardenal Syrup 100 ml can pass into breast milk and may harm a breastfeeding infant. Breastfeeding women should consult their doctor before using it.

What are the symptoms of an overdose of Gardenal Syrup 100 ml?Arrow

Symptoms of an overdose of Gardenal Syrup 100 ml include drowsiness, confusion, slowed breathing, and coma.

How long does it take for Gardenal Syrup 100 ml to work?Arrow

The time it takes for Gardenal Syrup 100 ml to work can vary from person to person. It typically takes a few days to become effective.

Is Gardenal Syrup 100 ml a controlled substance?Arrow

Yes, Gardenal Syrup 100 ml is a controlled substance. It should only be used with a prescription from a doctor.

Can I drink alcohol while taking Gardenal Syrup 100 ml?Arrow

Drinking alcohol while taking Gardenal Syrup 100 ml can increase drowsiness and dizziness. It's best to avoid alcohol while taking this medication.

What happens if I stop taking Gardenal Syrup 100 ml?Arrow

Stopping Gardenal Syrup 100 ml suddenly can cause seizures. It's important to talk to your doctor before stopping this medication.

Is Gardenal Syrup 100 ml safe for children?Arrow

Gardenal Syrup 100 ml can be used in children, but it should be used with caution and as directed by a doctor.

What is the difference between Gardenal and Phenobarbital?Arrow

Gardenal is a brand name for Phenobarbital. Both contain the same active ingredient and are used to treat the same conditions.

What is Gardenal syrup used for?Arrow

Gardenal syrup is primarily used to prevent and control certain types of epileptic seizures. It contains phenobarbital, a barbiturate that stabilizes abnormal electrical activity in the brain. Doctors may also use it in specific situations such as seizure prevention in high‑risk patients or as part of combination therapy with other antiepileptic medicines. Its use is always individualized and requires a valid prescription and regular medical follow‑up.

How does Gardenal syrup work in the body?Arrow

Gardenal syrup contains phenobarbital, which enhances the effect of gamma‑aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. By increasing GABA activity, it reduces the excitability of nerve cells and helps prevent the sudden bursts of electrical activity that cause seizures. This calming effect on the central nervous system can also lead to drowsiness and slowed reaction times, which is why careful monitoring is needed.

Is Gardenal syrup safe for children?Arrow

Gardenal syrup is commonly used in children for seizure control because the liquid form allows more precise dose adjustments based on body weight. However, safety depends on correct prescribing, careful monitoring, and adherence to the doctor’s instructions. Children may experience side effects such as drowsiness, behavioral changes, irritability, or learning difficulties. Any unusual behavior, poor school performance, or worsening seizures should be reported to the pediatrician or neurologist promptly.

Can Gardenal syrup be used in patients with liver problems?Arrow

Gardenal syrup must be used with great caution in patients with liver disease because phenobarbital is largely metabolized in the liver. In moderate to severe liver impairment, the medicine may accumulate and increase the risk of toxicity, excessive sedation, and breathing problems. In some serious liver conditions, it may be contraindicated. Patients with a history of hepatitis, cirrhosis, or abnormal liver tests should inform their doctor before starting Gardenal, and may require dose adjustments and periodic liver function monitoring.

Is Gardenal syrup safe for people with kidney disease?Arrow

In kidney disease, Gardenal syrup should be used carefully and only under close medical supervision. Phenobarbital and its metabolites are partly eliminated through the kidneys, so reduced kidney function can lead to higher blood levels and increased side effects such as drowsiness, confusion, or breathing difficulties. Patients with chronic kidney disease or those on dialysis must inform their doctor, who will decide whether Gardenal is appropriate and whether any dose modification or additional monitoring is needed.

Can Gardenal syrup be taken during pregnancy?Arrow

Use of Gardenal syrup during pregnancy requires a careful risk–benefit assessment by a specialist. Phenobarbital can cross the placenta and has been associated with potential risks to the developing baby, including congenital malformations and effects on growth or neurodevelopment. However, uncontrolled seizures in the mother can also be dangerous for both mother and fetus. Women who are pregnant or planning pregnancy should never stop Gardenal abruptly on their own. Instead, they should consult their neurologist and obstetrician to discuss possible dose adjustments, alternative therapies, folic acid supplementation, and close monitoring throughout pregnancy.

Is Gardenal syrup safe while breastfeeding?Arrow

Phenobarbital passes into breast milk, so Gardenal syrup can expose the nursing infant to the drug. This may cause excessive sleepiness, poor feeding, or breathing difficulties in the baby, especially in premature or medically fragile infants. The decision to breastfeed while taking Gardenal should be made jointly by the mother and her healthcare providers, weighing the benefits of breastfeeding against the potential risks of drug exposure. If breastfeeding is continued, the baby should be closely monitored for unusual drowsiness, poor weight gain, or breathing problems, and medical advice should be sought immediately if these occur.

Can I drive or operate machines while taking Gardenal syrup?Arrow

Gardenal syrup can cause drowsiness, dizziness, slowed reactions, and impaired concentration, all of which can significantly affect the ability to drive or operate machinery safely. Many patients are advised not to drive, especially when starting treatment, after dose changes, or if they still experience seizures. Local driving regulations for people with epilepsy may also apply. Patients should discuss their individual situation with their doctor, and should never drive or perform hazardous tasks if they feel sleepy, confused, or unsteady.

Is it safe to drink alcohol while on Gardenal syrup?Arrow

Alcohol should generally be avoided while taking Gardenal syrup. Both alcohol and phenobarbital depress the central nervous system, and their combined effect can lead to excessive sedation, severe drowsiness, impaired judgment, and increased risk of accidents or breathing problems. Alcohol may also interfere with seizure control and can worsen liver function, which is important for metabolizing phenobarbital. Patients should discuss any alcohol use with their doctor and, in most cases, are advised to abstain completely.

What if I am allergic to barbiturates or other medicines?Arrow

People with a known allergy to phenobarbital or other barbiturates should not use Gardenal syrup. Signs of an allergic reaction can include skin rash, itching, hives, swelling of the face or throat, difficulty breathing, or severe skin reactions such as blistering or peeling. If any of these occur, Gardenal should be stopped immediately and urgent medical care sought. Patients should inform their doctor about all previous drug allergies, including reactions to sedatives, sleeping pills, or antiepileptic medicines, before starting treatment.

Can I stop Gardenal syrup suddenly if I feel better?Arrow

Gardenal syrup should never be stopped abruptly without medical supervision, even if seizures have been well controlled for a long time. Sudden discontinuation can lead to withdrawal symptoms, including anxiety, tremors, insomnia, and, most importantly, rebound seizures or status epilepticus, which can be life‑threatening. If the doctor decides that Gardenal should be reduced or discontinued, the dose is usually tapered gradually over weeks or months while monitoring for seizure recurrence.

Does Gardenal syrup interact with other medicines or birth control pills?Arrow

Gardenal syrup has many potential drug interactions because phenobarbital can increase or decrease the activity of liver enzymes that process other medicines. It can reduce the effectiveness of hormonal contraceptives such as birth control pills, patches, or implants, increasing the risk of unintended pregnancy. It may also affect blood thinners, some antibiotics, antifungals, heart medicines, antidepressants, and other antiepileptics. Patients should provide a complete list of all medicines and supplements to their doctor and pharmacist, and women using hormonal contraception should discuss additional or alternative contraceptive methods.

References

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DrugBank: Phenobarbital. Provides detailed chemical and pharmacological information on Phenobarbital, the active ingredient in Gardenal.

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PubChem: Phenobarbital. Offers comprehensive chemical properties, safety data, and related compounds information.

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FDA Application Details: Luminal (Phenobarbital). Although for Luminal, this FDA resource gives insight into Phenobarbital regulatory information.

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European Medicines Agency (EMA). Useful for finding scientific guidelines and assessments related to Phenobarbital and similar drugs (search required within the EMA site).

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LiverTox: Phenobarbital. Provides information related to Phenobarbital's effects on the liver.

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MedlinePlus: Phenobarbital. Contains general information about the uses and side effects of phenobarbital.

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