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GLEDEPA MET XR 10/1000MG TABLET 7'S

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GLEDEPA MET XR 10/1000MG TABLET 7'S

By ABBOTT HEALTH CARE PRIVATE LIMITED

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418.6

₹355.81

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About GLEDEPA MET XR 10/1000MG TABLET 7'S

  • GLEDEPA MET XR 10/1000MG TABLET 7'S is a combination medication designed to manage type 2 diabetes effectively. It combines two powerful active ingredients: Empagliflozin and Metformin Hydrochloride.
  • Empagliflozin belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine, which helps lower blood sugar levels. This mechanism is particularly beneficial for individuals with type 2 diabetes, as it provides an alternative pathway for glucose control independent of insulin.
  • Metformin Hydrochloride, on the other hand, is a biguanide that reduces glucose production in the liver and improves the body's sensitivity to insulin. It helps to lower blood sugar levels by decreasing the amount of glucose produced by the liver and by helping the body use insulin more effectively. Metformin is a well-established medication for type 2 diabetes and has been used for many years.
  • The extended-release (XR) formulation of GLEDEPA MET XR 10/1000MG TABLET 7'S allows for a once-daily dosage, improving patient compliance and convenience. The combination of Empagliflozin and Metformin provides a dual-action approach to managing blood sugar levels, targeting different pathways in the body to achieve optimal glycemic control.
  • This medication is typically prescribed as part of a comprehensive diabetes management plan that includes diet and exercise. It is important to use GLEDEPA MET XR 10/1000MG TABLET 7'S exactly as prescribed by your healthcare provider. Regular monitoring of blood sugar levels and kidney function is recommended while taking this medication to ensure safety and effectiveness. Individuals with kidney problems should exercise caution and consult their doctor before using this medicine.
  • GLEDEPA MET XR 10/1000MG TABLET 7'S is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is not indicated for use in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.

Uses of GLEDEPA MET XR 10/1000MG TABLET 7'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Used in conjunction with diet and exercise
  • Improving blood sugar control
  • May help reduce the risk of heart disease (with doctor's consultation)
  • May help reduce the risk of kidney disease (with doctor's consultation)

How GLEDEPA MET XR 10/1000MG TABLET 7'S Works

  • GLEDEPA MET XR 10/1000MG TABLET 7'S is a combination medication designed to manage type 2 diabetes effectively. It combines two active ingredients: Empagliflozin and Metformin Hydrochloride. Each component works through different mechanisms to lower blood sugar levels, providing a synergistic effect for improved glycemic control.
  • Empagliflozin belongs to a class of drugs called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Empagliflozin works by selectively inhibiting SGLT2. By blocking this protein, Empagliflozin reduces the reabsorption of glucose in the kidneys, causing excess glucose to be excreted in the urine. This process directly lowers blood glucose levels. Furthermore, the removal of glucose through urine also results in a caloric loss, which can contribute to weight loss – a beneficial effect for many patients with type 2 diabetes. Additionally, Empagliflozin has been shown to provide cardiovascular benefits in certain patient populations, reducing the risk of heart-related complications.
  • Metformin Hydrochloride, on the other hand, is a biguanide antihyperglycemic agent. Its primary mechanism of action involves decreasing glucose production in the liver (hepatic gluconeogenesis) and improving insulin sensitivity in peripheral tissues, such as muscles. By reducing hepatic glucose output, Metformin lowers the amount of glucose released into the bloodstream. Simultaneously, it enhances the uptake and utilization of glucose by muscles and other tissues, thereby improving the body's response to insulin. Unlike some other diabetes medications, Metformin does not typically cause hypoglycemia (low blood sugar) when used alone because it does not stimulate insulin secretion. It also has a favorable effect on lipid profiles and can contribute to modest weight loss or weight stabilization.
  • The extended-release (XR) formulation of GLEDEPA MET ensures a gradual release of Metformin into the body, allowing for once-daily administration and minimizing gastrointestinal side effects that can sometimes occur with immediate-release Metformin. When taken together, Empagliflozin and Metformin complement each other by addressing different aspects of glucose regulation. Empagliflozin helps remove excess glucose from the body, while Metformin reduces glucose production and improves insulin sensitivity. This dual action provides a more comprehensive approach to managing blood sugar levels in individuals with type 2 diabetes. It is crucial to use GLEDEPA MET XR 10/1000MG TABLET 7'S as prescribed by your healthcare provider, in conjunction with a healthy diet and regular exercise, to achieve optimal glycemic control and overall health benefits.

Side Effects of GLEDEPA MET XR 10/1000MG TABLET 7'SArrow

Common side effects of GLEDEPA MET XR 10/1000MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste in the mouth, and headache. Some patients may experience upper respiratory tract infection symptoms like cough, sore throat, and runny nose. Less common but potentially serious side effects include lactic acidosis (symptoms: muscle cramps, severe tiredness, trouble breathing), pancreatitis (severe stomach pain), and allergic reactions (rash, itching, swelling). Kidney problems and liver problems are rare but require immediate medical attention. Low blood sugar (hypoglycemia) can occur, especially when taken with other diabetes medications; symptoms include shakiness, sweating, confusion, and rapid heartbeat. Vitamin B12 deficiency may occur with long-term use. Dizziness and postural hypotension (low blood pressure upon standing) have also been reported. Skin reactions like bullous pemphigoid can occur rarely.

Safety Advice for GLEDEPA MET XR 10/1000MG TABLET 7'SArrow

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Allergies

Allergies

Do not use this medicine if you are allergic to it or any of its ingredients.

Dosage of GLEDEPA MET XR 10/1000MG TABLET 7'SArrow

  • The recommended dosage of GLEDEPA MET XR 10/1000MG TABLET 7'S is individualized based on the patient's current antidiabetic regimen, glycemic control, and tolerability. The usual starting dose is one tablet once daily, taken orally. It is generally recommended to take GLEDEPA MET XR 10/1000MG TABLET 7'S with food to reduce gastrointestinal side effects associated with metformin. The maximum recommended daily dose is one tablet of GLEDEPA MET XR 10/1000MG TABLET 7'S.
  • Dosage adjustments should be made gradually to minimize gastrointestinal side effects and to assess the patient's response. Your doctor will monitor your blood sugar levels regularly to determine the effectiveness of the medication and adjust the dosage accordingly. It is crucial to follow your doctor's instructions carefully and not to change the dosage without consulting them.
  • For patients switching from other antidiabetic medications, your doctor will determine the appropriate starting dose of GLEDEPA MET XR 10/1000MG TABLET 7'S based on your previous medication and blood sugar control. In patients with renal impairment, the dosage may need to be adjusted or the medication may not be suitable. Always inform your doctor about any pre-existing kidney problems or other medical conditions.
  • Take 'GLEDEPA MET XR 10/1000MG TABLET 7'S' only as per the prescription by your physician only.

What if I miss my dose of GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

  • If you miss a dose of GLEDEPA MET XR 10/1000MG TABLET 7'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

  • Keep GLEDEPA MET XR 10/1000MG TAB 1X7 away from the reach of children and pets.
  • Store GLEDEPA MET XR 10/1000MG TAB 1X7 at room temperature.

Benefits of GLEDEPA MET XR 10/1000MG TABLET 7'SArrow

  • GLEDEPA MET XR 10/1000MG TABLET 7'S is a combination medicine specifically designed to manage type 2 diabetes effectively. It combines two powerful medications, Empagliflozin and Metformin, each working through different mechanisms to lower blood sugar levels and provide comprehensive glycemic control.
  • One of the primary benefits of GLEDEPA MET XR is its dual action in reducing blood sugar. Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated through urine, effectively lowering blood sugar levels. Metformin, on the other hand, decreases glucose production in the liver and improves insulin sensitivity, allowing the body to use insulin more effectively. Together, they provide a synergistic effect, leading to better blood sugar management than either medication could achieve alone.
  • Improved Glycemic Control: GLEDEPA MET XR helps to maintain stable blood sugar levels throughout the day, reducing the risk of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). This stability is crucial for preventing long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems.
  • Cardiovascular Benefits: Empagliflozin, one of the active ingredients in GLEDEPA MET XR, has been shown to have cardiovascular benefits. Clinical trials have demonstrated that it can reduce the risk of cardiovascular events, such as heart attack and stroke, in patients with type 2 diabetes who have established cardiovascular disease. This makes GLEDEPA MET XR a valuable option for patients who are at high risk of heart-related complications.
  • Weight Management: GLEDEPA MET XR can aid in weight management. Empagliflozin's mechanism of action, which involves eliminating excess glucose through urine, can lead to a modest amount of weight loss. This can be particularly beneficial for individuals with type 2 diabetes who are also struggling with obesity or overweight, as weight loss can further improve blood sugar control and overall health.
  • Blood Pressure Reduction: Studies have indicated that Empagliflozin can also lead to a slight reduction in blood pressure. This is an added advantage for patients with diabetes, as high blood pressure often coexists with diabetes and increases the risk of cardiovascular complications. By helping to lower blood pressure, GLEDEPA MET XR contributes to overall cardiovascular health.
  • Convenient Once-Daily Dosage: GLEDEPA MET XR is typically taken once daily, which can improve adherence to the medication regimen. The extended-release (XR) formulation ensures a steady release of the medication throughout the day, providing consistent blood sugar control with a single dose. This convenience can make it easier for patients to incorporate the medication into their daily routine.
  • Reduced Risk of Hypoglycemia: While Metformin alone rarely causes hypoglycemia, combining it with certain other diabetes medications can increase the risk. Empagliflozin, however, has a low risk of causing hypoglycemia when used alone or in combination with Metformin. This makes GLEDEPA MET XR a safer option for patients who are concerned about low blood sugar episodes.
  • Kidney Protection: Emerging evidence suggests that Empagliflozin may have protective effects on kidney function in patients with diabetes. Studies have shown that it can slow the progression of kidney disease, reducing the risk of end-stage renal disease and the need for dialysis. This is a significant benefit, as diabetes is a leading cause of kidney failure.
  • Overall, GLEDEPA MET XR 10/1000MG TABLET 7'S offers a comprehensive approach to managing type 2 diabetes by effectively lowering blood sugar levels, providing cardiovascular benefits, aiding in weight management, reducing blood pressure, and potentially protecting kidney function. Its once-daily dosage and low risk of hypoglycemia make it a convenient and safe option for many patients. As with any medication, it is essential to consult with a healthcare professional to determine if GLEDEPA MET XR is the right choice for your individual needs and to discuss any potential risks or side effects.

How to use GLEDEPA MET XR 10/1000MG TABLET 7'SArrow

  • GLEDEPA MET XR 10/1000MG TABLET 7'S should be taken orally, exactly as prescribed by your doctor. It is typically recommended to take this medication once daily, with a meal, preferably in the morning to minimize potential gastrointestinal side effects. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system and may increase the risk of side effects or decrease its effectiveness.
  • Consistency is key for optimal blood sugar control. Try to take GLEDEPA MET XR 10/1000MG TABLET 7'S at the same time each day. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. Adhering to the prescribed dosage and timing is crucial for maintaining stable blood sugar levels.
  • Before starting GLEDEPA MET XR 10/1000MG TABLET 7'S, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Certain medications can interact with GLEDEPA MET XR, potentially affecting its efficacy or increasing the risk of side effects. Your doctor may need to adjust your dosage or monitor you more closely. Also, tell your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart failure, or a history of lactic acidosis.
  • Regular monitoring of your blood sugar levels is essential while taking GLEDEPA MET XR 10/1000MG TABLET 7'S. Your doctor will advise you on how often to check your blood sugar and what your target range should be. It's also important to maintain a healthy lifestyle, including a balanced diet and regular exercise, to maximize the benefits of the medication. This medicine works best when combined with diet and exercise.
  • If you experience any unusual or severe side effects while taking GLEDEPA MET XR 10/1000MG TABLET 7'S, such as persistent nausea, vomiting, abdominal pain, unexplained weight loss, or symptoms of lactic acidosis (such as rapid breathing, muscle pain or cramps, unusual sleepiness), seek immediate medical attention. Do not stop taking the medication without consulting your doctor, as this can lead to a sudden increase in blood sugar levels.
  • Store GLEDEPA MET XR 10/1000MG TABLET 7'S at room temperature, away from moisture and heat. Keep it out of reach of children. Always check the expiration date before taking the medication. If you have any questions or concerns about how to use GLEDEPA MET XR 10/1000MG TABLET 7'S, consult your doctor or pharmacist.

Quick Tips for GLEDEPA MET XR 10/1000MG TABLET 7'SArrow

  • Take GLEDEPA MET XR 10/1000MG TABLET 7'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once daily, usually with the evening meal, to help manage blood sugar levels effectively throughout the day and minimize gastrointestinal side effects.
  • GLEDEPA MET XR 10/1000MG TABLET 7'S is used to improve glycemic control in adults with type 2 diabetes mellitus. It contains empagliflozin and metformin, which work together to lower blood sugar levels through different mechanisms. Empagliflozin helps the kidneys remove glucose from the body via urine, while metformin decreases glucose production in the liver and improves insulin sensitivity.
  • It's crucial to monitor your blood sugar levels regularly while taking GLEDEPA MET XR 10/1000MG TABLET 7'S. Keep a record of your readings and share them with your doctor during your check-ups. This helps your doctor adjust your dosage if needed and ensures that the medication is working effectively for you.
  • Stay hydrated by drinking plenty of water throughout the day while taking GLEDEPA MET XR 10/1000MG TABLET 7'S. This helps your kidneys function properly and reduces the risk of dehydration, especially since empagliflozin increases glucose excretion through urine. Aim for at least 8 glasses of water daily, unless your doctor advises otherwise.
  • Be aware of potential side effects such as urinary tract infections, yeast infections, and changes in urination frequency. Metformin can sometimes cause gastrointestinal issues like nausea, diarrhea, or stomach upset, especially when starting the medication. If you experience any severe or persistent side effects, contact your doctor immediately. Also, inform your doctor about any other medications, supplements, or herbal products you are taking to avoid potential drug interactions.

Food Interactions with GLEDEPA MET XR 10/1000MG TABLET 7'SArrow

  • GLEDEPA MET XR 10/1000MG TABLET 7'S should be taken with food to reduce the risk of stomach upset. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis. Maintain a consistent diet and avoid skipping meals to prevent fluctuations in blood sugar levels. Consult your doctor or pharmacist for personalized dietary advice.

FAQs

What is GLEDEPA MET XR 10/1000MG TABLET 7'S and what is it used for?Arrow

GLEDEPA MET XR 10/1000MG TABLET 7'S is a medication containing a combination of empagliflozin and metformin. It is used to control blood sugar levels in people with type 2 diabetes.

What are the common side effects of GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

Common side effects of GLEDEPA MET XR 10/1000MG TABLET 7'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

How should I take GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

GLEDEPA MET XR 10/1000MG TABLET 7'S should be taken as prescribed by your doctor. It is usually taken once daily with food.

Is GLEDEPA MET XR 10/1000MG TABLET 7'S safe for people with kidney problems?Arrow

GLEDEPA MET XR 10/1000MG TABLET 7'S is not recommended for people with kidney problems. It is important to tell your doctor about your kidney problems before taking this medication.

What happens if I miss a dose of GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

If you miss a dose of GLEDEPA MET XR 10/1000MG TABLET 7'S, take it as soon as you remember. However, if it is close to your next dose, skip the missed dose and continue with your regular dosing schedule.

Can GLEDEPA MET XR 10/1000MG TABLET 7'S be taken with other medications?Arrow

GLEDEPA MET XR 10/1000MG TABLET 7'S can interact with other medications. It is important to tell your doctor about all your medications before taking this medicine.

How should I store GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

Store GLEDEPA MET XR 10/1000MG TABLET 7'S at room temperature, away from heat and moisture.

Is GLEDEPA MET XR 10/1000MG TABLET 7'S safe during pregnancy?Arrow

The safety of GLEDEPA MET XR 10/1000MG TABLET 7'S during pregnancy has not been established. Talk to your doctor before taking this medication if you are pregnant or planning to become pregnant.

What are the symptoms of an overdose of GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

Symptoms of an overdose of GLEDEPA MET XR 10/1000MG TABLET 7'S may include nausea, vomiting, diarrhea, abdominal pain, dizziness, and weakness.

Can I drink alcohol while taking GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

Drinking alcohol is not recommended while taking GLEDEPA MET XR 10/1000MG TABLET 7'S as it may increase the risk of side effects.

What should I tell my doctor before taking GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

Before taking GLEDEPA MET XR 10/1000MG TABLET 7'S, tell your doctor about all your medical conditions and allergies, and about all the medications you are taking.

How does GLEDEPA MET XR 10/1000MG TABLET 7'S control blood sugar?Arrow

GLEDEPA MET XR 10/1000MG TABLET 7'S controls blood sugar in two ways: empagliflozin reduces the reabsorption of glucose by the kidneys, and metformin reduces the production of glucose by the liver and improves insulin sensitivity.

Can GLEDEPA MET XR 10/1000MG TABLET 7'S cause weight loss?Arrow

GLEDEPA MET XR 10/1000MG TABLET 7'S can cause weight loss, but this is not the primary use of the medication.

What are the alternatives to GLEDEPA MET XR 10/1000MG TABLET 7'S?Arrow

Alternatives to GLEDEPA MET XR 10/1000MG TABLET 7'S include other diabetes medications such as sulfonylureas, glitazones, DPP-4 inhibitors, and insulin.

Can GLEDEPA MET XR 10/1000MG TABLET 7'S prevent cardiovascular problems?Arrow

Some studies have shown that GLEDEPA MET XR 10/1000MG TABLET 7'S may reduce the risk of cardiovascular problems, but more research is needed.

References

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FDA application for Qternmet XR (saxagliptin, dapagliflozin, and metformin hydrochloride extended-release) - provides detailed pharmacokinetic and pharmacodynamic information relevant to the drug's components (GLEDEPA MET XR contains similar ingredients)

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DrugBank entry for Metformin - provides detailed information on the mechanism of action, pharmacokinetics, and interactions of metformin.

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DrugBank entry for Dapagliflozin - provides detailed information on the mechanism of action, pharmacokinetics, and interactions of dapagliflozin.

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PMC: Dapagliflozin: a review of its use in type 2 diabetes mellitus - a review of the clinical use, efficacy, and safety of dapagliflozin.

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PMC: Metformin: An update - a review of the clinical use, efficacy, and safety of metformin.

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ABBOTT HEALTH CARE PRIVATE LIMITED

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₹355.81

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