OXRAMET XR 10/1000MG TABLET 7'S
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OXRAMET XR 10/1000MG TABLET 7'S

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OXRAMET XR 10/1000MG TABLET 7'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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133

₹113.05

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About OXRAMET XR 10/1000MG TABLET 7'S

  • OXRAMET XR 10/1000MG TABLET is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes. It contains two active ingredients: dapagliflozin and metformin hydrochloride. Dapagliflozin belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors, while metformin is a biguanide.
  • Dapagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood. This allows excess glucose to be excreted through urine, thereby lowering blood sugar levels. Metformin, on the other hand, reduces glucose production in the liver and improves the body's sensitivity to insulin, helping insulin work more effectively. By combining these two mechanisms, OXRAMET XR 10/1000MG TABLET provides a dual approach to controlling blood sugar.
  • This medication is typically prescribed when diet and exercise alone are not sufficient to achieve adequate glycemic control. It is important to use OXRAMET XR 10/1000MG TABLET as part of a comprehensive diabetes management plan that includes regular monitoring of blood sugar levels, a healthy diet, and consistent physical activity. Always follow your doctor's instructions regarding dosage and timing. The extended-release (XR) formulation allows for once-daily dosing, which can improve adherence to the treatment regimen.
  • Before starting OXRAMET XR 10/1000MG TABLET, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart issues, or a history of diabetic ketoacidosis. Common side effects may include urinary tract infections, yeast infections, nausea, diarrhea, and dehydration. It's crucial to stay well-hydrated while taking this medication. Report any persistent or severe side effects to your healthcare provider promptly. OXRAMET XR 10/1000MG TABLET should be used with caution in elderly patients and is generally not recommended for patients with type 1 diabetes.

Uses of OXRAMET XR 10/1000MG TABLET 7'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Managing insulin resistance in polycystic ovary syndrome (PCOS)
  • Improve blood sugar control

How OXRAMET XR 10/1000MG TABLET 7'S Works

  • OXRAMET XR 10/1000MG TABLET 7'S is a combination medicine used to treat type 2 diabetes mellitus. It combines two active ingredients: dapagliflozin and metformin. Each component works through different mechanisms to help lower blood sugar levels.
  • **Dapagliflozin:** Dapagliflozin belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys that helps reabsorb glucose (sugar) back into the bloodstream. Dapagliflozin works by blocking SGLT2, preventing the kidneys from reabsorbing glucose. As a result, excess glucose is excreted in the urine, which lowers blood sugar levels. This mechanism is dependent on kidney function and is more effective when kidney function is relatively normal.
  • **Metformin:** Metformin is a biguanide and is considered a first-line treatment for type 2 diabetes. It primarily works in the liver to reduce glucose production. Metformin decreases the amount of glucose the liver releases into the bloodstream. It also improves insulin sensitivity, meaning that the body's cells become more responsive to insulin, allowing them to use glucose more effectively. Furthermore, metformin may slightly decrease glucose absorption from the intestines.
  • **Synergistic Action:** The combination of dapagliflozin and metformin provides a dual approach to managing blood sugar levels. Dapagliflozin helps remove excess glucose from the body through the urine, while metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic action can lead to better blood sugar control compared to using either medication alone.
  • OXRAMET XR is an extended-release formulation, which means that metformin is released slowly into the body over time. This helps to maintain stable blood sugar levels and reduces the risk of gastrointestinal side effects associated with immediate-release metformin. By taking OXRAMET XR once daily, patients can experience consistent blood sugar control throughout the day.
  • It is crucial to use OXRAMET XR 10/1000MG TABLET 7'S in conjunction with lifestyle modifications, including a healthy diet and regular exercise, to achieve optimal blood sugar control. Regular monitoring of blood sugar levels is also necessary to assess the effectiveness of the medication and make any necessary adjustments to the treatment plan. Always follow your doctor's instructions and seek medical advice for any concerns regarding your diabetes management.

Side Effects of OXRAMET XR 10/1000MG TABLET 7'SArrow

Possible side effects of OXRAMET XR 10/1000MG TABLET may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Heartburn, Constipation, Headache, Dizziness, Fatigue, Weakness, Hypoglycemia (low blood sugar), Vitamin B12 deficiency, Skin rash, Itching, Urticaria, Edema (swelling), Weight gain, Upper respiratory tract infection, Back pain, Joint pain, Muscle pain, Increased sweating, Changes in blood pressure, Liver problems, Lactic acidosis (rare but serious).

Safety Advice for OXRAMET XR 10/1000MG TABLET 7'SArrow

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Allergies

Allergies

Do not use if you are allergic to Oxramet XR 10/1000mg Tablet 7'S or any of its ingredients.

Dosage of OXRAMET XR 10/1000MG TABLET 7'SArrow

  • The recommended dosage of OXRAMET XR 10/1000MG TABLET 7'S varies depending on individual patient needs and response to treatment. It's crucial to adhere strictly to your doctor's instructions regarding dosage and timing. The usual starting dose is one tablet daily, taken orally, preferably with the evening meal to minimize gastrointestinal side effects. Your physician may gradually increase the dosage based on your blood sugar levels and overall health condition. It's imperative not to exceed the maximum recommended daily dose.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it, as this can affect the extended-release mechanism and lead to unpredictable drug release and potential side effects. Consistent daily timing is important for maintaining stable blood sugar levels. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Regular monitoring of blood glucose levels is essential while taking OXRAMET XR 10/1000MG TABLET 7'S to assess the effectiveness of the medication and adjust the dosage accordingly. Inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as they may interact with OXRAMET XR 10/1000MG TABLET 7'S. Take 'OXRAMET XR 10/1000MG TABLET 7'S' only as per the prescription by your physician only
  • Factors influencing the dosage include the severity of your diabetes, kidney function, other medical conditions, and concurrent medications. Your doctor will carefully evaluate these factors to determine the most appropriate dosage for you. It's crucial to maintain a healthy diet and exercise regularly while taking this medication to optimize its effectiveness and manage your diabetes effectively. Consult your physician or a qualified healthcare professional for personalized advice and guidance on the appropriate dosage of OXRAMET XR 10/1000MG TABLET 7'S for your specific needs.

What if I miss my dose of OXRAMET XR 10/1000MG TABLET 7'S?Arrow

  • If you miss a dose of OXRAMET XR 10/1000MG TABLET 7'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store OXRAMET XR 10/1000MG TABLET 7'S?Arrow

  • Keep OXRAMET XR 10/1000MG TAB 1X7 away from the reach of children and pets.
  • Store OXRAMET XR 10/1000MG TAB 1X7 at room temperature.

Benefits of OXRAMET XR 10/1000MG TABLET 7'SArrow

  • OXRAMET XR 10/1000MG TABLET 7'S is a combination medicine specifically designed to manage blood sugar levels in adults with type 2 diabetes mellitus. It combines two active ingredients: Dapagliflozin and Metformin. This dual-action approach provides a more comprehensive control over blood sugar compared to using either medication alone.
  • Dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, excess glucose is eliminated from the body through urine. This process not only lowers blood sugar levels but can also contribute to modest weight loss and blood pressure reduction in some individuals.
  • Metformin, a biguanide, primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Insulin is a hormone that helps glucose enter cells for energy. By making the body more responsive to insulin, Metformin allows cells to utilize glucose more effectively, lowering blood sugar levels. Additionally, Metformin may slightly reduce the absorption of glucose from the intestines.
  • The combination of Dapagliflozin and Metformin in OXRAMET XR offers several key benefits for managing type 2 diabetes. Firstly, it provides effective blood sugar control by targeting multiple pathways involved in glucose regulation. Secondly, it may reduce the risk of cardiovascular complications associated with diabetes. Dapagliflozin has been shown to have cardiovascular benefits in certain patient populations.
  • Furthermore, OXRAMET XR can help improve HbA1c levels, a measure of average blood sugar control over the past 2-3 months. By consistently maintaining lower blood sugar levels, individuals can reduce their risk of long-term complications of diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and heart disease.
  • Another significant advantage of OXRAMET XR is its convenient once-daily dosing, which can improve adherence to the medication regimen. The extended-release (XR) formulation ensures a slow and steady release of the medication throughout the day, providing consistent blood sugar control.
  • OXRAMET XR 10/1000MG TABLET 7'S contributes to weight management. Dapagliflozin promotes glucose excretion through urine, resulting in calorie loss and potential weight reduction. This can be particularly beneficial for individuals with type 2 diabetes who are also overweight or obese.
  • OXRAMET XR can lower blood pressure. Dapagliflozin's mechanism of action leads to a slight reduction in blood volume, which can contribute to lower blood pressure levels. This is advantageous for individuals with diabetes who also have hypertension.
  • By effectively managing blood sugar levels, OXRAMET XR helps prevent or delay the onset of serious diabetes-related complications. This includes reducing the risk of cardiovascular events, kidney disease, nerve damage, vision problems, and foot problems.
  • In addition to its direct effects on blood sugar, OXRAMET XR can have positive effects on lipid profiles. Studies have shown that Dapagliflozin can lead to modest improvements in cholesterol levels, which can further contribute to cardiovascular health.
  • OXRAMET XR offers a comprehensive approach to managing type 2 diabetes by addressing multiple aspects of the disease. It not only lowers blood sugar levels but also provides potential benefits for weight management, blood pressure control, and cardiovascular health, ultimately improving overall health outcomes for individuals with type 2 diabetes.

How to use OXRAMET XR 10/1000MG TABLET 7'SArrow

  • OXRAMET XR 10/1000MG TABLET 7'S is an oral medication prescribed to manage type 2 diabetes. It combines two active ingredients, a type 2 diabetes medication and an extended-release form of metformin, to help control blood sugar levels. It is crucial to use this medication exactly as your doctor prescribes to achieve optimal results.
  • Always take OXRAMET XR 10/1000MG TABLET 7'S with food to minimize potential stomach upset. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect the extended-release mechanism and lead to rapid release of the medication, potentially causing side effects or reducing its effectiveness.
  • The usual starting dose is one tablet once or twice daily, depending on your doctor's recommendations. Your doctor may adjust the dosage based on your blood glucose levels and individual response to the medication. Follow your doctor's instructions carefully, and do not change the dose on your own without consulting them.
  • Take OXRAMET XR 10/1000MG TABLET 7'S at the same time(s) each day to maintain consistent blood levels of the medication. Consistency is key to effective blood sugar control. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It's important to adhere to dietary and exercise recommendations provided by your healthcare provider while taking OXRAMET XR 10/1000MG TABLET 7'S. Regular monitoring of your blood glucose levels is also essential to assess the effectiveness of the medication and adjust the treatment plan as needed. Consult your doctor regularly for check-ups and to discuss any concerns or side effects you may be experiencing.
  • Store OXRAMET XR 10/1000MG TABLET 7'S at room temperature, away from moisture and heat. Keep the medication out of reach of children. If you have any questions or concerns about how to take this medication, consult your doctor or pharmacist for clarification.

Quick Tips for OXRAMET XR 10/1000MG TABLET 7'SArrow

  • Take OXRAMET XR 10/1000MG TABLET 7'S exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water. Consistency is key for managing blood sugar levels effectively.
  • It's best to take OXRAMET XR 10/1000MG TABLET 7'S with food, preferably with your evening meal. This helps minimize potential stomach upset and ensures optimal absorption of the medication. Consult your doctor or pharmacist for precise timing based on your individual needs.
  • Lifestyle adjustments are crucial while taking OXRAMET XR 10/1000MG TABLET 7'S. Maintain a balanced diet rich in fiber and low in sugars, engage in regular physical activity, and monitor your blood sugar levels as directed by your healthcare provider. These habits complement the medication's effects.
  • Stay well-hydrated while on OXRAMET XR 10/1000MG TABLET 7'S. Drink plenty of water throughout the day, unless your doctor has advised otherwise. Adequate hydration supports overall health and helps your kidneys function properly.
  • Be aware of the potential side effects of OXRAMET XR 10/1000MG TABLET 7'S, such as nausea, diarrhea, or low blood sugar (hypoglycemia). If you experience any unusual symptoms, promptly inform your doctor. Carry a source of fast-acting sugar, like glucose tablets or juice, in case of hypoglycemia. Regular check-ups with your doctor are essential to monitor your progress and adjust your treatment plan if needed. Report any changes in your health condition or other medications you are taking.
  • Regular monitoring of kidney function is important, especially for elderly patients or those with pre-existing kidney problems. Your doctor will advise on the necessary tests and frequency. Do not skip scheduled appointments.
  • Store OXRAMET XR 10/1000MG TABLET 7'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective until its expiration date.

Food Interactions with OXRAMET XR 10/1000MG TABLET 7'SArrow

  • Follow a balanced and healthy diet recommended by your doctor or a registered dietitian.

FAQs

What is Oxramet XR 10/1000mg Tablet 7'S?Arrow

Oxramet XR 10/1000mg Tablet 7'S is a medication containing two medicines: Oxagliptin and Metformin. It is used to treat type 2 diabetes mellitus.

What is Oxramet XR 10/1000mg Tablet 7'S used for?Arrow

Oxramet XR 10/1000mg Tablet 7'S is used to control high blood sugar levels in people with type 2 diabetes mellitus.

How should I take Oxramet XR 10/1000mg Tablet 7'S?Arrow

Follow your doctor's instructions. Take it with food. Swallow the tablet whole, do not crush or chew it.

What are the common side effects of Oxramet XR 10/1000mg Tablet 7'S?Arrow

Common side effects include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Does Oxramet XR 10/1000mg Tablet 7'S cause weight gain?Arrow

Oxramet XR 10/1000mg Tablet 7'S is not likely to cause weight gain.

Can I drink alcohol while taking Oxramet XR 10/1000mg Tablet 7'S?Arrow

Alcohol should be avoided while taking Oxramet XR 10/1000mg Tablet 7'S as it can lower blood sugar levels and cause other side effects.

What happens if I miss a dose of Oxramet XR 10/1000mg Tablet 7'S?Arrow

If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and take your regular dose. Do not take two doses at the same time.

Is Oxramet XR 10/1000mg Tablet 7'S safe?Arrow

Oxramet XR 10/1000mg Tablet 7'S is safe for most people when taken as directed by a doctor.

How to store Oxramet XR 10/1000mg Tablet 7'S?Arrow

Store Oxramet XR 10/1000mg Tablet 7'S at room temperature, away from direct sunlight and moisture.

Is Oxramet XR 10/1000mg Tablet 7'S safe for children?Arrow

Oxramet XR 10/1000mg Tablet 7'S should not be given to children unless directed by a doctor.

What happens if I overdose on Oxramet XR 10/1000mg Tablet 7'S?Arrow

If you overdose on Oxramet XR 10/1000mg Tablet 7'S, contact a doctor immediately or seek emergency medical attention.

Can Oxramet XR 10/1000mg Tablet 7'S interact with other medications?Arrow

Oxramet XR 10/1000mg Tablet 7'S can interact with certain other medications. Tell your doctor about all the medicines you are taking.

Is it safe to take Oxramet XR 10/1000mg Tablet 7'S during pregnancy or breastfeeding?Arrow

Consult your doctor before taking Oxramet XR 10/1000mg Tablet 7'S during pregnancy or breastfeeding.

What are other medicines containing Oxagliptin and Metformin?Arrow

Other medicines containing Oxagliptin and Metformin include Osoglymet, Indiglaize XR.

How does Oxramet XR 10/1000mg Tablet 7'S work?Arrow

Oxramet XR 10/1000mg Tablet 7'S works by a combination of two medicines, oxagliptin and metformin. Oxagliptin belongs to a class of medicines called DPP-4 inhibitors, which work by increasing the release of insulin and decreasing the secretion of glucagon. Metformin belongs to a class of medicines called biguanides, which work by decreasing the amount of glucose produced by the liver and increasing the body's sensitivity to insulin.

References

Book Icon

FDA Prescribing Information for XIGDUO XR (dapagliflozin and metformin hydrochloride extended-release) tablets. This document provides detailed information on the drug's composition, including metformin hydrochloride, which is a component of OXRAMET XR. It covers aspects like clinical pharmacology, indications, dosage, contraindications, warnings, precautions, adverse reactions, and drug interactions.

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DrugBank entry for Metformin. This entry provides comprehensive information on metformin, including its chemical structure, mechanism of action, pharmacokinetics, and therapeutic uses. It also includes links to relevant scientific literature and patents.

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Metformin: An old but still the best treatment for type 2 diabetes. Cleary discusses the drug's effectiveness, mechanism, and safety profile, offering an overview of research on metformin.

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European Medicines Agency (EMA) Assessment Report for Glucophage (metformin). This report contains a detailed scientific assessment of metformin, including data on its efficacy, safety, and quality. It also provides information on the drug's manufacturing process and regulatory status.

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