GLIMZAB MV2 TABLET 15'S

How GLIMZAB MV2 TABLET 15'S Works

• GLIMZAB MV2 Tablet 15'S is a combination medicine designed to manage type 2 diabetes effectively. It combines three active ingredients: Gliclazide, Metformin, and Voglibose, each working through different mechanisms to lower blood glucose levels.
• Gliclazide belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the blood into cells, where it can be used for energy. By increasing insulin secretion, Gliclazide helps to lower blood sugar levels, especially after meals. The action of Gliclazide is glucose-dependent, meaning it releases insulin in response to elevated blood glucose, reducing the risk of hypoglycemia compared to older sulfonylureas.
• Metformin is a biguanide that works mainly by decreasing glucose production in the liver. It reduces the amount of glucose the liver releases into the bloodstream. Additionally, Metformin improves insulin sensitivity, allowing the body's cells to use insulin more effectively. This dual action helps lower both fasting and post-meal blood sugar levels. Metformin also has some effects on glucose absorption in the intestines, further contributing to its blood sugar-lowering effect. Unlike sulfonylureas, Metformin does not stimulate insulin release directly and therefore carries a lower risk of hypoglycemia.
• Voglibose is an alpha-glucosidase inhibitor. It works in the small intestine by inhibiting the enzymes (alpha-glucosidases) that break down complex carbohydrates into simple sugars like glucose. By slowing down carbohydrate digestion and absorption, Voglibose helps to reduce the sharp rise in blood sugar levels that typically occurs after eating. This is particularly beneficial in controlling postprandial hyperglycemia (high blood sugar after meals). Voglibose's action is localized to the gut, and it does not directly affect insulin secretion or sensitivity.
• In combination, these three drugs provide a comprehensive approach to managing blood sugar. Gliclazide boosts insulin secretion, Metformin reduces liver glucose production and enhances insulin sensitivity, and Voglibose slows down carbohydrate absorption. This synergistic effect helps to maintain stable blood sugar levels throughout the day, reducing the risk of both hyperglycemia and hypoglycemia. This combination allows for better glycemic control than any single agent alone, which can improve long-term outcomes for individuals with type 2 diabetes.

Like all medicines, Glimzab MV2 Tablet can cause side effects, although not everybody gets them. **Common Side Effects (May affect up to 1 in 10 people):** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Hypoglycemia (low blood sugar) * Headache * Dizziness **Uncommon Side Effects (May affect up to 1 in 100 people):** * Skin rash * Itching * Urticaria (hives) * Abnormal liver function tests * Weakness * Fatigue * Constipation **Rare Side Effects (May affect up to 1 in 1,000 people):** * Cholestatic jaundice (yellowing of the skin or eyes) * Blood disorders (such as thrombocytopenia, leukopenia, agranulocytosis) **Very Rare Side Effects (May affect up to 1 in 10,000 people):** * Lactic acidosis (symptoms may include deep and rapid breathing, nausea, vomiting, stomach pain) * Severe allergic reactions (anaphylaxis) * Visual disturbances **Frequency Not Known (Frequency cannot be estimated from the available data):** * Pancreatitis (inflammation of the pancreas) * Decreased Vitamin B12 absorption **Important Note:** This is not a complete list of side effects. If you experience any unusual symptoms while taking Glimzab MV2 Tablet, talk to your doctor or pharmacist.

• If you miss a dose of GLIMZAB MV2 TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep GLIMZAB MV2 TAB 1X15 away from the reach of children and pets.
• Store GLIMZAB MV2 TAB 1X15 at room temperature.

• Glimzab MV2 Tablet 15's should be taken orally, preferably with or immediately after meals, to minimize the risk of stomach upset. Consistent timing with meals is advisable to maintain stable blood sugar levels. Avoid excessive alcohol consumption, as it can unpredictably affect blood sugar and increase the risk of side effects. Consult your doctor or pharmacist for further guidance on dietary considerations while taking this medication.