VOGLIMAC GM 2HD TABLET 10'S
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VOGLIMAC GM 2HD TABLET 10'S
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VOGLIMAC GM 2HD TABLET 10'S

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VOGLIMAC GM 2HD TABLET 10'S

By MACLEODS PHARMACEUTICALS PRIVATE LIMITED

MRP

289.5

₹246.08

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About VOGLIMAC GM 2HD TABLET 10'S

  • VOGLIMAC GM 2HD Tablet is a combination medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels in adults when diet and exercise alone are not sufficient. This medication works by increasing insulin sensitivity, reducing glucose production by the liver, and slowing down the absorption of glucose from the intestines.
  • The key ingredients in VOGLIMAC GM 2HD are Voglibose, Gliclazide, and Metformin. Metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity. Gliclazide is a sulfonylurea that stimulates the release of insulin from the pancreas, helping to lower blood sugar levels. Voglibose is an alpha-glucosidase inhibitor that slows down the digestion and absorption of carbohydrates in the small intestine, preventing rapid spikes in blood sugar levels after meals.
  • By combining these three medications, VOGLIMAC GM 2HD offers a comprehensive approach to managing type 2 diabetes. It helps to improve glycemic control throughout the day, reducing the risk of long-term complications associated with diabetes, such as nerve damage, kidney problems, and vision loss. VOGLIMAC GM 2HD is typically taken before meals, as directed by your doctor. It's important to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly while taking this medication. Lifestyle modifications, including a healthy diet and regular exercise, are also essential for managing diabetes effectively.
  • It's crucial to inform your doctor about any other medications you are taking, as well as any existing medical conditions, before starting VOGLIMAC GM 2HD. Common side effects may include nausea, diarrhea, and abdominal discomfort. If you experience any severe or persistent side effects, seek medical attention promptly. This medication is not suitable for individuals with type 1 diabetes or those with severe kidney or liver problems.

Uses of VOGLIMAC GM 2HD TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Controlling blood sugar levels after meals
  • Improving insulin sensitivity
  • Managing insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)

How VOGLIMAC GM 2HD TABLET 10'S Works

  • Voglimac GM 2HD Tablet 10's is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines three active ingredients: Voglibose, Gliclazide, and Metformin Hydrochloride. Each component works through different mechanisms to achieve optimal glycemic control.
  • Voglibose, an alpha-glucosidase inhibitor, functions by slowing down the absorption of carbohydrates from the small intestine into the bloodstream. It competitively inhibits alpha-glucosidase enzymes located in the brush border of the small intestinal cells. These enzymes are responsible for breaking down complex carbohydrates into simpler sugars like glucose. By inhibiting these enzymes, voglibose delays glucose absorption, which helps to prevent a sharp increase in blood sugar levels after meals (postprandial hyperglycemia). This mechanism is particularly beneficial for managing blood sugar spikes that often occur after eating carbohydrate-rich foods.
  • Gliclazide, a sulfonylurea, stimulates the pancreas to release more insulin. It works by binding to specific receptors on the beta cells of the pancreas, leading to the closure of ATP-sensitive potassium channels. This depolarization of the beta cell membrane triggers an influx of calcium ions, which in turn stimulates the release of pre-formed insulin. Gliclazide primarily helps to lower blood sugar levels throughout the day, including fasting blood glucose levels. The increased insulin secretion helps cells utilize glucose more effectively, reducing the amount of glucose circulating in the blood.
  • Metformin Hydrochloride, a biguanide, primarily reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues. It decreases hepatic glucose production by inhibiting gluconeogenesis (the synthesis of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, metformin enhances insulin sensitivity in muscle and other tissues, allowing them to utilize glucose more efficiently. It also slows down the absorption of glucose from the intestine. Metformin does not stimulate insulin release, so it carries a lower risk of hypoglycemia compared to sulfonylureas like gliclazide. The combination of these mechanisms makes metformin a cornerstone in the treatment of type 2 diabetes.
  • In summary, Voglimac GM 2HD Tablet 10's works synergistically to control blood sugar levels through multiple pathways: Voglibose delays carbohydrate absorption, Gliclazide increases insulin secretion, and Metformin reduces hepatic glucose production and enhances insulin sensitivity. This multi-pronged approach helps to achieve better glycemic control in patients with type 2 diabetes compared to using a single medication.

Side Effects of VOGLIMAC GM 2HD TABLET 10'SArrow

Common side effects of Voglimac GM 2HD Tablet may include nausea, vomiting, diarrhea, abdominal pain, flatulence (gas), loss of appetite, and altered taste. Less common but potentially serious side effects include hypoglycemia (low blood sugar), allergic reactions (rash, itching, swelling), liver problems (indicated by jaundice, dark urine, persistent fatigue), and lactic acidosis (rare, but requires immediate medical attention). Other possible side effects are constipation, headache, dizziness, and metallic taste. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for VOGLIMAC GM 2HD TABLET 10'SArrow

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Allergies

Allergies

Do not use Voglimac GM 2HD Tablet if you are allergic to it.

Dosage of VOGLIMAC GM 2HD TABLET 10'SArrow

  • The recommended dosage of VOGLIMAC GM 2HD TABLET 10'S is highly individualized and depends on various factors, including your blood glucose levels, response to treatment, and other medications you may be taking. Your physician will determine the most appropriate dosage for you. Typically, it is taken orally, and it's crucial to adhere strictly to your doctor's instructions regarding timing and frequency.
  • Generally, VOGLIMAC GM 2HD TABLET 10'S is usually prescribed to be taken once or twice daily, preferably before meals. Starting with a low dose and gradually increasing it minimizes the risk of gastrointestinal side effects. Do not exceed the prescribed dosage, as this can increase the risk of adverse effects.
  • It is important to take VOGLIMAC GM 2HD TABLET 10'S consistently at the same times each day to maintain stable blood glucose levels. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.
  • Regular monitoring of your blood glucose levels is essential while taking VOGLIMAC GM 2HD TABLET 10'S to assess its effectiveness and adjust the dosage accordingly. Your doctor may also recommend periodic blood tests to monitor your kidney and liver function. It is crucial to follow up with your healthcare provider regularly to discuss your progress and any concerns you may have.
  • Take 'VOGLIMAC GM 2HD TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of VOGLIMAC GM 2HD TABLET 10'S?Arrow

  • If you miss a dose of Voglimac GM 2HD Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store VOGLIMAC GM 2HD TABLET 10'S?Arrow

  • Keep VOGLIMAC GM 2HD TAB 1X10 away from the reach of children and pets.
  • Store VOGLIMAC GM 2HD TAB 1X10 at room temperature.

Benefits of VOGLIMAC GM 2HD TABLET 10'SArrow

  • Voglimac GM 2HD Tablet 10's is a combination medicine that effectively manages type 2 diabetes mellitus, particularly in individuals whose blood sugar levels are not adequately controlled by diet, exercise, and other antidiabetic medications. This triple-action formulation combines voglibose, metformin, and a sustained-release form of glimepiride to address multiple facets of blood sugar regulation, leading to improved glycemic control and overall health outcomes.
  • One of the primary benefits of Voglimac GM 2HD is its ability to lower both fasting and postprandial (after-meal) blood sugar levels. Voglibose, an alpha-glucosidase inhibitor, works by delaying the absorption of carbohydrates from the small intestine. This action reduces the sharp spikes in blood sugar that typically occur after meals, thus helping to maintain more stable glucose levels throughout the day. Metformin, a biguanide, reduces glucose production in the liver and improves the body's sensitivity to insulin. This helps the body use insulin more effectively to lower blood sugar levels. Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. The sustained-release formulation of glimepiride ensures a gradual and prolonged release of the drug, providing a more consistent insulin response over an extended period.
  • By addressing different mechanisms of blood sugar regulation, Voglimac GM 2HD offers comprehensive glycemic control. This is particularly beneficial for patients who require a multi-pronged approach to manage their diabetes effectively. The combination of voglibose, metformin, and glimepiride can help reduce the risk of long-term complications associated with poorly controlled diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems.
  • Another significant advantage of Voglimac GM 2HD is its convenience. As a single tablet containing three active ingredients, it simplifies the medication regimen for patients, making it easier to adhere to their prescribed treatment plan. This can lead to better compliance and, ultimately, improved health outcomes. Voglimac GM 2HD also helps in reducing insulin resistance, a common problem in type 2 diabetes, where the body's cells do not respond effectively to insulin. By improving insulin sensitivity, the medication helps to lower blood sugar levels and prevent the progression of diabetes.
  • Furthermore, Voglimac GM 2HD can assist in weight management. Metformin, in particular, has been shown to have a modest weight-loss effect in some individuals. This can be a beneficial side effect for overweight or obese patients with type 2 diabetes, as weight loss can further improve blood sugar control and reduce the risk of cardiovascular disease. Voglimac GM 2HD offers a holistic approach to managing type 2 diabetes by targeting multiple pathways involved in glucose metabolism and insulin action. Its use should be accompanied by lifestyle modifications, including a healthy diet, regular exercise, and smoking cessation, to achieve the best possible outcomes in diabetes management. Always consult your healthcare provider for personalized advice and to determine if Voglimac GM 2HD is the right choice for you.

How to use VOGLIMAC GM 2HD TABLET 10'SArrow

  • VOGLIMAC GM 2HD TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It's crucial to use this medication as prescribed by your doctor to manage your blood sugar levels effectively. The typical dosage is usually once or twice daily, ideally just before meals to maximize its effect on postprandial (after-meal) blood glucose spikes. Always swallow the tablet whole with a full glass of water and avoid crushing or chewing it, as this can affect how the medication is released and absorbed.
  • Consistency is key when taking VOGLIMAC GM 2HD TABLET 10'S. Try to take it at the same time(s) each day to help you remember and maintain a steady level of medication in your body. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking VOGLIMAC GM 2HD TABLET 10'S, it's important to adhere to a healthy lifestyle, including a balanced diet and regular exercise. This medication works best when combined with these lifestyle modifications. Monitor your blood sugar levels regularly as directed by your healthcare provider and inform them of any significant changes or concerns. Common side effects may include gastrointestinal discomfort such as bloating or gas. If these side effects persist or worsen, consult your doctor. Also, be aware of symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, or confusion, and consult your doctor if you encounter any of these.
  • It is also important to inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with VOGLIMAC GM 2HD TABLET 10'S. Regular follow-up appointments with your doctor are crucial to monitor your progress and adjust your treatment plan as needed.

Quick Tips for VOGLIMAC GM 2HD TABLET 10'SArrow

  • Take VOGLIMAC GM 2HD TABLET 10'S as prescribed by your doctor, usually before meals, to maximize its effectiveness in controlling blood sugar levels. Consistency is key!
  • Monitor your blood glucose levels regularly as directed by your healthcare provider while taking VOGLIMAC GM 2HD TABLET 10'S. This helps in understanding how the medication is working for you and allows for timely adjustments if needed.
  • Follow a balanced diet and engage in regular physical activity while on VOGLIMAC GM 2HD TABLET 10'S. This holistic approach significantly improves blood sugar control and overall health.
  • Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function, especially important when taking medications like VOGLIMAC GM 2HD TABLET 10'S.
  • Inform your doctor about all other medications, supplements, or herbal remedies you are taking, as drug interactions can affect how VOGLIMAC GM 2HD TABLET 10'S works. This includes over-the-counter medications.
  • Be aware of the symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, dizziness, or confusion. Carry a source of quick-acting sugar with you at all times.
  • Do not skip meals while taking VOGLIMAC GM 2HD TABLET 10'S, as this can lead to hypoglycemia. Ensure that you have regular, balanced meals.
  • If you experience any persistent or bothersome side effects, such as gastrointestinal discomfort, consult your doctor promptly. Do not discontinue the medication without medical advice.
  • Store VOGLIMAC GM 2HD TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children.
  • Attend all scheduled follow-up appointments with your doctor to monitor your progress and address any concerns related to your diabetes management.

Food Interactions with VOGLIMAC GM 2HD TABLET 10'SArrow

  • VOGLIMAC GM 2HD TABLET 10'S is generally taken before meals to maximize its effectiveness in controlling blood sugar levels after eating. However, it is crucial to adhere to your doctor's specific instructions regarding timing and dosage. Consistent timing helps maintain stable blood sugar levels. While there are no specific food restrictions, maintaining a balanced diet is important for managing diabetes effectively. Avoid excessive consumption of sugary foods and simple carbohydrates, as these can lead to rapid spikes in blood sugar levels, counteracting the effects of the medication. Alcohol consumption should be moderate, as it can interact with the medication and affect blood sugar control. Always consult your doctor or a registered dietitian for personalized dietary advice tailored to your individual needs and health condition.

FAQs

What is Voglimac GM 2HD Tablet 10'S?Arrow

Voglimac GM 2HD Tablet 10'S is a medication used to treat type 2 diabetes mellitus. It helps to control blood sugar levels.

How does Voglimac GM 2HD Tablet 10'S work?Arrow

Voglimac GM 2HD Tablet 10'S is a combination of three medicines: Voglibose, Metformin, and Hydrochloride. They work through different mechanisms to lower blood glucose levels after meals.

What are the common side effects of Voglimac GM 2HD Tablet 10'S?Arrow

Common side effects of Voglimac GM 2HD Tablet 10'S include nausea, vomiting, diarrhea, and abdominal pain.

Is Voglimac GM 2HD Tablet 10'S safe during pregnancy?Arrow

There is limited information available regarding the safety of Voglimac GM 2HD Tablet 10'S during pregnancy. Please consult your doctor if you are pregnant or planning to become pregnant.

Is Voglimac GM 2HD Tablet 10'S safe during breastfeeding?Arrow

It is not known whether Voglimac GM 2HD Tablet 10'S is excreted in breast milk. Consult your doctor before breastfeeding.

What is the recommended dosage of Voglimac GM 2HD Tablet 10'S?Arrow

The recommended dosage of Voglimac GM 2HD Tablet 10'S will be determined by your doctor. The dosage will depend on your medical condition and response to treatment.

Can Voglimac GM 2HD Tablet 10'S interact with other medications?Arrow

Voglimac GM 2HD Tablet 10'S can interact with other medications. Tell your doctor about all the medications you are taking, including prescription and over-the-counter drugs.

How to store Voglimac GM 2HD Tablet 10'S?Arrow

Store Voglimac GM 2HD Tablet 10'S at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Does Voglimac GM 2HD Tablet 10'S cause weight gain?Arrow

Voglimac GM 2HD Tablet 10'S does not usually cause weight gain. However, some people may experience it.

Can Voglimac GM 2HD Tablet 10'S cause dizziness?Arrow

Voglimac GM 2HD Tablet 10'S can cause dizziness in some people. If you are feeling dizzy, do not drive or operate machinery.

What happens if I miss a dose of Voglimac GM 2HD Tablet 10'S?Arrow

If you miss a dose of Voglimac GM 2HD Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can I drink alcohol while taking Voglimac GM 2HD Tablet 10'S?Arrow

You should avoid drinking alcohol while taking Voglimac GM 2HD Tablet 10'S as it can increase the risk of side effects.

What precautions should I take while taking Voglimac GM 2HD Tablet 10'S?Arrow

While taking Voglimac GM 2HD Tablet 10'S, monitor your blood sugar levels regularly, eat a healthy diet, and exercise regularly.

What are the alternatives to Voglimac GM 2HD Tablet 10'S?Arrow

Alternatives to Voglimac GM 2HD Tablet 10'S include other oral antidiabetic medications and insulin. Talk to your doctor about the best treatment option for you.

Is Voglimac GM 2HD Tablet 10'S safe for the kidneys?Arrow

Voglimac GM 2HD Tablet 10'S should be used with caution in patients with kidney disease. Consult your doctor if you have any kidney problems.

References

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Voglibose - DrugBank Online. (Provides information on Voglibose, one of the ingredients in VOGLIMAC GM 2HD TABLET). DrugBank.

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Glimepiride - FDA prescribing information. (Provides information on Glimepiride, another ingredient in VOGLIMAC GM 2HD TABLET). U.S. Food & Drug Administration (FDA).

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Efficacy of voglibose as add-on therapy in type 2 diabetes mellitus patients with postprandial hyperglycemia: A systematic review and meta-analysis. (Research article on the efficacy of Voglibose). PMC

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A Review of Glimepiride in the Treatment of Type 2 Diabetes Mellitus. (Research article on Glimepiride). PMC

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MACLEODS PHARMACEUTICALS PRIVATE LIMITED

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