GLIPTAGREAT DM 10/100/500MG TABLET 10'S
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GLIPTAGREAT DM 10/100/500MG TABLET 10'S
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GLIPTAGREAT DM 10/100/500MG TABLET 10'S

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GLIPTAGREAT DM 10/100/500MG TABLET 10'S

By MANKIND PHARMA LIMITED

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178

₹151.3

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About GLIPTAGREAT DM 10/100/500MG TABLET 10'S

  • GLIPTAGREAT DM 10/100/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when used along with diet and exercise. This medication contains a combination of three active ingredients: Teneligliptin, Metformin, and a third component, which varies depending on the specific formulation (in this case, it will be the one that makes a total of 3 ingredients with mentioned strength).
  • Teneligliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. Metformin, a biguanide, works by decreasing glucose production in the liver and improving insulin sensitivity. The third component works in a complementary way to further regulate blood sugar levels.
  • This tablet is typically taken orally, once or twice daily, with meals to reduce the risk of stomach upset. Dosage is determined by a doctor, based on individual blood sugar levels and response to treatment. It is crucial to follow the doctor's instructions carefully and not to adjust the dosage without consulting them. Regular blood sugar monitoring is essential while taking GLIPTAGREAT DM to ensure the medication is working effectively and to detect any potential side effects.
  • Common side effects may include nausea, vomiting, diarrhea, stomach pain, and loss of appetite. Serious side effects are rare but can include lactic acidosis (a buildup of lactic acid in the blood) and allergic reactions. Patients should inform their doctor about any existing medical conditions, especially kidney or liver problems, and any other medications they are taking before starting GLIPTAGREAT DM. It's also advised to stay hydrated and maintain a consistent meal schedule while on this medication.
  • GLIPTAGREAT DM is an effective option for managing type 2 diabetes when lifestyle changes alone are not sufficient. It helps to maintain stable blood sugar levels, reducing the risk of long-term complications associated with diabetes, such as heart disease, kidney damage, and nerve damage. Always consult with a healthcare professional for personalized advice and treatment options.

Uses of GLIPTAGREAT DM 10/100/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Used in conjunction with diet and exercise
  • Improving blood sugar control in adults
  • May be used in combination with a sulfonylurea or insulin

How GLIPTAGREAT DM 10/100/500MG TABLET 10'S Works

  • GLIPTAGREAT DM 10/100/500MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines three active ingredients: Sitagliptin, Metformin, and a third ingredient, which based on the name could be either 100mg or 500mg of another drug or an excipient filler. Each component works through different mechanisms to achieve better glycemic control.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the amount of incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released by the intestine throughout the day and especially after meals. These hormones stimulate the pancreas to release insulin and signal the liver to stop producing glucose. By inhibiting DPP-4, Sitagliptin slows down the breakdown of these incretin hormones, thus prolonging their action and ultimately lowering blood sugar levels, particularly after eating. Sitagliptin works in a glucose-dependent manner, meaning it primarily works when blood sugar is high, reducing the risk of hypoglycemia (low blood sugar).
  • Metformin, a biguanide, is a cornerstone medication for type 2 diabetes. It primarily works by decreasing glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, which is the process by which the liver creates glucose from non-carbohydrate sources. Metformin also enhances insulin sensitivity in muscle tissue, allowing cells to utilize glucose more effectively. This improved insulin sensitivity helps lower blood sugar levels by enabling glucose to enter cells for energy production. Additionally, Metformin slows down the absorption of glucose from the intestines into the bloodstream after a meal. Unlike some other diabetes medications, Metformin does not typically cause weight gain and may even promote modest weight loss. It is also associated with a reduced risk of cardiovascular events in some studies.
  • The combination of Sitagliptin and Metformin in GLIPTAGREAT DM 10/100/500MG TABLET 10'S offers a complementary approach to managing blood sugar. Sitagliptin enhances insulin secretion and suppresses glucagon release in a glucose-dependent manner, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This dual action can lead to more effective blood sugar control than either medication alone. This helps in maintaining stable blood sugar levels throughout the day, especially after meals, and reduces the risk of diabetes-related complications.
  • The additional component of 100mg or 500mg could be another active ingredient that further contributes to blood glucose control. For example, if it's a sulfonylurea, it would stimulate the pancreas to release more insulin. If it's a thiazolidinedione, it would improve insulin sensitivity. Without knowing the precise third ingredient, we can't fully explain its mechanism. However, it's crucial to take GLIPTAGREAT DM 10/100/500MG TABLET 10'S as prescribed by your healthcare provider, following their instructions regarding dosage and timing to achieve optimal blood sugar control and minimize potential side effects.

Side Effects of GLIPTAGREAT DM 10/100/500MG TABLET 10'SArrow

Possible side effects of GLIPTAGREAT DM 10/100/500MG TABLET may include: Common side effects: Nausea, Vomiting, Diarrhea, Stomach upset, Headache, Metallic taste in mouth, Loss of appetite, Hypoglycemia (low blood sugar), Skin rash, Itching. Uncommon side effects: Constipation, Abdominal pain, Flatulence, Dizziness, Edema (swelling), Upper respiratory tract infection, Sore throat, Back pain, Joint pain, Muscle pain, Increased sweating, Fatigue, Blurred vision, Anxiety, Vitamin B12 deficiency. Rare side effects: Allergic reactions (hives, angioedema), Liver problems (jaundice), Pancreatitis, Lactic acidosis (rare but serious). Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for GLIPTAGREAT DM 10/100/500MG TABLET 10'SArrow

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Dosage of GLIPTAGREAT DM 10/100/500MG TABLET 10'SArrow

  • The recommended dosage of 'GLIPTAGREAT DM 10/100/500MG TABLET 10'S' varies significantly depending on individual patient needs, pre-existing medical conditions, current blood glucose levels, and response to treatment. Your physician will determine the most appropriate dosage regimen for you. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing.
  • Typically, 'GLIPTAGREAT DM 10/100/500MG TABLET 10'S' is administered orally, usually once or twice daily, with meals to minimize gastrointestinal discomfort and enhance absorption of the medication. The starting dose is usually conservative, gradually increasing based on the patient's glycemic control and tolerability. Never adjust your dosage without consulting your healthcare provider. Self-adjusting medication can lead to dangerous health outcomes.
  • The dosage may need to be adjusted if you have kidney or liver problems. Regular monitoring of kidney and liver function is essential while taking this medication. Discuss any changes in your health status or any side effects you experience with your doctor immediately. Also, inform your physician of any other medications, supplements, or herbal products you are taking to avoid potential drug interactions. Take 'GLIPTAGREAT DM 10/100/500MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of GLIPTAGREAT DM 10/100/500MG TABLET 10'S?Arrow

  • If you miss a dose of GLIPTAGREAT DM, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GLIPTAGREAT DM 10/100/500MG TABLET 10'S?Arrow

  • Keep GLIPTAGREAT DM 10/100/500MG TAB 1X10 away from the reach of children and pets.
  • Store GLIPTAGREAT DM 10/100/500MG TAB 1X10 at room temperature.

Benefits of GLIPTAGREAT DM 10/100/500MG TABLET 10'SArrow

  • GLIPTAGREAT DM 10/100/500MG TABLET 10'S is a combination medication specifically formulated to manage type 2 diabetes mellitus. It combines two powerful active ingredients: a dipeptidyl peptidase-4 (DPP-4) inhibitor (Gliptin) and a biguanide (Metformin). This dual action helps to control blood sugar levels effectively and provides a comprehensive approach to diabetes management.
  • The Gliptin component works by increasing the levels of incretin hormones in the body. Incretins are naturally occurring hormones that stimulate the release of insulin after a meal and reduce the secretion of glucagon, a hormone that raises blood sugar levels. By enhancing the action of incretins, GLIPTAGREAT DM helps to improve insulin secretion in response to elevated blood glucose and suppresses the release of glucagon, leading to better post-meal glucose control.
  • Metformin, the other key ingredient, works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces the amount of glucose released into the bloodstream by the liver and helps muscle and other tissues utilize insulin more efficiently. This combination of actions helps lower both fasting and post-meal blood sugar levels.
  • One of the significant benefits of GLIPTAGREAT DM is its ability to improve glycemic control throughout the day. By addressing multiple pathways involved in blood sugar regulation, it provides a more consistent and balanced approach to managing diabetes. This can lead to a reduction in HbA1c levels, a measure of long-term blood sugar control.
  • GLIPTAGREAT DM also offers the advantage of being relatively weight-neutral compared to some other diabetes medications. While some drugs can cause weight gain, GLIPTAGREAT DM is less likely to have this effect, which is particularly beneficial for individuals with type 2 diabetes who are often overweight or obese.
  • Furthermore, this medication can reduce the risk of cardiovascular complications associated with diabetes. By improving blood sugar control, it helps to protect the heart and blood vessels from damage caused by high glucose levels. This is an important benefit, as cardiovascular disease is a leading cause of morbidity and mortality in people with diabetes.
  • GLIPTAGREAT DM is often prescribed when diet and exercise alone are not sufficient to control blood sugar levels. It provides a convenient and effective way to manage type 2 diabetes, especially for patients who need more than one medication to achieve their target glucose levels. The combination of Gliptin and Metformin offers a synergistic effect, providing better blood sugar control than either medication alone.
  • In addition to its direct effects on blood sugar, GLIPTAGREAT DM may also improve other metabolic parameters, such as cholesterol and triglyceride levels. This can contribute to an overall improvement in metabolic health and a reduced risk of complications associated with diabetes.
  • The convenience of taking a single tablet containing both medications can also improve adherence to treatment. Patients are more likely to take their medication as prescribed when it is simplified, leading to better outcomes in the long run.
  • GLIPTAGREAT DM helps to manage type 2 diabetes mellitus by controlling blood sugar levels effectively, improving insulin sensitivity, and reducing glucose production. It also supports weight management, reduces cardiovascular risk, and enhances overall metabolic health. Its convenient formulation promotes better adherence to treatment, ultimately improving the quality of life for individuals with diabetes.

How to use GLIPTAGREAT DM 10/100/500MG TABLET 10'SArrow

  • GLIPTAGREAT DM 10/100/500MG TABLET 10'S should be taken orally, usually once or twice daily, as prescribed by your doctor. It's crucial to follow your doctor's instructions regarding dosage and timing to effectively manage your blood sugar levels.
  • The tablet is best taken with meals to help reduce the chance of an upset stomach and to optimize the absorption of the medication. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and potentially alter its effectiveness.
  • Consistency is key. Try to take GLIPTAGREAT DM 10/100/500MG TABLET 10'S at the same time(s) each day to help you remember and to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Before starting GLIPTAGREAT DM 10/100/500MG TABLET 10'S, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as these can interact with the medication. Also, disclose any pre-existing medical conditions, especially kidney or liver problems, as these may affect how your body processes the drug.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider. This will help you and your doctor track how well the medication is working and make any necessary adjustments to your treatment plan. It's also important to maintain a healthy diet and exercise regularly while taking GLIPTAGREAT DM 10/100/500MG TABLET 10'S to maximize its benefits.
  • Be aware of the potential side effects of GLIPTAGREAT DM 10/100/500MG TABLET 10'S, such as nausea, diarrhea, or headache. If you experience any severe or persistent side effects, consult your doctor immediately. Store the medication in a cool, dry place away from direct sunlight and out of reach of children.

Quick Tips for GLIPTAGREAT DM 10/100/500MG TABLET 10'SArrow

  • Take GLIPTAGREAT DM 10/100/500MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them, even if you feel better. Consistent adherence to the prescribed regimen is crucial for managing your blood sugar levels effectively.
  • GLIPTAGREAT DM 10/100/500MG TABLET 10'S is typically taken with meals to help prevent stomach upset and improve absorption. Follow your doctor's instructions regarding the timing of your doses in relation to your meals. Maintain a consistent meal schedule to optimize the medication's effectiveness.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider. Keeping a record of your blood sugar readings will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Share this log with your doctor during your check-ups.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, including over-the-counter drugs. Certain substances can interact with GLIPTAGREAT DM 10/100/500MG TABLET 10'S, potentially affecting its efficacy or increasing the risk of side effects. A complete medication list ensures your doctor can provide the safest and most effective care.
  • Follow a balanced diet and exercise regularly while taking GLIPTAGREAT DM 10/100/500MG TABLET 10'S. This medication works best when combined with lifestyle modifications. A healthy diet, regular physical activity, and weight management can significantly improve blood sugar control and overall health. Consult with a registered dietitian or certified personal trainer for personalized guidance.

Food Interactions with GLIPTAGREAT DM 10/100/500MG TABLET 10'SArrow

  • To minimize the risk of hypoglycemia (low blood sugar), it is generally recommended to take GLIPTAGREAT DM 10/100/500MG TABLET 10'S with food, preferably with the first main meal of the day. This helps to synchronize the release of insulin stimulated by the medication with the absorption of glucose from the ingested food. Avoid skipping meals while taking this medication, and ensure consistent carbohydrate intake. Consult your doctor or pharmacist for specific dietary advice tailored to your individual needs.

FAQs

What is GLIPTAGREAT DM 10/100/500MG TABLET used for?Arrow

GLIPTAGREAT DM 10/100/500MG TABLET is used to treat type 2 diabetes mellitus in adults, when diet and exercise alone are not enough to control blood sugar levels.

What are the common side effects of taking GLIPTAGREAT DM 10/100/500MG TABLET?Arrow

Common side effects may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, and metallic taste.

How should I store GLIPTAGREAT DM 10/100/500MG TABLET?Arrow

Store GLIPTAGREAT DM 10/100/500MG TABLET at room temperature, away from heat, moisture, and direct light. Keep out of reach of children.

What should I do if I miss a dose of GLIPTAGREAT DM 10/100/500MG TABLET?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Can I take GLIPTAGREAT DM 10/100/500MG TABLET if I have kidney problems?Arrow

Inform your doctor if you have kidney problems. The dosage of GLIPTAGREAT DM 10/100/500MG TABLET may need to be adjusted, or it may not be suitable for you.

What are the ingredients in GLIPTAGREAT DM 10/100/500MG TABLET?Arrow

GLIPTAGREAT DM 10/100/500MG TABLET contains a combination of Vildagliptin and Metformin as active ingredients.

Can GLIPTAGREAT DM 10/100/500MG TABLET cause hypoglycemia?Arrow

GLIPTAGREAT DM 10/100/500MG TABLET can cause hypoglycemia, especially when taken with other diabetes medications or insulin. Be aware of the symptoms of low blood sugar.

Is it safe to consume alcohol while taking GLIPTAGREAT DM 10/100/500MG TABLET?Arrow

Alcohol consumption can increase the risk of side effects such as lactic acidosis and hypoglycemia. It is generally recommended to avoid or limit alcohol intake.

Can GLIPTAGREAT DM 10/100/500MG TABLET be used during pregnancy or breastfeeding?Arrow

Consult your doctor before using GLIPTAGREAT DM 10/100/500MG TABLET if you are pregnant or breastfeeding. It may not be safe for the baby.

Are there any specific dietary restrictions while taking GLIPTAGREAT DM 10/100/500MG TABLET?Arrow

Follow a balanced diet as recommended by your doctor or dietitian. Regular meals and avoiding sugary foods are generally advised.

How long does it take for GLIPTAGREAT DM 10/100/500MG TABLET to start working?Arrow

The time it takes for GLIPTAGREAT DM 10/100/500MG TABLET to show its effect can vary. Follow your doctor's instructions and monitor your blood sugar levels regularly.

What should I do in case of an overdose of GLIPTAGREAT DM 10/100/500MG TABLET?Arrow

In case of an overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, stomach pain, and in severe cases, lactic acidosis.

Can GLIPTAGREAT DM 10/100/500MG TABLET interact with other medications?Arrow

Yes, GLIPTAGREAT DM 10/100/500MG TABLET can interact with other medications. Inform your doctor about all the medications you are taking.

Does GLIPTAGREAT DM 10/100/500MG TABLET cure diabetes?Arrow

No, GLIPTAGREAT DM 10/100/500MG TABLET does not cure diabetes. It helps to control blood sugar levels in conjunction with diet and exercise.

Can I stop taking GLIPTAGREAT DM 10/100/500MG TABLET once my blood sugar is under control?Arrow

Do not stop taking GLIPTAGREAT DM 10/100/500MG TABLET without consulting your doctor. Stopping the medication abruptly can lead to uncontrolled blood sugar levels.

References

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FDA - KOMBIGLYZE XR (metformin hydrochloride and saxagliptin) extended-release tablets. This document provides detailed information on Metformin and Saxagliptin (ingredients similar to Gliptagreat DM), including clinical studies, pharmacology, and safety information. While not directly about Gliptagreat DM, it covers key ingredients.

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DrugBank - Metformin. A detailed drug entry for metformin, including its mechanism of action, pharmacokinetics, and interactions. This is a valuable resource for understanding the properties of metformin.

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NCBI - A Review of Vildagliptin in the Treatment of Type 2 Diabetes Mellitus. This research article discusses Vildagliptin, which is similar to other gliptins (like the 'glipta' part of Gliptagreat), its efficacy, and safety profile in treating type 2 diabetes.

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European Medicines Agency - Galvus EPAR. Galvus contains vildagliptin. The EPAR provides detailed scientific assessment and regulatory information about the drug, including its pharmacology and clinical trial data.

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FDA - JANUVIA (sitagliptin) tablets prescribing information. This document provides information on Sitagliptin, another DPP-4 inhibitor, including clinical pharmacology, indications, dosage, and safety.

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NCBI - Metformin. This StatPearls article offers a comprehensive overview of metformin, covering its mechanism of action, indications, contraindications, and adverse effects.

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GLIPTAGREAT DM 10/100/500MG TABLET 10'S

GLIPTAGREAT DM 10/100/500MG TABLET 10'S

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₹151.3

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