JALRA TRIO TABLET 10'S
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JALRA TRIO TABLET 10'S
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JALRA TRIO TABLET 10'S

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JALRA TRIO TABLET 10'S

By USV PRIVATE LIMITED

MRP

179

₹152.15

15 % OFF

₹15.22 Only /

Tablet

10

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Product DetailsArrow

About JALRA TRIO TABLET 10'S

  • Jalra Trio Tablet 10's is a combination medication designed to manage type 2 diabetes effectively. It contains three active ingredients: vildagliptin, metformin hydrochloride, and pioglitazone. This triple combination targets multiple pathways involved in blood sugar control, offering a comprehensive approach to diabetes management.
  • Vildagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amount of incretin hormones in the body. These hormones help to regulate blood sugar levels by stimulating insulin release from the pancreas and reducing the production of glucagon, a hormone that raises blood sugar. By enhancing the action of incretin hormones, vildagliptin helps to lower blood sugar levels, particularly after meals.
  • Metformin hydrochloride is a biguanide that decreases glucose production in the liver and improves insulin sensitivity in the body's tissues. It reduces the amount of sugar released into the bloodstream and helps cells utilize insulin more effectively. Metformin is a cornerstone in the treatment of type 2 diabetes and has been shown to have beneficial effects on cardiovascular health.
  • Pioglitazone is a thiazolidinedione (TZD) that enhances insulin sensitivity in peripheral tissues such as fat and muscle. By improving the body's response to insulin, pioglitazone helps lower blood sugar levels. It also has the potential to improve other metabolic parameters, such as lipid profiles.
  • Jalra Trio is typically prescribed when diet and exercise, along with other antidiabetic medications, are not sufficient to control blood sugar levels. It is taken orally, usually once or twice daily, with meals. It is important to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly while taking this medication. Potential side effects may include gastrointestinal upset, such as nausea, diarrhea, or abdominal pain. Consult your healthcare provider if you experience any persistent or bothersome side effects. This medication is a prescription drug and should only be taken under the guidance of a qualified healthcare professional. It is contraindicated in patients with severe renal impairment, hepatic disease and heart failure.

Uses of JALRA TRIO TABLET 10'S

  • Treatment of Type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Used in conjunction with diet and exercise
  • For use in adults
  • Improving insulin sensitivity
  • Reducing postprandial glucose
  • Reducing basal glucose

How JALRA TRIO TABLET 10'S Works

  • JALRA TRIO TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients, each working through different mechanisms to control blood sugar levels: Vildagliptin, Metformin, and a third drug (details may vary based on specific formulation, but often includes a sulfonylurea or a thiazolidinedione). Understanding how each component works is crucial to appreciating the overall action of this medication.
  • Vildagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a vital role in regulating blood sugar. They stimulate insulin release from the pancreas when blood glucose levels are high and suppress glucagon secretion (a hormone that raises blood sugar) when blood glucose levels are low. By inhibiting DPP-4, vildagliptin increases the levels of active incretin hormones in the body. This leads to improved insulin secretion and reduced glucagon secretion in a glucose-dependent manner, ultimately helping to lower blood sugar levels after meals and throughout the day.
  • Metformin, a biguanide, works primarily by reducing glucose production in the liver. The liver is a major source of glucose in the body, and in people with type 2 diabetes, the liver often produces too much glucose. Metformin decreases hepatic glucose production by inhibiting gluconeogenesis (the process of making glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscle and fat. This means that the body's cells are better able to respond to insulin and take up glucose from the bloodstream. Metformin also slows down the absorption of glucose from the intestines, further contributing to its blood sugar-lowering effect.
  • The combination of these three drugs provides a multi-pronged approach to managing type 2 diabetes. Vildagliptin enhances the body's natural ability to regulate blood sugar through incretin hormones, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic action helps to achieve better glycemic control than could be achieved with either drug alone. It's important to note that JALRA TRIO TABLET 10'S should be used in conjunction with a healthy diet and regular exercise to maximize its effectiveness. Adherence to prescribed dosage and regular monitoring of blood glucose levels are also essential for safe and effective diabetes management with this medication.
  • In summary, JALRA TRIO TABLET 10'S works by combining the actions of Vildagliptin (increasing incretin hormone activity), and Metformin (reducing liver glucose production and improving insulin sensitivity), leading to improved blood sugar control in individuals with type 2 diabetes. Always consult your healthcare provider for personalized medical advice.

Side Effects of JALRA TRIO TABLET 10'SArrow

The common side effects of Jalra Trio Tablet may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), and headache. Less common but potentially serious side effects include lactic acidosis (symptoms: fast, shallow breathing, nausea, vomiting, stomach pain), pancreatitis (severe stomach pain radiating to the back), allergic reactions (rash, itching, swelling), liver problems (yellowing of skin/eyes), and kidney problems. Muscle pain, respiratory tract infection and Vitamin B12 deficiency are also possible.

Safety Advice for JALRA TRIO TABLET 10'SArrow

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Allergies

Allergies

Do not use Jalra Trio Tablet 10's if you are allergic to it.

Dosage of JALRA TRIO TABLET 10'SArrow

  • The recommended dosage of 'JALRA TRIO TABLET 10'S' varies depending on individual patient needs, blood glucose levels, and other medications you may be taking. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing. Typically, 'JALRA TRIO TABLET 10'S' is administered once or twice daily, preferably with meals to minimize gastrointestinal discomfort and optimize drug absorption. Your physician will determine the most appropriate dose for you, considering factors such as your HbA1c level, fasting plasma glucose, and overall health status. The initial dose may be adjusted gradually to achieve optimal glycemic control.
  • Do not self-adjust the dosage of 'JALRA TRIO TABLET 10'S'. Any changes in dosage should only be made under the guidance and supervision of your healthcare provider. Regular monitoring of blood glucose levels is essential while taking this medication to ensure it is effectively managing your diabetes. If you experience any unusual side effects or have concerns about your dosage, promptly contact your doctor.
  • Missing a dose of 'JALRA TRIO TABLET 10'S' can affect your blood sugar control. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. It's important to maintain a consistent dosing schedule to maintain stable blood glucose levels. Take 'JALRA TRIO TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of JALRA TRIO TABLET 10'S?Arrow

  • If you miss a dose of Jalra Trio Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store JALRA TRIO TABLET 10'S?Arrow

  • Keep JALRA TRIO TAB 1X10 away from the reach of children and pets.
  • Store JALRA TRIO TAB 1X10 at room temperature.

Benefits of JALRA TRIO TABLET 10'SArrow

  • JALRA TRIO TABLET 10'S is a combination medicine used to effectively manage type 2 diabetes mellitus. It combines three different oral antidiabetic drugs to provide comprehensive glycemic control. The benefits of using JALRA TRIO include significant improvements in blood sugar levels, reducing the risk of diabetes-related complications, and enhancing overall metabolic health.
  • One of the primary benefits of JALRA TRIO is its ability to lower both fasting and postprandial (after-meal) blood glucose levels. By targeting multiple pathways involved in glucose metabolism, it helps maintain stable blood sugar throughout the day. This is particularly important for preventing hyperglycemia, which can lead to serious health problems over time.
  • JALRA TRIO combines the actions of a DPP-4 inhibitor (like vildagliptin), a biguanide (metformin), and a thiazolidinedione (pioglitazone). Vildagliptin enhances the levels of incretin hormones, which stimulate insulin release and reduce glucagon secretion, both of which help lower blood sugar. Metformin reduces glucose production in the liver and improves insulin sensitivity in the body's tissues, allowing cells to use glucose more effectively. Pioglitazone improves insulin sensitivity in peripheral tissues and reduces hepatic glucose production. Together, these three medications work synergistically to provide better glycemic control than any single drug could achieve alone.
  • Another significant benefit is the potential reduction in the risk of long-term complications associated with diabetes. Poorly controlled diabetes can lead to a range of complications, including cardiovascular disease, nerve damage (neuropathy), kidney disease (nephropathy), and eye damage (retinopathy). By maintaining stable blood sugar levels, JALRA TRIO can help reduce the likelihood of developing these complications, thereby improving long-term health outcomes.
  • JALRA TRIO offers the convenience of a single tablet containing three different medications. This simplifies the treatment regimen for patients, making it easier to adhere to their prescribed medication schedule. Improved adherence can lead to better glycemic control and overall health benefits.
  • Patients using JALRA TRIO often experience improvements in their overall well-being. By effectively managing blood sugar levels, they may notice reduced fatigue, increased energy levels, and improved quality of life. These improvements can have a positive impact on daily activities and overall productivity.
  • Regular monitoring and consultation with a healthcare provider are essential when taking JALRA TRIO to ensure its effectiveness and safety. The dosage may need to be adjusted based on individual response and tolerance. Additionally, lifestyle modifications, such as a healthy diet and regular exercise, are crucial for maximizing the benefits of JALRA TRIO and achieving optimal diabetes management.

How to use JALRA TRIO TABLET 10'SArrow

  • JALRA TRIO TABLET 10'S is a prescription medication and should be used exactly as your doctor directs. The usual starting dose is one tablet, taken orally, once or twice daily. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this may affect how the medication is released into your system.
  • Consistency is key for optimal results. Try to take JALRA TRIO TABLET 10'S at the same time(s) each day, preferably with meals. This helps maintain a steady level of the medication in your bloodstream. If you miss a dose, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Before starting JALRA TRIO TABLET 10'S, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Certain medications can interact with JALRA TRIO TABLET 10'S, affecting its effectiveness or increasing the risk of side effects. Also, let your doctor know about any pre-existing medical conditions you may have, especially kidney problems, liver problems, or heart problems. Regular monitoring of your blood sugar levels is essential while taking this medication. Follow your doctor's instructions carefully and attend all scheduled appointments.
  • It is important to maintain a healthy lifestyle while taking JALRA TRIO TABLET 10'S. This includes following a balanced diet, engaging in regular physical activity, and avoiding excessive alcohol consumption. These lifestyle modifications can help improve blood sugar control and overall health. If you experience any unusual side effects or have any concerns, contact your doctor immediately. Do not stop taking JALRA TRIO TABLET 10'S without consulting your doctor, as this could lead to a worsening of your condition. Store the tablets in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Quick Tips for JALRA TRIO TABLET 10'SArrow

  • Take JALRA TRIO TABLET 10'S as prescribed by your doctor. It's usually taken orally, with or without food, once or twice daily. Follow your doctor's instructions carefully regarding dosage and timing to maintain consistent blood sugar levels.
  • JALRA TRIO TABLET 10'S contains a combination of medications to manage blood sugar. Consistency is key! Take it at the same time(s) each day to get the most benefit and remember that it works best when combined with a healthy diet and regular exercise.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting JALRA TRIO TABLET 10'S. This helps prevent potential drug interactions that could affect how well the medication works or increase the risk of side effects. Be especially cautious about medications affecting kidney function.
  • Monitor your blood sugar levels regularly as directed by your doctor or diabetes educator. Keeping a log of your blood sugar readings can help you and your healthcare provider assess how well JALRA TRIO TABLET 10'S is working and make any necessary adjustments to your treatment plan. Report any significant changes or concerns to your doctor.
  • Be aware of the signs and symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, rapid heartbeat, and confusion. Carry a source of fast-acting sugar, like glucose tablets or juice, with you at all times to treat hypoglycemia promptly. If you experience frequent episodes of low blood sugar, consult your doctor to adjust your medication or diet.
  • Stay hydrated by drinking plenty of water throughout the day. This helps your kidneys function properly, which is especially important when taking JALRA TRIO TABLET 10'S. Dehydration can sometimes affect blood sugar levels, so adequate fluid intake is essential for overall health and effective diabetes management.
  • If you are planning to undergo any surgery or medical procedure, inform your doctor that you are taking JALRA TRIO TABLET 10'S. It may be necessary to adjust your medication dosage or temporarily discontinue it before the procedure to avoid complications. Always follow your doctor's instructions closely in such situations.

Food Interactions with JALRA TRIO TABLET 10'SArrow

  • JALRA TRIO TABLET 10'S should be taken orally as directed by your doctor. It is recommended to take this medicine with food, preferably with the first main meal of the day, to reduce the chances of stomach upset. Avoid excessive alcohol consumption while taking this medicine, as it can increase the risk of hypoglycemia (low blood sugar).

FAQs

What is Jalra Trio Tablet 10'S?Arrow

Jalra Trio Tablet 10'S is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

What are the active ingredients in Jalra Trio Tablet 10'S?Arrow

Jalra Trio Tablet 10'S contains vildagliptin, metformin, and glimepiride.

What is Jalra Trio Tablet 10'S used for?Arrow

Jalra Trio Tablet 10'S is used to treat type 2 diabetes mellitus. It helps to lower blood sugar levels.

What are the common side effects of Jalra Trio Tablet 10'S?Arrow

Common side effects of Jalra Trio Tablet 10'S include nausea, vomiting, diarrhea, abdominal pain, and headache.

Is Jalra Trio Tablet 10'S safe for patients with kidney problems?Arrow

Jalra Trio Tablet 10'S should be used with caution in patients with kidney problems, as it can worsen kidney function. Dosage adjustments may be needed.

Is Jalra Trio Tablet 10'S safe for pregnant women?Arrow

The safety of Jalra Trio Tablet 10'S during pregnancy is not established. It should only be used if the benefit outweighs the risks.

How should Jalra Trio Tablet 10'S be stored?Arrow

Jalra Trio Tablet 10'S should be stored at room temperature, away from direct sunlight and heat. Keep it out of reach of children.

Should Jalra Trio Tablet 10'S be taken with food?Arrow

It is recommended to take Jalra Trio Tablet 10'S with or after food to minimize the risk of stomach upset.

What happens if I miss a dose of Jalra Trio Tablet 10'S?Arrow

If you miss a dose of Jalra Trio Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can Jalra Trio Tablet 10'S cause weight gain?Arrow

Jalra Trio Tablet 10'S can cause weight gain in some patients, especially if taken with other diabetes medications.

Can Jalra Trio Tablet 10'S be taken with other medications?Arrow

Jalra Trio Tablet 10'S can interact with other medications. Tell your doctor about all the medicines you are taking, including over-the-counter drugs and herbal supplements.

How long should I take Jalra Trio Tablet 10'S?Arrow

The dosage and duration of Jalra Trio Tablet 10'S will be determined by your doctor. Take it only as prescribed by your doctor.

Can Jalra Trio Tablet 10'S cause hypoglycemia?Arrow

Jalra Trio Tablet 10'S can cause hypoglycemia (low blood sugar), especially if taken with other diabetes medications. Symptoms of hypoglycemia include shakiness, sweating, dizziness, and confusion.

Are there alternatives to Jalra Trio Tablet 10'S?Arrow

Yes, there are several other medications available to treat type 2 diabetes. Talk to your doctor about the best option for you.

What to do in case of overdose of Jalra Trio Tablet 10'S?Arrow

If you suspect you have taken an overdose of Jalra Trio Tablet 10'S, seek immediate medical attention.

References

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Efficacy and Safety of Vildagliptin Plus Metformin as Initial Combination Therapy in Patients With Type 2 Diabetes Mellitus: A 24-Week, Randomized, Double-Blind, Placebo-Controlled Trial

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Systematic review and network meta-analysis of combination therapy with metformin for type 2 diabetes: a network meta-analysis

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Kombiglyze XR (metformin hydrochloride and saxagliptin) prescribing information

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Metformin drug record on DrugBank

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Vildagliptin drug record on DrugBank

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European Medicines Agency Galvus (vildagliptin) EPAR

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