GLYCOMET GP3/850MG TABLET 10'S

How GLYCOMET GP3/850MG TABLET 10'S Works

• GLYCOMET GP3/850MG TABLET is a combination medication designed to manage type 2 diabetes mellitus. It combines three active ingredients: glimepiride, pioglitazone, and metformin, each working through different mechanisms to lower blood glucose levels effectively. This triple combination provides a comprehensive approach to glycemic control, addressing multiple aspects of insulin resistance and secretion.
• Metformin, a biguanide, is the cornerstone of treatment for many individuals with type 2 diabetes. It primarily works by decreasing glucose production in the liver. Specifically, metformin inhibits hepatic gluconeogenesis, the process by which the liver generates glucose from non-carbohydrate sources. Additionally, it enhances insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more efficiently. Metformin also slows down the absorption of glucose from the intestines, further contributing to lower postprandial (after-meal) blood sugar spikes. It activates AMPK (AMP-activated protein kinase), a cellular energy sensor, which plays a key role in these beneficial effects.
• Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. It achieves this by binding to specific receptors on pancreatic beta cells, which triggers a cascade of events leading to the secretion of insulin. Insulin then helps glucose move from the bloodstream into cells, where it can be used for energy. Glimepiride is particularly effective at reducing fasting blood glucose levels. It should be taken with caution as it can sometimes cause hypoglycemia (low blood sugar), especially if meals are skipped or delayed.
• Pioglitazone, a thiazolidinedione (TZD), improves insulin sensitivity in peripheral tissues, similar to metformin, but through a different mechanism. Pioglitazone activates PPARγ (peroxisome proliferator-activated receptor gamma), a nuclear receptor that regulates the expression of genes involved in glucose and lipid metabolism. By activating PPARγ, pioglitazone enhances the uptake and utilization of glucose in muscles and adipose (fat) tissue. It also reduces glucose production in the liver. Pioglitazone helps lower both fasting and postprandial blood glucose levels and can also have beneficial effects on lipid profiles.
• In summary, GLYCOMET GP3/850MG TABLET works by targeting three key aspects of type 2 diabetes: reducing hepatic glucose production (metformin), stimulating insulin secretion (glimepiride), and improving insulin sensitivity in peripheral tissues (pioglitazone). This multifaceted approach helps to achieve better glycemic control compared to using any single drug alone. However, it's important to use this medication under the guidance of a healthcare professional, as they can adjust the dosage and monitor for potential side effects, such as hypoglycemia or weight gain. Regular monitoring of blood glucose levels is crucial to ensure the medication is working effectively and safely.

Possible side effects of Glycomet GP3/850mg Tablet may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Hypoglycemia (low blood sugar), Headache, Dizziness, Weakness, Fatigue, Skin rash, Itching, Vitamin B12 deficiency, Lactic acidosis (rare but serious). Contact your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of GLYCOMET GP3/850MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep GLYCOMET GP3/850MG TAB 1X10 away from the reach of children and pets.
• Store GLYCOMET GP3/850MG TAB 1X10 at room temperature.

• Take Glycomet GP3/850mg Tablet as prescribed by your doctor, usually once daily with your main meal. This helps to reduce the likelihood of stomach upset and also optimizes the absorption of the medication.
• It's crucial to adhere to your diet and exercise plan while taking Glycomet GP3/850mg. This medication works best when combined with a healthy lifestyle, improving blood sugar control and overall well-being. Regular physical activity, such as brisk walking for at least 30 minutes most days of the week, can significantly enhance the effects of the medicine.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. Keeping a record of your blood sugar readings helps you and your doctor understand how well the medication is working and allows for timely adjustments to your treatment plan if needed. Use a reliable blood glucose meter and follow the instructions carefully.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, dizziness, and confusion. Carry a source of fast-acting sugar with you, like glucose tablets or juice, in case your blood sugar drops too low. If you experience these symptoms, consume the fast-acting sugar and check your blood sugar levels promptly.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking before starting Glycomet GP3/850mg. Some medications can interact with this drug, potentially affecting its efficacy or increasing the risk of side effects. It’s important to provide a complete list to ensure your doctor can make informed decisions about your treatment.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function and helps to flush out excess glucose. Aim for at least 8 glasses of water daily, unless otherwise directed by your doctor, especially if you are physically active or live in a warm climate.
• Do not skip meals while taking Glycomet GP3/850mg. Maintaining a regular eating schedule helps prevent significant fluctuations in blood sugar levels. If you need to adjust your meal times, discuss it with your healthcare provider to avoid potential complications.
• Attend all scheduled appointments with your doctor and undergo regular check-ups, including blood tests. These appointments are essential for monitoring your overall health, assessing the effectiveness of your treatment, and making any necessary adjustments to your medication or lifestyle plan. Regular monitoring helps to prevent or manage potential complications associated with diabetes.

• It is advisable to take GLYCOMET GP3/850MG TABLET 10'S with food to minimize the risk of gastrointestinal side effects. Consistent timing with meals is recommended to maintain stable blood sugar levels. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia.