GOLBI SR 450MG TABLET 10'S
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GOLBI SR 450MG TABLET 10'S
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GOLBI SR 450MG TABLET 10'S

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GOLBI SR 450MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

709

₹602.65

15 % OFF

₹60.27 Only /

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About GOLBI SR 450MG TABLET 10'S

  • GOLBI SR 450MG TABLET 10'S is prescribed to dissolve certain gallstones and prevent their recurrence. It is also effective in treating primary biliary cirrhosis, a specific type of liver disease. This medication works by breaking down cholesterol that has accumulated and hardened into stones within the gallbladder, thus facilitating their dissolution. It's crucial to adhere to your doctor's instructions regarding dosage and duration of treatment for optimal results.
  • For best results, GOLBI SR 450MG TABLET 10'S should be swallowed whole after a meal, accompanied by a glass of milk or water. The appropriate dosage is determined by the condition being treated and individual body weight. Consistent and regular intake, as prescribed over several months or longer, is essential to maximize its therapeutic benefits. Continue the medication even if symptoms improve or disappear, unless otherwise directed by your healthcare provider.
  • Common side effects associated with this medicine may include abdominal pain, diarrhea, hair loss, itching, nausea, and skin rash. However, not all individuals experience these side effects. If you experience any bothersome or persistent side effects, it is important to inform your doctor for appropriate guidance and management. They can provide advice on how to alleviate these effects or adjust your treatment plan if necessary.
  • Before commencing treatment with this medication, inform your doctor about any pre-existing conditions, especially if you have inflammation of the gallbladder or bile ducts, experience frequent cramp-like pain in the upper abdomen, have a history of coughing up blood, or have recently gained weight rapidly. GOLBI SR 450MG TABLET 10'S can interact with other medications, potentially altering their effects, so disclose all medications you are currently taking to your doctor. Women using hormonal birth control pills should consider alternative methods, as these pills can increase gallstone formation. During treatment, regular monitoring through ultrasound scans or blood tests to assess liver function may be necessary.

Uses of GOLBI SR 450MG TABLET 10'S

  • Treatment of Primary biliary cirrhosis. GOLBI SR 450MG TABLET 10'S helps manage symptoms and promote liver health in primary biliary cirrhosis.
  • Treatment of Gallbladder stones. GOLBI SR 450MG TABLET 10'S helps manage symptoms and promote gallbladder health in Gallbladder stones.

How GOLBI SR 450MG TABLET 10'S Works

  • GOLBI SR 450MG TABLET 10'S is a hepatoprotective medication designed to support and maintain liver health. It functions through multiple mechanisms to safeguard the liver and improve its overall function. Primarily, it plays a crucial role in cholesterol management by actively reducing the levels of cholesterol circulating in the bloodstream. This action is particularly beneficial in dissolving gallbladder stones, especially those primarily composed of cholesterol, offering a non-surgical approach to managing this condition.
  • Beyond cholesterol management, GOLBI SR 450MG TABLET 10'S actively works to enhance liver function by improving liver enzyme levels. Elevated liver enzymes often indicate liver stress or damage, and this medication aids in normalizing these levels, promoting a healthier liver environment. Furthermore, it provides a protective shield to liver cells, guarding them against injury and damage caused by toxic bile acids. By mitigating the harmful effects of these acids, the tablet supports the structural integrity and functionality of the liver cells.
  • In essence, GOLBI SR 450MG TABLET 10'S operates comprehensively to lower cholesterol, dissolve gallbladder stones, improve liver enzyme levels, and protect liver cells, ultimately contributing to enhanced liver function and overall well-being.

Side Effects of GOLBI SR 450MG TABLET 10'SArrow

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

  • Abdominal pain
  • Diarrhea
  • Hair loss
  • Itching
  • Nausea
  • Rash

Safety Advice for GOLBI SR 450MG TABLET 10'SArrow

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Liver Function

Consult a Doctor

There is limited information available on the use of GOLBI SR 450MG TABLET 10'S in patients with liver disease. Please consult your doctor.

Dosage of GOLBI SR 450MG TABLET 10'SArrow

  • Dosage for children: The dosage of GOLBI SR 450MG TABLET 10'S for children depends on their body weight and the specific liver disorder being treated. It is typically prescribed by a pediatrician or gastroenterologist who will determine the appropriate dosage.
  • Dosage for Adults: The recommended dosage of GOLBI SR 450MG TABLET 10'Sfor adults varies depending on the indication. For gallstone dissolution, the usual dose is 8-10 mg/kg body weight per day, divided into two to three doses. In the treatment of primary biliary cholangitis (PBC), the typical dose ranges from 13-15 mg/kg body weight per day, also divided into multiple doses. However, dosages may differ based on individual patient factors, and it is essential to follow the specific instructions provided by a healthcare professional.

How to store GOLBI SR 450MG TABLET 10'S?Arrow

  • Keep GOLBI SR 450MG TAB 1X10 away from the reach of children and pets.
  • Store GOLBI SR 450MG TAB 1X10 at room temperature.

Benefits of GOLBI SR 450MG TABLET 10'SArrow

  • <b>Treatment of Primary Biliary Cholangitis</b><br>Primary biliary cholangitis (PBC) is a chronic liver disease that progresses slowly. While it may not always present noticeable symptoms initially, it can eventually lead to liver failure if left unmanaged. GOLBI SR 450MG TABLET 10'S is a medication prescribed to treat PBC, either alone or in combination with other medications. It works by potentially preventing or delaying liver damage, especially when treatment commences during the early stages of the disease. This medication is often a lifelong commitment. To enhance the effectiveness of GOLBI SR 450MG TABLET 10'S and promote overall well-being, consider lifestyle adjustments such as smoking cessation, maintaining a healthy weight, and moderating alcohol consumption. Regular monitoring by your healthcare provider is essential to assess the medication's efficacy and adjust the treatment plan as needed. Early diagnosis and treatment with GOLBI SR 450MG TABLET 10'S can significantly improve the long-term prognosis for individuals with PBC. Consistent adherence to the prescribed dosage and schedule is crucial for optimal results. Discuss any concerns or side effects with your doctor promptly.
  • <b>Treatment of Gallbladder Stones</b><br>GOLBI SR 450MG TABLET 10'S is also prescribed to address gallbladder stones by reducing the amount of cholesterol produced by the liver. This action aids in breaking down cholesterol that has accumulated and formed into stones within the gallbladder. Dissolving gallstones completely can take several months of consistent treatment, therefore, it's important to adhere to the prescribed dosage and duration. In addition to GOLBI SR 450MG TABLET 10'S, your doctor may recommend other medications or lifestyle modifications to further reduce cholesterol levels and prevent the recurrence of gallstones. These may include dietary changes, weight management, and other cholesterol-lowering agents. Regular check-ups and imaging tests, such as ultrasound, may be necessary to monitor the progress of gallstone dissolution and ensure the effectiveness of the treatment plan. Consult your doctor for a comprehensive evaluation and personalized recommendations for managing gallbladder stones.

How to use GOLBI SR 450MG TABLET 10'SArrow

  • It is crucial to adhere to your doctor's instructions regarding the dosage and duration of GOLBI SR 450MG TABLET 10'S. Deviating from the prescribed regimen can impact the effectiveness of the medication and potentially lead to adverse effects.
  • Administer the tablet orally, swallowing it whole with a glass of water. Avoid crushing, chewing, or breaking the tablet, as this can alter the way the medication is absorbed into your system.
  • For optimal absorption and to minimize potential stomach upset, GOLBI SR 450MG TABLET 10'S should be taken with food. This helps ensure that the medication is properly processed by your body, maximizing its benefits.
  • Consistency is key when taking GOLBI SR 450MG TABLET 10'S. Try to take it at the same time each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • If you have any concerns or questions about how to take GOLBI SR 450MG TABLET 10'S, do not hesitate to consult your doctor or pharmacist for clarification. They can provide personalized guidance based on your individual medical history and needs.

Quick Tips for GOLBI SR 450MG TABLET 10'SArrow

  • Take GOLBI SR 450MG TABLET 10'S after a meal, accompanied by a glass of milk or water to aid absorption and minimize potential stomach upset. Consistent timing is important for optimal effectiveness.
  • Maintain a healthy lifestyle by eating a balanced diet rich in fruits, vegetables, and whole grains. Engage in regular physical activity to support overall well-being and complement the effects of the medication. It's also advisable to avoid alcohol consumption while taking this medication.
  • Diarrhea is a possible side effect. To manage this, drink plenty of fluids to prevent dehydration. If diarrhea persists for more than a few days or if you notice blood in your stools, contact your doctor immediately. Do not self-treat.
  • Your doctor will likely monitor your liver function and bilirubin levels regularly. Expect monthly monitoring for the first three months of therapy, followed by every six months thereafter. These tests are crucial to ensure the medication isn't adversely affecting your liver.
  • It's essential to continue taking GOLBI SR 450MG TABLET 10'S as prescribed by your doctor. Do not discontinue the medication abruptly without consulting them, as this could lead to a return of symptoms or other complications. Always seek professional medical advice before making any changes to your medication regimen.

FAQs

<h3 class=bodySemiBold>When should I take GOLBI SR 450MG TABLET 10'S?</h3>Arrow

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. GOLBI SR 450MG TABLET 10'S should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.

<h3 class=bodySemiBold>Is GOLBI SR 450MG TABLET 10'S safe?</h3>Arrow

GOLBI SR 450MG TABLET 10'S is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

<h3 class=bodySemiBold>How does GOLBI SR 450MG TABLET 10'S help the liver?</h3>Arrow

GOLBI SR 450MG TABLET 10'S acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

<h3 class=bodySemiBold>Does GOLBI SR 450MG TABLET 10'S cause weight gain?</h3>Arrow

Yes, there is a chance of weight gain with GOLBI SR 450MG TABLET 10'S, but it is not common. The use of GOLBI SR 450MG TABLET 10'S can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.

<h3 class=bodySemiBold>What should I avoid while taking GOLBI SR 450MG TABLET 10'S?</h3>Arrow

While taking GOLBI SR 450MG TABLET 10'S, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of GOLBI SR 450MG TABLET 10'S. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of GOLBI SR 450MG TABLET 10'S. So, ask your doctor about the time gap that should be maintained between GOLBI SR 450MG TABLET 10'S and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the GOLBI SR 450MG TABLET 10'S.

References

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Ursodiol. Birmingham, Alabama: Axcan Pharma US, Inc.; 1997 (online) Available from:

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Ursodiol. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 1997 (online) Available from:

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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20] (online) Available from:

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Ursodeoxycholic [Package Insert]. Mumbai, India: Alkem Laboratories Ltd.; 2016. (online) Available from:

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The Lancet. Gastroenterology and Hepatology. (online) Available from:

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INTAS PHARMACEUTICALS LIMITED

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India

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MRP

709

₹602.65

15 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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