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GOLBI SR 450MG TABLET 15'S
GOLBI SR 450MG TABLET 15'S
By INTAS PHARMACEUTICALS LIMITED
MRP
₹
857.25
₹728.66
15 % OFF
₹48.58 Only /
TabletCheck Delivery
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Product Details
About GOLBI SR 450MG TABLET 15'S
- GOLBI SR 450MG TABLET 15'S is a medication primarily prescribed to dissolve certain types of gallstones and prevent their recurrence. It's also effective in managing primary biliary cirrhosis, a specific type of liver disease. This medication functions by breaking down cholesterol that has solidified into stones within the gallbladder, facilitating their dissolution. For optimal absorption and effectiveness, GOLBI SR 450MG TABLET 15'S should be swallowed whole after a meal, accompanied by a glass of milk or water.
- The dosage of GOLBI SR 450MG TABLET 15'S varies depending on the specific condition being treated and the individual's body weight. To achieve the best possible outcome, it's crucial to take the medication regularly and consistently for the entire duration prescribed by your doctor, which may extend for several months or even longer. It's important to continue taking the medication as directed, even if symptoms improve or disappear.
- Common side effects associated with GOLBI SR 450MG TABLET 15'S include abdominal pain, diarrhea, hair loss, itching, nausea, and skin rash. However, it's important to note that not everyone experiences these side effects. If you encounter any of these side effects and they cause concern or persist over time, it's advisable to inform your doctor.
- Before commencing treatment with GOLBI SR 450MG TABLET 15'S, it's essential to inform your doctor about any pre-existing medical conditions, such as inflammation of the gallbladder or bile ducts, frequent cramp-like pain in the upper abdomen, coughing up blood, or rapid weight gain. This medication may interact with other medications, either reducing or increasing their effects, so it's crucial to provide your doctor with a comprehensive list of all medications you are currently taking. Women using hormonal birth control pills should consider alternative methods, as these pills can increase gallstone formation. During treatment, regular ultrasound scans or blood tests may be necessary to monitor liver function.
Uses of GOLBI SR 450MG TABLET 15'S
- Treatment of Primary biliary cirrhosis. The functionality of the liver is improved by using this medicine thus improving the quality of life.
- Treatment of Gallbladder stones. This medication helps in dissolving gallstones, potentially reducing the need for surgery.
How GOLBI SR 450MG TABLET 15'S Works
- GOLBI SR 450MG TABLET 15'S is a medication designed to protect the liver and improve its overall function. It belongs to a class of drugs known as hepatoprotective agents, which means it helps shield the liver from damage and promotes its health. One of its primary functions is to lower the levels of cholesterol circulating in the bloodstream. By reducing cholesterol, it aids in dissolving gallstones that are predominantly made up of cholesterol, offering relief and potentially preventing the need for more invasive treatments.
- Furthermore, GOLBI SR 450MG TABLET 15'S has a positive impact on liver enzymes. Elevated liver enzymes often indicate liver stress or damage, and this medication helps to bring these levels back to a more normal range. This indicates an improvement in liver health and function. Additionally, it safeguards liver cells from injury caused by toxic bile acids. Bile acids, while essential for digestion, can become harmful when their levels are too high or when the liver isn't functioning properly. This tablet helps to neutralize these toxic effects, further protecting the liver.
- In essence, GOLBI SR 450MG TABLET 15'S works through multiple mechanisms to support liver health. It lowers cholesterol to dissolve gallstones, improves liver enzyme levels to indicate better function, and protects liver cells from damage caused by toxic bile acids. This comprehensive approach makes it a valuable tool in managing various liver conditions and promoting overall well-being.
Side Effects of GOLBI SR 450MG TABLET 15'S
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
- Abdominal pain
- Diarrhea
- Hair loss
- Itching
- Nausea
- Rash
Safety Advice for GOLBI SR 450MG TABLET 15'S

Liver Function
Consult a DoctorThere is limited information available on the use of GOLBI SR 450MG TABLET 15'S in patients with liver disease. Please consult your doctor.
Dosage of GOLBI SR 450MG TABLET 15'S
- Dosage for children: The dosage of GOLBI SR 450MG TABLET 15'S for children depends on their body weight and the specific liver disorder being treated. It is typically prescribed by a pediatrician or gastroenterologist who will determine the appropriate dosage.
- Dosage for Adults: The recommended dosage of GOLBI SR 450MG TABLET 15'Sfor adults varies depending on the indication. For gallstone dissolution, the usual dose is 8-10 mg/kg body weight per day, divided into two to three doses. In the treatment of primary biliary cholangitis (PBC), the typical dose ranges from 13-15 mg/kg body weight per day, also divided into multiple doses. However, dosages may differ based on individual patient factors, and it is essential to follow the specific instructions provided by a healthcare professional.
How to store GOLBI SR 450MG TABLET 15'S?
- Keep GOLBI SR 450MG TAB 1X15 away from the reach of children and pets.
- Store GOLBI SR 450MG TAB 1X15 at room temperature.
Benefits of GOLBI SR 450MG TABLET 15'S
- <b>Treatment of Primary Biliary Cholangitis:</b><br>Primary biliary cholangitis (PBC) is a chronic liver disease that progresses slowly. While it may not always present noticeable symptoms initially, it can eventually lead to liver failure if left unmanaged. GOLBI SR 450MG TABLET 15'S is a medication prescribed to treat PBC, either as a standalone treatment or in combination with other medications. It is most effective when started in the early stages of the disease, helping to prevent or delay liver damage in many individuals. This treatment is typically a long-term commitment, often required for the rest of your life. To enhance the effectiveness of GOLBI SR 450MG TABLET 15'S and promote overall health, it is advisable to quit smoking, maintain a healthy weight, and moderate alcohol consumption.
- <b>Treatment of Gallbladder Stones:</b><br>GOLBI SR 450MG TABLET 15'S is also prescribed to reduce cholesterol production in the liver. This action aids in breaking down cholesterol that has accumulated and formed into gallstones within the gallbladder. Dissolving gallstones completely may take several months of consistent medication. Therefore, it is crucial to adhere to the prescribed dosage and duration for optimal results. Your doctor may also recommend other medications and lifestyle adjustments to further lower cholesterol levels and minimize the likelihood of gallstone formation. Consulting with your doctor is essential to determine the best course of action for your specific situation. Remember, proactive management and adherence to medical advice are key to successful treatment and prevention of related complications.
- Furthermore, regular check-ups with your healthcare provider are crucial to monitor your progress and adjust your treatment plan as needed. Early detection and consistent management can significantly improve your long-term health outcomes. In addition to medication and lifestyle changes, your doctor may also recommend dietary adjustments to support your liver health and overall well-being.
How to use GOLBI SR 450MG TABLET 15'S
- Always take GOLBI SR 450MG TABLET 15'S exactly as your doctor has advised. It is crucial to follow their instructions regarding the dose and how long to take the medicine for. Deviating from the prescribed dosage or duration can impact the effectiveness of the treatment and may lead to unwanted side effects.
- Swallow the tablet whole with a glass of water. Avoid chewing, crushing, or breaking the tablet, as this can affect how the medicine is released and absorbed by your body. Some medications are designed to release slowly over time, and altering the tablet can disrupt this process.
- It is best to take GOLBI SR 450MG TABLET 15'S with food. Taking it with food can help to reduce the likelihood of stomach upset and can also improve the absorption of the medicine into your bloodstream. If you experience any persistent stomach discomfort, consult your doctor.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
- If you have any concerns about how to take GOLBI SR 450MG TABLET 15'S, or experience any unusual symptoms, do not hesitate to contact your doctor or pharmacist for clarification.
Quick Tips for GOLBI SR 450MG TABLET 15'S
- Take GOLBI SR 450MG TABLET 15'S after a meal, accompanied by a full glass of milk or water to aid digestion and absorption. This helps to minimize potential stomach upset and ensures the medication is effectively processed by your body. Consistency in timing, ideally at the same time each day, will provide optimal therapeutic benefits.
- Complement your medication with a commitment to a healthy lifestyle. Emphasize a balanced diet rich in fruits, vegetables, and lean proteins to support overall well-being. Regular physical activity, tailored to your fitness level and preferences, is vital for maintaining a healthy weight and boosting your immune system. Abstaining from alcohol is crucial, as it can interfere with the medication and potentially harm your liver.
- Be mindful of potential side effects, such as diarrhea. To manage this, ensure you drink plenty of fluids to stay hydrated. Electrolyte-rich solutions can be beneficial in maintaining balance. If diarrhea persists or you observe blood in your stools, promptly inform your doctor for further evaluation and guidance. Do not self-treat; seek professional medical advice.
- Your doctor will closely monitor your liver function and bilirubin levels, particularly during the initial months of treatment. Expect monthly check-ups for the first three months after starting therapy, followed by less frequent monitoring every six months thereafter. This is to ensure the medication is not adversely affecting your liver and to make any necessary adjustments to your treatment plan.
- It is important to adhere to your prescribed treatment regimen. Do not abruptly discontinue GOLBI SR 450MG TABLET 15'S without first consulting your doctor. Stopping the medication prematurely can lead to a relapse of your condition. Your doctor will provide guidance on the appropriate duration and method for discontinuing the medication, if necessary.
FAQs
When should I take GOLBI SR 450MG TABLET 15'S?

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. GOLBI SR 450MG TABLET 15'S should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.
Is GOLBI SR 450MG TABLET 15'S safe?

GOLBI SR 450MG TABLET 15'S is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.
How does GOLBI SR 450MG TABLET 15'S help the liver?

GOLBI SR 450MG TABLET 15'S acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.
Does GOLBI SR 450MG TABLET 15'S cause weight gain?

Yes, there is a chance of weight gain with GOLBI SR 450MG TABLET 15'S, but it is not common. The use of GOLBI SR 450MG TABLET 15'S can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.
What should I avoid while taking GOLBI SR 450MG TABLET 15'S?

While taking GOLBI SR 450MG TABLET 15'S, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of GOLBI SR 450MG TABLET 15'S. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of GOLBI SR 450MG TABLET 15'S. So, ask your doctor about the time gap that should be maintained between GOLBI SR 450MG TABLET 15'S and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the GOLBI SR 450MG TABLET 15'S.
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INTAS PHARMACEUTICALS LIMITED
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India
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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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