IGNALIS M 50/500MG TABLET 10'S
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IGNALIS M 50/500MG TABLET 10'S

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IGNALIS M 50/500MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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About IGNALIS M 50/500MG TABLET 10'S

  • IGNALIS M 50/500MG TABLET is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes. It contains two active ingredients: Vildagliptin and Metformin Hydrochloride. This dual-action approach helps to improve glycemic control when diet and exercise alone are not sufficient.
  • Vildagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amount of certain natural substances that lower blood sugar. Specifically, it helps the pancreas release more insulin when blood sugar is high and reduces the amount of sugar produced by the liver.
  • Metformin Hydrochloride is a biguanide that decreases glucose production in the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. It's a widely used and effective medication for managing blood sugar levels.
  • IGNALIS M 50/500MG TABLET is typically taken orally, usually twice daily with meals to reduce stomach upset. The dosage is determined by your doctor based on your individual needs and response to treatment. It is crucial to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly.
  • This medication is often prescribed as part of a comprehensive diabetes management plan that includes diet, exercise, and regular medical check-ups. While taking IGNALIS M 50/500MG TABLET, it's important to be aware of potential side effects, which may include nausea, vomiting, diarrhea, stomach pain, and headache. Serious side effects are rare but can occur. Always consult with your healthcare provider if you experience any unusual or concerning symptoms.

Uses of IGNALIS M 50/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Inducing ovulation in polycystic ovary syndrome (PCOS)
  • Improving blood sugar control

How IGNALIS M 50/500MG TABLET 10'S Works

  • IGNALIS M 50/500MG TABLET is a combination medicine containing two active ingredients: Vildagliptin and Metformin. These work together to control high blood sugar levels in people with type 2 diabetes. To understand how IGNALIS M works, it's important to understand the role of each ingredient:
  • **Vildagliptin:** Vildagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1), are released from the gut after a meal. They stimulate the release of insulin from the pancreas and reduce the secretion of glucagon from the liver. By inhibiting DPP-4, vildagliptin increases the levels of active incretin hormones in the body. This leads to: 1. Increased insulin release: When blood sugar levels are high, vildagliptin helps the pancreas release more insulin, which helps to lower blood sugar. 2. Decreased glucagon secretion: Vildagliptin reduces the production of glucagon, a hormone that raises blood sugar levels by stimulating the liver to release stored glucose.
  • **Metformin:** Metformin is a biguanide that works primarily by reducing glucose production in the liver and improving insulin sensitivity in the body's tissues. It does this through several mechanisms: 1. Decreased hepatic glucose production: Metformin suppresses gluconeogenesis, the process by which the liver produces glucose from non-carbohydrate sources. 2. Increased insulin sensitivity: Metformin makes the body's cells more responsive to insulin, allowing them to take up glucose from the blood more effectively. 3. Decreased intestinal glucose absorption: Metformin can slightly reduce the absorption of glucose from the intestines after a meal.
  • **Synergistic Effect:** When vildagliptin and metformin are combined in IGNALIS M, they provide a synergistic effect in controlling blood sugar levels. Vildagliptin enhances insulin secretion and reduces glucagon secretion, while metformin reduces glucose production in the liver and improves insulin sensitivity. This combination helps to address multiple aspects of type 2 diabetes, leading to better blood sugar control than either medication alone.
  • **Overall, IGNALIS M 50/500MG TABLET works by:** Enhancing insulin release when blood sugar is high. Reducing glucagon secretion to prevent the liver from releasing excess glucose. Decreasing glucose production in the liver. Improving the body's sensitivity to insulin. Reducing glucose absorption from the intestine. It's important to take IGNALIS M as prescribed by your doctor and to follow their recommendations for diet and exercise to achieve the best possible blood sugar control.

Side Effects of IGNALIS M 50/500MG TABLET 10'SArrow

Common side effects of Ignalis M 50/500mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Some patients might also experience headache, dizziness, fatigue, or weakness. Less common but potentially serious side effects include lactic acidosis (symptoms like rapid breathing, stomach pain, and muscle cramps), allergic reactions (rash, itching, swelling), and liver problems (yellowing of skin/eyes, dark urine). In rare cases, it can affect blood cell counts. Contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for IGNALIS M 50/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use IGNALIS M 50/500MG TABLET 10'S if you are allergic to it.

Dosage of IGNALIS M 50/500MG TABLET 10'SArrow

  • The recommended dosage of IGNALIS M 50/500MG TABLET 10'S is individualized and depends on several factors, including your blood glucose levels, your response to treatment, and other medications you may be taking. Your physician will determine the appropriate dosage for you. Typically, it is administered once or twice daily with meals to minimize gastrointestinal discomfort. The starting dose is usually low and gradually increased as needed to achieve optimal glycemic control.
  • It is crucial to adhere strictly to your doctor's instructions regarding the dosage and timing of IGNALIS M 50/500MG TABLET 10'S. Do not exceed the prescribed dose or change the dosage regimen without consulting your healthcare provider. Regular monitoring of your blood glucose levels is essential to assess the effectiveness of the medication and to make any necessary dosage adjustments. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • If you have kidney or liver problems, your doctor may need to adjust your dosage of IGNALIS M 50/500MG TABLET 10'S. Similarly, caution is advised when using this medication in elderly patients, as they may be more susceptible to side effects. It's important to have regular check-ups with your doctor, including blood tests, to monitor your kidney and liver function while you're taking this medication.
  • Take 'IGNALIS M 50/500MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of IGNALIS M 50/500MG TABLET 10'S?Arrow

  • If you miss a dose of IGNALIS M 50/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store IGNALIS M 50/500MG TABLET 10'S?Arrow

  • Keep IGNALIS M 50/500MG TAB 1X10 away from the reach of children and pets.
  • Store IGNALIS M 50/500MG TAB 1X10 at room temperature.

Benefits of IGNALIS M 50/500MG TABLET 10'SArrow

  • IGNALIS M 50/500MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It effectively controls blood sugar levels and improves the body's response to insulin. This medication helps prevent serious complications of diabetes, such as kidney damage, nerve problems, loss of limbs, and sexual dysfunction, and may also reduce the risk of heart attack or stroke.
  • By improving glycemic control, IGNALIS M reduces the risk of microvascular complications like diabetic retinopathy (eye damage), nephropathy (kidney damage), and neuropathy (nerve damage). Better blood sugar management protects the small blood vessels and nerves, preventing or delaying the onset and progression of these debilitating conditions.
  • IGNALIS M enhances insulin sensitivity, enabling the body to use insulin more efficiently. This is crucial for individuals with insulin resistance, a common characteristic of type 2 diabetes. Increased insulin sensitivity helps lower blood sugar levels and reduces the need for higher doses of insulin or other medications.
  • Metformin, one of the active ingredients in IGNALIS M, has been shown to have potential cardiovascular benefits. It may help improve cholesterol levels and reduce the risk of heart disease, a major concern for people with diabetes. Furthermore, good control of blood sugar is directly associated with reduced risk of cardiovascular events.
  • IGNALIS M promotes overall well-being by managing blood sugar levels, which can reduce symptoms like excessive thirst, frequent urination, and fatigue. By stabilizing energy levels and reducing the burden of diabetic symptoms, patients can experience an improved quality of life.
  • The combination of two different oral antidiabetic agents in IGNALIS M can lead to better blood sugar control than using either medication alone. This synergistic effect simplifies the treatment regimen and improves patient compliance, as it reduces the number of pills required daily.
  • IGNALIS M helps maintain stable blood sugar levels throughout the day, preventing drastic spikes and drops. This stability is essential for managing diabetes effectively and avoiding complications. Consistently maintaining a normal blood sugar range reduces the risk of long-term health issues associated with diabetes.
  • This medication is used in conjunction with a healthy diet and regular exercise to achieve optimal blood sugar control. It supports lifestyle modifications and helps patients maximize the benefits of their dietary and physical activity efforts.
  • IGNALIS M provides a convenient and effective way to manage type 2 diabetes, helping patients lead healthier and more fulfilling lives by minimizing the impact of diabetes on their daily routines and long-term health.

How to use IGNALIS M 50/500MG TABLET 10'SArrow

  • IGNALIS M 50/500MG TABLET 10'S should be taken orally, preferably with or immediately after a meal, to minimize the risk of stomach upset. The dosage is usually prescribed by your doctor, taking into account your individual condition, blood glucose levels, and response to treatment. It is crucial to adhere to the prescribed dosage and timing.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this could affect how the medication is released into your system. If you have difficulty swallowing tablets, consult your doctor or pharmacist for alternative formulations or strategies.
  • Consistency is key for effective management of your blood sugar levels. Try to take IGNALIS M 50/500MG TABLET 10'S at the same time each day to help you remember. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It is important to continue following your doctor's recommendations regarding diet and exercise while taking this medication. IGNALIS M 50/500MG TABLET 10'S works best when combined with a healthy lifestyle. Regularly monitor your blood glucose levels as directed by your healthcare provider, and inform them of any unusual symptoms or side effects you experience.
  • Long-term use of IGNALIS M 50/500MG TABLET 10'S requires regular check-ups with your doctor to monitor kidney function, liver function, and blood counts. Follow your doctor's instructions carefully, and do not stop taking the medication without consulting them first. Suddenly stopping the medication can lead to fluctuations in blood sugar levels and potential health complications.

Quick Tips for IGNALIS M 50/500MG TABLET 10'SArrow

  • Take IGNALIS M 50/500MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medicine without consulting them, as this can affect your blood sugar control.
  • IGNALIS M 50/500MG TABLET 10'S is typically taken with meals to minimize gastrointestinal side effects. Try to take it at the same time each day to maintain a consistent level of medication in your body and improve adherence.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider while taking IGNALIS M 50/500MG TABLET 10'S. Keep a record of your readings and share them with your doctor during your appointments. This helps in adjusting the dosage if needed.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or juice, with you at all times to treat hypoglycemia promptly. Inform your family and friends about how to recognize and treat hypoglycemia.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they can interact with IGNALIS M 50/500MG TABLET 10'S. Pay special attention to medications that can affect blood sugar levels, such as corticosteroids or diuretics. Also, maintain a healthy lifestyle by following a balanced diet and exercising regularly to maximize the benefits of the medicine and improve your overall health.
  • If you experience persistent side effects such as nausea, vomiting, diarrhea, or abdominal pain, consult your doctor. Do not self-treat. Your doctor may adjust your dosage or recommend alternative medications.
  • Store IGNALIS M 50/500MG TABLET 10'S at room temperature, away from moisture and direct sunlight. Keep it out of reach of children. Check the expiration date before taking the medicine and dispose of any expired tablets properly.
  • During periods of stress, illness, or surgery, your blood sugar levels may fluctuate. Monitor your blood sugar more frequently during these times and consult your doctor for dosage adjustments if necessary. Never adjust the dosage on your own.

Food Interactions with IGNALIS M 50/500MG TABLET 10'SArrow

  • Avoid excessive alcohol consumption while taking IGNALIS M 50/500MG TABLET 10'S as it may increase the risk of lactic acidosis. Additionally, grapefruit products may interact with sitagliptin, so it's advisable to limit their consumption.

FAQs

What is Ignalis M 50/500mg Tablet 10's and what is it used for?Arrow

Ignalis M 50/500mg Tablet 10's is a combination of two medicines: vildagliptin and metformin. It is used to treat type 2 diabetes mellitus when diet and exercise alone do not provide adequate blood sugar control.

How does Ignalis M 50/500mg Tablet 10's work?Arrow

Vildagliptin works by inhibiting the DPP-4 enzyme, which increases insulin secretion and reduces glucose production. Metformin works by decreasing the amount of glucose produced by the liver and improving insulin sensitivity.

What are the common side effects of Ignalis M 50/500mg Tablet 10's?Arrow

Common side effects of Ignalis M 50/500mg Tablet 10's include nausea, vomiting, diarrhea, abdominal pain, and headache.

Is Ignalis M 50/500mg Tablet 10's safe for patients with kidney disease?Arrow

Ignalis M 50/500mg Tablet 10's should be used with caution in patients with kidney disease. The dosage may need to be adjusted based on kidney function. It is not recommended for patients with severe kidney disease.

Does Ignalis M 50/500mg Tablet 10's cause weight gain?Arrow

Ignalis M 50/500mg Tablet 10's is not typically associated with weight gain. In some patients, it may lead to weight loss.

Is it safe to take Ignalis M 50/500mg Tablet 10's during pregnancy?Arrow

The safety of Ignalis M 50/500mg Tablet 10's during pregnancy has not been established. It should only be used if the potential benefit justifies the risk to the fetus. Consult your doctor.

How should I store Ignalis M 50/500mg Tablet 10's?Arrow

Store Ignalis M 50/500mg Tablet 10's at room temperature, away from direct sunlight and heat. Keep out of reach of children and pets.

Can Ignalis M 50/500mg Tablet 10's be taken with or without food?Arrow

It is recommended to take Ignalis M 50/500mg Tablet 10's with food to avoid stomach upset.

What happens if I miss a dose of Ignalis M 50/500mg Tablet 10's?Arrow

If you miss a dose of Ignalis M 50/500mg Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can I drink alcohol with Ignalis M 50/500mg Tablet 10's?Arrow

It is not recommended to drink alcohol with Ignalis M 50/500mg Tablet 10's, as it may increase the risk of lactic acidosis, a serious side effect.

Does Ignalis M 50/500mg Tablet 10's interact with other medications?Arrow

Ignalis M 50/500mg Tablet 10's can interact with certain medications, such as diuretics, corticosteroids, and thyroid hormones. Inform your doctor about all the medications you are taking.

Is Ignalis M 50/500mg Tablet 10's safe for children?Arrow

The safety and efficacy of Ignalis M 50/500mg Tablet 10's have not been established in children. Therefore, its use is not recommended in children.

What should I tell my doctor before starting Ignalis M 50/500mg Tablet 10's?Arrow

Before starting Ignalis M 50/500mg Tablet 10's, tell your doctor about all your medical conditions, allergies, and medications you are taking. In addition, let them know if you are pregnant or breastfeeding.

How long will I need to take Ignalis M 50/500mg Tablet 10's?Arrow

The duration for which you will need to take Ignalis M 50/500mg Tablet 10's will be determined by your doctor. It is usually recommended to take it long-term, as long as it is effective in controlling your blood sugar levels and you are not experiencing any significant side effects.

Is lifestyle change necessary with Ignalis M 50/500mg Tablet 10's?Arrow

Yes, it is important to maintain a healthy lifestyle while taking Ignalis M 50/500mg Tablet 10's. This includes eating a healthy diet, exercising regularly, and avoiding smoking and alcohol.

References

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Medicines.org.uk - This site may contain Summaries of Product Characteristics (SmPC) providing detailed information on pharmaceutical products. Look for products containing Metformin and/or Vildagliptin.

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DrugBank - Entry for Metformin. Comprehensive information on Metformin, including its mechanism of action, pharmacology, and therapeutic uses.

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DrugBank - Entry for Vildagliptin. Comprehensive information on Vildagliptin, including its mechanism of action, pharmacology, and therapeutic uses.

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FDA Drugs@FDA - Search for drug approvals by active ingredient (Metformin and Vildagliptin) to find approval information, labels, and reviews.

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European Medicines Agency (EMA) - Search for scientific information and regulatory details on medicines authorized in the European Union that contain Metformin and Vildagliptin.

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PubMed - Search for research articles on Metformin and Vildagliptin. Use search terms like "Metformin Vildagliptin combination" to find relevant studies.

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UpToDate - Clinical resource providing evidence-based information on various medical topics, including diabetes management with medications like Metformin and Vildagliptin (Subscription Required).

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INTAS PHARMACEUTICALS LIMITED

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