INTAGLIP M SR 1000 TABLET 10'S
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INTAGLIP M SR 1000 TABLET 10'S
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INTAGLIP M SR 1000 TABLET 10'S

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INTAGLIP M SR 1000 TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

95

₹80.75

15 % OFF

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Tablet

10

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About INTAGLIP M SR 1000 TABLET 10'S

  • INTAGLIP M SR 1000 is a combination medicine used to treat type 2 diabetes mellitus. It combines two antidiabetic medicines, Intagliptin and Metformin, to control high blood sugar levels in adults. This medication is typically prescribed when diet and exercise alone are not sufficient to manage blood glucose effectively. INTAGLIP M SR 1000 helps your body better utilize insulin, a natural substance that lowers blood sugar levels.
  • Intagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by increasing the release of insulin from the pancreas and decreasing the secretion of glucagon, a hormone that raises blood sugar. Metformin, on the other hand, is a biguanide that reduces glucose production in the liver and improves insulin sensitivity in the body's tissues, allowing for better glucose uptake. The SR in the name stands for Sustained Release, which means the Metformin is released slowly into the body, reducing the risk of side effects.
  • By taking INTAGLIP M SR 1000 as directed by your doctor, you can effectively manage your blood sugar levels and reduce the risk of serious complications associated with diabetes, such as kidney damage, nerve problems, vision loss, and heart disease. It's crucial to maintain a healthy lifestyle, including a balanced diet and regular exercise, while taking this medication to maximize its benefits. Always follow your doctor's instructions regarding dosage and timing. Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. If you experience any persistent or severe side effects, consult your healthcare provider immediately.
  • INTAGLIP M SR 1000 is usually taken once or twice daily with meals to minimize gastrointestinal discomfort. Regular monitoring of blood sugar levels is essential to ensure the medication is working effectively and to adjust the dosage if needed. Inform your doctor about any other medications you are taking, as drug interactions can occur. This medicine is not recommended for people with severe kidney or liver problems. Always consult with your doctor or pharmacist for any questions.

Uses of INTAGLIP M SR 1000 TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Increasing insulin sensitivity
  • Managing insulin resistance in Polycystic Ovary Syndrome (PCOS) (off-label use)
  • Management of metabolic syndrome (off-label use)

How INTAGLIP M SR 1000 TABLET 10'S Works

  • INTAGLIP M SR 1000 Tablet is a combination medicine that effectively tackles high blood sugar levels in individuals with type 2 diabetes. It harnesses the power of two active ingredients: Sitagliptin and Metformin.
  • Sitagliptin belongs to a class of drugs known as DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by increasing the amount of incretin hormones released by your gut after a meal. These incretin hormones play a crucial role in regulating blood sugar levels. Sitagliptin helps to block the action of the DPP-4 enzyme, which normally breaks down incretin hormones. By inhibiting DPP-4, Sitagliptin prolongs the activity of incretin hormones. This leads to an increase in insulin release from the pancreas when blood sugar is high, and a decrease in glucagon secretion (a hormone that raises blood sugar) from the pancreas. Ultimately, Sitagliptin helps to lower blood sugar levels after meals and throughout the day.
  • Metformin, on the other hand, is a biguanide. It primarily works in the liver to reduce glucose production. Specifically, Metformin decreases the amount of glucose the liver releases into the bloodstream. It also improves the body's sensitivity to insulin, meaning that the body can use insulin more effectively to lower blood sugar. Furthermore, Metformin slows down the absorption of glucose from the intestines into the bloodstream after you eat. This synergistic action of Sitagliptin and Metformin provides comprehensive control over blood sugar levels in patients with type 2 diabetes.
  • In summary, INTAGLIP M SR 1000 Tablet works through a dual mechanism: Sitagliptin enhances insulin release and reduces glucagon secretion by prolonging incretin hormone activity, while Metformin reduces glucose production in the liver, improves insulin sensitivity, and slows down glucose absorption from the intestine. This combined effect helps to maintain healthy blood sugar levels.

Side Effects of INTAGLIP M SR 1000 TABLET 10'SArrow

Common side effects of INTAGLIP M SR 1000 Tablet may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Less common but potentially serious side effects can include lactic acidosis (symptoms may include feeling cold, dizzy, lightheaded, tired, or weak), pancreatitis (severe stomach pain radiating to the back), and allergic reactions (rash, itching, swelling). Some patients might experience headache, upper respiratory tract infection, or joint pain. If you experience any persistent or severe side effects, discontinue use and consult your doctor immediately.

Safety Advice for INTAGLIP M SR 1000 TABLET 10'SArrow

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Allergies

Allergies

Do not use INTAGLIP M SR 1000 TABLET if you are allergic to it.

Dosage of INTAGLIP M SR 1000 TABLET 10'SArrow

  • The recommended dosage of INTAGLIP M SR 1000 Tablet 10'S is individualized and depends on several factors, including your blood glucose levels, overall health, and response to treatment. Your doctor will determine the appropriate dose for you. Typically, it is taken once or twice daily with meals to help reduce gastrointestinal side effects. The 'SR' in the name indicates 'Sustained Release,' meaning the medication is released slowly into your system, providing a more consistent effect over time. It is crucial to swallow the tablet whole and not to crush, chew, or break it, as this can affect the way the medication is released and may lead to adverse effects.
  • The starting dose is usually low, and your doctor may gradually increase it to achieve optimal blood glucose control. It is essential to monitor your blood glucose levels regularly as directed by your healthcare provider, especially when you start taking INTAGLIP M SR 1000 Tablet 10'S or when your dosage is adjusted. This will help determine how well the medication is working and whether any changes are needed. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Adhering to your doctor's prescribed dosage and schedule is vital for effectively managing your blood sugar levels and preventing complications associated with diabetes. Consistent use, combined with a healthy diet and regular exercise, will maximize the benefits of INTAGLIP M SR 1000 Tablet 10'S. Always inform your doctor about any other medications, supplements, or herbal products you are taking to avoid potential drug interactions. Report any unusual side effects or concerns to your doctor promptly.
  • Take 'INTAGLIP M SR 1000 TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of INTAGLIP M SR 1000 TABLET 10'S?Arrow

  • If you miss a dose of INTAGLIP M SR 1000 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store INTAGLIP M SR 1000 TABLET 10'S?Arrow

  • Keep INTAGLIP M SR 50/1000MG TAB 1X10 away from the reach of children and pets.
  • Store INTAGLIP M SR 50/1000MG TAB 1X10 at room temperature.

Benefits of INTAGLIP M SR 1000 TABLET 10'SArrow

  • INTAGLIP M SR 1000 TABLET 10'S offers a dual-action approach to managing type 2 diabetes by combining a DPP-4 inhibitor (Sitagliptin) and a biguanide (Metformin). This synergistic effect helps to regulate blood sugar levels more effectively than either medication alone. Sitagliptin enhances the body's own ability to lower blood sugar by increasing the release of insulin and decreasing the secretion of glucagon, a hormone that raises blood sugar. Metformin, on the other hand, reduces glucose production in the liver, improves insulin sensitivity, and slows down the absorption of glucose from the intestines.
  • One of the primary benefits of INTAGLIP M SR 1000 is its ability to provide sustained glycemic control. The 'SR' in the name stands for sustained release, meaning that Metformin is released slowly into the body over an extended period. This helps to maintain stable blood sugar levels throughout the day and night, reducing the risk of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). Stable blood sugar levels are crucial for preventing long-term complications of diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • INTAGLIP M SR 1000 can also contribute to weight management in some individuals. While not specifically a weight loss drug, Metformin has been shown to have a modest weight-reducing effect or at least prevent weight gain, which is often a concern with other diabetes medications. This is particularly beneficial for overweight or obese individuals with type 2 diabetes, as weight loss can improve insulin sensitivity and overall metabolic health.
  • Beyond glycemic control and potential weight benefits, INTAGLIP M SR 1000 offers the convenience of a single tablet formulation. Combining two medications into one pill simplifies the treatment regimen, making it easier for patients to adhere to their prescribed medication schedule. Improved adherence leads to better blood sugar control and a reduced risk of diabetes-related complications. The once- or twice-daily dosing schedule of INTAGLIP M SR further enhances convenience.
  • Furthermore, INTAGLIP M SR 1000 is generally well-tolerated, with a relatively low risk of side effects compared to some other diabetes medications. Common side effects, such as gastrointestinal upset, are usually mild and temporary. Serious side effects are rare. The combination of Sitagliptin and Metformin in INTAGLIP M SR is less likely to cause hypoglycemia (low blood sugar) compared to some other diabetes medications, especially when used without other blood-sugar-lowering drugs.
  • INTAGLIP M SR 1000 also provides cardiovascular benefits. Studies have shown that Metformin, a key component of INTAGLIP M SR 1000, may reduce the risk of cardiovascular events, such as heart attack and stroke, in people with type 2 diabetes. This is particularly important, as cardiovascular disease is a leading cause of death in people with diabetes. By improving blood sugar control and potentially reducing cardiovascular risk factors, INTAGLIP M SR 1000 can contribute to overall health and well-being.
  • Finally, INTAGLIP M SR 1000 can improve insulin sensitivity, which is the body's ability to use insulin effectively. In type 2 diabetes, the body becomes resistant to insulin, leading to high blood sugar levels. By improving insulin sensitivity, INTAGLIP M SR 1000 helps the body use insulin more efficiently, resulting in better blood sugar control. This can also reduce the need for higher doses of insulin or other diabetes medications.

How to use INTAGLIP M SR 1000 TABLET 10'SArrow

  • INTAGLIP M SR 1000 Tablet is designed for oral administration and should be taken exactly as prescribed by your doctor. Typically, it is taken once or twice daily with meals to minimize the risk of stomach upset. It is crucial to swallow the tablet whole with a full glass of water, without crushing, chewing, or breaking it, as this could affect the modified-release properties of the medication and alter its effectiveness.
  • Adhere strictly to the prescribed dosage and timing. Do not alter the dosage or discontinue the medication without consulting your healthcare provider, even if you feel better. Consistent daily intake at the same time(s) is recommended to maintain stable blood glucose levels. Missing doses can lead to fluctuations in your blood sugar.
  • Before starting INTAGLIP M SR 1000, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart conditions, or allergies. Also, disclose any other medications, supplements, or herbal products you are currently taking to avoid potential drug interactions. Regular monitoring of your blood sugar levels is essential while on this medication to assess its effectiveness and adjust the dosage if necessary. Your doctor may also recommend periodic kidney and liver function tests.
  • It's important to maintain a healthy lifestyle while taking INTAGLIP M SR 1000. This includes following a balanced diet, engaging in regular physical activity, and managing stress. These lifestyle modifications can significantly improve blood sugar control and overall health. Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, and confusion, and know how to manage it. Conversely, also be aware of symptoms of high blood sugar(hyperglycemia), increased thirst and frequent urination. In case of any side effects or concerns, consult your doctor promptly.
  • Store INTAGLIP M SR 1000 tablets in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children. If you experience any severe or persistent side effects, such as severe abdominal pain, nausea, or vomiting, seek immediate medical attention.

Quick Tips for INTAGLIP M SR 1000 TABLET 10'SArrow

  • Take INTAGLIP M SR 1000 Tablet as prescribed by your doctor. It's crucial to follow the dosage and timing instructions provided to maintain consistent blood sugar control. Typically, it is taken once or twice daily with meals.
  • Consistency is key. Try to take INTAGLIP M SR 1000 Tablet at the same time(s) each day to help you remember and to keep a steady level of medication in your bloodstream. This maximizes its effectiveness in managing your blood sugar levels.
  • Monitor your blood sugar regularly. Work with your healthcare provider to establish a blood sugar monitoring routine. Regular monitoring helps you understand how INTAGLIP M SR 1000 Tablet and other factors like diet and exercise are affecting your glucose levels. Share these results with your doctor.
  • Be mindful of potential side effects. Common side effects may include nausea, diarrhea, or stomach upset. If these or any other side effects become bothersome or persistent, contact your doctor immediately. Do not stop taking the medication without consulting your healthcare provider.
  • Combine INTAGLIP M SR 1000 Tablet with a healthy lifestyle. This medication works best when combined with a balanced diet and regular physical activity. Focus on incorporating whole grains, lean proteins, fruits, and vegetables into your meals. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Consult with a registered dietitian or certified personal trainer for personalized guidance.

Food Interactions with INTAGLIP M SR 1000 TABLET 10'SArrow

  • INTAGLIP M SR 1000 TABLET 10'S should be taken with food to help reduce stomach upset. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a serious side effect.
  • The absorption of INTAGLIP M SR 1000 TABLET 10'S may be affected by the type and timing of food intake. Follow your doctor's instructions regarding when and how to take this medicine with meals.

FAQs

What is INTAGLIP M SR 1000 TABLET used for?Arrow

INTAGLIP M SR 1000 TABLET is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

What are the active ingredients in INTAGLIP M SR 1000 TABLET?Arrow

INTAGLIP M SR 1000 TABLET contains two active ingredients: Sitagliptin and Metformin.

How does INTAGLIP M SR 1000 TABLET work?Arrow

Sitagliptin belongs to a class of drugs called DPP-4 inhibitors, which works by increasing insulin secretion and decreasing glucagon secretion. Metformin belongs to a class of drugs called biguanides, which works by decreasing the amount of glucose produced by the liver.

What are the common side effects of INTAGLIP M SR 1000 TABLET?Arrow

Common side effects of INTAGLIP M SR 1000 TABLET include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is INTAGLIP M SR 1000 TABLET safe for people with kidney problems?Arrow

INTAGLIP M SR 1000 TABLET is not recommended for people with kidney problems. Talk to your doctor before taking this medication if you have any kidney issues.

How to store INTAGLIP M SR 1000 TABLET?Arrow

Store INTAGLIP M SR 1000 TABLET at room temperature, away from heat and moisture.

Should INTAGLIP M SR 1000 TABLET be taken with food?Arrow

It is recommended to take INTAGLIP M SR 1000 TABLET with food to reduce the chance of stomach upset.

What happens if I miss a dose of INTAGLIP M SR 1000 TABLET?Arrow

If you miss a dose of INTAGLIP M SR 1000 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can INTAGLIP M SR 1000 TABLET interact with other medications?Arrow

INTAGLIP M SR 1000 TABLET can interact with certain other medications. Tell your doctor about all your medications before taking this medicine.

What are the symptoms of an overdose of INTAGLIP M SR 1000 TABLET?Arrow

Symptoms of an overdose of INTAGLIP M SR 1000 TABLET include nausea, vomiting, diarrhea, abdominal pain, weakness, and dizziness.

Is INTAGLIP M SR 1000 TABLET safe for pregnant women?Arrow

The safety of INTAGLIP M SR 1000 TABLET for pregnant women has not been established. Talk to your doctor before taking this medication if you are pregnant or planning to become pregnant.

Is INTAGLIP M SR 1000 TABLET safe for breastfeeding women?Arrow

It is not known whether INTAGLIP M SR 1000 TABLET passes into breast milk. Talk to your doctor before taking this medication if you are breastfeeding.

Does INTAGLIP M SR 1000 TABLET cause weight gain?Arrow

INTAGLIP M SR 1000 TABLET does not typically cause weight gain. However, some people may experience it.

Can I drink alcohol while taking INTAGLIP M SR 1000 TABLET?Arrow

It is not recommended to drink alcohol while taking INTAGLIP M SR 1000 TABLET as it can lower blood sugar levels and cause other side effects.

Are there alternative medications to INTAGLIP M SR 1000 TABLET?Arrow

Yes, there are several alternatives available to INTAGLIP M SR 1000 TABLET. Talk to your doctor to find the best option for you.

References

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Efficacy and Safety of Vildagliptin-Metformin Combination Therapy in Indian Patients with Type 2 Diabetes Mellitus: A Subgroup Analysis of Real-World Data

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Vildagliptin Drug Record (DrugBank)

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FDA prescribing information for Vildagliptin (mentions use with metformin)

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European Medicines Agency (EMA) assessment report for Galvus (Vildagliptin)

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Systematic review of vildagliptin efficacy and safety

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European Medicines Agency (EMA) assessment report for Glucophage (Metformin)

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FDA prescribing information for Metformin Hydrochloride

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Very cheap, helpful, friendly service

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Reviewed on 10-02-2023

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All drugs available good service

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Reviewed on 23-01-2024

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(5/5)


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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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