JUSTOZA GM 1 FORTE TABLET 10'S
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JUSTOZA GM 1 FORTE TABLET 10'S
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JUSTOZA GM 1 FORTE TABLET 10'S

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JUSTOZA GM 1 FORTE TABLET 10'S

By MANKIND PHARMA LIMITED

MRP

125

₹106.25

15 % OFF

₹10.63 Only /

Tablet

10

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About JUSTOZA GM 1 FORTE TABLET 10'S

  • JUSTOZA GM 1 FORTE TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when combined with diet and exercise. This medication works by increasing insulin secretion from the pancreas, decreasing glucose production in the liver, and improving the body's sensitivity to insulin.
  • The tablet contains a combination of three active ingredients: Glimepiride, Metformin, and Voglibose. Glimepiride is a sulfonylurea that stimulates the pancreas to release more insulin. Metformin is a biguanide that reduces glucose production in the liver and improves insulin sensitivity. Voglibose is an alpha-glucosidase inhibitor that slows down the absorption of carbohydrates from the intestine, preventing rapid spikes in blood sugar levels after meals.
  • JUSTOZA GM 1 FORTE is typically taken once or twice daily, as prescribed by your doctor. It is important to take the medicine at the same time each day to maintain consistent blood sugar levels. Common side effects may include nausea, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). It's crucial to monitor blood sugar levels regularly and inform your doctor of any unusual symptoms. This medication is a valuable tool in managing type 2 diabetes when used as part of a comprehensive treatment plan that includes lifestyle modifications.

Uses of JUSTOZA GM 1 FORTE TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Increasing insulin sensitivity
  • Reducing post-meal blood sugar levels
  • May be used in combination with other diabetes medications

How JUSTOZA GM 1 FORTE TABLET 10'S Works

  • JUSTOZA GM 1 FORTE TABLET is a combination medication designed to manage type 2 diabetes effectively. It comprises three active ingredients: Glimepiride, Metformin, and Pioglitazone, each working through different mechanisms to lower blood glucose levels.
  • Glimepiride belongs to the sulfonylurea class of drugs. It stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose from the blood enter cells, where it is used for energy. By increasing insulin secretion, Glimepiride helps lower blood sugar levels, particularly after meals.
  • Metformin is a biguanide that works primarily by decreasing glucose production in the liver. It reduces the amount of glucose released into the bloodstream. Metformin also improves the body's sensitivity to insulin, allowing cells to use glucose more effectively. Additionally, it slows down the absorption of glucose from the intestines after food intake, further contributing to blood sugar control. This multi-pronged approach makes Metformin a cornerstone in managing type 2 diabetes.
  • Pioglitazone is a thiazolidinedione (TZD) that enhances insulin sensitivity in peripheral tissues such as muscles and fat. It works by activating PPARγ (peroxisome proliferator-activated receptor gamma), a nuclear receptor that regulates genes involved in glucose and lipid metabolism. By improving insulin sensitivity, Pioglitazone helps cells take up and utilize glucose more efficiently, thereby lowering blood sugar levels. Pioglitazone also helps to reduce insulin resistance, a common problem in type 2 diabetes.
  • In summary, JUSTOZA GM 1 FORTE TABLET combines the insulin-releasing action of Glimepiride, the glucose production-reducing and insulin-sensitizing effects of Metformin, and the insulin-sensitizing action of Pioglitazone. This synergistic combination provides comprehensive blood sugar control, helping individuals with type 2 diabetes achieve and maintain their target glucose levels. This medication should be taken as prescribed by your healthcare provider, along with a healthy diet and regular exercise, to maximize its benefits and minimize potential side effects.

Side Effects of JUSTOZA GM 1 FORTE TABLET 10'SArrow

Possible side effects of JUSTOZA GM 1 FORTE Tablet may include:\n\n* **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness.\n* **Uncommon:** Allergic reactions (skin rash, itching, hives), edema (swelling), weight gain, constipation, heartburn, abnormal liver function tests, weakness, fatigue, blurred vision, tremors.\n* **Rare:** Serious allergic reactions (anaphylaxis), severe hypoglycemia, liver problems (jaundice, hepatitis), blood disorders (anemia, leukopenia, thrombocytopenia), pancreatitis, muscle pain or weakness (myopathy), lactic acidosis (a build-up of lactic acid in the body).\n\n**Important:** This is not an exhaustive list. If you experience any unusual or severe side effects, stop taking JUSTOZA GM 1 FORTE Tablet and consult your doctor immediately.

Safety Advice for JUSTOZA GM 1 FORTE TABLET 10'SArrow

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Allergies

Allergies

Consult your doctor if you are allergic to this medicine.

Dosage of JUSTOZA GM 1 FORTE TABLET 10'SArrow

  • The dosage of 'JUSTOZA GM 1 FORTE TABLET 10'S' is highly individualized and should be determined by your physician based on your specific needs, medical condition, and response to treatment. It is typically taken orally, once or twice daily, preferably with meals to minimize gastrointestinal discomfort. The initial recommended dose is usually low, and your doctor may gradually increase it to achieve optimal blood glucose control. The maximum recommended daily dose should not be exceeded.
  • Several factors influence the ideal dosage, including your blood glucose levels, HbA1c (a measure of long-term blood sugar control), kidney function, liver function, and other medications you may be taking. Regular monitoring of these parameters is crucial to ensure the medication is effective and safe for you. Your doctor will adjust the dosage accordingly to maintain your blood sugar within the target range and minimize the risk of side effects such as hypoglycemia (low blood sugar).
  • It's essential to adhere to the prescribed dosage and timing of 'JUSTOZA GM 1 FORTE TABLET 10'S'. Missing doses or taking the medication at inconsistent times can affect its effectiveness. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have any questions or concerns about your dosage, contact your doctor or pharmacist for clarification. Remember that 'JUSTOZA GM 1 FORTE TABLET 10'S' is most effective when combined with a healthy diet and regular exercise.
  • Take 'JUSTOZA GM 1 FORTE TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of JUSTOZA GM 1 FORTE TABLET 10'S?Arrow

  • If you miss a dose of JUSTOZA GM 1 FORTE TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store JUSTOZA GM 1 FORTE TABLET 10'S?Arrow

  • Keep JUSTOZA GM 1 FORTE TAB 1X10 away from the reach of children and pets.
  • Store JUSTOZA GM 1 FORTE TAB 1X10 at room temperature.

Benefits of JUSTOZA GM 1 FORTE TABLET 10'SArrow

  • JUSTOZA GM 1 FORTE TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise alone are not sufficient to control blood sugar levels effectively. It combines three active ingredients: Glimepiride, Metformin, and Voglibose, each working through different mechanisms to lower blood glucose and improve glycemic control.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose get from the blood into your cells, where it’s used for energy. By increasing insulin secretion, Glimepiride helps lower blood sugar levels, particularly after meals. This is especially beneficial for managing postprandial hyperglycemia (high blood sugar after eating).
  • Metformin, a biguanide, works primarily by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. It reduces the amount of glucose released into the bloodstream and helps cells respond better to insulin, allowing them to take up glucose more efficiently. Metformin also has the added benefit of not typically causing weight gain and may even promote modest weight loss in some individuals, unlike some other diabetes medications.
  • Voglibose, an alpha-glucosidase inhibitor, slows down the absorption of carbohydrates from the intestine into the bloodstream. It inhibits the enzymes that break down complex carbohydrates into simpler sugars, thus reducing the rapid rise in blood sugar levels after meals. This is particularly helpful in controlling postprandial hyperglycemia and maintaining more stable blood sugar levels throughout the day.
  • By combining these three medications, JUSTOZA GM 1 FORTE TABLET 10'S offers a comprehensive approach to managing type 2 diabetes. It addresses multiple aspects of the disease, including insulin secretion, insulin sensitivity, and carbohydrate absorption. This multi-pronged approach can lead to better overall glycemic control and reduce the risk of long-term complications associated with diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • The use of JUSTOZA GM 1 FORTE TABLET 10'S can also result in improved HbA1c levels, which is a measure of average blood sugar control over a period of 2-3 months. Lowering HbA1c levels is crucial in preventing or delaying the progression of diabetic complications. Regular monitoring of blood sugar levels, adherence to a healthy diet and exercise regimen, and regular check-ups with a healthcare provider are essential for maximizing the benefits of this medication and managing diabetes effectively.

How to use JUSTOZA GM 1 FORTE TABLET 10'SArrow

  • JUSTOZA GM 1 FORTE TABLET 10'S should be taken orally, usually once daily, preferably with your first main meal to minimize gastrointestinal discomfort. Always follow your doctor's prescription regarding dosage and timing. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water.
  • Consistency is key for optimal blood sugar control. Try to take JUSTOZA GM 1 FORTE TABLET 10'S at the same time each day. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking JUSTOZA GM 1 FORTE TABLET 10'S, it's crucial to monitor your blood sugar levels regularly as directed by your physician or diabetes educator. This will help assess how well the medication is working and whether dosage adjustments are needed. Inform your doctor of all other medications, including over-the-counter drugs and herbal supplements, you are taking, as they may interact with JUSTOZA GM 1 FORTE TABLET 10'S.
  • Maintain a healthy lifestyle by following a balanced diet, engaging in regular physical activity, and managing stress. These factors can significantly impact blood sugar control and the effectiveness of JUSTOZA GM 1 FORTE TABLET 10'S. Attend all scheduled appointments with your doctor and other healthcare providers to discuss your progress and address any concerns you may have. Long-term use requires consistent follow-ups and monitoring.
  • Be aware of the signs and symptoms of hypoglycemia (low blood sugar), such as sweating, shaking, dizziness, and confusion. If you experience these symptoms, consume a fast-acting source of sugar (e.g., glucose tablets, fruit juice, or hard candy) and seek medical attention immediately if symptoms persist or worsen. Similarly, be vigilant for symptoms of hyperglycemia (high blood sugar), such as increased thirst, frequent urination, and blurred vision, and contact your doctor if they occur. Report any unusual side effects or adverse reactions to your doctor promptly.

Quick Tips for JUSTOZA GM 1 FORTE TABLET 10'SArrow

  • Take JUSTOZA GM 1 FORTE TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistent adherence to the prescribed regimen is crucial for optimal blood sugar control and minimizing potential side effects.
  • Monitor your blood glucose levels regularly, as advised by your healthcare provider, while taking JUSTOZA GM 1 FORTE TABLET 10'S. Keep a log of your readings to track your progress and share it with your doctor during check-ups. This helps in adjusting the medication dosage if needed and ensures effective diabetes management.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting JUSTOZA GM 1 FORTE TABLET 10'S. Certain medications can interact with this medicine, potentially affecting its efficacy or increasing the risk of side effects. A complete medication history ensures your doctor can make informed decisions about your treatment plan.
  • Be aware of the symptoms of hypoglycemia (low blood sugar) while taking JUSTOZA GM 1 FORTE TABLET 10'S, such as sweating, dizziness, rapid heartbeat, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times to quickly raise your blood sugar levels if hypoglycemia occurs. Consult your doctor to understand how to manage hypoglycemic episodes effectively.
  • Follow a balanced diet and exercise regularly while taking JUSTOZA GM 1 FORTE TABLET 10'S. A healthy lifestyle, including proper nutrition and physical activity, complements the medication's effects and helps improve overall blood sugar control. Consult a registered dietitian or certified diabetes educator for personalized guidance on diet and exercise plans suitable for your condition.

Food Interactions with JUSTOZA GM 1 FORTE TABLET 10'SArrow

  • There is no specific information available on the interaction of JUSTOZA GM 1 FORTE TABLET 10'S with food. Generally, it is recommended to take this medication as directed by your doctor, with or without food. Follow your doctor's instructions regarding the timing and manner of taking the medicine.

FAQs

What is Justoza GM 1 Forte Tablet 10'S?Arrow

Justoza GM 1 Forte Tablet 10'S is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise are not sufficient to control blood sugar levels adequately.

What is Justoza GM 1 Forte Tablet 10'S used for?Arrow

Justoza GM 1 Forte Tablet 10'S is used to control high blood sugar levels in individuals with type 2 diabetes mellitus.

How does Justoza GM 1 Forte Tablet 10'S work?Arrow

Justoza GM 1 Forte Tablet 10'S is a combination of three medicines: Glimepiride, Metformin and Pioglitazone. Glimepiride works by increasing the release of insulin from the pancreas, Metformin works by decreasing glucose production in the liver and improving insulin sensitivity, and Pioglitazone works by increasing the body's sensitivity to insulin.

What are the common side effects of Justoza GM 1 Forte Tablet 10'S?Arrow

Common side effects of Justoza GM 1 Forte Tablet 10'S include nausea, vomiting, diarrhea, abdominal pain, and headache.

Can Justoza GM 1 Forte Tablet 10'S cause hypoglycemia (low blood sugar)?Arrow

Yes, Justoza GM 1 Forte Tablet 10'S can cause hypoglycemia, especially if you skip meals or engage in strenuous exercise.

Can I take Justoza GM 1 Forte Tablet 10'S during pregnancy?Arrow

Justoza GM 1 Forte Tablet 10'S is not recommended during pregnancy. Consult your doctor if you are pregnant or planning to become pregnant.

How should I store Justoza GM 1 Forte Tablet 10'S?Arrow

Store Justoza GM 1 Forte Tablet 10'S at room temperature, away from moisture and heat.

Should Justoza GM 1 Forte Tablet 10'S be taken with food?Arrow

Justoza GM 1 Forte Tablet 10'S is generally recommended to be taken with or after food to avoid stomach upset.

Can Justoza GM 1 Forte Tablet 10'S interact with other medications?Arrow

Yes, Justoza GM 1 Forte Tablet 10'S can interact with certain other medications. Inform your doctor about all the medicines you are taking.

What to do if I miss a dose of Justoza GM 1 Forte Tablet 10'S?Arrow

If you miss a dose of Justoza GM 1 Forte Tablet 10'S, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Is Justoza GM 1 Forte Tablet 10'S safe for people with kidney disease?Arrow

Justoza GM 1 Forte Tablet 10'S should be used with caution in people with kidney disease. Consult your doctor if you have kidney disease.

What lifestyle changes should I make while taking Justoza GM 1 Forte Tablet 10'S?Arrow

While taking Justoza GM 1 Forte Tablet 10'S, it is important to maintain a healthy diet, exercise regularly, and monitor your blood sugar levels regularly.

Can Justoza GM 1 Forte Tablet 10'S cause weight gain?Arrow

Yes, Justoza GM 1 Forte Tablet 10'S can cause weight gain, particularly due to the presence of Pioglitazone.

Are different brands of Metformin equally effective?Arrow

While different brands of Metformin contain the same active ingredient, their effectiveness and tolerability might vary in some cases. It's always best to consult a doctor.

What happens if I consume alcohol while taking Justoza GM 1 Forte Tablet 10'S?Arrow

Consuming alcohol while taking Justoza GM 1 Forte Tablet 10'S can increase the risk of hypoglycemia (low blood sugar) and may also worsen other side effects.

References

Book Icon

DrugBank: Gliclazide. Provides detailed information on Gliclazide, including its mechanism of action, pharmacokinetics, and therapeutic uses.

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FDA Label for Glimepiride. Official FDA label for Glimepiride, including dosage, warnings, and clinical studies.

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FDA Label for Metformin. Official FDA label for Metformin, including dosage, warnings, and clinical studies.

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Efficacy and safety of fixed-dose combination of metformin and gliclazide in type 2 diabetes mellitus inadequately controlled with metformin monotherapy: a randomized controlled trial. This study assesses the efficacy and safety of combining metformin and gliclazide.

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Glimepiride versus other second-generation sulfonylureas in the treatment of type 2 diabetes: a systematic review and meta-analysis. This meta-analysis compares the effectiveness of glimepiride with other sulfonylureas.

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UpToDate: Metformin drug information. Clinical information about Metformin, including its use in treating diabetes.

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JUSTOZA GM 1 FORTE TABLET 10'S

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