KHELLINEX TABLET 10'S

How KHELLINEX TABLET 10'S Works

• Khellinex Tablet 10's contains Khellin as its active ingredient, a naturally occurring furanochromone derivative. Khellin's primary mechanism of action involves its ability to act as a selective vasodilator, particularly affecting the coronary and renal blood vessels. This vasodilation is achieved through several pathways, contributing to its therapeutic effects.
• Firstly, Khellin inhibits phosphodiesterase enzymes, specifically PDE3 and PDE4. These enzymes are responsible for breaking down cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), respectively. By inhibiting these enzymes, Khellin increases intracellular levels of cAMP and cGMP in smooth muscle cells of blood vessels. Elevated cAMP levels lead to the activation of protein kinase A (PKA), which phosphorylates various target proteins involved in smooth muscle relaxation. Similarly, increased cGMP levels activate protein kinase G (PKG), further promoting vasodilation.
• Secondly, Khellin modulates calcium channel activity in smooth muscle cells. It inhibits the influx of calcium ions into these cells, which is crucial for muscle contraction. By reducing intracellular calcium concentrations, Khellin prevents the activation of the contractile machinery, resulting in smooth muscle relaxation and vasodilation. This effect is particularly significant in coronary arteries, where it helps to improve blood flow to the heart muscle.
• Thirdly, Khellin exhibits mild bronchodilatory effects. While its primary use is not as a bronchodilator, it can help relax bronchial smooth muscles, potentially alleviating bronchospasms and improving airflow in the lungs. This bronchodilatory action is also mediated by increased cAMP levels in bronchial smooth muscle cells.
• The overall effect of Khellin is to improve blood circulation, particularly to the heart and kidneys. This makes Khellinex Tablet 10's beneficial in conditions where improved blood flow is desired, such as in the management of angina pectoris (chest pain due to reduced blood flow to the heart) and certain renal disorders. The vasorelaxant and bronchodilatory properties of Khellin contribute to its therapeutic efficacy in these conditions. Always consult with a healthcare professional for appropriate use and dosage.
• Furthermore, Khellin's action on renal blood vessels promotes increased glomerular filtration rate (GFR), leading to enhanced kidney function and diuresis. This can aid in the management of conditions involving fluid retention and kidney-related issues. It's important to note that Khellin's effects are relatively mild, and it's often used as a complementary therapy rather than a primary treatment for severe conditions. The exact mechanism and extent of its effects can vary among individuals, highlighting the importance of personalized medical advice and monitoring.
• In summary, Khellinex Tablet 10's, through its active ingredient Khellin, works by dilating blood vessels (especially in the heart and kidneys), relaxing smooth muscles, and potentially improving airflow in the lungs. This multifaceted action is achieved through the inhibition of phosphodiesterase enzymes, modulation of calcium channel activity, and subsequent increase in intracellular cAMP and cGMP levels. These processes ultimately contribute to improved blood circulation, enhanced kidney function, and potential relief from bronchospasms.

Khellinex Tablet may cause side effects such as nausea, vomiting, loss of appetite, abdominal discomfort, and skin reactions like itching or rash. Less common side effects may include dizziness, headache, and liver problems. Rarely, it might cause photosensitivity (increased sensitivity to sunlight). Patients should consult their doctor if they experience any persistent or severe side effects.

• If you miss a dose of KHELLINEX TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep KHELLINEX TAB 1X10 away from the reach of children and pets.
• Store KHELLINEX TAB 1X10 at room temperature.

• Take Khellinex Tablet as prescribed by your doctor.
• Follow your doctor's instructions regarding dosage and duration. Do not exceed the recommended dose without consulting your healthcare provider.
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• Take Khellinex Tablet with food or after meals to avoid stomach upset.
• If you experience nausea or stomach discomfort while taking Khellinex, try taking it with a meal or snack. This can help to reduce gastrointestinal side effects and improve tolerability.
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• Maintain a consistent dosing schedule for optimal results.
• Try to take Khellinex Tablet at the same time each day to ensure a steady level of medication in your system. This can improve the effectiveness of the treatment.
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• Inform your doctor about all other medications and supplements you are taking.
• Khellinex can interact with other medications, potentially affecting their efficacy or increasing the risk of side effects. Disclose all prescription drugs, over-the-counter medications, and herbal supplements to your doctor.
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• Stay hydrated by drinking plenty of water throughout the day.
• Drinking enough water can help support kidney function and overall health while taking Khellinex Tablet. Aim for at least 8 glasses of water per day, unless otherwise instructed by your doctor.
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• While taking KHELLINEX TABLET 10'S, there are no specific restrictions on food. It can be taken with or without food. However, it is advisable to maintain a consistent dietary pattern.