LEEVARIN 15 TABLET 10'S

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• Methotrexate works by inhibiting dihydrofolate reductase, an enzyme crucial for cell function, essentially acting as a folate antagonist. LEEVARIN 15 TABLET 10'S, on the other hand, is a folate derivative, meaning it's a form of folate that doesn't need to be processed by dihydrofolate reductase before the body can use it for DNA synthesis. This is a key difference in their mechanisms.
• Interestingly, leucovorin can have a dual role when it comes to chemotherapy. While it protects healthy cells from the harmful effects of drugs like methotrexate, it can also boost the effectiveness (and toxicity) of other chemotherapy drugs like 5-fluorouracil. It does this by enhancing the binding of 5-fluorouracil within cancer cells, making the treatment more potent.
• Therefore, LEEVARIN 15 TABLET 10'S is primarily used to rescue or protect normal cells from the adverse effects of methotrexate, particularly in high-dose regimens. By providing a readily usable form of folate, it allows these cells to continue vital processes like DNA synthesis even when methotrexate is present. This helps to reduce side effects such as bone marrow suppression and mucositis.
• In essence, LEEVARIN 15 TABLET 10'S acts as a countermeasure to methotrexate's effects on healthy cells, ensuring that patients can tolerate the chemotherapy regimen better. This allows for potentially more aggressive and effective cancer treatment strategies.

• Your doctor will determine the appropriate dosage and treatment duration of LEEVARIN 15 TABLET 10'S based on your specific medical condition, its severity, and other relevant factors. It's crucial to adhere to your doctor's instructions regarding the medication's usage. This ensures that you receive the maximum benefit from the treatment.
• Administer LEEVARIN 15 TABLET 10'S exactly as directed by your healthcare provider. Avoid altering the dosage or frequency of administration without consulting your doctor. Doing so can impact the medicine's effectiveness and may potentially lead to adverse effects.
• To take LEEVARIN 15 TABLET 10'S, swallow the tablet whole with a full glass of water. Do not break, crush, or chew the tablet, as this can affect how the medication is absorbed into your system. Taking the tablet whole ensures that the medication is released gradually and consistently.
• For optimal results, it's important to take LEEVARIN 15 TABLET 10'S at the same time every day. This helps maintain a consistent level of the medication in your body, which is essential for managing your condition effectively. Setting a daily reminder can help you adhere to your prescribed schedule.