LETHYROX 100MCG TABLET 100'S
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LETHYROX 100MCG TABLET 100'SLETHYROX 100MCG TABLET 100'SLETHYROX 100MCG TABLET 100'S
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LETHYROX 100MCG TABLET 100'S

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LETHYROX 100MCG TABLET 100'S

By INTAS PHARMACEUTICALS LIMITED

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147.84

₹125.66

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About LETHYROX 100MCG TABLET 100'S

  • LETHYROX 100MCG TABLET is a synthetic thyroid hormone (Levothyroxine Sodium) used to treat hypothyroidism, a condition where the thyroid gland doesn't produce enough thyroid hormone. This medication is essential for maintaining normal metabolism, energy levels, and overall well-being. Each tablet contains 100 micrograms of levothyroxine sodium, a precise dosage designed to replace or supplement the body's natural thyroid hormone.
  • Hypothyroidism can manifest in various symptoms such as fatigue, weight gain, constipation, dry skin, and sensitivity to cold. LETHYROX 100MCG TABLET works by providing the body with the necessary thyroid hormone to alleviate these symptoms and restore normal bodily functions. Regular use of this medication, as prescribed by a healthcare professional, helps in regulating metabolism, promoting energy production, and supporting healthy growth and development, especially in children.
  • The active ingredient, Levothyroxine Sodium, is a synthetic form of thyroxine (T4), which is converted into triiodothyronine (T3), the active form of thyroid hormone, in the body. This conversion ensures that the body receives the necessary hormonal support to function optimally. LETHYROX 100MCG TABLET is carefully formulated to provide a consistent and reliable dosage, ensuring effective treatment of hypothyroidism.
  • LETHYROX is typically taken once daily, preferably on an empty stomach, to enhance absorption. It's crucial to follow your doctor's instructions regarding dosage and timing. Regular monitoring of thyroid hormone levels is essential to ensure that the dosage is appropriately adjusted to meet individual needs. Consistent use of LETHYROX 100MCG TABLET helps manage hypothyroidism effectively, improving the quality of life for those affected by thyroid hormone deficiency. This pack contains 100 tablets.

Uses of LETHYROX 100MCG TABLET 100'S

  • Treatment of Hypothyroidism
  • Lowering Thyroid Stimulating Hormone (TSH) levels
  • Management of Thyroid Cancer
  • Treatment of Goiter
  • Hormone replacement therapy after thyroid removal
  • Treatment of Cretinism

How LETHYROX 100MCG TABLET 100'S Works

  • LETHYROX 100MCG TABLET 100'S contains levothyroxine sodium, a synthetic form of thyroxine (T4), which is a naturally occurring thyroid hormone. The thyroid gland normally produces T4 and triiodothyronine (T3), which regulate the body's metabolism. LETHYROX is prescribed when the thyroid gland doesn't produce enough thyroid hormone, a condition known as hypothyroidism. This medication effectively replaces or supplements the missing thyroid hormone, restoring normal hormone levels and alleviating the symptoms of hypothyroidism.
  • Once ingested, levothyroxine is absorbed into the bloodstream. A significant portion of T4 is then converted into T3, the more active form of the hormone, in various tissues and organs throughout the body, including the liver and kidneys. T3 binds to thyroid hormone receptors within cells, initiating a cascade of events that affect gene expression and protein synthesis. This, in turn, influences a wide range of physiological processes.
  • The primary action of thyroid hormones is to stimulate metabolism. They increase the basal metabolic rate, which is the rate at which the body burns calories at rest. This leads to increased oxygen consumption and heat production. Thyroid hormones also play a crucial role in growth and development, particularly in the brain and nervous system. They are essential for normal brain development in infants and children and contribute to cognitive function and mood in adults.
  • Furthermore, LETHYROX influences the metabolism of carbohydrates, fats, and proteins. It promotes the breakdown of carbohydrates, increases the mobilization of fats, and stimulates protein synthesis. Thyroid hormones also affect cardiovascular function by increasing heart rate and contractility. They regulate cholesterol levels and play a role in maintaining healthy bone density. By restoring adequate thyroid hormone levels, LETHYROX effectively reverses the symptoms of hypothyroidism, such as fatigue, weight gain, constipation, dry skin, and slowed heart rate. Regular monitoring of thyroid hormone levels is important to ensure that the dosage is appropriate and to avoid over- or under-replacement.

Side Effects of LETHYROX 100MCG TABLET 100'SArrow

LETHYROX 100MCG TABLET 100'S may cause several side effects, although not everyone experiences them. Common side effects include: weight changes, headache, tremors, sweating, palpitations (fast or irregular heartbeat), nervousness, irritability, insomnia (difficulty sleeping), diarrhea, muscle weakness, and menstrual irregularities. Less common side effects can include: chest pain, heat intolerance, hair loss (usually temporary), vomiting, appetite changes, and leg cramps. Rare but serious side effects include: allergic reactions (rash, itching, swelling), seizures, and heart problems. If you experience any of these side effects, especially severe or persistent ones, consult your doctor immediately.

Safety Advice for LETHYROX 100MCG TABLET 100'SArrow

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Allergies

Allergies

Do not consume LETHYROX 100MCG TABLET 100'S if you are allergic to it.

Dosage of LETHYROX 100MCG TABLET 100'SArrow

  • The dosage of 'LETHYROX 100MCG TABLET 100'S' is highly individualized and depends on several factors, including the severity of hypothyroidism, the patient's age, weight, cardiovascular status, concomitant medical conditions (including pregnancy), co-administered medications, and the TSH (thyroid-stimulating hormone) level. It is crucial to work closely with your physician to determine the appropriate starting dose and to monitor your response to the medication through regular blood tests. Initial dosages typically range from 1.6 to 1.7 mcg per kg of body weight per day. However, this may be adjusted based on individual needs and laboratory results.
  • For adults with overt hypothyroidism, a common starting dose is 50 mcg daily, with adjustments made in 25 mcg increments every 2 to 4 weeks until TSH levels are within the target range. In patients with cardiovascular disease, a lower starting dose of 12.5 to 25 mcg daily is recommended to avoid stressing the heart. Gradual dose increases are then implemented, with close monitoring of cardiac function.
  • Elderly patients may also require lower starting doses and slower titration schedules due to age-related physiological changes and potential co-morbidities. Similarly, individuals with underlying cardiac conditions should be started on a reduced dosage to minimize the risk of adverse cardiovascular events. Monitoring TSH levels approximately 6 to 8 weeks after each dosage adjustment is essential to ensure optimal thyroid hormone replacement.
  • Maintenance dosage varies from person to person. The average full replacement dose of levothyroxine is approximately 125 mcg per day (range 100 to 200 mcg per day). Failing to take the medicine on time can cause the TSH levels to fluctuate and may lead to other symptoms.
  • Take 'LETHYROX 100MCG TABLET 100'S' only as per the prescription by your physician only

What if I miss my dose of LETHYROX 100MCG TABLET 100'S?Arrow

  • If you miss a dose of LETHYROX 100MCG TABLET 100'S, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How to store LETHYROX 100MCG TABLET 100'S?Arrow

  • Keep LETHYROX 100MCG TAB 1X100 away from the reach of children and pets.
  • Store LETHYROX 100MCG TAB 1X100 at room temperature.

Benefits of LETHYROX 100MCG TABLET 100'SArrow

  • LETHYROX 100MCG TABLET 100'S is a synthetic form of thyroxine (T4), a crucial hormone produced by the thyroid gland. Its primary benefit lies in effectively treating hypothyroidism, a condition where the thyroid gland doesn't produce enough thyroid hormone. This medication restores the body's thyroid hormone levels to normal, alleviating a wide range of symptoms associated with hypothyroidism.
  • One of the key benefits of LETHYROX is its ability to improve energy levels and reduce fatigue. Hypothyroidism often leads to persistent tiredness and a lack of energy. By supplementing with thyroxine, LETHYROX helps restore metabolic function, leading to increased energy and vitality.
  • LETHYROX plays a vital role in managing weight. Hypothyroidism can cause weight gain due to a slowed metabolism. By normalizing thyroid hormone levels, LETHYROX aids in regulating metabolism, which can assist in weight management and prevent further weight gain. Note that LETHYROX is not a weight-loss drug and should only be used when thyroid hormone deficiency is confirmed by a doctor.
  • Cognitive function is often impaired in individuals with hypothyroidism. LETHYROX can improve mental clarity, concentration, and memory. By restoring thyroid hormone balance, it helps optimize brain function, leading to improved cognitive performance and overall mental well-being.
  • Hypothyroidism can negatively impact mood, leading to depression and anxiety. LETHYROX helps stabilize mood by ensuring adequate thyroid hormone levels, which are essential for the proper functioning of neurotransmitters in the brain. This can lead to a reduction in symptoms of depression and anxiety, promoting a more positive emotional state.
  • LETHYROX also benefits individuals experiencing symptoms like dry skin, hair loss, and brittle nails, which are common manifestations of hypothyroidism. By addressing the underlying thyroid hormone deficiency, LETHYROX can improve the health and appearance of skin, hair, and nails.
  • The medication aids in regulating body temperature. Hypothyroidism often causes sensitivity to cold. By supplementing with LETHYROX, individuals can experience a more normal body temperature and reduced sensitivity to cold environments.
  • LETHYROX is also crucial for maintaining regular bowel movements. Constipation is a common symptom of hypothyroidism. By restoring normal thyroid function, LETHYROX helps regulate bowel movements and alleviate constipation.
  • Furthermore, LETHYROX helps in regulating menstrual cycles in women. Hypothyroidism can cause irregular periods or heavy bleeding. By ensuring adequate thyroid hormone levels, LETHYROX can help restore regular menstrual cycles.
  • LETHYROX is essential for overall health and well-being when the thyroid gland is underactive. It improves multiple facets of life and physical health.

How to use LETHYROX 100MCG TABLET 100'SArrow

  • LETHYROX 100MCG TABLET is primarily used to treat hypothyroidism, a condition where the thyroid gland doesn't produce enough thyroid hormone. It is crucial to take LETHYROX exactly as prescribed by your doctor. The dosage is individualized and depends on factors such as your age, weight, medical condition, and the severity of your hypothyroidism. Typically, it is taken once daily on an empty stomach, preferably 30-60 minutes before breakfast.
  • Consistency is key when taking LETHYROX. Choose a time that is easy to remember and stick to it. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless specifically instructed by your doctor. Certain medications and supplements can interfere with the absorption of levothyroxine. These include calcium supplements, iron supplements, antacids containing aluminum or magnesium, and some cholesterol-lowering drugs. If you are taking any of these, take them several hours before or after taking LETHYROX.
  • It's essential to have your thyroid hormone levels checked regularly by your doctor, especially when you first start taking LETHYROX or if your dosage is adjusted. This will help ensure that you are receiving the correct amount of medication. Symptoms of hypothyroidism, such as fatigue, weight gain, constipation, and dry skin, should gradually improve as your body's thyroid hormone levels normalize. It may take several weeks to feel the full effects of the medication. Do not stop taking LETHYROX without consulting your doctor, even if you feel better. Discontinuing the medication abruptly can lead to a return of hypothyroid symptoms. If you experience symptoms of hyperthyroidism (overactive thyroid), such as rapid heartbeat, anxiety, weight loss, or tremors, contact your doctor immediately.

Quick Tips for LETHYROX 100MCG TABLET 100'SArrow

  • **Take LETHYROX 100MCG TABLET on an Empty Stomach:** For optimal absorption, administer LETHYROX 100MCG TABLET first thing in the morning, at least 30-60 minutes before your first meal. This consistent routine ensures the medication is properly absorbed into your bloodstream, maximizing its effectiveness in regulating your thyroid hormone levels. Food, especially certain items like fiber-rich foods, calcium, and iron supplements, can interfere with the absorption of levothyroxine.
  • **Maintain Consistent Timing:** Establish a daily schedule for taking LETHYROX 100MCG TABLET and stick to it as closely as possible. This consistency helps maintain stable thyroid hormone levels in your body, leading to more predictable and effective symptom management. Set a reminder on your phone or incorporate it into your morning routine to avoid missing doses.
  • **Avoid Certain Medications and Supplements Simultaneously:** Be mindful of other medications and supplements you're taking, as some can interfere with levothyroxine absorption. Calcium carbonate, iron supplements, antacids containing aluminum or magnesium, and certain cholesterol-lowering drugs (like cholestyramine) can reduce the effectiveness of LETHYROX 100MCG TABLET. If you need to take any of these, do so several hours before or after taking your levothyroxine dose. Always consult your doctor or pharmacist for guidance on potential interactions.
  • **Regular Monitoring of Thyroid Hormone Levels:** Schedule regular blood tests with your healthcare provider to monitor your thyroid hormone levels (TSH, T4, and T3). These tests are crucial for ensuring that your LETHYROX 100MCG TABLET dosage is correctly calibrated to meet your individual needs. Dosage adjustments may be necessary based on these test results, especially during pregnancy, with changes in weight, or if you start or stop other medications.
  • **Be Aware of Symptoms and Report Changes:** Pay close attention to any changes in your symptoms, whether they indicate hypothyroidism (fatigue, weight gain, constipation, dry skin, sensitivity to cold) or hyperthyroidism (anxiety, weight loss, rapid heartbeat, sweating, insomnia). Report any new or worsening symptoms to your doctor promptly, as they may indicate a need for dosage adjustment. Never adjust your dosage on your own without consulting your healthcare provider.
  • **Store Properly:** Store LETHYROX 100MCG TABLET at room temperature, away from direct sunlight and moisture. Keep the medication in its original packaging to protect it from light exposure. Proper storage helps maintain the drug's stability and effectiveness. Avoid storing in the bathroom due to humidity.
  • **Inform Healthcare Providers:** Always inform all your healthcare providers, including your doctor, pharmacist, and dentist, that you are taking LETHYROX 100MCG TABLET. This information is crucial for preventing potential drug interactions and ensuring that you receive appropriate medical care. Carry a list of all your medications with you.
  • **What to do if you Miss a Dose:** If you miss a dose of LETHYROX 100MCG TABLET, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one, as this can lead to an overdose and adverse effects.

Food Interactions with LETHYROX 100MCG TABLET 100'SArrow

  • To ensure optimal absorption of LETHYROX, it is crucial to take it on an empty stomach, ideally 30-60 minutes before your first meal of the day. Certain substances can interfere with the absorption of levothyroxine, the active ingredient in LETHYROX.
  • Avoid taking LETHYROX simultaneously with foods or supplements containing calcium, iron, or soy products, as these can significantly reduce the amount of levothyroxine your body absorbs. If you take these substances, separate their intake from LETHYROX by at least 4 hours.
  • Dietary fiber can also affect levothyroxine absorption. Maintain a consistent fiber intake to avoid fluctuations in your thyroid hormone levels. Consult your doctor if you make significant changes to your fiber consumption.
  • Grapefruit juice and coffee might also affect the absorption of LETHYROX. While more research is needed, it's best to consume them separately from your medication.
  • Always follow your doctor's instructions regarding food and medication interactions to maintain stable thyroid hormone levels and optimal health.

FAQs

What is LETHYROX 100MCG TABLET and what is it used for?Arrow

LETHYROX 100MCG TABLET contains levothyroxine, which is a synthetic thyroid hormone. It is used to treat hypothyroidism (underactive thyroid), a condition where the thyroid gland doesn't produce enough thyroid hormone.

How should I take LETHYROX 100MCG TABLET?Arrow

LETHYROX 100MCG TABLET is usually taken on an empty stomach in the morning, at least 30 minutes before food. Follow your doctor's instructions and do not change the dosage.

What are the common side effects of LETHYROX 100MCG TABLET?Arrow

Common side effects of LETHYROX 100MCG TABLET include nervousness, anxiety, difficulty sleeping, weight loss, increased appetite, heat sensitivity, excessive sweating, headache, tremors, irregular menstrual periods, and rapid heartbeat.

How should I store LETHYROX 100MCG TABLET?Arrow

Store LETHYROX 100MCG TABLET at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can I take other medications while taking LETHYROX 100MCG TABLET?Arrow

LETHYROX 100MCG TABLET can interact with other medications. Inform your doctor about all the medicines, vitamins, and herbal supplements you are taking.

What are the symptoms of an overdose of LETHYROX 100MCG TABLET?Arrow

Symptoms of an overdose of LETHYROX 100MCG TABLET include rapid heartbeat, nervousness, tremors, anxiety, diarrhea, excessive sweating, chest pain, and irregular heartbeat.

What foods and drinks should I avoid while taking LETHYROX 100MCG TABLET?Arrow

Some foods and drinks should be avoided while taking LETHYROX 100MCG TABLET as they may interfere with the absorption of the medicine, such as soy products, walnuts, high-fiber foods, and caffeinated beverages.

Is LETHYROX 100MCG TABLET safe during pregnancy?Arrow

LETHYROX 100MCG TABLET is generally safe during pregnancy, but the dosage may need to be adjusted. Talk to your doctor if you are pregnant or planning to become pregnant.

Is LETHYROX 100MCG TABLET safe during breastfeeding?Arrow

LETHYROX 100MCG TABLET is generally safe during breastfeeding. The medicine passes into breast milk in small amounts, but it is not considered harmful to the infant.

What happens if I miss a dose of LETHYROX 100MCG TABLET?Arrow

If you miss a dose of LETHYROX 100MCG TABLET, take it as soon as you remember, unless it is close to your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

How long does it take for LETHYROX 100MCG TABLET to start working?Arrow

It may take several weeks for LETHYROX 100MCG TABLET to start working. It may take some time before you see an improvement in your symptoms, and it may take several months for your thyroid hormone levels to normalize.

Are there any alternatives to LETHYROX 100MCG TABLET?Arrow

The main alternatives to LETHYROX 100MCG TABLET are other brand name levothyroxine medications. Natural thyroid hormones are also available, but they are not as standardized as levothyroxine.

Are LETHYROX and Thyronorm the same?Arrow

Both LETHYROX and Thyronorm contain levothyroxine, which is a synthetic thyroid hormone. Both are used to treat hypothyroidism. However, they are made by different manufacturers and may have some differences in inactive ingredients.

Can LETHYROX 100MCG TABLET cause weight gain?Arrow

LETHYROX 100MCG TABLET does not typically cause weight gain. In fact, it can help to reverse weight gain caused by hypothyroidism by restoring normal thyroid hormone levels. However, some individuals may experience an increase in appetite after starting the medication, which could lead to weight gain.

Can LETHYROX 100MCG TABLET cause hair loss?Arrow

In some cases, LETHYROX 100MCG TABLET can cause hair loss, especially in the first few months of starting the medication or when the dosage is changed. This side effect is usually temporary and resolves once thyroid hormone levels stabilize.

References

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LEVOXYL (levothyroxine sodium) tablets, for oral use. US FDA Label. Contains information on composition, clinical studies, and usage.

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Levothyroxine. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.

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Braverman LE, Utiger RD, editors. Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 1991.

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UpToDate drug information on Levothyroxine. Wolters Kluwer.

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Levothyroxine. DrugBank Online.

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Virili, C., & Centanni, M. (2019). TSH Target, Levothyroxine Dosage, and Hashimoto's Thyroiditis. International Journal of Endocrinology, 2019, 7241346.

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THYROCS. European Medicines Agency. Public assessment report

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