LINANEXT DM 500MG TABLET 10'S
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LINANEXT DM 500MG TABLET 10'S
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LINANEXT DM 500MG TABLET 10'S

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LINANEXT DM 500MG TABLET 10'S

By MSN LABORATORIES PRIVATE LIMITED

MRP

210

₹178.5

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About LINANEXT DM 500MG TABLET 10'S

  • LINANEXT DM 500MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It combines two powerful medications, Linagliptin and Metformin, to effectively control blood sugar levels.
  • Linagliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the release of insulin from the pancreas and decreasing the secretion of glucagon, a hormone that raises blood sugar levels. By enhancing insulin and suppressing glucagon, Linagliptin helps lower blood glucose levels, especially after meals.
  • Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. This allows your body to use insulin more effectively, further reducing blood sugar levels. Metformin also helps to reduce the amount of glucose absorbed from your intestines.
  • Together, Linagliptin and Metformin offer a dual-pronged approach to managing type 2 diabetes. By addressing multiple pathways involved in blood sugar control, LINANEXT DM 500MG TABLET 10'S helps patients achieve and maintain healthier glucose levels. This can lead to improved overall health and a reduced risk of diabetes-related complications.
  • It is crucial to use LINANEXT DM 500MG TABLET 10'S as prescribed by your doctor. They will determine the appropriate dosage and frequency based on your individual needs and medical history. Regular monitoring of blood sugar levels is also essential while taking this medication. Always consult your healthcare provider for any concerns or questions regarding your diabetes management plan.

Uses of LINANEXT DM 500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Used in combination with diet and exercise
  • Management of insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)

How LINANEXT DM 500MG TABLET 10'S Works

  • LINANEXT DM 500MG TABLET 10'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Linagliptin and Metformin. Each component works through different mechanisms to achieve better glycemic control.
  • Linagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 inhibitors work by increasing the amount of incretin hormones in the body. Incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released by the intestine in response to food intake. These hormones stimulate the release of insulin from the pancreas and decrease the secretion of glucagon from the liver. Insulin helps move glucose from the blood into cells, where it can be used for energy. Glucagon, on the other hand, raises blood sugar levels by stimulating the liver to produce glucose. By inhibiting DPP-4, Linagliptin prolongs the action of incretin hormones, leading to increased insulin secretion and decreased glucagon secretion in a glucose-dependent manner. This means that the effect is more pronounced when blood sugar levels are high, and less so when blood sugar levels are normal, reducing the risk of hypoglycemia.
  • Metformin, the second active ingredient, is a biguanide. It primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Metformin reduces hepatic glucose production by inhibiting gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). It also increases insulin sensitivity in peripheral tissues, such as muscle and fat, allowing cells to absorb and utilize glucose more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines into the bloodstream.
  • The combination of Linagliptin and Metformin provides a dual approach to managing blood sugar levels. Linagliptin enhances insulin secretion and reduces glucagon secretion in a glucose-dependent manner, while Metformin decreases glucose production in the liver, improves insulin sensitivity, and reduces glucose absorption. This synergistic effect results in better blood sugar control compared to using either medication alone. LINANEXT DM 500MG TABLET 10'S is typically taken with meals to further help control blood sugar spikes after eating. It's crucial to use this medication in conjunction with a healthy diet and regular exercise for optimal results.

Side Effects of LINANEXT DM 500MG TABLET 10'SArrow

Possible side effects of LINANEXT DM 500MG TABLET 10'S may include: * **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste in the mouth. * **Uncommon:** Hypoglycemia (low blood sugar), skin rash, itching, headache, dizziness. * **Rare:** Lactic acidosis (build-up of lactic acid in the blood), vitamin B12 deficiency, liver problems, allergic reactions. **It is important to note:** This is not an exhaustive list, and other side effects may occur. If you experience any unusual symptoms while taking LINANEXT DM 500MG TABLET 10'S, consult your doctor immediately.

Safety Advice for LINANEXT DM 500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use if you are allergic to linagliptin, metformin or any of the ingredients of LINANEXT DM 500MG TABLET.

Dosage of LINANEXT DM 500MG TABLET 10'SArrow

  • The recommended dosage of LINANEXT DM 500MG TABLET 10'S' varies depending on individual patient factors, including the severity of the diabetes, kidney function, and other medications being taken. It is crucial to adhere strictly to your physician's instructions regarding dosage and timing. Typically, the starting dose for adults is 500 mg once or twice daily, taken with meals to reduce gastrointestinal side effects. The dosage may be gradually increased by your doctor based on your blood glucose levels, usually in increments of 500 mg per week, up to a maximum of 2000 mg per day.
  • For individuals with impaired kidney function, the dosage of LINANEXT DM 500MG TABLET 10'S' needs to be adjusted carefully. Your doctor will assess your kidney function through blood tests and prescribe a lower dose if necessary. It is important to inform your doctor about any kidney problems before starting this medication.
  • The tablets should be swallowed whole with a glass of water and not crushed or chewed. Consistent daily timing is also essential for optimal blood sugar control. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Regular monitoring of blood glucose levels is vital while taking LINANEXT DM 500MG TABLET 10'S'. This helps your doctor assess the effectiveness of the medication and make any necessary dosage adjustments. Attend all scheduled follow-up appointments with your physician and report any unusual symptoms or side effects promptly.
  • Take 'LINANEXT DM 500MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of LINANEXT DM 500MG TABLET 10'S?Arrow

  • If you miss a dose of LINANEXT DM 500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose to catch up.

How to store LINANEXT DM 500MG TABLET 10'S?Arrow

  • Keep LINANEXT DM 500MG TAB 1X10 away from the reach of children and pets.
  • Store LINANEXT DM 500MG TAB 1X10 at room temperature.

Benefits of LINANEXT DM 500MG TABLET 10'SArrow

  • LINANEXT DM 500MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It effectively controls high blood sugar levels in adults when diet and exercise alone are not sufficient. This medication combines two active ingredients, linagliptin and metformin, each working through different mechanisms to provide comprehensive glycemic control.
  • Linagliptin belongs to a class of drugs known as DPP-4 inhibitors. It works by increasing the levels of incretin hormones, which stimulate the release of insulin from the pancreas and decrease the secretion of glucagon from the liver. Insulin helps to move sugar from the blood into other body tissues where it can be used for energy. By increasing insulin secretion in a glucose-dependent manner (meaning it only increases insulin when blood sugar is high), linagliptin helps lower blood sugar levels without the risk of hypoglycemia (low blood sugar) when used alone.
  • Metformin, on the other hand, is a biguanide that primarily works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. It reduces the amount of sugar the liver releases into the bloodstream and helps muscle cells use insulin more effectively. Metformin also has a modest effect on reducing intestinal glucose absorption. Unlike some other diabetes medications, metformin does not typically cause weight gain and may even promote modest weight loss in some individuals.
  • The combination of linagliptin and metformin in LINANEXT DM 500MG TABLET 10'S offers several advantages for managing type 2 diabetes. Firstly, it provides dual action by addressing multiple pathways involved in blood sugar regulation. This can lead to more effective glycemic control compared to using either medication alone. Secondly, the risk of hypoglycemia is relatively low, especially when compared to medications like sulfonylureas. Thirdly, it's convenient, as it reduces the pill burden by combining two medications into a single tablet, improving adherence to treatment.
  • LINANEXT DM 500MG TABLET 10'S helps in delaying or preventing the long-term complications of diabetes, such as kidney damage, nerve problems, vision loss, heart disease, and stroke. By keeping blood sugar levels within the target range, this medication plays a crucial role in preserving overall health and well-being. Regular monitoring of blood sugar levels, adherence to a healthy diet, and regular physical activity are essential components of diabetes management when taking LINANEXT DM 500MG TABLET 10'S.
  • This medicine is typically taken orally, once or twice daily with meals, to minimize gastrointestinal side effects associated with metformin. Dosage is individualized based on the patient's response and tolerance, as determined by the healthcare provider. Common side effects may include nausea, diarrhea, stomach upset, and, rarely, lactic acidosis (a serious metabolic condition with metformin).
  • In summary, LINANEXT DM 500MG TABLET 10'S is a valuable tool in the management of type 2 diabetes, offering a dual-action approach to lower blood sugar levels, reduce the risk of complications, and improve overall health outcomes for individuals with diabetes. Always use under medical supervision.

How to use LINANEXT DM 500MG TABLET 10'SArrow

  • LINANEXT DM 500MG TABLET 10'S should be taken orally, as directed by your physician. Typically, it is prescribed to be taken once or twice daily, preferably with meals, to minimize potential gastrointestinal discomfort. Always adhere to the dosage and frequency prescribed by your doctor. Do not exceed the recommended dose without consulting your healthcare provider.
  • Swallow the tablet whole with a full glass of water. Avoid crushing, chewing, or breaking the tablet, as this could affect the way the medication is released into your system. Taking it at the same time(s) each day will help you remember to take it consistently, maximizing its effectiveness. Consistency is key for maintaining stable blood sugar levels.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. This medication works best when taken regularly and consistently.
  • While taking LINANEXT DM 500MG TABLET 10'S, it is crucial to maintain a healthy lifestyle, including a balanced diet and regular exercise. This medication is intended to be used in conjunction with lifestyle modifications and is not a substitute for them. Monitor your blood sugar levels regularly, as directed by your doctor, to assess how well the medication is working and to make any necessary adjustments to your treatment plan. Report any unusual side effects or concerns to your doctor immediately.
  • Store LINANEXT DM 500MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Before using this medication, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as well as any pre-existing medical conditions you may have. Regular check-ups with your doctor are essential to monitor your overall health and the effectiveness of your diabetes management plan.

Quick Tips for LINANEXT DM 500MG TABLET 10'SArrow

  • Take LINANEXT DM 500MG TABLET 10'S as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting them, even if you feel better. Consistency is key to managing your blood sugar effectively.
  • LINANEXT DM 500MG TABLET 10'S is most effective when taken with meals. This helps to slow down the absorption of sugar into your bloodstream, preventing sudden spikes in blood glucose levels. Follow your doctor's instructions regarding timing with meals.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider while taking LINANEXT DM 500MG TABLET 10'S. Keeping a log of your readings can help you and your doctor assess how well the medication is working and make necessary adjustments to your treatment plan. Note any patterns or unusual fluctuations.
  • Maintain a healthy lifestyle in conjunction with taking LINANEXT DM 500MG TABLET 10'S. This includes following a balanced diet, engaging in regular physical activity, and managing stress levels. These lifestyle modifications can significantly improve your blood sugar control and overall health. Discuss specific dietary and exercise recommendations with your doctor or a registered dietitian.
  • Be aware of the potential side effects of LINANEXT DM 500MG TABLET 10'S, such as nausea, diarrhea, or stomach upset. If you experience any persistent or bothersome side effects, inform your doctor promptly. They can provide guidance on managing these effects or adjust your medication if necessary. Also, stay hydrated and avoid excessive alcohol consumption, as these can exacerbate certain side effects and impact blood sugar control. Remember to discuss all other medications and supplements you are taking with your doctor, as they may interact with LINANEXT DM 500MG TABLET 10'S.

Food Interactions with LINANEXT DM 500MG TABLET 10'SArrow

  • LINANEXT DM 500MG TABLET 10'S should be taken orally as directed by your doctor.
  • Generally, it is recommended to take this medication with food to minimize the risk of stomach upset or gastrointestinal side effects.
  • Following a consistent pattern of taking it before, during, or after meals can help maintain stable blood sugar levels.
  • Specific dietary recommendations or restrictions may be provided by your doctor based on your overall health condition and response to the medication.

FAQs

What is the use of LINANEXT DM 500MG TABLET 10'S?Arrow

LINANEXT DM 500MG TABLET 10'S is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

How does LINANEXT DM 500MG TABLET 10'S work?Arrow

Linagliptin works by inhibiting the DPP-4 enzyme, increasing the amount of insulin released after meals and decreasing the amount of sugar made by the liver. Metformin works by decreasing the amount of sugar made by the liver, decreasing the absorption of sugar from the intestines, and increasing the body's sensitivity to insulin.

What are the common side effects of LINANEXT DM 500MG TABLET 10'S?Arrow

Common side effects of LINANEXT DM 500MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is LINANEXT DM 500MG TABLET 10'S safe for patients with kidney problems?Arrow

LINANEXT DM 500MG TABLET 10'S should be used with caution in patients with kidney problems. Dosage may need to be adjusted based on kidney function. Consult your doctor.

Is LINANEXT DM 500MG TABLET 10'S safe during pregnancy?Arrow

The safety of LINANEXT DM 500MG TABLET 10'S during pregnancy is not established. It should only be used if the potential benefit outweighs the risk to the fetus. Consult your doctor.

Is LINANEXT DM 500MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether LINANEXT DM 500MG TABLET 10'S is excreted in human breast milk. Consult your doctor before using it during breastfeeding.

What is the recommended dosage of LINANEXT DM 500MG TABLET 10'S?Arrow

The dosage of LINANEXT DM 500MG TABLET 10'S will be determined by your doctor based on your medical condition and response to treatment.

Can LINANEXT DM 500MG TABLET 10'S be taken with or without food?Arrow

It is recommended to take LINANEXT DM 500MG TABLET 10'S with food to reduce the chance of stomach upset.

What happens if I miss a dose of LINANEXT DM 500MG TABLET 10'S?Arrow

If you miss a dose of LINANEXT DM 500MG TABLET 10'S, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

How should I store LINANEXT DM 500MG TABLET 10'S?Arrow

Store LINANEXT DM 500MG TABLET 10'S at room temperature, away from heat and moisture. Keep it out of reach of children.

Can LINANEXT DM 500MG TABLET 10'S interact with other medications?Arrow

LINANEXT DM 500MG TABLET 10'S can interact with certain other medications. Tell your doctor about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements.

What precautions should I take while taking LINANEXT DM 500MG TABLET 10'S?Arrow

While taking LINANEXT DM 500MG TABLET 10'S, monitor your blood sugar levels regularly, maintain a healthy diet, and exercise regularly. Limit alcohol consumption.

Does LINANEXT DM 500MG TABLET 10'S cause weight gain?Arrow

LINANEXT DM 500MG TABLET 10'S is not likely to cause weight gain. However, some patients may experience other side effects that could contribute to weight gain.

Can LINANEXT DM 500MG TABLET 10'S be stopped suddenly?Arrow

Do not stop taking LINANEXT DM 500MG TABLET 10'S suddenly. This may cause your blood sugar levels to increase. Consult your doctor before stopping it.

What are the alternatives to LINANEXT DM 500MG TABLET 10'S?Arrow

Alternatives to LINANEXT DM 500MG TABLET 10'S include other antidiabetic medications, such as sulfonylureas, thiazolidinediones, and insulin. Talk to your doctor about the best option for you.

References

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FDA - U.S. Food and Drug Administration: HIGHLIGHTS OF PRESCRIBING INFORMATION - Metformin Hydrochloride Extended-Release Tablets

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DrugBank: Metformin

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PubChem: Metformin

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NCBI: A Review of the Mechanism of Action of Metformin

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European Medicines Agency: Metformin-containing medicinal products Article 31 referral

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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