LINAXA M XR 5MG/500MG TABLET 10'S
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LINAXA M XR 5MG/500MG TABLET 10'SLINAXA M XR 5MG/500MG TABLET 10'SLINAXA M XR 5MG/500MG TABLET 10'S
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LINAXA M XR 5MG/500MG TABLET 10'S

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LINAXA M XR 5MG/500MG TABLET 10'S

By TORRENT PHARMACEUTICALS LIMITED

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141.75

₹120.49

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About LINAXA M XR 5MG/500MG TABLET 10'S

  • LINAXA M XR 5MG/500MG TABLET 10'S is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients: Linagliptin and Metformin Hydrochloride, both of which work through different mechanisms to improve glycemic control.
  • Linagliptin belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the amount of incretin hormones released in the body. These hormones help to increase insulin release from the pancreas and decrease glucagon secretion from the liver, ultimately leading to lower blood sugar levels, especially after meals. Linagliptin offers the advantage of being primarily eliminated through the bile, which means its use is less dependent on kidney function compared to some other similar medications.
  • Metformin Hydrochloride is a biguanide and is considered a first-line treatment for type 2 diabetes. It primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin, allowing cells to use glucose more effectively. Metformin also slows down the absorption of glucose from the intestines. The extended-release (XR) formulation allows for a once-daily dosage, providing a more convenient way to manage blood sugar levels throughout the day.
  • LINAXA M XR is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels. It is important to use this medication as part of a comprehensive diabetes management plan that includes regular monitoring of blood sugar, a healthy diet, and regular physical activity. Potential side effects can include gastrointestinal issues such as nausea, diarrhea, or abdominal discomfort, and it's important to discuss any concerns or existing medical conditions with your healthcare provider before starting this medication.

Uses of LINAXA M XR 5MG/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Managing insulin resistance associated with polycystic ovary syndrome (PCOS)
  • Improve blood sugar control

How LINAXA M XR 5MG/500MG TABLET 10'S Works

  • LINAXA M XR 5MG/500MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It contains two active ingredients: linagliptin and metformin hydrochloride.
  • Linagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 inhibitors work by increasing the amount of incretin hormones in the body. Incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released by the intestine in response to food intake. These hormones stimulate the release of insulin from the pancreas and decrease the secretion of glucagon from the liver. Insulin helps glucose enter cells, thereby lowering blood sugar levels. Glucagon, on the other hand, raises blood sugar levels by prompting the liver to release stored glucose. By inhibiting DPP-4, linagliptin prolongs the action of incretin hormones, resulting in improved blood sugar control, particularly after meals. It works in a glucose-dependent manner, meaning it primarily enhances insulin secretion when blood glucose levels are elevated, reducing the risk of hypoglycemia (low blood sugar).
  • Metformin hydrochloride is a biguanide that works through several mechanisms. Primarily, it reduces glucose production in the liver by suppressing hepatic gluconeogenesis (the process by which the liver creates glucose from non-carbohydrate sources). Metformin also enhances insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. Additionally, metformin slows down the absorption of glucose from the intestines into the bloodstream. Unlike some other diabetes medications, metformin does not directly stimulate insulin secretion, so it carries a lower risk of causing hypoglycemia when used alone. It also has a beneficial effect on lipid profiles and may promote modest weight loss.
  • The extended-release (XR) formulation of LINAXA M XR allows for a once-daily administration. The extended-release mechanism ensures a gradual release of metformin into the body, which helps to minimize gastrointestinal side effects commonly associated with immediate-release metformin. This results in better tolerability and adherence to the medication regimen. Combining linagliptin and metformin in a single tablet offers a convenient way to target multiple pathways involved in blood sugar regulation, leading to more effective glycemic control compared to using either medication alone. It is crucial to take LINAXA M XR as prescribed by your healthcare provider and to follow their recommendations regarding diet and exercise for optimal results.

Side Effects of LINAXA M XR 5MG/500MG TABLET 10'SArrow

The most common side effects of LINAXA M XR 5MG/500MG TABLET may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, and metallic taste. Other possible side effects are hypoglycemia (low blood sugar), headache, dizziness, constipation, upper respiratory tract infection, and weight gain. Less common but potentially serious side effects include lactic acidosis (symptoms include feeling cold, difficulty breathing, dizziness, weakness, fatigue, muscle aches, stomach pain with nausea/vomiting, slow or irregular heartbeat), pancreatitis, and allergic reactions (rash, itching, swelling). In rare cases, it may also cause liver problems and decreased vitamin B12 absorption. Consult your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for LINAXA M XR 5MG/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use LINAXA M XR 5MG/500MG TABLET 10'S if you are allergic to it.

Dosage of LINAXA M XR 5MG/500MG TABLET 10'SArrow

  • The recommended dosage of LINAXA M XR 5MG/500MG TABLET 10'S varies depending on individual patient needs, pre-existing treatments, and kidney function. It is crucial to follow your doctor's instructions precisely. Generally, the starting dose is one tablet taken orally once daily, preferably with the evening meal to minimize gastrointestinal side effects. This helps to coincide the peak metformin levels with food intake, improving tolerability.
  • Your physician may gradually increase the dosage based on your glycemic control and tolerance to the medication. The maximum recommended daily dose is typically two tablets, which provides the maximum daily dose of linagliptin and metformin. The tablets should be swallowed whole and not crushed, split, or chewed, as this can affect the extended-release properties of the medication and lead to altered drug release and potentially increased side effects. It is essential to maintain regular monitoring of your blood glucose levels, as directed by your doctor, to assess the effectiveness of the treatment and make any necessary dosage adjustments.
  • Patients with mild to moderate kidney impairment may require dosage adjustments, and this medication is generally not recommended for individuals with severe kidney disease. Your doctor will assess your kidney function before and during treatment with LINAXA M XR 5MG/500MG TABLET 10'S. Consistency in taking the medication at the same time each day is important for maintaining stable blood glucose levels. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Take 'LINAXA M XR 5MG/500MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

  • If you miss a dose of LINAXA M XR 5MG/500MG TABLET 10'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

  • Keep LINAXA M XR 5/500MG TAB 1X10 away from the reach of children and pets.
  • Store LINAXA M XR 5/500MG TAB 1X10 at room temperature.

Benefits of LINAXA M XR 5MG/500MG TABLET 10'SArrow

  • LINAXA M XR 5MG/500MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It combines two oral antidiabetic medicines: linagliptin and metformin. By effectively managing blood sugar levels, LINAXA M XR offers a multitude of benefits for individuals with type 2 diabetes.
  • One of the primary benefits of LINAXA M XR is its ability to lower blood sugar levels. Linagliptin works by enhancing the levels of incretin hormones, which stimulate the release of insulin after a meal and reduce the secretion of glucagon (a hormone that raises blood sugar). Metformin, on the other hand, reduces glucose production in the liver and improves insulin sensitivity. This dual action helps to keep blood sugar levels within a healthy range.
  • Improved Glycemic Control: Consistent use of LINAXA M XR contributes to better overall glycemic control, reflected in lower HbA1c levels. HbA1c provides an average measure of blood sugar levels over the past 2-3 months, offering a comprehensive view of diabetes management.
  • Reduced Risk of Diabetes Complications: By maintaining stable blood sugar levels, LINAXA M XR helps to reduce the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems.
  • Weight Management: Metformin, one of the components of LINAXA M XR, is often associated with modest weight loss or weight stabilization. This can be particularly beneficial for individuals with type 2 diabetes who are overweight or obese.
  • Cardiovascular Benefits: Some studies suggest that linagliptin may have cardiovascular benefits, potentially reducing the risk of heart-related events in individuals with type 2 diabetes. Metformin has also shown some cardiovascular protective effects in certain populations.
  • Convenient Dosing: LINAXA M XR is typically taken once or twice daily with meals, making it a convenient option for many individuals. The extended-release (XR) formulation allows for once-daily dosing, further enhancing convenience and adherence.
  • Improved Insulin Sensitivity: Metformin helps to improve the body's response to insulin, allowing it to use glucose more effectively. This is particularly important in type 2 diabetes, where insulin resistance is a common problem.
  • Reduced Hepatic Glucose Production: Metformin works by decreasing the amount of glucose produced by the liver. This helps to lower fasting blood sugar levels and prevent excessive glucose release into the bloodstream.
  • Complementary Action: Linagliptin and metformin work through different mechanisms to lower blood sugar levels. Their complementary action provides a more comprehensive approach to diabetes management compared to using either medication alone.
  • Enhanced Quality of Life: By effectively managing blood sugar levels and reducing the risk of complications, LINAXA M XR can contribute to an improved quality of life for individuals with type 2 diabetes. This includes increased energy levels, reduced fatigue, and greater overall well-being.
  • Overall, LINAXA M XR 5MG/500MG TABLET 10'S offers a comprehensive approach to managing type 2 diabetes by effectively lowering blood sugar levels, reducing the risk of complications, and improving overall health. It is important to take this medicine as prescribed by your doctor and to follow a healthy diet and exercise plan to maximize its benefits.

How to use LINAXA M XR 5MG/500MG TABLET 10'SArrow

  • LINAXA M XR 5MG/500MG TABLET 10'S should be taken orally, usually once daily with the evening meal. It is crucial to swallow the tablet whole with a full glass of water and do not crush, chew, or break it, as this can affect how the medication is released in your body, potentially leading to side effects or reduced effectiveness.
  • The dosage of LINAXA M XR is typically determined by your doctor based on your specific condition, blood sugar levels, and response to treatment. Adhere strictly to the prescribed dosage and schedule. Do not alter the dosage without consulting your doctor.
  • Consistency is key. Taking LINAXA M XR at the same time each day helps maintain a steady level of medication in your bloodstream, which is crucial for optimal blood sugar control. Set a reminder if needed to avoid missing doses.
  • Before starting LINAXA M XR, inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medicines, and herbal supplements, to avoid potential drug interactions.
  • Regular monitoring of your blood sugar levels is essential while taking LINAXA M XR. Follow your doctor's instructions for blood glucose monitoring and keep a record of your readings to share with your healthcare provider. This information helps them adjust your treatment plan as needed.
  • LINAXA M XR works best when combined with a healthy diet and regular exercise. Follow your doctor's or dietitian's recommendations for a balanced meal plan and incorporate physical activity into your daily routine to improve blood sugar control and overall health.
  • If you experience any unusual side effects while taking LINAXA M XR, such as persistent nausea, vomiting, abdominal pain, or signs of an allergic reaction (rash, itching, swelling), seek immediate medical attention.
  • Store LINAXA M XR at room temperature, away from moisture and heat. Keep the medication out of reach of children.
  • If you miss a dose of LINAXA M XR, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • It is important to understand that LINAXA M XR is part of a comprehensive treatment plan for diabetes. Continue to follow your doctor's recommendations for diet, exercise, and other medications to effectively manage your condition.

Quick Tips for LINAXA M XR 5MG/500MG TABLET 10'SArrow

  • Take LINAXA M XR as prescribed by your doctor, usually once daily with the evening meal to minimize stomach upset. Swallow the tablet whole; do not crush, chew, or break it to maintain its extended-release properties and ensure consistent medication delivery. Adhering to your doctor's instructions regarding dosage and timing is crucial for effective blood sugar control.
  • LINAXA M XR helps control blood sugar levels but does not cure diabetes. Continue following your diet and exercise plan as recommended by your healthcare provider. Regular physical activity and a balanced diet are essential components of managing diabetes effectively and maximizing the benefits of LINAXA M XR.
  • Monitor your blood sugar levels regularly as advised by your doctor. Keep a record of your readings and share them with your healthcare provider during your check-ups. This helps in assessing the effectiveness of the medication and making necessary adjustments to your treatment plan.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, and confusion. Carry a source of fast-acting sugar, like glucose tablets or juice, with you at all times. If you experience symptoms of hypoglycemia, consume the fast-acting sugar immediately and inform your doctor.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with LINAXA M XR. Certain medications can affect blood sugar levels, so your doctor may need to adjust your dosage accordingly. Always disclose your complete medication list to ensure safe and effective treatment.

Food Interactions with LINAXA M XR 5MG/500MG TABLET 10'SArrow

  • LINAXA M XR 5MG/500MG TABLET 10'S should be taken preferably with food to decrease the possibility of a stomach upset. Avoid excessive alcohol intake while taking this medication, as it can increase the risk of side effects, such as low blood sugar (hypoglycemia). Consult your doctor for specific dietary advice tailored to your condition and other medications.

FAQs

What is LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

LINAXA M XR 5MG/500MG TABLET 10'S is a medication containing a combination of linagliptin and metformin. It is used to treat type 2 diabetes.

What is LINAXA M XR 5MG/500MG TABLET 10'S used for?Arrow

It is used to control blood sugar levels in people with type 2 diabetes along with diet and exercise.

How does LINAXA M XR 5MG/500MG TABLET 10'S work?Arrow

Linagliptin works by inhibiting the DPP-4 enzyme, which increases insulin secretion. Metformin reduces the amount of glucose produced by the liver and improves the body's sensitivity to insulin.

What are the common side effects of LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

Common side effects include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is LINAXA M XR 5MG/500MG TABLET 10'S safe during pregnancy?Arrow

Its safety during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

Is LINAXA M XR 5MG/500MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether this medication is excreted in breast milk. Consult your doctor before breastfeeding.

What is the dosage of LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

The dosage is based on your medical condition and response to treatment. Follow your doctor's instructions.

Can LINAXA M XR 5MG/500MG TABLET 10'S be taken with or without food?Arrow

It is usually recommended to take it with food to avoid stomach upset.

What happens if I miss a dose of LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

How to store LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

Store it at room temperature, away from heat and moisture.

Is it safe to consume alcohol with LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

Avoid consuming alcohol as it can lower blood sugar levels and increase side effects.

Is LINAXA M XR 5MG/500MG TABLET 10'S safe for people with kidney disease?Arrow

People with kidney disease should use it with caution as metformin can worsen kidney problems.

What are the symptoms of an overdose of LINAXA M XR 5MG/500MG TABLET 10'S?Arrow

Symptoms of overdose may include nausea, vomiting, abdominal pain, dizziness, and in severe cases, lactic acidosis.

Can LINAXA M XR 5MG/500MG TABLET 10'S interact with other medications?Arrow

Yes, it can interact with certain other medications. Tell your doctor about all the medications you are taking.

Does LINAXA M XR 5MG/500MG TABLET 10'S cause weight gain?Arrow

It does not typically cause weight gain, but it can happen in some individuals.

References

Book Icon

KOMBIGLYZE XR (saxagliptin and metformin hydrochloride extended-release) tablets, for oral use. Full Prescribing Information. Initial U.S. Approval: 2010. Document includes information on clinical studies, pharmacology, and safety.

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Saxagliptin. DrugBank Online. Comprehensive information including chemical structure, pharmacology, interactions, and metabolism.

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Metformin. DrugBank Online. Comprehensive information including chemical structure, pharmacology, interactions, and metabolism.

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DeFronzo RA, et al. Combination therapy with saxagliptin and metformin improves glycemic control in patients with type 2 diabetes mellitus. Int J Clin Pract. 2014 Jul;68(7):828-38. doi: 10.1111/ijcp.12382. PubMed Central. Research article on the efficacy of the saxagliptin and metformin combination.

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Komboglyze. European Medicines Agency. European public assessment report (EPAR) for Komboglyze, which contains information on the medicine’s approval process, scientific assessment, and patient information.

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McCarthy CG, et al. Efficacy and safety of saxagliptin added to metformin in patients with type 2 diabetes mellitus inadequately controlled with metformin alone: a meta-analysis. Diabetes Metab Syndr Obes. 2018 Oct 17;11:625-634. doi: 10.2147/DMSO.S176333. eCollection 2018. PubMed Central. Meta-analysis of saxagliptin added to metformin.

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LINAXA M XR 5MG/500MG TABLET 10'S

LINAXA M XR 5MG/500MG TABLET 10'S

MRP

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₹120.49

15 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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