LOBG M 0.5/500MG TABLET 15'S
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LOBG M 0.5/500MG TABLET 15'S
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LOBG M 0.5/500MG TABLET 15'S

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LOBG M 0.5/500MG TABLET 15'S

By GLENMARK PHARMACEUTICALS LIMITED

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150.93

₹128.29

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About LOBG M 0.5/500MG TABLET 15'S

  • LOBG M 0.5/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It combines Lobeglitazone and Metformin, working synergistically to control high blood sugar levels. Lobeglitazone is a thiazolidinedione (TZD) which increases insulin sensitivity, allowing the body to use insulin more effectively. Metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity. This dual action helps in maintaining optimal blood sugar levels throughout the day.
  • This medication is typically prescribed when diet and exercise alone are not sufficient to manage blood sugar levels in patients with type 2 diabetes. By improving insulin sensitivity and reducing glucose production, LOBG M 0.5/500MG TABLET helps prevent the long-term complications associated with diabetes, such as kidney damage, nerve problems, vision loss, and heart disease. Regular monitoring of blood sugar levels and adherence to a healthy lifestyle are crucial while taking this medicine.
  • LOBG M 0.5/500MG TABLET should be taken as directed by your doctor, usually once or twice daily with meals to minimize gastrointestinal side effects. Common side effects may include nausea, diarrhea, stomach upset, and headache. It is essential to inform your doctor about any other medications you are taking, as drug interactions can occur. Patients with severe kidney or liver disease should use this medication with caution. Regular check-ups with your healthcare provider are important to monitor kidney function and overall health while on this treatment.
  • Each LOBG M 0.5/500MG tablet contains 0.5mg of Lobeglitazone and 500mg of Metformin hydrochloride. These ingredients work together to improve glycemic control in individuals with type 2 diabetes mellitus. Proper storage is essential to maintain the medication's efficacy; store at room temperature, away from moisture and direct sunlight, and keep out of reach of children.

Uses of LOBG M 0.5/500MG TABLET 15'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin resistance in polycystic ovary syndrome (PCOS)
  • Reducing the risk of heart disease (in some cases)
  • Improve blood sugar control

How LOBG M 0.5/500MG TABLET 15'S Works

  • LOBG M 0.5/500MG TABLET 15'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Lobeglitazone and Metformin. Each component works through different mechanisms to achieve better glycemic control.
  • Lobeglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It primarily functions by improving insulin sensitivity in the body. Insulin is a hormone that helps glucose (sugar) enter cells to be used for energy. In type 2 diabetes, cells become resistant to insulin, leading to elevated blood sugar levels. Lobeglitazone works by activating a receptor called PPARγ (peroxisome proliferator-activated receptor gamma). This activation leads to increased expression of genes involved in glucose and lipid metabolism, ultimately enhancing the body's response to insulin. By making cells more sensitive to insulin, Lobeglitazone helps lower blood sugar levels.
  • Metformin, on the other hand, is a biguanide that works through several mechanisms to lower blood sugar. Firstly, it reduces the production of glucose in the liver. The liver can sometimes produce excessive amounts of glucose, especially in individuals with diabetes. Metformin suppresses this process, leading to a decrease in overall blood sugar levels. Secondly, Metformin increases insulin sensitivity in peripheral tissues (such as muscles). This action complements the effect of Lobeglitazone, further enhancing glucose uptake by cells. Thirdly, Metformin slows down the absorption of glucose from the intestines after a meal. This helps prevent sharp spikes in blood sugar levels following food intake.
  • In summary, LOBG M 0.5/500MG TABLET 15'S works by addressing multiple aspects of type 2 diabetes. Lobeglitazone improves insulin sensitivity, while Metformin reduces glucose production in the liver, enhances insulin sensitivity, and slows down glucose absorption. The combination of these two medications provides a comprehensive approach to managing blood sugar levels effectively. It is important to take this medication as prescribed by your doctor and to follow a healthy diet and exercise plan to optimize its benefits. Regular monitoring of blood sugar levels is also crucial to ensure the medication is working effectively and to adjust the dosage if needed.
  • It is crucial to understand that LOBG M 0.5/500MG TABLET 15'S is intended to be used as part of a comprehensive diabetes management plan, which includes dietary modifications, regular physical activity, and, in some cases, other medications. This multifaceted approach is key to achieving and maintaining optimal blood sugar control and preventing long-term complications associated with diabetes. Always consult with your healthcare provider for personalized advice and to ensure that LOBG M 0.5/500MG TABLET 15'S is the right choice for you.

Side Effects of LOBG M 0.5/500MG TABLET 15'SArrow

Possible side effects of LOBG M 0.5/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, weakness, fatigue, skin rash, itching, and rarely, lactic acidosis. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for LOBG M 0.5/500MG TABLET 15'SArrow

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Allergies

Allergies

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Dosage of LOBG M 0.5/500MG TABLET 15'SArrow

  • The recommended dosage of LOBG M 0.5/500MG TABLET 15'S varies depending on individual patient needs, glucose control, and tolerability. Your doctor will determine the appropriate dose for you. The usual starting dose is one tablet once or twice daily, administered with meals to reduce gastrointestinal discomfort.
  • The maximum daily dose of LOBG M 0.5/500MG TABLET 15'S should not exceed the maximum recommended daily dose of lobeglitazone (0.5 mg) and metformin (2000 mg). Dosage adjustments should be made gradually based on your blood glucose response and as directed by your healthcare provider. It's important to monitor your blood sugar levels regularly while taking this medication to ensure optimal control and to prevent hypoglycemia (low blood sugar).
  • If you miss a dose of LOBG M 0.5/500MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. Always follow your doctor's instructions carefully and do not change your dosage without consulting them first. Take 'LOBG M 0.5/500MG TABLET 15'S' only as per the prescription by your physician only.
  • It is important to note that LOBG M 0.5/500MG TABLET 15'S is intended to be used along with diet and exercise. Following a healthy lifestyle can help you to get the most out of this medicine. Regularly check your blood sugar level as directed by your doctor.
  • Consult your doctor immediately, If you experience any side effects, such as nausea, vomiting, abdominal pain, fatigue or any other unusual symptoms, while on this medication.

What if I miss my dose of LOBG M 0.5/500MG TABLET 15'S?Arrow

  • If you miss a dose of LOBG M 0.5/500MG TABLET 15'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store LOBG M 0.5/500MG TABLET 15'S?Arrow

  • Keep LOBG M 0.5/500MG TAB 1X15 away from the reach of children and pets.
  • Store LOBG M 0.5/500MG TAB 1X15 at room temperature.

Benefits of LOBG M 0.5/500MG TABLET 15'SArrow

  • LOBG M 0.5/500MG TABLET 15'S is a combination medicine used to effectively manage type 2 diabetes mellitus. It combines Lobeglitazone (a thiazolidinedione) and Metformin (a biguanide) to provide comprehensive glycemic control.
  • Lobeglitazone improves insulin sensitivity in peripheral tissues, helping cells utilize glucose more efficiently. This action lowers blood sugar levels, particularly after meals.
  • Metformin reduces glucose production in the liver and enhances insulin sensitivity. It also slows down glucose absorption from the intestines. This dual action helps to lower both fasting and postprandial blood sugar levels.
  • By improving insulin sensitivity and reducing glucose production, LOBG M 0.5/500MG TABLET 15'S helps to lower HbA1c levels, a key indicator of long-term blood sugar control. Consistent use can lead to significant improvements in HbA1c.
  • This medication aids in maintaining stable blood sugar levels throughout the day, reducing the risk of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). This stability is crucial for preventing diabetes-related complications.
  • Effective blood sugar control with LOBG M 0.5/500MG TABLET 15'S can significantly reduce the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems.
  • For individuals with type 2 diabetes who are overweight or obese, LOBG M 0.5/500MG TABLET 15'S can help in modest weight management. Metformin, in particular, has been associated with slight weight loss or weight stabilization in some individuals.
  • LOBG M 0.5/500MG TABLET 15'S offers the convenience of a single tablet containing two different medications, simplifying the treatment regimen and improving adherence. This ease of use can lead to better overall management of diabetes.
  • Regular use of LOBG M 0.5/500MG TABLET 15'S, in conjunction with diet and exercise, can improve overall metabolic health. This includes better cholesterol levels and improved blood pressure, further reducing cardiovascular risk.
  • This medication is often prescribed as part of a comprehensive diabetes management plan. This plan usually includes lifestyle modifications such as diet, exercise, and regular blood sugar monitoring. LOBG M 0.5/500MG TABLET 15'S supports and enhances the effectiveness of these lifestyle changes.
  • LOBG M 0.5/500MG TABLET 15'S helps prevent rapid spikes in blood sugar after meals by improving insulin sensitivity and controlling glucose production. This is particularly beneficial in managing postprandial hyperglycemia.
  • Consistent and effective blood sugar control provided by LOBG M 0.5/500MG TABLET 15'S can lead to increased energy levels and reduced fatigue, common symptoms of poorly managed diabetes. This improvement in energy can enhance overall quality of life.
  • The dual action of Lobeglitazone and Metformin in LOBG M 0.5/500MG TABLET 15'S provides a synergistic effect, meaning that the combination is more effective than either medication used alone. This synergy allows for better blood sugar control with potentially lower doses of each individual medication.
  • LOBG M 0.5/500MG TABLET 15'S is suitable for a wide range of patients with type 2 diabetes, especially those who require more than one medication to achieve their target blood sugar levels. It offers a convenient and effective option for managing this chronic condition.
  • By effectively managing blood sugar levels, LOBG M 0.5/500MG TABLET 15'S contributes to improved cardiovascular health. Stable blood sugar levels reduce the risk of heart disease and stroke, common complications of diabetes.

How to use LOBG M 0.5/500MG TABLET 15'SArrow

  • LOBG M 0.5/500MG TABLET 15'S is an oral medication used to manage type 2 diabetes. It combines Lobeglitazone and Metformin, working through different mechanisms to control blood sugar levels. Always take LOBG M 0.5/500MG TABLET exactly as your doctor prescribes. The usual starting dose is one tablet once or twice daily, taken with meals to reduce the risk of stomach upset. Your doctor may adjust your dosage based on your blood glucose levels and how well you tolerate the medication.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it, as this can affect how the medication is released and absorbed. It is important to take LOBG M 0.5/500MG TABLET at the same time(s) each day to maintain consistent blood sugar control. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • While taking LOBG M 0.5/500MG TABLET, it’s crucial to monitor your blood sugar levels regularly, as directed by your healthcare provider. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. In addition to medication, diet and exercise are essential components of managing type 2 diabetes. Follow the dietary recommendations provided by your doctor or a registered dietitian, and engage in regular physical activity.
  • Be aware of potential side effects, which may include nausea, diarrhea, stomach upset, headache, or muscle pain. If you experience any severe or persistent side effects, contact your doctor immediately. LOBG M 0.5/500MG TABLET can interact with other medications, so it’s important to inform your doctor about all the medicines you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Store LOBG M 0.5/500MG TABLET at room temperature, away from moisture and heat, and keep it out of the reach of children. Regular follow-up appointments with your doctor are necessary to monitor your condition and ensure the safe and effective use of this medication.

Quick Tips for LOBG M 0.5/500MG TABLET 15'SArrow

  • Take LOBG M 0.5/500MG TABLET 15'S as prescribed by your doctor, usually once or twice daily with meals to minimize stomach upset. Consistent timing is key for optimal blood sugar control.
  • Monitor your blood sugar levels regularly while taking LOBG M 0.5/500MG TABLET 15'S. Keep a record and share it with your doctor. This helps to adjust the dosage for best results. A fasting blood sugar test and post-meal test is extremely helpful.
  • Follow a balanced diet and exercise regularly while using LOBG M 0.5/500MG TABLET 15'S. This medication works best when combined with lifestyle changes for effective diabetes management. Consult a dietician for guidance on diet and workout plans.
  • Be aware of the symptoms of low blood sugar (hypoglycemia) such as sweating, shaking, rapid heartbeat, and confusion. Always carry a source of quick sugar like glucose tablets or fruit juice to treat hypoglycemia promptly. Inform your family and friends about how to administer glucagon in case of severe hypoglycemia. Glucagon injection can save lives.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting LOBG M 0.5/500MG TABLET 15'S. Certain medications can interact with this medicine, affecting its efficacy or increasing the risk of side effects. This includes medicines like beta blockers, NSAIDs (like Ibuprofen), and certain antidepressants. Never self-medicate.

Food Interactions with LOBG M 0.5/500MG TABLET 15'SArrow

  • LOBG M 0.5/500MG TABLET 15'S can be taken with or without food. However, it is generally recommended to take it with meals to minimize the risk of gastrointestinal side effects such as nausea or upset stomach. Consistent timing with meals can also help maintain stable blood sugar levels.

FAQs

What is LOBG M 0.5/500MG TABLET 15'S?Arrow

LOBG M 0.5/500MG TABLET 15'S is a medication used to treat type 2 diabetes. It contains two medicines: Lornagliptin and Metformin.

What is LOBG M 0.5/500MG TABLET 15'S used for?Arrow

LOBG M 0.5/500MG TABLET 15'S is used to control blood sugar levels in people with type 2 diabetes.

How does LOBG M 0.5/500MG TABLET 15'S work?Arrow

Lornagliptin works by blocking an enzyme called DPP-4, which inactivates insulin. Metformin works by decreasing the amount of glucose produced by the liver and improving the body's sensitivity to insulin.

What are the common side effects of LOBG M 0.5/500MG TABLET 15'S?Arrow

Common side effects of LOBG M 0.5/500MG TABLET 15'S include nausea, vomiting, diarrhea, and stomach pain.

Is LOBG M 0.5/500MG TABLET 15'S safe?Arrow

LOBG M 0.5/500MG TABLET 15'S is safe for most people when taken as directed by a doctor.

How should I take LOBG M 0.5/500MG TABLET 15'S?Arrow

LOBG M 0.5/500MG TABLET 15'S should be taken exactly as prescribed by your doctor. It is usually taken once or twice a day with meals.

What happens if I miss a dose of LOBG M 0.5/500MG TABLET 15'S?Arrow

If you miss a dose of LOBG M 0.5/500MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can I drink alcohol while taking LOBG M 0.5/500MG TABLET 15'S?Arrow

It is not recommended to drink alcohol while taking LOBG M 0.5/500MG TABLET 15'S, as it can lower blood sugar levels and increase the risk of other side effects.

Is LOBG M 0.5/500MG TABLET 15'S safe during pregnancy?Arrow

The safety of LOBG M 0.5/500MG TABLET 15'S during pregnancy has not been established. Therefore, it is important to talk to your doctor before taking this medication if you are pregnant or planning to become pregnant.

Is LOBG M 0.5/500MG TABLET 15'S safe during breastfeeding?Arrow

It is not known whether LOBG M 0.5/500MG TABLET 15'S passes into breast milk. Therefore, it is important to talk to your doctor before taking this medication if you are breastfeeding.

How should I store LOBG M 0.5/500MG TABLET 15'S?Arrow

Store LOBG M 0.5/500MG TABLET 15'S at room temperature, away from heat and moisture.

Are there other brands of Lornagliptin and Metformin available?Arrow

Yes, there are other brands of Lornagliptin and Metformin available. Talk to your doctor or pharmacist about which brand is best for you.

What happens if I overdose on LOBG M 0.5/500MG TABLET 15'S?Arrow

If you overdose on LOBG M 0.5/500MG TABLET 15'S, seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, diarrhea, stomach pain, and weakness.

Does LOBG M 0.5/500MG TABLET 15'S interact with other medications?Arrow

LOBG M 0.5/500MG TABLET 15'S can interact with certain other medications. Tell your doctor about all the medications you are taking, including prescription drugs, over-the-counter drugs, and herbal supplements.

Can LOBG M 0.5/500MG TABLET 15'S be used for children?Arrow

The use of LOBG M 0.5/500MG TABLET 15'S in children is not recommended as its safety and effectiveness have not been established.

References

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DrugBank: Pregabalin - Mechanism of Action, Pharmacology, Pharmacokinetics, Interactions, and more.

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PubChem: Pregabalin - Chemical Properties, Safety and Hazards, Toxicity Information, Literature, and more.

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FDA Label: Pregabalin - Full prescribing information.

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European Medicines Agency (EMA): Lyrica (pregabalin) - Summary of Product Characteristics.

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National Center for Biotechnology Information (NCBI): Efficacy and Safety of Pregabalin in the Treatment of Neuropathic Pain

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GLENMARK PHARMACEUTICALS LIMITED

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India

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