LORBRIQUA 100MG TABLET 15'S
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LORBRIQUA 100MG TABLET 15'S
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LORBRIQUA 100MG TABLET 15'S

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By PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED

MRP

156000

₹123500

20.83 % OFF

₹8233.33 Only /

Tablet

10

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Product Details
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About LORBRIQUA 100MG TABLET 15'S

  • LORBRIQUA 100MG TABLET 15'S is a medicine containing the active ingredient Lorlatinib. It is a type of targeted therapy called a tyrosine kinase inhibitor. It is used to treat a specific kind of lung cancer called metastatic non-small cell lung cancer (NSCLC). Metastatic means the cancer has spread from the lungs to other parts of the body like bones, liver, or brain. This medicine works by targeting certain changes in cancer cells to help stop them from growing and spreading.
  • While you are taking LORBRIQUA, your doctor will need to do regular checks. This includes checking your blood (like white blood cells and platelets), blood sugar, body salts (electrolytes), and how well your kidneys and liver are working. These checks help make sure the treatment is safe for you and catch any potential problems early. Like all medicines, LORBRIQUA can cause side effects. Some serious ones include effects on the liver and changes in fertility in men, which could make it harder to father a child. If you are concerned about fertility, talk to your doctor. Other side effects can include feeling tired, swelling, nerve problems, or weight gain. Always tell your doctor about *any* side effects you experience.
  • Before starting LORBRIQUA, it is important to tell your doctor about all your medical conditions. This includes if you have or have had liver problems, heart failure, high cholesterol, or high blood pressure. Also, tell your doctor right away if you get signs of an allergic reaction, like itchy skin or a rash, while taking this medicine. It is best to avoid drinking grapefruit juice while taking LORBRIQUA, as it can increase the amount of the medicine in your blood and potentially increase side effects. LORBRIQUA tablets contain lactose. If you have lactose intolerance (meaning you have trouble digesting lactose, which is found in milk), this can cause symptoms like bloating or stomach pain. Tell your doctor if you have lactose intolerance before taking this medicine. Always take LORBRIQUA exactly as your doctor tells you. Do not change your dose or stop taking it without talking to your doctor first. It is also important to tell your doctor about all other medicines you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements, as they can interact with LORBRIQUA.

Side Effects of LORBRIQUA 100MG TABLET 15'S
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Side effects are unwanted symptoms caused by medicines. When taking LORBRIQUA 100MG TABLET 15'S, you might experience side effects. While all drugs can cause side effects, not everyone gets them.

  • Cough, chest pain, or worsening of breathing problems
  • Feeling tired, faint, or losing consciousness
  • Yellowing of the skin and eyes, vomiting, abdominal pain
  • Confusion, memory loss, mood swings, difficulty speaking, seeing, or hearing things that are not real
  • Increase in cholesterol levels
  • Swelling in hand or legs
  • Double vision difficulty seeing
  • Pain, numbness, or unusual sensations (burning or pin and needles) in arms and legs, difficulty walking
  • Diarrhoea, constipation
  • Headache
  • Weight gain
  • Joint pain, muscle pain
  • Rash
  • Anaemia

Safety Advice for LORBRIQUA 100MG TABLET 15'S
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Breastfeeding Safety Icon

BreastFeeding

Unsafe

It is not known if LORBRIQUA 100MG TABLET 15'S pass into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.

Driving Safety Icon

Driving

Unsafe

It is unsafe to drive vehicles or operate heavy machinery after taking LORBRIQUA 100MG TABLET 15'S, it may cause dizziness and impair your concentration.

Liver Health Icon

Liver Function

Consult a Doctor

Inform your doctor if you have any liver problems before taking LORBRIQUA 100MG TABLET 15'S. Regular monitoring of liver function tests is recommended.

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Lungs

Consult a Doctor

Inform your doctor if you have any lung problems before taking LORBRIQUA 100MG TABLET 15'S. Consult your doctor if you have any lung diseases before starting the treatment.

Pregnancy Safety Icon

Pregnancy

Unsafe

LORBRIQUA 100MG TABLET 15'S is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of LORBRIQUA 100MG TABLET 15'S
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  • Your doctor will carefully determine the precise dose and overall treatment duration for LORBRIQUA, taking into account your specific medical condition, overall health status, and how you respond to treatment. Consistency is crucial when taking this medication, so it is absolutely essential to take your LORBRIQUA tablet at the very same time every single day. You have the flexibility to take your dose either with food or on an empty stomach, whatever is more convenient for you, unless your doctor advises otherwise. It is vital to understand that the LORBRIQUA tablet is designed to be swallowed whole. Do not chew, crush, or break the tablet, as this can alter the way the medicine is absorbed by your body and how effectively it works. Always swallow the tablet whole with a full glass of water. If you miss a dose of LORBRIQUA, do not take an extra dose to catch up. Simply skip the missed dose completely and take your next scheduled dose at your regular time. Taking a double dose is not recommended and will not improve your treatment outcome. Always follow your healthcare provider's instructions precisely regarding your LORBRIQUA dosage and schedule.

How to store LORBRIQUA 100MG TABLET 15'S?
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  • Keep LORBRIQUA 100MG TAB 1X15 away from the reach of children and pets.
  • Store LORBRIQUA 100MG TAB 1X15 at room temperature.

Benefits of LORBRIQUA 100MG TABLET 15'S
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  • Targets specific 'switches' (tyrosine kinases) in cancer cells, blocking the signals that cause them to grow uncontrollably.
  • Effectively stops cancer cell growth, survival, and spread by interrupting these key pathways.
  • Helps slow down tumor growth and can even lead to tumor shrinkage by addressing the root cause of uncontrolled cell multiplication.

How to use LORBRIQUA 100MG TABLET 15'S
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  • Your doctor has determined the specific dose and how long you should take LORBRIQUA 100MG TABLET 15'S. This decision is carefully made based on your particular health condition and other individual factors. It's crucial to follow these instructions exactly as given. Take your dose once daily. To help you remember, try to take it at the same time each day, which can be either with food or without food.
  • When taking LORBRIQUA 100MG TABLET 15'S, swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet before swallowing. This is important because the tablet is designed to work properly when taken whole.
  • Consistency is key with this medication. If you happen to forget a dose, do not worry. Simply skip the missed dose and take your next scheduled dose at its usual time. Do not try to catch up by taking two doses at once or an extra dose. Taking more than prescribed will not improve your condition faster and could increase the risk of side effects. Always consult your doctor if you have questions about your dosage or if you miss several doses. Never stop taking LORBRIQUA 100MG TABLET 15'S without first talking to your doctor.

FAQs

Can I drink alcohol while taking the LORBRIQUA 100MG TABLET 15'S?

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It is generally recommended to avoid drinking alcohol while taking LORBRIQUA 100MG TABLET 15'S, as alcohol can increase the risk of liver damage.

What should you know before taking LORBRIQUA 100MG TABLET 15'S?

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LORBRIQUA 100MG TABLET 15'S can alter cholesterol and triglyceride levels in the blood, slow down heart rate, and increase your blood pressure and glucose levels. Hence, your healthcare provider will monitor your symptoms and blood parameters before and during this treatment.

Is it safe for women of reproductive age to use the LORBRIQUA 100MG TABLET 15'S?

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For women with reproductive potential subjected to LORBRIQUA 100MG TABLET 15'S, it is advisable to discuss with your doctor the effective birth control methods (non-hormonal) during the treatment. Also, it is essential to continue birth control treatment for a minimum of 6 months after the last dose, as this medicine may impair fertility.

What should you do if you miss a dose of LORBRIQUA 100MG TABLET 15'S?

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If you miss a dose of LORBRIQUA 100MG TABLET 15'S, take it as soon as you remember. However, if your next dose is due within 4 hours, skip this dose and take your next dose at your regular time. Do not take 2 doses to make up for your missed dose.

What are the common side effects of LORBRIQUA 100MG TABLET 15'S?

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The common side effects that are likely to occur while you are on the treatment with LORBRIQUA 100MG TABLET 15'S are Swelling of arms, legs, hands and feet, numbness and tingling, weight gain, forgetfulness, confusion, tiredness, breathing difficulty, joint pain, diarrhoea, depression, irritability, high cholesterol and triglyceride levels, and cough.

When should I contact my doctor while taking LORBRIQUA 100MG TABLET 15'S?

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Contact your doctor right away if you experience problems with thinking like forgetfulness or confusion, seeing or hearing things that are not real, depression, suicidal thoughts, seizures, or changes in speech or sleep pattern.

Does LORBRIQUA 100MG TABLET 15'S interact with other medicines?

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Yes, LORBRIQUA 100MG TABLET 15'S can interact with certain other medicines. It's important to inform your doctor about all prescription and non-prescription medicines, vitamins, and herbal products you are taking to avoid potential interactions.

Is LORBRIQUA 100MG TABLET 15'S safe during pregnancy or breastfeeding?

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LORBRIQUA 100MG TABLET 15'S is not recommended during pregnancy as it may cause fetal harm. Women of reproductive age should use effective non-hormonal contraception during treatment and for at least six months after the last dose. It is not known if the medicine passes into breast milk, so breastfeeding is also not recommended during this treatment.

How does LORBRIQUA 100MG TABLET 15'S affect blood sugar and heart rate?

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LORBRIQUA 100MG TABLET 15'S can alter cholesterol and triglyceride levels, slow down heart rate, and increase blood pressure and glucose levels. Your doctor will monitor these parameters before and during treatment. Report new or worsening symptoms of high blood sugar (like increased thirst, confusion, tiredness) immediately.

Can I drive or operate machinery while taking LORBRIQUA 100MG TABLET 15'S?

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This medicine might cause breathing difficulty and problems with thinking (like forgetfulness or confusion). If you experience these side effects, it is advisable to avoid driving or operating machinery.

What is the active ingredient in LORBRIQUA 100MG TABLET 15'S?

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The active ingredient in LORBRIQUA 100MG TABLET 15'S is LORLATINIB.

What is LORBRIQUA 100MG TABLET 15'S used for?

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LORBRIQUA 100MG TABLET 15'S is an anti-cancer medicine used to treat certain types of cancer.

How does LORBRIQUA 100MG TABLET 15'S work as an anti-cancer medicine?

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As an anti-cancer medicine (Lorlatinib), LORBRIQUA 100MG TABLET 15'S works by targeting specific genetic changes in cancer cells to help stop or slow down the growth of the cancer.

References

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Pfizer Ltd

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Pfizer Ltd, Electronic medicines compendium (emc)

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Pfizer, US Food and Drug Administration

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Alice T Shaw et al; First-Line Lorlatinib or Crizotinib in Advanced ALK-Positive Lung Cancer; The New England Journal of Medicine; Published on 19/11/2020;

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Haidar El Darsa, Omar Abdel-Rahman & Randeep Sangha (2020) Pharmacological and clinical properties of lorlatinib in the treatment of ALK-rearranged advanced non-small cell lung cancer, Expert Opinion on Pharmacotherapy, 21:13, 1547-1554,

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Gafer H, de Waard Q, Compter A, van den Heuvel M. Rapid regression of neurological symptoms in patients with metastasis ALK+ lung cancer who are treated with lorlatinib: a report of two cases. BMJ Case Rep. 2019 Jul 24;12(7):e227299,

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Marketer / Manufacturer Details

PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED

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India

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LORBRIQUA 100MG TABLET 15'S

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₹123500

20.83 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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