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Content Reviewed By:
Dr. Amit Patel
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)

Allergies
Contraindicated in known allergyMacsart H must not be used in patients with a known allergy or hypersensitivity to telmisartan, hydrochlorothiazide, other sulfonamide‑derived medicines, or any of the excipients in the formulation.
MACSART H 40MG TABLET 10'S is used to treat high blood pressure in adults.
MACSART H 40MG TABLET 10'S works by relaxing blood vessels, which helps to lower blood pressure.
MACSART H 40MG TABLET 10'S should be taken as directed by a healthcare professional, typically once a day with or without food.
If a dose of MACSART H 40MG TABLET 10'S is missed, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule.
The possible side effects of MACSART H 40MG TABLET 10'S include dizziness, headache, fatigue, nausea, and low blood pressure.
Patients should speak with their healthcare professional before taking other medications with MACSART H 40MG TABLET 10'S , as it may interact with certain medications.
Patients should limit their alcohol intake while taking MACSART H 40MG TABLET 10'S , as it can increase the risk of side effects such as dizziness and low blood pressure.
MACSART H 40MG TABLET 10'S should be stored in a cool, dry place away from direct sunlight, and should be kept out of the reach of children and pets.
MACSART H 40MG TABLET 10'S may take several weeks to reach its full effect in lowering blood pressure.
Patients who experience side effects from MACSART H 40MG TABLET 10'S should speak with their healthcare professional, who may adjust the dose or switch to a different medication.
Macsart H is primarily used to treat high blood pressure (hypertension) in adults. It is usually prescribed when blood pressure is not adequately controlled with telmisartan or a similar medicine alone. By lowering blood pressure, Macsart H helps reduce the risk of complications such as heart attack, stroke, and long‑term kidney damage.
Macsart H contains telmisartan and hydrochlorothiazide. Telmisartan blocks the action of angiotensin II, a substance that tightens blood vessels, causing them to relax and widen, which lowers blood pressure. Hydrochlorothiazide is a diuretic that increases the excretion of salt and water through the kidneys, reducing blood volume and further lowering blood pressure. The combination provides a complementary effect on blood pressure control.
Macsart H must be used with caution in people with kidney problems. Both telmisartan and hydrochlorothiazide can affect kidney function and electrolyte balance. In moderate to severe kidney impairment, dose adjustments, close monitoring, or an alternative medicine may be required. In certain severe kidney conditions or in patients who cannot produce urine, this combination may be contraindicated. Always inform your doctor about any history of kidney disease before starting Macsart H, and do not start or stop it without medical advice.
Macsart H should be used carefully in patients with liver disease because telmisartan is processed in the liver and hydrochlorothiazide can alter fluid and electrolyte balance, which may be poorly tolerated in liver impairment. In mild to moderate liver dysfunction, the doctor may prescribe Macsart H with close monitoring. In severe liver disease or cholestasis, this medicine may be unsuitable or require special precautions. Patients with any history of liver problems should discuss risks and benefits with their healthcare provider before using Macsart H.
Macsart H is generally not recommended during pregnancy and is contraindicated especially in the second and third trimesters. Medicines that act on the renin–angiotensin system, such as telmisartan, can harm the developing fetus, potentially causing kidney problems, reduced amniotic fluid, skull abnormalities, or even fetal death. If you become pregnant while taking Macsart H, you should contact your doctor immediately; the medicine will usually be stopped and replaced with a safer alternative for blood pressure control during pregnancy.
Use of Macsart H during breastfeeding requires careful consideration. Hydrochlorothiazide can pass into breast milk and, at higher doses, may reduce milk production. There is limited information on the excretion of telmisartan into human breast milk, and potential effects on the nursing infant are not fully known. Because of these uncertainties, many guidelines recommend avoiding ARB‑containing combinations during breastfeeding when possible. Your doctor may choose an alternative blood pressure medicine with a better‑established safety profile in lactation, especially for newborn or premature infants.
Alcohol can enhance the blood pressure–lowering effect of Macsart H and may increase the risk of dizziness, light‑headedness, or fainting, particularly when standing up quickly. Occasional small amounts of alcohol may be tolerated in some individuals, but this should be discussed with your doctor. People with liver disease, a history of alcohol misuse, or unstable blood pressure are usually advised to avoid alcohol altogether while on Macsart H.
Macsart H can cause side effects such as dizziness, light‑headedness, fatigue, or blurred vision in some people, especially when starting treatment or after a dose change. These effects may impair your ability to drive or operate machinery safely. You should see how the medicine affects you before engaging in activities that require full alertness. If you feel dizzy or unwell, avoid driving, using tools, or operating heavy machinery and consult your doctor if symptoms persist.
If you have a history of allergy to telmisartan, hydrochlorothiazide, other sulfonamide‑derived medicines, or any component of Macsart H, you should not take this medicine. Signs of an allergic reaction can include rash, itching, swelling of the face, lips, tongue, or throat, severe dizziness, or difficulty breathing. If any of these occur after taking Macsart H, seek emergency medical help immediately. Always inform your doctor and pharmacist about all previous drug allergies before starting Macsart H.
Macsart H is often used alongside other cardiovascular medicines, but combinations must be carefully managed. Taking it with other blood pressure–lowering drugs, such as beta‑blockers, calcium channel blockers, or certain diuretics, can increase the risk of low blood pressure. Concomitant use with medicines that affect the renin–angiotensin system (like ACE inhibitors or other ARBs) or with certain potassium‑sparing diuretics and potassium supplements may increase the risk of kidney problems and abnormal potassium levels. Always provide your doctor with a complete list of your medicines so that potential interactions can be assessed and monitored.
Common side effects include dizziness, headache, tiredness, and increased urination. Because hydrochlorothiazide is a diuretic, it can cause changes in electrolytes such as sodium, potassium, and magnesium, which may lead to muscle cramps, weakness, or irregular heartbeat in more severe cases. Telmisartan may occasionally cause low blood pressure, especially in dehydrated patients or those on high doses of diuretics. Rare but serious side effects include severe allergic reactions, significant kidney dysfunction, pancreatitis, or worsening of existing liver disease. If you experience severe dizziness, fainting, difficulty breathing, swelling of the face or throat, or a marked decrease in urine output, seek medical attention immediately.
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MACLEODS PHARMACEUTICALS PRIVATE LIMITED
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