MEGASCAB LOTION 50 ML

How MEGASCAB LOTION 50 ML Works

• MEGASCAB LOTION 50 ML is a highly effective treatment for scabies and lice infestations. Its efficacy stems from the synergistic action of its key ingredients, Permethrin and Cetrimide. Permethrin, a synthetic pyrethroid, acts as a neurotoxin, disrupting the nerve cell membranes of the parasites. This disruption leads to paralysis and eventual death of the scabies mites (Sarcoptes scabiei) and lice.
• Specifically, Permethrin works by prolonging the opening of sodium channels in the nerve cells of the parasites. This causes a continuous influx of sodium ions, leading to hyperexcitation, uncontrolled muscle spasms, and ultimately, paralysis. Because mammals have a lower sensitivity to Permethrin and can efficiently metabolize it, the lotion is generally safe for human use when applied as directed.
• Cetrimide, on the other hand, is a quaternary ammonium antiseptic agent that complements Permethrin's action. It possesses antibacterial and antifungal properties, which help to prevent secondary infections that can arise from the intense itching and scratching associated with scabies and lice infestations. By reducing the bacterial load on the skin, Cetrimide promotes faster healing and reduces the risk of complications.
• The lotion formulation ensures that the active ingredients are evenly distributed across the affected skin area. Upon application, Permethrin penetrates the skin to reach the scabies mites, while Cetrimide provides surface-level disinfection. The combined effect provides comprehensive relief from the infestation and associated symptoms. The lotion base also aids in soothing the irritated skin and reducing inflammation.
• In summary, MEGASCAB LOTION 50 ML works by a dual mechanism: Permethrin paralyzes and kills scabies mites and lice by disrupting their nerve function, while Cetrimide prevents secondary infections and promotes healing through its antiseptic properties. This dual-action approach ensures effective eradication of the infestation and relief from its associated symptoms.

Common side effects of MEGASCAB LOTION 50 ML may include: itching, mild burning or stinging, dry skin, rash. Uncommon side effects may include: hair loss, skin irritation, allergic reactions (hives, swelling, difficulty breathing). Contact your doctor if you experience any severe or persistent side effects.

• If you forget to apply MEGASCAB LOTION 50 ML, use it as soon as you remember. However, if it is almost time for your next application, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

• Keep MEGASCAB LOTION 50ML away from the reach of children and pets.
• Store MEGASCAB LOTION 50ML at room temperature.

• **Understand Scabies and Its Transmission:** Scabies is caused by tiny mites that burrow under the skin, leading to intense itching, especially at night. It's highly contagious and spreads through prolonged skin-to-skin contact with an infected person. Using MEGASCAB Lotion promptly upon diagnosis helps to eliminate the mites and prevent further spread to family members or close contacts. Identifying and treating all affected individuals simultaneously is crucial for successful eradication of scabies.
• **Proper Application is Key:** Apply MEGASCAB Lotion to the entire body from the neck down to the toes, paying particular attention to areas between the fingers and toes, under the nails, wrists, armpits, genitals, and buttocks. These are common hiding spots for scabies mites. Ensure a thin, even layer of the lotion covers all skin surfaces. For infants and young children, also apply to the scalp, face, and ears, avoiding the eyes and mouth. Do not wash off the lotion before the recommended time, usually 8-14 hours, or as directed by your doctor.
• **Timing is Everything:** Apply MEGASCAB Lotion after a lukewarm bath or shower, ensuring the skin is cool and dry. This helps enhance absorption of the medication. It's best to apply the lotion at night before going to bed and leave it on overnight. After the recommended duration, wash it off thoroughly with soap and water. In some cases, your doctor may advise a second application one week later to kill any newly hatched mites.
• **Treat All Contacts and Decontaminate:** Since scabies is easily transmitted, all close contacts, including family members and sexual partners, should be treated with MEGASCAB Lotion, even if they don't have symptoms. Simultaneously, decontaminate clothing, bedding, and towels used within the past three days by washing them in hot water and drying them on high heat or dry cleaning. Items that cannot be washed can be sealed in a plastic bag for at least 72 hours. Thorough cleaning helps prevent re-infestation.
• **Manage Post-Treatment Itching:** Even after successful treatment with MEGASCAB Lotion, itching may persist for several weeks. This is due to an allergic reaction to the dead mites and their waste products under the skin. Apply soothing emollients like calamine lotion or moisturizing creams to relieve itching. Your doctor may also prescribe antihistamines or topical corticosteroids to reduce inflammation and itching. Avoid scratching, as it can lead to skin irritation and secondary infections. If itching persists or worsens despite these measures, consult your doctor for further evaluation.

• There are no known food interactions with MEGASCAB LOTION 50 ML. It is a topical medication, and its absorption into the bloodstream is minimal. Therefore, it is unlikely to be affected by food intake. You can continue your regular diet while using this medication unless otherwise directed by your doctor.