MET XL R 25/5MG TABLET 15'S

How MET XL R 25/5MG TABLET 15'S Works

• MET XL R 25/5MG TABLET 15'S is a combination medication containing Metoprolol and Ramipril, designed to manage hypertension (high blood pressure) and reduce the risk of cardiovascular events. Each component works through different mechanisms to achieve its therapeutic effect.
• Metoprolol, a beta-blocker, primarily targets the beta-1 adrenergic receptors in the heart. By blocking these receptors, Metoprolol slows down the heart rate and reduces the force of heart muscle contractions. This leads to a decrease in cardiac output, which is the amount of blood the heart pumps per minute. Consequently, blood pressure is lowered, and the heart's workload is reduced. This action is particularly beneficial in individuals with conditions like angina (chest pain) and heart failure, as it improves the heart's efficiency and oxygen demand.
• Ramipril, on the other hand, is an ACE (Angiotensin-Converting Enzyme) inhibitor. ACE is an enzyme in the body that converts angiotensin I to angiotensin II, a potent vasoconstrictor (a substance that narrows blood vessels). By inhibiting ACE, Ramipril prevents the formation of angiotensin II, leading to vasodilation (widening of blood vessels). This reduces peripheral resistance, allowing blood to flow more easily and lowering blood pressure. Additionally, Ramipril increases levels of bradykinin, a peptide that also promotes vasodilation.
• The combined action of Metoprolol and Ramipril provides a synergistic effect in managing hypertension. Metoprolol reduces cardiac output, while Ramipril reduces peripheral resistance. This dual mechanism effectively lowers blood pressure and reduces the strain on the cardiovascular system. Furthermore, Ramipril has been shown to have protective effects on the kidneys and heart, making it beneficial for individuals with diabetes or other conditions that increase the risk of cardiovascular complications.
• In summary, MET XL R 25/5MG TABLET 15'S works by combining the beta-blocking effects of Metoprolol to reduce heart rate and cardiac output with the ACE-inhibiting effects of Ramipril to dilate blood vessels and reduce peripheral resistance. This combination effectively lowers blood pressure and protects the heart and kidneys, thereby reducing the risk of cardiovascular events such as heart attack and stroke. Always take this medication as prescribed by your healthcare provider for optimal results.

Common side effects of MET XL R 25/5MG TABLET may include: Headache, Dizziness, Fatigue, Slow heart rate, Nausea, Vomiting, Diarrhea, Constipation, Cold extremities (hands and feet), Low blood pressure, Shortness of breath. Uncommon side effects may include: Sleep disturbances, Depression, Dry mouth, Visual disturbances, Skin rash, Hair loss, Muscle cramps, Increased sweating, Allergic reactions. Rare side effects may include: Liver problems, Changes in blood sugar levels, Confusion, Memory problems, Worsening of asthma, Erectile dysfunction.

• If you miss a dose of MET XL R 25/5MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep MET XL R 25/5MG TAB 1X15 away from the reach of children and pets.
• Store MET XL R 25/5MG TAB 1X15 at room temperature.

• Take MET XL R 25/5MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting your healthcare provider. Sudden discontinuation can lead to serious complications.
• This medicine is typically taken once daily, preferably with or immediately after a meal. Taking it with food can help reduce the likelihood of stomach upset and improve absorption.
• MET XL R 25/5MG TABLET 15'S is a combination medication used to treat hypertension (high blood pressure). It combines a beta-blocker (Metoprolol) and a calcium channel blocker (Rilmenidine). It's crucial to monitor your blood pressure regularly while taking this medication and keep a record for your doctor.
• Be aware of potential side effects, such as dizziness, fatigue, headache, slow heartbeat, or cold extremities. If you experience any persistent or bothersome side effects, inform your doctor promptly. Do not drive or operate heavy machinery if you feel dizzy or lightheaded.
• Inform your doctor about all other medications, supplements, or herbal products you are taking, as they may interact with MET XL R 25/5MG TABLET 15'S. Pay special attention to other blood pressure medications, heart medications, or antidepressants.
• If you have diabetes, monitor your blood sugar levels regularly, as beta-blockers can mask the symptoms of hypoglycemia (low blood sugar). Report any unusual changes in blood sugar to your doctor.
• Avoid excessive alcohol consumption while taking this medicine, as it can further lower your blood pressure and increase the risk of side effects like dizziness.
• Store MET XL R 25/5MG TABLET 15'S at room temperature, away from moisture and heat. Keep it out of reach of children and pets.
• If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• Attend all scheduled follow-up appointments with your doctor to monitor your progress and adjust your treatment plan as needed.

• MET XL R 25/5MG TABLET 15'S can be taken with or without food, but it is advisable to take it at a consistent time each day. Avoid consuming large amounts of alcohol while taking this medication, as it may increase the risk of side effects.