MIGREST TABLET 15'S

How MIGREST TABLET 15'S Works

• MIGREST TABLET 15'S is a combination medicine formulated to provide relief from migraine headaches. Its effectiveness stems from the synergistic action of its key ingredients: Flunarizine and Propranolol.
• Flunarizine, a calcium channel blocker, plays a crucial role in preventing migraine attacks. Migraines are often associated with changes in blood vessel tone in the brain. Flunarizine works by inhibiting the entry of calcium ions into nerve and muscle cells. This action leads to the stabilization of blood vessels in the brain, preventing excessive constriction or dilation that can trigger a migraine. By reducing the frequency and intensity of these vascular changes, Flunarizine helps to decrease the likelihood of migraine occurrence. Moreover, it exhibits antihistamine properties, which may further contribute to its migraine-preventive effects. Essentially, it helps to normalize the blood flow and neuronal excitability within the brain, creating a more stable environment less prone to migraine triggers.
• Propranolol, a beta-blocker, complements Flunarizine's action by addressing other physiological factors contributing to migraines. Propranolol works by blocking the effects of certain natural chemicals in your body, such as epinephrine (adrenaline), on the heart and blood vessels. By blocking beta-adrenergic receptors, Propranolol helps to reduce heart rate, lower blood pressure, and decrease the force of heart muscle contraction. This action reduces the overall excitability of the cardiovascular system, making it less responsive to stress and anxiety, which are common migraine triggers. Furthermore, Propranolol can also affect neurotransmitter activity in the brain, potentially influencing the pathways involved in migraine development. It is thought to stabilize nerve activity and reduce the likelihood of the neuronal firing patterns that lead to migraine pain. Essentially, it calms down the body's response to stress and regulates nerve signals that can initiate a migraine.
• The combined action of Flunarizine and Propranolol provides a comprehensive approach to migraine prophylaxis. Flunarizine stabilizes blood vessels and neuronal excitability in the brain, while Propranolol reduces cardiovascular excitability and modulates neurotransmitter activity. Together, they work to address both the vascular and neurological components of migraine, leading to a reduction in the frequency, duration, and severity of migraine attacks. This combination allows for a more balanced and effective approach to migraine management compared to using either medication alone. It's important to note that MIGREST TABLET 15'S is intended for migraine prevention and should be taken regularly as prescribed by a healthcare professional to achieve optimal results. It is not designed to treat acute migraine attacks.
• In summary, MIGREST TABLET 15'S works by utilizing Flunarizine to stabilize blood vessels and reduce neuronal excitability, and Propranolol to decrease cardiovascular excitability and modulate nerve signals, ultimately reducing the occurrence and intensity of migraines.

MIGREST TABLET 15'S may cause several side effects, although not everyone experiences them. Common side effects include: * Nausea * Vomiting * Dizziness * Drowsiness * Dry mouth * Fatigue * Muscle weakness Less common but potentially serious side effects include: * Allergic reactions (rash, itching, swelling, difficulty breathing) * Changes in blood pressure (either high or low) * Heart palpitations * Visual disturbances * Seizures * Liver problems (abdominal pain, jaundice, dark urine) * Serotonin syndrome (confusion, agitation, muscle twitching, sweating, rapid heartbeat) - especially if taken with other serotonergic drugs * Increased risk of bleeding or bruising This is not an exhaustive list, and other side effects may occur. If you experience any unusual symptoms while taking MIGREST TABLET 15'S, consult your doctor immediately.

• If you miss a dose of Migrest Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep MIGREST TAB 1X15 away from the reach of children and pets.
• Store MIGREST TAB 1X15 at room temperature.

• Take Migrest Tablet exactly as prescribed by your doctor. Do not exceed the recommended dosage or frequency. Taking more than prescribed will not alleviate your migraine faster and may increase the risk of side effects.
• Migrest Tablet is most effective when taken at the first sign of a migraine. Keep a record of your migraine triggers and symptoms to help you recognize an attack early. This medicine is not for daily preventive use.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking. Certain medications can interact with Migrest Tablet, increasing the risk of side effects or decreasing its effectiveness. Pay close attention to medications for depression or anxiety.
• If you experience persistent or worsening side effects such as nausea, dizziness, drowsiness, or chest pain, consult your doctor immediately. Do not drive or operate heavy machinery until you know how Migrest Tablet affects you. Rest in a quiet, dark room to help alleviate migraine symptoms.
• Store Migrest Tablet at room temperature away from moisture and heat. Keep out of reach of children and pets. Properly dispose of any unused medication according to local regulations. Do not flush down the toilet.
• Avoid food items like aged cheese, processed meat, chocolates & alcohol which are known trigger for migraine. Also, keep yourself hydrated & avoid stress to prevent migraine attack. Regular exercise & sleep can help reduce the frequency of attacks.

• It is advisable to take Migrest Tablet 15's after food to prevent stomach upset.