NEXITO LS TABLET 10'S
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NEXITO LS TABLET 10'S

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NEXITO LS TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

165.93

₹141.04

15 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About NEXITO LS TABLET 10'S

  • Nexito LS Tablet is a carefully formulated combination medicine used to relieve the symptoms of depression and anxiety, bringing together two active ingredients: escitalopram, a selective serotonin reuptake inhibitor (SSRI), and clonazepam, a benzodiazepine. Escitalopram works by increasing levels of serotonin, a natural brain chemical that helps maintain mental balance, while clonazepam enhances the effect of gamma-aminobutyric acid (GABA), a messenger that suppresses excessive brain activity to promote calmness and relaxation.
  • This synergistic action allows Nexito LS to address a broad range of symptoms seen in depression and anxiety disorders. It can help ease feelings of sadness, hopelessness and worthlessness while also relieving the excessive worry, fear and tension of anxiety. By restoring the balance of neurotransmitters in the brain, it supports emotional stability and helps improve overall mood, making it useful when anxiety and low mood occur together.
  • Nexito LS is typically prescribed for the short-term management of anxiety disorders or as an add-on treatment for depression, often when quicker relief of anxiety is needed alongside longer-acting antidepressant therapy. It is important to take it exactly as prescribed; the strength and duration depend on the severity of your condition and how you respond. Do not stop taking it abruptly, as this can cause withdrawal symptoms — always consult your healthcare provider before making any change to your regimen.
  • Before starting, tell your doctor about any pre-existing medical conditions, allergies or other medicines you are taking, so it can be used safely and effectively. Common side effects may include drowsiness, dizziness, nausea and dry mouth; if these persist or become bothersome, consult your doctor. While on Nexito LS it is important to avoid alcohol and other central nervous system depressants, which can worsen sedation and other side effects.
  • Used under the guidance of a qualified healthcare professional, Nexito LS offers a comprehensive way to manage depression with prominent anxiety, combining the mood-lifting benefit of escitalopram with the calming, anti-anxiety effect of clonazepam to help restore emotional well-being and quality of life. Report any unusual mood changes, worsening depression or thoughts of self-harm to your doctor promptly, and keep the medicine out of the reach of children.
  • Generic alternative: a generic medicine has the same active composition as the branded product — for Nexito LS Tablet 10's that is Escitalopram Oxalate 10 Mg+clonazepam 0.25 MG. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of NEXITO LS TABLET 10'S

  • Depression
  • Anxiety disorder
  • Social anxiety disorder
  • Panic disorder
  • Obsessive-compulsive disorder (OCD)

How NEXITO LS TABLET 10'S Works

  • NEXITO LS TABLET 10'S is a combination medication designed to address symptoms of depression and anxiety by targeting multiple neurotransmitter systems in the brain. It contains two active ingredients: Escitalopram and Levosulpiride. Escitalopram is a selective serotonin reuptake inhibitor (SSRI), while Levosulpiride is an atypical antipsychotic with prokinetic properties.
  • Escitalopram primarily works by increasing the levels of serotonin, a neurotransmitter responsible for regulating mood, emotions, and sleep. Serotonin is released by nerve cells in the brain and then reabsorbed. Escitalopram blocks this reabsorption process, allowing more serotonin to remain available in the synaptic cleft (the space between nerve cells). This enhanced serotonin activity helps to alleviate symptoms of depression and anxiety by improving mood, reducing feelings of sadness or hopelessness, and promoting a sense of well-being.
  • Levosulpiride, on the other hand, exerts its effects through different mechanisms. It acts as a dopamine receptor antagonist, primarily blocking D2 dopamine receptors in the brain and gastrointestinal tract. By blocking dopamine receptors in the brain, Levosulpiride can help to improve mood and reduce anxiety symptoms. Additionally, its prokinetic properties stimulate gastrointestinal motility, which can be beneficial for individuals experiencing gastrointestinal disturbances related to anxiety or depression, such as nausea, bloating, or constipation. This dual action helps in comprehensive management of the condition.
  • In summary, NEXITO LS TABLET 10'S works by combining the antidepressant effects of Escitalopram (increasing serotonin levels) with the anxiolytic and prokinetic effects of Levosulpiride (blocking dopamine receptors and promoting gastrointestinal motility). This synergistic action can provide more effective relief from the symptoms of depression and anxiety compared to using either medication alone. It's important to take this medication as prescribed by your doctor, and to be aware of potential side effects.
  • The combination of Escitalopram and Levosulpiride in NEXITO LS provides a multi-faceted approach. Escitalopram elevates serotonin, improving mood regulation and reducing depressive symptoms. Simultaneously, Levosulpiride helps manage anxiety and related gastrointestinal issues by modulating dopamine activity and enhancing digestive function. This combined action can lead to a more comprehensive and effective treatment outcome for patients experiencing both depression and anxiety, addressing both psychological and physical symptoms that often accompany these conditions. Always consult with a healthcare professional for personalized medical advice and treatment.

Side Effects of NEXITO LS TABLET 10'SArrow

Common side effects of Nexito LS Tablet may include nausea, constipation, vomiting, diarrhea, dry mouth, increased sweating, fatigue, drowsiness, insomnia (difficulty sleeping), anxiety, restlessness, decreased appetite, weight changes, blurred vision, dizziness, and sexual dysfunction (decreased libido, ejaculatory problems, erectile dysfunction). Uncommon side effects can include muscle pain or cramps, tremor, urinary retention, confusion, agitation, changes in heart rhythm (palpitations), increased blood pressure, and allergic reactions (rash, itching, swelling). Rare but serious side effects can include serotonin syndrome (symptoms include high fever, agitation, confusion, tremors, and rapid heart rate), neuroleptic malignant syndrome (symptoms include fever, muscle rigidity, altered mental status, and autonomic dysfunction), seizures, and suicidal thoughts or behavior. This is not an exhaustive list; other side effects may occur. Consult your doctor if you experience any concerning symptoms.

  • Nexito LS, side effects, nausea, constipation, vomiting, diarrhea, dry mouth, sweating, fatigue, drowsiness, insomnia, anxiety, restlessness, appetite, weight changes, blurred vision, dizziness, sexual dysfunction, muscle pain, cramps, tremor, urinary retention, confusion, agitation, palpitations, blood pressure, allergic reactions, serotonin syndrome, neuroleptic malignant syndrome, seizures, suicidal thoughts

Safety Advice for NEXITO LS TABLET 10'SArrow

alcohol

Alcohol

Alcohol

It is unsafe to consume NEXITO LS TABLET 10'S with alcohol.

pregnancy

Pregnancy

Pregnancy

NEXITO LS TABLET 10'S is unsafe to use during pregnancy.

breast_feeding

BreastFeeding

BreastFeeding

NEXITO LS TABLET 10'S is probably safe to use during breastfeeding.

driving

Driving

Driving

NEXITO LS TABLET 10'S may cause dizziness, sleepiness, or impair your vision.

kidney

Kidney Function

Kidney Function

NEXITO LS TABLET 10'S should be used with caution in patients with kidney disease. Dose adjustment may be needed. Please consult your doctor.

liver

Liver Function

Liver Function

NEXITO LS TABLET 10'S should be used with caution in patients with liver disease. Dose adjustment may be needed. Please consult your doctor.

allergies

Allergies

Allergies

Inform your doctor if you are allergic to NEXITO LS TABLET 10'S.

Dosage of NEXITO LS TABLET 10'SArrow

  • The recommended dosage of 'NEXITO LS TABLET 10'S' varies depending on individual patient needs, the severity of the condition being treated, and the patient's response to the medication. It is crucial to adhere strictly to the dosage prescribed by your physician. Typically, 'NEXITO LS TABLET 10'S' is administered orally, once daily. The starting dose is generally low and may be gradually increased by your doctor to achieve the desired therapeutic effect. This titration process helps minimize potential side effects and ensures optimal efficacy.
  • The tablets should be swallowed whole with a glass of water, preferably at the same time each day. Consistency in timing helps maintain a stable level of medication in your body. 'NEXITO LS TABLET 10'S' can be taken with or without food, but maintaining a consistent pattern relative to meals is advisable. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Your doctor will determine the appropriate duration of treatment with 'NEXITO LS TABLET 10'S'. It is essential to continue taking the medication for the entire prescribed period, even if you start feeling better. Abruptly discontinuing 'NEXITO LS TABLET 10'S' can lead to withdrawal symptoms. If you need to stop the medication, your doctor will gradually reduce the dosage to minimize these effects. Regular follow-up appointments with your doctor are necessary to monitor your progress and adjust the dosage as needed. Inform your doctor about any other medications you are taking, as they may interact with 'NEXITO LS TABLET 10'S'.
  • Take 'NEXITO LS TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of NEXITO LS TABLET 10'S?Arrow

  • If you miss a dose of NEXITO LS Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store NEXITO LS TABLET 10'S?Arrow

  • Keep NEXITO LS TAB 1X10 away from the reach of children and pets.
  • Store NEXITO LS TAB 1X10 at room temperature.

Benefits of NEXITO LS TABLET 10'SArrow

  • NEXITO LS TABLET 10'S offers a comprehensive approach to managing symptoms of depression and anxiety, providing relief and improving overall mental well-being. It combines the selective serotonin reuptake inhibitor (SSRI) escitalopram with the anxiolytic agent clonazepam to address both the underlying causes and immediate symptoms of these conditions.
  • Escitalopram, the SSRI component, works by increasing the levels of serotonin in the brain. Serotonin is a neurotransmitter that plays a crucial role in regulating mood, sleep, appetite, and other functions. By preventing the reuptake of serotonin, escitalopram ensures that more of this neurotransmitter is available to bind to receptors in the brain, thereby improving mood and reducing feelings of sadness, hopelessness, and worthlessness associated with depression.
  • Clonazepam, on the other hand, is a benzodiazepine that acts on the central nervous system to produce a calming effect. It enhances the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits nerve activity in the brain. By increasing GABA activity, clonazepam helps to reduce anxiety, tension, and panic attacks, providing rapid relief from these distressing symptoms. This makes NEXITO LS particularly effective in managing anxiety disorders, including generalized anxiety disorder, social anxiety disorder, and panic disorder.
  • The combination of escitalopram and clonazepam in NEXITO LS TABLET 10'S offers several advantages. Firstly, it addresses both the mood symptoms of depression and the anxiety symptoms that often accompany it. Secondly, it provides both short-term relief from anxiety and long-term improvement in mood. Clonazepam provides rapid relief from anxiety, while escitalopram gradually builds up in the system to provide sustained improvement in mood over time.
  • Furthermore, NEXITO LS TABLET 10'S can improve sleep quality, as both escitalopram and clonazepam can have sedative effects. This can be particularly beneficial for individuals who experience insomnia or other sleep disturbances due to depression or anxiety.
  • NEXITO LS TABLET 10'S can lead to improved social functioning. By reducing anxiety and improving mood, individuals may feel more confident and comfortable in social situations, leading to improved relationships and increased participation in social activities.
  • In summary, NEXITO LS TABLET 10'S offers a multifaceted approach to managing depression and anxiety by targeting both mood and anxiety symptoms, providing rapid relief and long-term improvement, improving sleep quality, and enhancing social functioning. It is important to use this medication under the guidance of a healthcare professional to ensure safe and effective treatment.

How to use NEXITO LS TABLET 10'SArrow

  • NEXITO LS TABLET 10'S should be taken orally, exactly as prescribed by your doctor. It is typically recommended to take this medication once daily, with or without food. However, consistency is key, so try to take it at the same time each day to maintain a steady level of the medicine in your system. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water.
  • The dosage of NEXITO LS TABLET 10'S will vary depending on your individual condition, its severity, and your response to treatment. Your doctor will determine the most appropriate dose for you. It's crucial not to adjust the dosage yourself, even if you feel better or worse. Always follow your doctor's instructions precisely.
  • Continue taking NEXITO LS TABLET 10'S for the entire duration prescribed by your doctor, even if you start to feel better. Do not stop taking the medication abruptly without consulting your doctor, as this can lead to withdrawal symptoms or a worsening of your condition. If you need to stop the medication, your doctor will gradually reduce the dose over time to minimize any potential side effects.
  • If you miss a dose of NEXITO LS TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
  • Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting NEXITO LS TABLET 10'S. Certain medications can interact with NEXITO LS TABLET 10'S, potentially affecting its effectiveness or increasing the risk of side effects. If you experience any unusual or bothersome side effects while taking NEXITO LS TABLET 10'S, contact your doctor immediately.
  • Store NEXITO LS TABLET 10'S at room temperature, away from heat, light, and moisture. Keep the medication out of the reach of children and pets.

Quick Tips for NEXITO LS TABLET 10'SArrow

  • Take NEXITO LS TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting them, even if you feel better. This medication is usually taken once daily, with or without food, preferably at the same time each day to maintain consistent blood levels.
  • NEXITO LS TABLET 10'S contains escitalopram and clonazepam, which can cause drowsiness or dizziness. Avoid driving, operating heavy machinery, or performing tasks that require alertness until you know how this medication affects you. Be cautious when standing up quickly from a sitting or lying position to minimize dizziness.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting NEXITO LS TABLET 10'S. This is crucial to avoid potential drug interactions. Pay special attention to other medications that also cause drowsiness or affect serotonin levels.
  • Alcohol can increase the sedative effects of NEXITO LS TABLET 10'S. It is strongly advised to avoid or limit alcohol consumption while taking this medication to prevent excessive drowsiness and impaired coordination. The combination can also increase the risk of adverse effects.
  • If you miss a dose of NEXITO LS TABLET 10'S, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Sudden discontinuation of this medication can lead to withdrawal symptoms; therefore, consult your doctor before stopping the medication.

Food Interactions with NEXITO LS TABLET 10'SArrow

  • NEXITO LS TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent medicine levels in the body.

FAQs

What is Nexito LS Tablet 10's?Arrow

Nexito LS Tablet 10's is a medication used to treat depression and anxiety disorders. It contains a combination of Escitalopram and Clonazepam.

What are the uses of Nexito LS Tablet 10's?Arrow

Nexito LS Tablet 10's is used to treat depression, anxiety disorders, panic disorder, and social anxiety disorder.

How does Nexito LS Tablet 10's work?Arrow

Nexito LS Tablet 10's works by increasing the levels of certain chemical messengers in the brain that help maintain mental balance. Escitalopram is a selective serotonin reuptake inhibitor (SSRI), and Clonazepam is a benzodiazepine.

What are the common side effects of Nexito LS Tablet 10's?Arrow

Common side effects of Nexito LS Tablet 10's include nausea, vomiting, diarrhea, constipation, changes in appetite, weight changes, dizziness, drowsiness, and decreased sexual function.

What should be the dosage of Nexito LS Tablet 10's?Arrow

The dosage of Nexito LS Tablet 10's should be as prescribed by the doctor. It is usually taken once a day.

Is Nexito LS Tablet 10's addictive?Arrow

Clonazepam, a component of Nexito LS Tablet 10's, can be addictive. Therefore, it should only be taken as prescribed by the doctor.

Can I take Nexito LS Tablet 10's with alcohol?Arrow

Taking Nexito LS Tablet 10's with alcohol can increase side effects such as drowsiness and dizziness. Therefore, it should be avoided.

Is Nexito LS Tablet 10's safe during pregnancy?Arrow

The safety of Nexito LS Tablet 10's during pregnancy has not been established. Therefore, it should only be taken during pregnancy if clearly needed and prescribed by the doctor.

Is Nexito LS Tablet 10's safe during breastfeeding?Arrow

Nexito LS Tablet 10's may pass into breast milk and harm the baby. Therefore, you should consult your doctor before taking it while breastfeeding.

What happens if I miss a dose of Nexito LS Tablet 10's?Arrow

If you miss a dose of Nexito LS Tablet 10's, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

How to store Nexito LS Tablet 10's?Arrow

Store Nexito LS Tablet 10's at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

Are there any alternatives available to Nexito LS Tablet 10's?Arrow

Yes, there are many other medications available in the market that are used to treat depression and anxiety disorders. Talk to your doctor so they can find the best option for you.

Does Nexito LS Tablet 10's cause weight gain?Arrow

Nexito LS Tablet 10's can cause weight gain in some people. If you are concerned about this, talk to your doctor.

What should I avoid while taking Nexito LS Tablet 10's?Arrow

While taking Nexito LS Tablet 10's, avoid drinking alcohol, operating machinery, or performing tasks that require alertness, as it can cause drowsiness.

Can I stop taking Nexito LS Tablet 10's abruptly?Arrow

Nexito LS Tablet 10's should not be stopped abruptly as it can cause withdrawal symptoms. Talk to your doctor about gradually reducing the dosage.

What is Nexito LS Tablet 10's used for?Arrow

Nexito LS Tablet 10's is used for certain seizure disorders; panic disorder; some movement disorders — under specialist direction; and major depressive disorder; generalised anxiety disorder; panic disorder; some other anxiety conditions. Nexito LS Tablet 10's contains Clonazepam 0.25 MG + Escitalopram Oxalate 10 MG. Always use Nexito LS Tablet 10's as advised by your doctor.

What is the composition of Nexito LS Tablet 10's?Arrow

Nexito LS Tablet 10's contains Clonazepam 0.25 MG + Escitalopram Oxalate 10 MG. It is a benzodiazepine anticonvulsant/anxiolytic; and SSRI antidepressant.

What are the side effects of Nexito LS Tablet 10's?Arrow

Commonly reported side effects of Nexito LS Tablet 10's include drowsiness, fatigue, unsteadiness, poor coordination, memory and concentration problems, behavioural changes; and nausea, sleep disturbance, drowsiness, sweating, sexual dysfunction, dry mouth, reduced appetite. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Nexito LS Tablet 10's?Arrow

Nexito LS Tablet 10's is listed at Rs. 141.04 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Nexito LS Tablet 10's?Arrow

Prescription-only and controlled; and Increased suicidal thinking in children, adolescents and young adults — close monitoring early in treatment and after dose changes. Tell your doctor about all other medicines you take before starting Nexito LS Tablet 10's.

What is the correct dosage of Nexito LS Tablet 10's?Arrow

The dose of Nexito LS Tablet 10's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Nexito LS Tablet 10's?Arrow

A generic medicine is one with the same active composition as the branded product — for Nexito LS Tablet 10's that is Clonazepam 0.25 MG + Escitalopram Oxalate 10 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Nexito LS Tablet 10's.

Is Nexito LS Tablet 10's a prescription medicine?Arrow

Yes. Nexito LS Tablet 10's requires a valid doctor's prescription.

Who is the manufacturer of Nexito LS Tablet 10's?Arrow

Nexito LS Tablet 10's is manufactured by Sun Pharmaceutical Industries Ltd.

What is the dosage form of Nexito LS Tablet 10's?Arrow

Nexito LS Tablet 10's is supplied as a tablet and is taken by the oral route.

What are the benefits of Nexito LS Tablet 10's?Arrow

Nexito LS Tablet 10's contains Clonazepam 0.25 MG + Escitalopram Oxalate 10 MG. It is used for certain seizure disorders; panic disorder; some movement disorders — under specialist direction; and major depressive disorder; generalised anxiety disorder; panic disorder; some other anxiety conditions. The benefit you get depends on the condition your doctor prescribed Nexito LS Tablet 10's for.

Is Nexito LS Tablet 10's safe to take daily?Arrow

Whether Nexito LS Tablet 10's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Nexito LS Tablet 10's on your own.

When should Nexito LS Tablet 10's be taken — morning or night?Arrow

The timing of Nexito LS Tablet 10's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Nexito LS Tablet 10's without a doctor's consultation?Arrow

No. Nexito LS Tablet 10's is a prescription medicine and should only be taken on a doctor's advice.

Can Nexito LS Tablet 10's be taken during pregnancy or breastfeeding?Arrow

Do not take Nexito LS Tablet 10's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

Can I drink alcohol while taking Nexito LS Tablet 10's?Arrow

Check with your doctor before drinking alcohol while taking Nexito LS Tablet 10's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.

How should Nexito LS Tablet 10's be stored?Arrow

Store Nexito LS Tablet 10's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

Book Icon

PubChem is a database of chemical molecules and their activities against biological assays.

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DrugBank is a comprehensive, freely accessible, online database containing information on drugs, drug targets, and drug action.

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Escitalopram information from DrugBank.

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FDA's Drugs@FDA database for approved drug products.

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European Medicines Agency (EMA) for information on medicines approved in Europe.

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PubMed Central: free archive of biomedical and life sciences literature.

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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