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NEXOVAS T TABLET 10'S

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NEXOVAS T TABLET 10'S

By MACLEODS PHARMACEUTICALS PRIVATE LIMITED

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Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About NEXOVAS T TABLET 10'S

  • Nexovas T is a prescription-only fixed-dose combination medicine that contains cilnidipine and telmisartan. It is generally used for the management of high blood pressure (essential hypertension) in adults when treatment with a single medicine is not sufficient to control blood pressure adequately. Cilnidipine is a calcium channel blocker (specifically a dihydropyridine calcium channel antagonist with additional N-type calcium channel blocking activity), while telmisartan is an angiotensin II receptor blocker (ARB). By combining these two mechanisms, Nexovas T helps relax and widen blood vessels, reduce vascular resistance, and lower blood pressure in a sustained manner over 24 hours. Lowering elevated blood pressure reduces the risk of serious cardiovascular events such as stroke, heart attack, heart failure, and kidney damage when used as part of a comprehensive risk-reduction strategy that may also include lifestyle changes. Nexovas T is usually taken once daily at the same time each day, with or without food, as directed by a registered medical practitioner. The exact strength and regimen are individualized based on the patient’s blood pressure readings, associated medical conditions, and response to therapy. The tablet should be swallowed whole with water and not crushed or chewed unless a healthcare professional specifically advises otherwise. Nexovas T is not intended for immediate relief of acute hypertensive emergencies. It is used as a long-term maintenance therapy and should be continued regularly, even if the patient feels well, because high blood pressure often has no symptoms. Abrupt discontinuation without medical advice may lead to uncontrolled blood pressure and increased cardiovascular risk. Commonly reported adverse effects with cilnidipine–telmisartan combinations may include dizziness, light-headedness (especially when standing up quickly), headache, flushing, ankle or leg swelling, fatigue, palpitations, and mild gastrointestinal symptoms such as nausea or abdominal discomfort. Some patients may experience increased urination or a feeling of weakness at the start of therapy, which is often transient. More serious but less common adverse effects can include significant drop in blood pressure, worsening kidney function, changes in serum potassium levels (hyperkalaemia), or allergic reactions such as rash, itching, or facial swelling. Any unusual or severe symptom should be promptly reported to a doctor. Nexovas T is generally not recommended during pregnancy, particularly in the second and third trimesters, because ARBs like telmisartan can cause serious harm to the developing fetus, including kidney damage and reduced amniotic fluid. It is also usually avoided during breastfeeding unless the potential benefit clearly outweighs the potential risk, and an alternative medicine with a better-established safety profile is not suitable. Patients with severe liver or kidney impairment, bilateral renal artery stenosis, a history of angioedema related to ARBs or ACE inhibitors, or very low baseline blood pressure require special caution and close monitoring. Before starting Nexovas T, patients should inform their doctor about all existing medical conditions, including heart failure, coronary artery disease, stroke history, diabetes, kidney or liver disease, and any history of electrolyte disturbances. They should also provide a complete list of all medicines, herbal products, and supplements they are taking, as telmisartan and cilnidipine can interact with other drugs such as potassium-sparing diuretics, potassium supplements, certain painkillers (NSAIDs), and other antihypertensives. Regular monitoring of blood pressure, kidney function, and electrolytes is recommended during therapy. Nexovas T should always be used under medical supervision and in accordance with local prescribing information.

Uses of NEXOVAS T TABLET 10'S

  • Is used in the treatment of Hypertension(high blood pressure)
  • Is used in the prevention of Heart Attack
  • Is used in the prevention of Stroke
  • Is used in the prevention of Heart Failure

How NEXOVAS T TABLET 10'S Works

  • NEXOVAS T TABLET 10'S is a combination medication that contains two active ingredients - Telmisartan and Cilnidipine. These two drugs work in different ways to lower blood pressure and improve cardiovascular health.
  • This makes NEXOVAS T TABLET 10'S an effective treatment option for patients with hypertension who do not respond well to treatment with a single medication.

Safety Advice for NEXOVAS T TABLET 10'SArrow

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Other medical conditions and drug interactions

Inform your doctor about all conditions and medicines

Patients with heart failure, coronary artery disease, cerebrovascular disease, diabetes, or significant electrolyte disturbances should use Nexovas T under close medical supervision.

What if I miss my dose of NEXOVAS T TABLET 10'S?Arrow

  • If you miss a dose of NEXOVAS T TABLET 10'S , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

How to store NEXOVAS T TABLET 10'S?Arrow

  • Keep NEXOVAS T TAB 1X10 away from the reach of children and pets.
  • Store NEXOVAS T TAB 1X10 at room temperature.

Benefits of NEXOVAS T TABLET 10'SArrow

  • NEXOVAS T TABLET 10'S is an effective medication for the treatment of hypertension or high blood pressure, which can help to reduce the risk of complications such as heart attacks, strokes, and kidney damage.
  • The combination of Telmisartan and Cilnidipine in NEXOVAS T TABLET 10'S may be more effective in lowering blood pressure than either medication alone, especially for patients who do not respond well to treatment with a single medication.
  • By relaxing blood vessels and lowering blood pressure, NEXOVAS T TABLET 10'S can improve blood flow throughout the body, reducing the workload on the heart and improving overall cardiovascular health.
  • NEXOVAS T TABLET 10'S can also help to protect the kidneys from damage caused by high blood pressure, which is a common complication of hypertension.
  • The medication is available in the form of tablets that are easy to take, making it a convenient option for patients with hypertension who need to take medication regularly.
  • NEXOVAS T TABLET 10'S may also have other health benefits, such as reducing inflammation and improving insulin sensitivity, although further research is needed to confirm these effects.
  • By reducing blood pressure and improving cardiovascular health, NEXOVAS T TABLET 10'S may help to improve quality of life for patients with hypertension, reducing symptoms such as fatigue, dizziness, and shortness of breath.
  • NEXOVAS T TABLET 10'S is a prescription medication that should only be taken under the supervision of a healthcare professional, ensuring that patients receive the right dose and are monitored for any potential side effects or interactions with other medications.

How to use NEXOVAS T TABLET 10'SArrow

  • NEXOVAS T TABLET 10'S is a prescription medication, and should only be taken under the supervision of a healthcare professional.
  • The usual dose of NEXOVAS T TABLET 10'S is one tablet taken orally, usually once a day, with or without food.
  • It is important to take the medication at the same time each day to ensure that the level of medication in the blood remains consistent.
  • Swallow the tablet whole with a glass of water. Do not crush or chew the tablet, as this may affect its effectiveness.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
  • Do not take a double dose to make up for a missed dose.
  • It may take several weeks of regular use for the full benefit of NEXOVAS T TABLET 10'S to be seen. Do not stop taking the medication without first consulting with your doctor, even if you feel well.
  • It is important to continue taking the medication even if you feel well, as hypertension often has no symptoms and can cause damage to the body over time.
  • If you experience any side effects or have concerns about the medication, talk to your doctor or pharmacist. They may be able to adjust your dose or recommend a different medication.

Quick Tips for NEXOVAS T TABLET 10'SArrow

  • NEXOVAS T TABLET 10'S is a prescription medication used to treat high blood pressure.
  • Take the medication at the same time each day to ensure consistent blood levels.
  • Swallow the tablet whole with a glass of water; do not crush or chew it.
  • It may take several weeks of regular use to see the full benefit of the medication.
  • Do not stop taking the medication without first consulting with your doctor.
  • Inform your doctor of any other medications you are taking, including over-the-counter and herbal products.
  • Avoid drinking alcohol while taking this medication.
  • This medication may cause dizziness or fainting; avoid driving or operating heavy machinery until you know how it affects you.
  • If you miss a dose, take it as soon as you remember. Do not take a double dose to make up for a missed one.
  • If you have any concerns about the medication, talk to your doctor or pharmacist.

Food Interactions with NEXOVAS T TABLET 10'SArrow

  • NEXOVAS T TABLET 10'S is a medication used to treat high blood pressure, and a healthy diet can help support its effectiveness.
  • A diet low in salt (sodium) is recommended while taking this medication as it can help lower blood pressure.
  • Avoid processed and packaged foods that are high in salt, such as chips, canned foods, and processed meats.
  • Choose fresh fruits and vegetables, lean protein sources, and whole grains to maintain a healthy diet.
  • Foods high in potassium, such as bananas, spinach, and sweet potatoes, may help counteract the effects of high sodium levels and benefit blood pressure control.
  • Consult with a registered dietitian or healthcare provider to develop a personalized meal plan that meets your nutritional needs and complements your medication therapy.
  • Avoid drinking grapefruit juice while taking NEXOVAS T TABLET 10'S as it can interfere with the medication's effectiveness.
  • Alcohol consumption should be limited or avoided altogether while taking this medication as it can lead to increased blood pressure levels and potentially reduce the medication's effectiveness.

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FAQs

What is NEXOVAS T TABLET 10'S used for?Arrow

NEXOVAS T TABLET 10'S is used to treat high blood pressure.

How does NEXOVAS T TABLET 10'S work?Arrow

NEXOVAS T TABLET 10'S works by relaxing the blood vessels, making it easier for the heart to pump blood and reducing the workload on the heart.

How should I take NEXOVAS T TABLET 10'S ?Arrow

NEXOVAS T TABLET 10'S should be taken as directed by your doctor. It is usually taken once a day, with or without food, at the same time each day.

What should I do if I miss a dose of NEXOVAS T TABLET 10'S ?Arrow

If you miss a dose of NEXOVAS T TABLET 10'S , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Can I drink alcohol while taking NEXOVAS T TABLET 10'S ?Arrow

It is recommended to avoid or limit alcohol consumption while taking NEXOVAS T TABLET 10'S as alcohol can increase blood pressure levels and potentially reduce the medication's effectiveness.

What should I do if I experience side effects while taking NEXOVAS T TABLET 10'S ?Arrow

If you experience any side effects while taking NEXOVAS T TABLET 10'S , contact your doctor or healthcare provider immediately. They can provide guidance on the best course of action, which may include adjusting your dosage or switching to a different medication.

Is NEXOVAS T TABLET 10'S safe for use during pregnancy or while breastfeeding?Arrow

NEXOVAS T TABLET 10'S should only be used during pregnancy or while breastfeeding if recommended by your doctor. Speak to your healthcare provider about the potential risks and benefits of the medication in your specific situation.

Can NEXOVAS T TABLET 10'S be taken with other medications?Arrow

NEXOVAS T TABLET 10'S can interact with other medications, including over-the-counter and herbal products. Always inform your doctor or healthcare provider of any other medications you are taking before starting NEXOVAS T TABLET 10'S .

What is Nexovas T used for?Arrow

Nexovas T is primarily used for the treatment of high blood pressure (essential hypertension) in adults. It is a fixed-dose combination of cilnidipine, a calcium channel blocker, and telmisartan, an angiotensin II receptor blocker. Together, these medicines relax and widen blood vessels, reduce peripheral vascular resistance, and help lower blood pressure. By maintaining blood pressure within the target range, Nexovas T helps reduce the long-term risk of complications such as stroke, heart attack, heart failure, and kidney damage when used as part of an overall cardiovascular risk management plan.

How does Nexovas T work in the body?Arrow

Nexovas T works through two complementary mechanisms. Cilnidipine blocks L-type and N-type calcium channels in vascular smooth muscle and sympathetic nerve endings, leading to relaxation of blood vessels and reduced sympathetic outflow, which lowers blood pressure. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictor and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium and water retention, and decreased blood pressure. The combination provides more effective and sustained blood pressure control than either component alone in many patients.

How should Nexovas T be taken?Arrow

Nexovas T should be taken exactly as prescribed by a registered medical practitioner. It is usually taken once daily at the same time each day, with or without food. The tablet should be swallowed whole with a glass of water and should not be crushed, broken, or chewed unless your doctor or pharmacist specifically advises otherwise. Do not change the dose, frequency, or duration of use on your own. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; in that case, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

What are the common side effects of Nexovas T?Arrow

Common side effects associated with Nexovas T may include dizziness, light-headedness (especially when standing up quickly), headache, flushing, ankle or leg swelling, fatigue, palpitations, and mild gastrointestinal symptoms such as nausea, abdominal discomfort, or constipation. Some patients may experience a feeling of weakness or increased urination at the start of therapy. These effects are often mild and may improve as the body adjusts to the medicine. If side effects are persistent, bothersome, or worsening, you should consult your doctor. Sudden severe dizziness, fainting, chest pain, difficulty breathing, or swelling of the face, lips, or tongue require urgent medical attention.

Can Nexovas T be used during pregnancy?Arrow

Nexovas T is generally contraindicated during pregnancy, especially in the second and third trimesters. Telmisartan, an angiotensin II receptor blocker, can cause serious harm to the developing fetus, including kidney dysfunction, reduced amniotic fluid, skull abnormalities, and even fetal death. If you are planning a pregnancy, your doctor will usually switch you to an alternative antihypertensive with a better-established safety profile in pregnancy. If you become pregnant while taking Nexovas T, you should inform your doctor immediately so that the medicine can be discontinued and replaced with a safer alternative as soon as possible.

Is Nexovas T safe while breastfeeding?Arrow

The safety of Nexovas T during breastfeeding is not well established. Telmisartan may pass into breast milk to an unknown extent, and potential effects on the nursing infant cannot be ruled out. Cilnidipine data in lactation are also limited. Therefore, Nexovas T is generally not recommended during breastfeeding unless the potential benefit to the mother clearly outweighs any possible risk to the infant and no suitable alternative is available. Your doctor may advise switching to an antihypertensive with more established safety data in breastfeeding or may recommend avoiding breastfeeding while on this combination.

Can I drink alcohol while taking Nexovas T?Arrow

Alcohol can enhance the blood pressure-lowering effect of Nexovas T and may increase the risk of dizziness, light-headedness, or fainting, particularly when standing up quickly. Excessive alcohol intake can also worsen blood pressure control and counteract the benefits of treatment. It is advisable to limit or avoid alcohol while taking Nexovas T. If you choose to drink, do so in moderation and be alert to symptoms such as dizziness or weakness. Discuss your alcohol consumption with your doctor so that your overall cardiovascular risk and treatment plan can be appropriately managed.

What precautions should patients with kidney problems take with Nexovas T?Arrow

Patients with pre-existing kidney disease should use Nexovas T with caution and under close medical supervision. Telmisartan can affect kidney function, particularly in individuals with renal artery stenosis, severe heart failure, dehydration, or those taking other medicines that influence kidney function, such as NSAIDs or certain diuretics. Your doctor may order baseline and periodic tests of kidney function (serum creatinine, estimated glomerular filtration rate) and electrolytes, especially potassium. If there is a significant decline in kidney function or a marked rise in potassium levels, your doctor may adjust the dose, modify other medicines, or discontinue Nexovas T.

Can Nexovas T cause high potassium levels?Arrow

Yes, Nexovas T can increase serum potassium levels (hyperkalaemia), mainly due to the telmisartan component, which reduces aldosterone-mediated potassium excretion in the kidneys. The risk is higher in patients with kidney impairment, diabetes, older age, or those taking other medicines that raise potassium, such as potassium-sparing diuretics, potassium supplements, or certain other antihypertensives. Symptoms of significant hyperkalaemia may include muscle weakness, palpitations, or abnormal heart rhythms, but it can also be asymptomatic. Regular monitoring of serum potassium is recommended in at-risk patients, and you should not take potassium supplements or salt substitutes containing potassium without medical advice.

What should I do if I feel very dizzy or faint after taking Nexovas T?Arrow

If you feel very dizzy, light-headed, or close to fainting after taking Nexovas T, sit or lie down immediately to reduce the risk of falling and injury. Rise slowly from sitting or lying positions. Such symptoms may indicate an excessive drop in blood pressure, especially at the start of treatment, after a dose change, or if you are dehydrated. If the dizziness is severe, persistent, or associated with chest pain, shortness of breath, confusion, or loss of consciousness, seek urgent medical attention. Inform your doctor about these symptoms; your dose, timing, or concomitant medicines may need adjustment, or additional evaluation may be required.

Can I stop taking Nexovas T once my blood pressure is controlled?Arrow

You should not stop taking Nexovas T on your own, even if your blood pressure readings have improved and you feel well. Hypertension is often a chronic condition, and stopping treatment abruptly can lead to a rebound increase in blood pressure and a higher risk of cardiovascular events. Any decision to reduce the dose or discontinue Nexovas T should be made by your doctor based on a comprehensive assessment, including blood pressure trends, overall cardiovascular risk, and lifestyle measures. If a change is appropriate, your doctor will guide you on how to adjust therapy safely.

References

Book Icon

PubChem. (2023). Cilnidipine. Retrieved May 1, 2023, from @pubchem website: https://pubchem.ncbi.nlm.nih.gov/compound/cilnidipine

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MACLEODS PHARMACEUTICALS PRIVATE LIMITED

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India

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