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NICARDIA RETARD 10MG TABLET 15'S

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NICARDIA RETARD 10MG TABLET 15'S

By J B CHEMICALS AND PHARMACEUTICALS LTD

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52.95

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About NICARDIA RETARD 10MG TABLET 15'S

  • Nicardia Retard 10 is a branded sustained‑release formulation of nifedipine, a calcium channel blocker belonging to the dihydropyridine class. It is primarily used for the management of high blood pressure (hypertension) and certain types of angina (chest pain due to reduced blood flow to the heart). By blocking L‑type calcium channels in vascular smooth muscle, nifedipine causes relaxation and widening of peripheral and coronary arteries. This vasodilation lowers systemic vascular resistance and improves coronary blood flow, which helps reduce blood pressure and relieve anginal symptoms. The “retard” or sustained‑release form is designed to release nifedipine gradually over an extended period, helping to maintain more stable blood levels and smoother blood pressure control compared with immediate‑release preparations. This can reduce fluctuations in blood pressure and may lower the risk of sudden drops that can cause dizziness or fainting. Nicardia Retard 10 is generally used as part of long‑term therapy and is often combined with lifestyle measures such as salt restriction, weight management, regular physical activity, and smoking cessation. Clinically, Nicardia Retard 10 is indicated in essential (primary) hypertension and may be used alone or with other antihypertensive agents such as ACE inhibitors, angiotensin receptor blockers, diuretics, or beta‑blockers, depending on individual patient needs. It is also used in chronic stable angina and sometimes in vasospastic (Prinzmetal’s) angina, where it helps prevent coronary artery spasm. In some settings, nifedipine may be used off‑label for conditions involving arterial spasm, such as Raynaud’s phenomenon, but such use should only be under specialist supervision. Common adverse effects include headache, flushing, dizziness, palpitations, ankle or foot swelling (peripheral edema), and fatigue, which are usually related to vasodilation. Gingival overgrowth can occur with prolonged use. More serious but less common reactions include significant hypotension, worsening angina, or, rarely, myocardial infarction in susceptible patients, especially if blood pressure falls too rapidly. Nicardia Retard 10 should not be used for the emergency treatment of hypertensive crises or acute anginal attacks, as its onset of action is not rapid enough for acute management. The medicine must be taken exactly as prescribed by a registered medical practitioner. Tablets should generally be swallowed whole with water and not crushed, broken, or chewed, to preserve the sustained‑release properties. Abrupt discontinuation without medical advice is discouraged because it may lead to rebound increases in blood pressure or exacerbation of angina. Dose selection, titration, and treatment duration depend on the patient’s clinical condition, comorbidities, concomitant medications, and response to therapy. Regular monitoring of blood pressure, heart rate, and clinical symptoms is important to ensure safe and effective use. Patients should always consult their doctor or pharmacist for individualized advice before starting, stopping, or changing Nicardia Retard 10.

Uses of NICARDIA RETARD 10MG TABLET 15'S

  • Hypertension: This medication helps manage high blood pressure, reducing strain on the heart and lowering the risk of complications like stroke and kidney problems.
  • Angina: NICARDIA RETARD 10MG TABLET 15'S helps alleviate chest pain caused by angina by improving blood flow to the heart and providing necessary oxygen to the heart muscle.

How NICARDIA RETARD 10MG TABLET 15'S Works

  • NICARDIA RETARD 10MG TABLET 15'S works by blocking calcium channels in blood vessels, which relaxes and widens them, resulting in improved blood flow and reduced blood pressure.
  • NICARDIA RETARD 10MG TABLET 15'S exerts its effects by blocking the influx of calcium ions through specific channels in the smooth muscle cells of blood vessels. By doing so, it reduces the contractility of the arterial walls, leading to relaxation and dilation of the blood vessels. This action helps to lower blood pressure and improve blood flow to the heart, reducing the workload on the organ. Additionally, the relaxation of smooth muscle in the coronary arteries enhances blood supply to the heart muscle, alleviating chest pain (angina). Furthermore, NICARDIA RETARD 10MG TABLET 15'S inhibits calcium ion influx in the myometrium (muscle layer of the uterus), which helps prevent preterm contractions. Overall, these mechanisms contribute to the therapeutic benefits of NICARDIA RETARD 10MG TABLET 15'S in hypertension, angina, and preterm labor prevention.

Side Effects of NICARDIA RETARD 10MG TABLET 15'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Headache
  • Peripheral edema
  • Dizziness
  • Fatigue
  • Constipation
  • Swelling, particularly of the ankles and legs

Safety Advice for NICARDIA RETARD 10MG TABLET 15'SArrow

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Heart and circulation

Use under cardiology guidance in high‑risk patients

Nicardia Retard 10 can cause vasodilation and reflex increases in heart rate, which may not be suitable for some patients with severe aortic stenosis, unstable angina, or recent myocardial infarction unless managed by a specialist.

Dosage of NICARDIA RETARD 10MG TABLET 15'SArrow

  • Always adhere to your doctor's instructions regarding the use of NICARDIA RETARD 10MG TABLET 15'S. It is crucial to follow their advice for optimal results and to minimize potential risks. This medication is designed for oral administration, and it's important to swallow it whole. Avoid crushing, chewing, or breaking the tablet, as this could affect how the medication is released and absorbed into your system.
  • Your healthcare provider will determine the appropriate dosage and treatment duration based on several factors, including your age, body weight, overall health condition, and the specific nature of your ailment. It is essential to attend all scheduled follow-up appointments so that your doctor can monitor your progress and make any necessary adjustments to your treatment plan.
  • Consistency is key when taking NICARDIA RETARD 10MG TABLET 15'S. Try to take the medication at the same time each day to maintain a steady level of the drug in your bloodstream. If you have any questions or concerns about your dosage or treatment schedule, do not hesitate to reach out to your doctor or pharmacist for clarification.
  • It is very important to only discontinue the usage of this tablet if your doctor advises you to stop. Suddenly stopping the medication can lead to unwanted side effects.

How to store NICARDIA RETARD 10MG TABLET 15'S?Arrow

  • Keep NICARDIA RETARD 10MG TAB 1X15 away from the reach of children and pets.
  • Store NICARDIA RETARD 10MG TAB 1X15 at room temperature.

Benefits of NICARDIA RETARD 10MG TABLET 15'SArrow

  • NICARDIA RETARD 10MG TABLET 15'S is a medication that primarily functions by interfering with the movement of calcium ions into specific cells within the body. This includes muscle cells found in both blood vessels and the heart.
  • The action of blocking calcium ions is crucial because it directly impacts the contraction of smooth muscle cells present in blood vessels. By inhibiting the influx of calcium, the tablet promotes vasodilation, effectively widening the blood vessels.
  • This widening of blood vessels has a significant consequence: it leads to a reduction in blood pressure. This mechanism makes NICARDIA RETARD 10MG TABLET 15'S valuable in managing conditions related to high blood pressure, as it helps to alleviate the strain on the cardiovascular system.
  • Furthermore, by controlling calcium influx, the medication also plays a role in managing certain heart conditions where reducing the workload on the heart is beneficial. The targeted action on calcium channels contributes to its therapeutic effects.
  • The precise and controlled release of the medication ensures a sustained effect, providing a more consistent therapeutic benefit over an extended period. This controlled release mechanism is designed to optimize the drug's efficacy and minimize potential fluctuations in blood pressure levels.

How to use NICARDIA RETARD 10MG TABLET 15'SArrow

  • Always take NICARDIA RETARD 10MG TABLET 15'S exactly as your doctor has instructed. It is crucial to adhere to their prescribed dosage and schedule for optimal results. This medication is intended for oral administration. Swallow the tablet whole with a glass of water. Avoid altering the tablet's form by crushing, chewing, or breaking it, as this can affect how the medicine is absorbed and works in your body.
  • The appropriate dosage and duration of treatment will be determined by your doctor, considering factors such as your age, body weight, overall health condition, and the severity of your specific ailment. It is imperative not to deviate from the prescribed dosage or treatment duration without consulting your doctor. Self-adjusting the dosage can lead to adverse effects or a lack of therapeutic benefit.
  • Consistency is key when taking NICARDIA RETARD 10MG TABLET 15'S. Try to take it at the same time each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Do not discontinue taking NICARDIA RETARD 10MG TABLET 15'S without first consulting your doctor, even if you feel better. Abruptly stopping the medication can lead to a worsening of your condition or withdrawal symptoms. Your doctor will gradually reduce the dosage if it is necessary to discontinue treatment.

FAQs

What are the possible side effects of NICARDIA RETARD 10MG TABLET 15'S that I should be aware of?Arrow

Yes, side effects of NICARDIA RETARD 10MG TABLET 15'S may include severe allergic reactions and liver or kidney problems. You must seek medical attention if you encounter any side effects, such as swelling, difficulty breathing, nausea, and rashes.

Does NICARDIA RETARD 10MG TABLET 15'S cause edema?Arrow

The vasodilation of NICARDIA RETARD 10MG TABLET 15'S can lead to an increased chance of fluid leakage from the blood vessels into the surrounding tissues, resulting in edema. It occurs in the lower extremities, such as the ankles and feet. It's important to monitor for signs of edema while taking this drug and inform your healthcare provider if you notice any unusual swelling or changes in your extremities.

How long does it take time for NICARDIA RETARD 10MG TABLET 15'S to work?Arrow

Immediate-release tablets of NICARDIA RETARD 10MG TABLET 15'S typically start working within 30 minutes to 1 hour after administration. Extended-release formulations may take longer to reach their maximum effect, with onset times ranging from 1 to 2 hours.

Can NICARDIA RETARD 10MG TABLET 15'S be given sublingually?Arrow

No, NICARDIA RETARD 10MG TABLET 15'S should not be given sublingually (under the tongue). It is available in various formulations, including immediate-release tablets and extended-release capsules, which are meant to be swallowed whole with water.

How does NICARDIA RETARD 10MG TABLET 15'S work in treating low blood pressure?Arrow

NICARDIA RETARD 10MG TABLET 15'S works by blocking the influx of calcium ions into certain cells, leading to relaxation and dilation of blood vessels, which mainly helps to lower blood pressure and improve blood flow.

Can I take NICARDIA RETARD 10MG TABLET 15'S with low BP?Arrow

If you have low blood pressure (hypotension), taking NICARDIA RETARD 10MG TABLET 15'S may further decrease your blood pressure and cause symptoms such as dizziness, lightheadedness, fainting, or fatigue. Therefore, taking this drug if you have low blood pressure is generally not recommended unless specifically prescribed and closely monitored by your healthcare provider.

NULL interaction of NICARDIA RETARD 10MG TABLET 15'S with other drungsArrow

NULL interaction of NICARDIA RETARD 10MG TABLET 15'S with other drungs

Advice related to NICARDIA RETARD 10MG TABLET 15'SArrow

If you take NICARDIA RETARD 10MG TABLET 15'S regularly, try to take it simultaneously daily. It can help maintain steady levels of the medication in your body. Grapefruit juice can interact with this medicine and increase the medication's levels in your body. It's advisable to avoid consuming grapefruit or its juice while taking this drug. This medicine is prescribed specifically for your condition, and it is highly advised not to share it with others, even if they have related symptoms. Talk to your physician if you develop any symptoms that worsen, or it does not improve after taking this drug. They may need to reassess your condition and adjust your treatment if necessary.

What molecule/combination is used for making NICARDIA RETARD 10MG TABLET 15'S?Arrow

NIFEDIPINE is the molecule/combination used for making NICARDIA RETARD 10MG TABLET 15'S.

For what ailments/diseases/conditions NICARDIA RETARD 10MG TABLET 15'S is prescribed?Arrow

NICARDIA RETARD 10MG TABLET 15'S is prescribed for Cardiology.

How does NICARDIA RETARD 10MG TABLET 15'S helps with Cardiology?Arrow

NICARDIA RETARD 10MG TABLET 15'S helps reduce symptoms of Cardiology by relaxing the heart muscles and widening blood vessels.

What is Nicardia Retard 10 used for?Arrow

Nicardia Retard 10 contains nifedipine in a sustained‑release form and is mainly used to treat high blood pressure (hypertension) and chronic stable angina or vasospastic angina. By relaxing and widening blood vessels, it lowers blood pressure and improves blood flow to the heart muscle, helping to prevent chest pain episodes. It may also be used, under specialist supervision, in certain conditions associated with arterial spasm, but such uses are individualized and off‑label.

How does Nicardia Retard 10 work in the body?Arrow

Nicardia Retard 10 works by blocking L‑type calcium channels in the smooth muscle of blood vessel walls. This reduces the entry of calcium ions into cells, leading to relaxation and dilation of peripheral and coronary arteries. The fall in vascular resistance lowers blood pressure, while improved coronary blood flow helps prevent or reduce angina. The sustained‑release formulation provides a gradual, prolonged effect, helping to maintain more stable blood levels over the dosing interval.

Can Nicardia Retard 10 be used for emergency high blood pressure or acute chest pain?Arrow

No. Nicardia Retard 10 is not suitable for emergency treatment of hypertensive crises or acute anginal attacks because it is a sustained‑release preparation with a slower onset of action. For sudden, severe chest pain or very high blood pressure with symptoms such as breathlessness, severe headache, or neurological changes, urgent medical evaluation is required. Emergency management may involve different medicines and routes of administration as decided by a physician.

What are the common side effects of Nicardia Retard 10?Arrow

Common side effects include headache, flushing, dizziness or light‑headedness, palpitations, ankle or foot swelling (peripheral edema), fatigue, and a feeling of warmth. Some people may experience nausea, mild gastrointestinal discomfort, or gingival overgrowth with long‑term use. These effects are often related to vasodilation and may lessen as the body adjusts. If side effects are severe, persistent, or worrying, medical advice should be sought promptly.

Is Nicardia Retard 10 safe for long‑term use?Arrow

Nifedipine sustained‑release formulations such as Nicardia Retard 10 are commonly used for long‑term management of hypertension and angina when prescribed and monitored by a doctor. Long‑term safety is generally acceptable, but regular follow‑up is important to monitor blood pressure, heart rate, symptom control, and potential adverse effects such as peripheral edema or gum changes. Dose adjustments or changes in therapy may be needed over time based on clinical response and tolerability.

Can I stop taking Nicardia Retard 10 once my blood pressure is controlled?Arrow

You should not stop Nicardia Retard 10 on your own, even if your blood pressure readings improve. Hypertension and angina are usually chronic conditions, and stopping treatment abruptly can lead to rebound increases in blood pressure or worsening chest pain. Any change, including dose reduction or discontinuation, should be done only under medical supervision, with appropriate monitoring and, if needed, substitution with alternative therapy.

Does Nicardia Retard 10 interact with other medicines?Arrow

Yes. Nicardia Retard 10 can interact with several medicines. Strong inhibitors or inducers of the CYP3A4 enzyme (such as certain antifungals, macrolide antibiotics, some antiepileptics, and rifampicin) can alter nifedipine blood levels. Concomitant use with other blood pressure‑lowering drugs may enhance hypotensive effects. Interactions with certain beta‑blockers, digoxin, and some immunosuppressants are also possible. It is important to inform your doctor about all prescription medicines, over‑the‑counter products, and herbal supplements you are taking.

Can Nicardia Retard 10 cause swelling of the legs or ankles?Arrow

Yes. Peripheral edema, typically presenting as swelling of the ankles or feet, is a well‑recognized side effect of nifedipine and other dihydropyridine calcium channel blockers. It results from dilation of arterioles without a corresponding dilation of venous vessels, leading to increased capillary pressure and fluid leakage into tissues. While often benign, it can be uncomfortable. If swelling is marked, associated with shortness of breath, or rapidly worsening, medical evaluation is necessary to rule out heart failure or other causes and to consider treatment modification.

Is Nicardia Retard 10 suitable for all patients with high blood pressure?Arrow

Nicardia Retard 10 is not suitable for everyone. It may be inappropriate in patients with severe aortic stenosis, cardiogenic shock, unstable angina, recent myocardial infarction without specialist oversight, or severe hypotension. Caution is required in patients with significant liver impairment, heart failure, or those on interacting medicines. The decision to use Nicardia Retard 10 depends on an individual assessment of risks, benefits, comorbidities, and other ongoing treatments by a qualified physician.

How should Nicardia Retard 10 be taken for best effect?Arrow

Nicardia Retard 10 should be taken exactly as prescribed by your doctor, usually at the same time each day to maintain consistent blood levels. The tablet should be swallowed whole with water and not crushed, broken, or chewed, as this would disrupt the sustained‑release mechanism and may increase the risk of side effects. It can generally be taken with or without food, but taking it in a consistent manner relative to meals is advisable. If you miss a dose, follow your doctor’s instructions or the patient information leaflet; do not double the next dose without medical advice.

References

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Morningside Healthcare Ltd, Electronic medicines compendium (EMC).

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Package leaflet: Information for the user - Nifedipine. www.hpra.ie.

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