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Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Heart and circulation
Use under cardiology guidance in high‑risk patientsNicardia Retard 10 can cause vasodilation and reflex increases in heart rate, which may not be suitable for some patients with severe aortic stenosis, unstable angina, or recent myocardial infarction unless managed by a specialist.
Yes, side effects of NICARDIA RETARD 10MG TABLET 15'S may include severe allergic reactions and liver or kidney problems. You must seek medical attention if you encounter any side effects, such as swelling, difficulty breathing, nausea, and rashes.
The vasodilation of NICARDIA RETARD 10MG TABLET 15'S can lead to an increased chance of fluid leakage from the blood vessels into the surrounding tissues, resulting in edema. It occurs in the lower extremities, such as the ankles and feet. It's important to monitor for signs of edema while taking this drug and inform your healthcare provider if you notice any unusual swelling or changes in your extremities.
Immediate-release tablets of NICARDIA RETARD 10MG TABLET 15'S typically start working within 30 minutes to 1 hour after administration. Extended-release formulations may take longer to reach their maximum effect, with onset times ranging from 1 to 2 hours.
No, NICARDIA RETARD 10MG TABLET 15'S should not be given sublingually (under the tongue). It is available in various formulations, including immediate-release tablets and extended-release capsules, which are meant to be swallowed whole with water.
NICARDIA RETARD 10MG TABLET 15'S works by blocking the influx of calcium ions into certain cells, leading to relaxation and dilation of blood vessels, which mainly helps to lower blood pressure and improve blood flow.
If you have low blood pressure (hypotension), taking NICARDIA RETARD 10MG TABLET 15'S may further decrease your blood pressure and cause symptoms such as dizziness, lightheadedness, fainting, or fatigue. Therefore, taking this drug if you have low blood pressure is generally not recommended unless specifically prescribed and closely monitored by your healthcare provider.
NULL interaction of NICARDIA RETARD 10MG TABLET 15'S with other drungs
If you take NICARDIA RETARD 10MG TABLET 15'S regularly, try to take it simultaneously daily. It can help maintain steady levels of the medication in your body. Grapefruit juice can interact with this medicine and increase the medication's levels in your body. It's advisable to avoid consuming grapefruit or its juice while taking this drug. This medicine is prescribed specifically for your condition, and it is highly advised not to share it with others, even if they have related symptoms. Talk to your physician if you develop any symptoms that worsen, or it does not improve after taking this drug. They may need to reassess your condition and adjust your treatment if necessary.
NIFEDIPINE is the molecule/combination used for making NICARDIA RETARD 10MG TABLET 15'S.
NICARDIA RETARD 10MG TABLET 15'S is prescribed for Cardiology.
NICARDIA RETARD 10MG TABLET 15'S helps reduce symptoms of Cardiology by relaxing the heart muscles and widening blood vessels.
Nicardia Retard 10 contains nifedipine in a sustained‑release form and is mainly used to treat high blood pressure (hypertension) and chronic stable angina or vasospastic angina. By relaxing and widening blood vessels, it lowers blood pressure and improves blood flow to the heart muscle, helping to prevent chest pain episodes. It may also be used, under specialist supervision, in certain conditions associated with arterial spasm, but such uses are individualized and off‑label.
Nicardia Retard 10 works by blocking L‑type calcium channels in the smooth muscle of blood vessel walls. This reduces the entry of calcium ions into cells, leading to relaxation and dilation of peripheral and coronary arteries. The fall in vascular resistance lowers blood pressure, while improved coronary blood flow helps prevent or reduce angina. The sustained‑release formulation provides a gradual, prolonged effect, helping to maintain more stable blood levels over the dosing interval.
No. Nicardia Retard 10 is not suitable for emergency treatment of hypertensive crises or acute anginal attacks because it is a sustained‑release preparation with a slower onset of action. For sudden, severe chest pain or very high blood pressure with symptoms such as breathlessness, severe headache, or neurological changes, urgent medical evaluation is required. Emergency management may involve different medicines and routes of administration as decided by a physician.
Common side effects include headache, flushing, dizziness or light‑headedness, palpitations, ankle or foot swelling (peripheral edema), fatigue, and a feeling of warmth. Some people may experience nausea, mild gastrointestinal discomfort, or gingival overgrowth with long‑term use. These effects are often related to vasodilation and may lessen as the body adjusts. If side effects are severe, persistent, or worrying, medical advice should be sought promptly.
Nifedipine sustained‑release formulations such as Nicardia Retard 10 are commonly used for long‑term management of hypertension and angina when prescribed and monitored by a doctor. Long‑term safety is generally acceptable, but regular follow‑up is important to monitor blood pressure, heart rate, symptom control, and potential adverse effects such as peripheral edema or gum changes. Dose adjustments or changes in therapy may be needed over time based on clinical response and tolerability.
You should not stop Nicardia Retard 10 on your own, even if your blood pressure readings improve. Hypertension and angina are usually chronic conditions, and stopping treatment abruptly can lead to rebound increases in blood pressure or worsening chest pain. Any change, including dose reduction or discontinuation, should be done only under medical supervision, with appropriate monitoring and, if needed, substitution with alternative therapy.
Yes. Nicardia Retard 10 can interact with several medicines. Strong inhibitors or inducers of the CYP3A4 enzyme (such as certain antifungals, macrolide antibiotics, some antiepileptics, and rifampicin) can alter nifedipine blood levels. Concomitant use with other blood pressure‑lowering drugs may enhance hypotensive effects. Interactions with certain beta‑blockers, digoxin, and some immunosuppressants are also possible. It is important to inform your doctor about all prescription medicines, over‑the‑counter products, and herbal supplements you are taking.
Yes. Peripheral edema, typically presenting as swelling of the ankles or feet, is a well‑recognized side effect of nifedipine and other dihydropyridine calcium channel blockers. It results from dilation of arterioles without a corresponding dilation of venous vessels, leading to increased capillary pressure and fluid leakage into tissues. While often benign, it can be uncomfortable. If swelling is marked, associated with shortness of breath, or rapidly worsening, medical evaluation is necessary to rule out heart failure or other causes and to consider treatment modification.
Nicardia Retard 10 is not suitable for everyone. It may be inappropriate in patients with severe aortic stenosis, cardiogenic shock, unstable angina, recent myocardial infarction without specialist oversight, or severe hypotension. Caution is required in patients with significant liver impairment, heart failure, or those on interacting medicines. The decision to use Nicardia Retard 10 depends on an individual assessment of risks, benefits, comorbidities, and other ongoing treatments by a qualified physician.
Nicardia Retard 10 should be taken exactly as prescribed by your doctor, usually at the same time each day to maintain consistent blood levels. The tablet should be swallowed whole with water and not crushed, broken, or chewed, as this would disrupt the sustained‑release mechanism and may increase the risk of side effects. It can generally be taken with or without food, but taking it in a consistent manner relative to meals is advisable. If you miss a dose, follow your doctor’s instructions or the patient information leaflet; do not double the next dose without medical advice.
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J B CHEMICALS AND PHARMACEUTICALS LTD
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India
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