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Composition
Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Common side effects of Olapad Plus Tablet may include: * Sleepiness * Dryness in mouth * Headache. Less common side effects: * Dizziness * Nausea * Vomiting * Diarrhea * Fatigue * Blurred vision * Difficulty in concentrating * Restlessness * Increased sweating * Muscle pain * Skin rash or itching * Urinary retention * Confusion (especially in elderly patients) * Low blood pressure (hypotension)

Other Medical Conditions and Interactions
Inform your doctorPatients with a history of seizures, diabetes, cardiovascular disease, glaucoma, low white blood cell counts, or a history of mania or hypomania should use Olapad Plus only under close medical supervision.
Olapad Plus Tablet 10'S is a combination medicine used to relieve symptoms of allergy such as runny nose, stuffy nose, sneezing, watery eyes, and itching.
Olapad Plus Tablet 10'S contains Olopatadine and Phenylephrine as active ingredients.
Take Olapad Plus Tablet 10'S in the dose and duration as advised by the doctor. Swallow it as a whole. Do not chew, crush or break it.
Common side effects of Olapad Plus Tablet 10'S include nausea, vomiting, headache, dry mouth, and fatigue.
Olapad Plus Tablet 10'S can be taken with or without food, but it is better to take it at a fixed time every day.
Store Olapad Plus Tablet 10'S at room temperature, away from heat and direct light. Keep it out of reach of children and pets.
There is not enough information available on the safety of Olapad Plus Tablet 10'S during pregnancy. Therefore, consult a doctor before taking it if you are pregnant or planning to become pregnant.
There is not enough information available on the safety of Olapad Plus Tablet 10'S during breastfeeding. Therefore, consult a doctor before taking it if you are breastfeeding.
Drinking alcohol while taking Olapad Plus Tablet 10'S can increase side effects such as dizziness and drowsiness. Therefore, avoid drinking alcohol while taking it.
Yes, Olapad Plus Tablet 10'S can cause drowsiness. Therefore, avoid driving or operating machinery if you feel drowsy after taking this medicine.
If you miss a dose of Olapad Plus Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
It is important to consult a doctor before giving Olapad Plus Tablet 10'S to children, as the dosage varies for children.
Yes, an overdose of Olapad Plus Tablet 10'S can be dangerous and can cause serious side effects. Therefore, always follow the dosage prescribed by your doctor.
Alternatives to Olapad Plus Tablet 10'S may vary based on your symptoms and medical history. Consult your doctor for advice on other suitable options.
No, Olapad Plus Tablet 10'S is not an habit-forming medicine.
Olapad Plus is a combination of fluoxetine (an SSRI antidepressant) and olanzapine (an atypical antipsychotic). It is generally used in adults for depressive episodes associated with bipolar disorder and for treatment‑resistant major depressive disorder when adequate response has not been achieved with antidepressant therapy alone. The exact indication for an individual patient should be determined by a psychiatrist or qualified physician.
Fluoxetine in Olapad Plus increases serotonin levels in the brain by inhibiting its reuptake, which helps improve mood and reduce depressive symptoms. Olanzapine acts on several neurotransmitter receptors, including dopamine and serotonin receptors, helping to stabilize mood, reduce psychotic symptoms if present, and improve sleep and appetite. The combined effect targets multiple pathways involved in mood regulation and treatment‑resistant depression.
Some patients may notice partial improvement in sleep, appetite, or anxiety within 1 to 2 weeks, but full antidepressant and mood‑stabilizing effects often require several weeks. Clinically meaningful improvement is usually assessed after 4 to 6 weeks or longer, depending on the individual and the underlying condition. Treatment duration and response should be regularly reviewed by the prescribing doctor.
You should not stop Olapad Plus on your own, even if you feel better. Abrupt discontinuation can lead to withdrawal‑like symptoms, return or worsening of depression, mood instability, or other psychiatric symptoms. Any change in dose or discontinuation should be done gradually and only under medical supervision, following a tapering plan recommended by your doctor.
Common side effects may include weight gain, increased appetite, drowsiness, dizziness, dry mouth, constipation, fatigue, and changes in sleep pattern. Some people may experience restlessness, tremor, sexual dysfunction, or gastrointestinal upset such as nausea or diarrhea. Not everyone experiences these effects, and their intensity can vary. Persistent or troublesome side effects should be discussed with your doctor.
Serious but less common risks include metabolic changes such as high blood sugar or lipid abnormalities, significant weight gain, neuroleptic malignant syndrome, serotonin syndrome, severe allergic reactions, seizures in susceptible individuals, and changes in heart rhythm. There is also a known risk of suicidal thoughts or behavior, particularly in younger patients, when starting antidepressant therapy. Any sudden change in mood, agitation, or self‑harm thoughts requires urgent medical attention.
Olapad Plus can interact with other antidepressants, antipsychotics, and medicines that affect serotonin or dopamine. Combining it with certain drugs may increase the risk of serotonin syndrome, excessive sedation, heart rhythm disturbances, or other adverse effects. You should inform your doctor about all prescription, over‑the‑counter, and herbal products you use. Only a qualified clinician should decide whether combination therapy is appropriate and safe.
Olapad Plus is not considered a classic addictive or habit‑forming medicine in the way that some sedatives or opioids are. However, stopping it suddenly can cause withdrawal‑like symptoms or relapse of the underlying psychiatric condition. Psychological dependence on the improvement in mood or functioning is possible, which is why any change in therapy should be carefully planned with your doctor.
Older adults may be more sensitive to side effects such as sedation, dizziness, orthostatic hypotension, metabolic changes, and movement disorders. There is also an increased risk of falls and, in some cases, cerebrovascular events in elderly patients with dementia‑related psychosis treated with antipsychotics. Use in older adults requires careful dose selection, close monitoring, and regular review of risks and benefits by the treating physician.
If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. If it is close to the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you frequently forget doses, discuss this with your doctor, as consistent dosing is important for stable symptom control.
Yes. Olanzapine, one of the components of Olapad Plus, is associated with weight gain and metabolic changes, including increased blood sugar and lipid levels. Patients with diabetes or those at risk of metabolic syndrome require close monitoring of weight, fasting blood glucose, and lipid profile. Lifestyle measures such as diet and physical activity should be discussed with your doctor, and medication adjustments may be needed if significant changes occur.
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TRIPADA HEALTHCARE PRIVATE LIMITED
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India

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