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ONCOTREX 5MG TABLET 10'S

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ONCOTREX 5MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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98.91

₹84.07

15 % OFF

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About ONCOTREX 5MG TABLET 10'S

  • ONCOTREX 5MG TABLET 10'S is a medication prescribed for the treatment of various cancers affecting areas such as the breasts, head, neck, lungs, blood, bone, lymph nodes, and uterus. It also serves as a treatment for rheumatoid arthritis, severe psoriasis that is not well controlled, and Crohn’s disease. This versatile medication can be administered independently or in conjunction with other drugs, depending on the specific needs of the patient and the type of cancer or condition being addressed.
  • It is crucial to adhere to your doctor's instructions regarding the dosage and administration of ONCOTREX 5MG TABLET 10'S. Exceeding the prescribed dose can lead to serious adverse effects. While the therapeutic benefits may not be immediately apparent, it is important to continue taking the medication as directed by your doctor, even if you do not experience noticeable improvements in the initial weeks or months. Discontinuing the medication without consulting your doctor is not recommended.
  • Alcohol consumption should be avoided during treatment with this medicine, as it can elevate the risk of liver damage. Common side effects associated with ONCOTREX 5MG TABLET 10'S include ulcerative stomatitis (mouth sores), hair loss, reduced blood cell count, elevated liver enzyme levels, nausea, and abdominal discomfort. To mitigate some of these side effects, your doctor may recommend taking folic acid supplements. It’s vital to promptly inform your doctor if side effects persist or worsen.
  • This medication can potentially weaken your body's ability to fight off infections and may lead to complications involving your blood, liver, or kidneys. Regular monitoring through blood tests, X-rays, and physical examinations may be conducted by your doctor both before and during treatment to detect any such issues early on. Inform your doctor about any pre-existing conditions affecting your stomach, liver, or kidneys, as well as any other medications you are currently taking, including those for treating infections. It is essential to provide your healthcare team with a comprehensive list of all medications you are using, as interactions can occur.
  • ONCOTREX 5MG TABLET 10'S is generally not recommended for use during pregnancy or breastfeeding due to the potential harm it may pose to the developing baby.

Uses of ONCOTREX 5MG TABLET 10'S

  • Treatment of Cancer, focusing on therapies and management strategies for various types of cancer to improve patient outcomes and quality of life.
  • Treatment of Rheumatoid Arthritis, emphasizing methods to alleviate pain, reduce inflammation, and slow the progression of this chronic autoimmune disease.
  • Treatment of Psoriasis, detailing various approaches to manage skin inflammation and scaling associated with this persistent skin condition.
  • Treatment of Crohn’s Disease, outlining therapeutic interventions and lifestyle adjustments to control symptoms and improve the well-being of individuals affected by this inflammatory bowel disease, using ONCOTREX 5MG TABLET 10'S.

How ONCOTREX 5MG TABLET 10'S Works

  • ONCOTREX 5MG TABLET 10'S works by inhibiting the enzyme dihydrofolate reductase. This inhibition is crucial because dihydrofolate reductase plays a key role in cell division and DNA production. By blocking this enzyme, ONCOTREX 5MG TABLET 10'S effectively prevents cells from dividing and multiplying, which is particularly useful in treating conditions characterized by rapid cell growth, such as cancer and psoriasis.
  • In the context of cancer treatment, ONCOTREX 5MG TABLET 10'S halts the production of DNA within cancer cells. Since DNA is essential for cell survival and replication, preventing its synthesis leads to the death of cancer cells. This mechanism helps to control the spread of cancerous cells and reduce the size of tumors.
  • For individuals with psoriasis, ONCOTREX 5MG TABLET 10'S helps to manage the condition by slowing down the excessive production of skin cells. Psoriasis is characterized by rapid skin cell turnover, leading to the formation of thick, scaly patches on the skin. By inhibiting cell division, ONCOTREX 5MG TABLET 10'S reduces the rate at which skin cells are produced, alleviating the symptoms of psoriasis. Additionally, it possesses anti-inflammatory properties that further contribute to the management of psoriasis.
  • In rheumatoid arthritis and Crohn's disease, ONCOTREX 5MG TABLET 10'S acts as an immunosuppressant. It suppresses the body's immune system, preventing it from mistakenly attacking its own cells. This is especially beneficial in rheumatoid arthritis, where the immune system targets the joints, causing inflammation, pain, and stiffness. By suppressing the immune response, ONCOTREX 5MG TABLET 10'S reduces inflammation and alleviates the symptoms of rheumatoid arthritis. Similarly, in Crohn's disease, it helps manage inflammation in the bowel.
  • Furthermore, the anti-inflammatory actions of ONCOTREX 5MG TABLET 10'S extend beyond its effects on the immune system. It can help reduce overall inflammation in the body, contributing to its effectiveness in treating a variety of conditions.

Side Effects of ONCOTREX 5MG TABLET 10'SArrow

Most side effects are temporary and generally disappear as your body adapts to ONCOTREX 5MG TABLET 10'S. However, if any side effects persist or cause you concern, it's important to consult your doctor.

  • Ulcerative stomatitis
  • Nausea
  • Abdominal pain
  • Increased liver enzymes
  • Hair loss
  • Decreased blood cells (red cells, white cells, and platelets)

Safety Advice for ONCOTREX 5MG TABLET 10'SArrow

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Liver Function

Caution

ONCOTREX 5MG TABLET 10'S should be used with caution in patients with liver disease. Dose adjustment of ONCOTREX 5MG TABLET 10'S may be needed. Please consult your doctor.

Dosage of ONCOTREX 5MG TABLET 10'SArrow

  • For Children: The dosage for children is based on their body surface area (BSA) or weight. Typically, the starting dose ranges from 10 to 20 mg/m² per week, divided into several smaller doses. The dosage may be adjusted based on the child's response to treatment and any potential side effects.
  • For Adults: For adults, the dosage of ONCOTREX 5MG TABLET 10'S can vary depending on the condition being treated. For certain cancers, the typical starting dose ranges from 10 to 25 mg/m² per week, divided into several smaller doses. In the case of rheumatoid arthritis, the initial dosage is often lower, usually starting with 7.5 mg per week, which may be increased gradually.

How to store ONCOTREX 5MG TABLET 10'S?Arrow

  • Keep ONCOTREX 5MG TAB 1X10 away from the reach of children and pets.
  • Store ONCOTREX 5MG TAB 1X10 at room temperature.

Benefits of ONCOTREX 5MG TABLET 10'SArrow

  • **Treatment of Cancer:** ONCOTREX 5MG TABLET 10'S works by inhibiting the growth of cancer cells. It's prescribed for various cancers, including acute leukemias, non-Hodgkin’s lymphoma, and solid tumors affecting the breast, lung, bladder, head, neck, cervix, ovaries, and testicles. It can be used alone or with other medications. This potent medication requires a thorough discussion of risks and benefits with your doctor. Avoid alcohol during treatment and stay well-hydrated by drinking plenty of water. Regular monitoring by your healthcare provider is crucial to manage potential side effects and ensure the treatment's effectiveness. Lifestyle adjustments, such as a balanced diet and moderate exercise, may also be recommended to support your overall well-being during cancer treatment.
  • **Treatment of Rheumatoid Arthritis:** ONCOTREX 5MG TABLET 10'S is an antimetabolite used for severe rheumatoid arthritis when other treatments have failed. It suppresses the immune system, reducing swelling, pain, and stiffness, and improving joint function. Use it exactly as prescribed for optimal results, and do not exceed the recommended dosage. Full effects may take several months. Consistent follow-up appointments with your rheumatologist are important to monitor your progress and adjust the treatment plan as needed. Additional therapies, such as physical therapy or occupational therapy, may be incorporated to enhance joint mobility and function.
  • **Treatment of Psoriasis:** As an antimetabolite, ONCOTREX 5MG TABLET 10'S treats severe psoriasis when other treatments are ineffective. It targets and destroys fast-growing skin cells, addressing the underlying cause of psoriasis. Discuss the risks and benefits with your doctor before starting treatment. Adhere strictly to the prescribed dosage and duration. Improvement may take several months. Avoid alcohol and maintain hydration. Regular dermatological evaluations are essential to assess the response to treatment and manage any skin-related side effects. Emollients and topical corticosteroids may be used in conjunction to alleviate symptoms like itching and scaling.
  • **Treatment of Crohn’s Disease:** Crohn’s disease, a chronic inflammatory bowel disease, causes diarrhea and abdominal pain. ONCOTREX 5MG TABLET 10'S reduces inflammation, alleviates symptoms, and prevents recurrence. Consistent medication adherence is key to managing Crohn's disease effectively. Regular check-ups with a gastroenterologist are necessary to monitor disease activity and adjust treatment as needed. Dietary modifications and stress management techniques can also play a significant role in controlling Crohn's symptoms and improving quality of life.

How to use ONCOTREX 5MG TABLET 10'SArrow

  • Always adhere to your doctor's instructions regarding the dosage and duration of ONCOTREX 5MG TABLET 10'S. This medication is designed to be swallowed whole, ensuring the integrity of its delivery system. Avoid chewing, crushing, or breaking the tablet, as this could affect how the medication is absorbed and utilized by your body. The film coating or any specific design of the tablet is there for a reason, often to control the release of the drug.
  • ONCOTREX 5MG TABLET 10'S can be taken irrespective of meals, providing you the flexibility to incorporate it into your daily routine as per your convenience. However, for optimal results and to maintain a consistent level of the medication in your system, it is advisable to take it at the same time each day. Consistency is key to the effectiveness of this medication.
  • If you happen to miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have any concerns or questions about missed doses or how to manage your medication schedule, consult your doctor or pharmacist for guidance.

Quick Tips for ONCOTREX 5MG TABLET 10'SArrow

  • Stay hydrated by drinking plenty of fluids throughout the day while you are taking ONCOTREX 5MG TABLET 10'S. Adequate hydration helps your body process the medication and can minimize potential side effects. Aim for at least eight glasses of water daily, and consider incorporating electrolyte-rich beverages if you're experiencing any fluid loss.
  • If your doctor has recommended it, take folic acid supplements regularly. Folic acid can help mitigate some of the side effects associated with ONCOTREX 5MG TABLET 10'S, particularly those affecting blood cell production. Follow your doctor's specific instructions regarding dosage and timing.
  • Understand that ONCOTREX 5MG TABLET 10'S may require several weeks or even months to produce noticeable results. It's crucial to adhere to your prescribed dosage and continue taking the medication consistently, even if you don't experience immediate improvement. Do not discontinue the medication without consulting your doctor.
  • Your doctor may schedule regular blood tests to monitor your kidney function, liver function, and blood cell counts. These tests are essential for detecting any potential adverse effects early on and ensuring the medication is being processed safely by your body. Attend all scheduled appointments and discuss any concerns you may have about the results with your doctor.
  • Avoid consuming alcohol while taking ONCOTREX 5MG TABLET 10'S, as alcohol can significantly increase the risk and severity of side effects. The combination of alcohol and this medication can put extra strain on your liver and other organs. It's best to abstain from alcohol entirely during the course of treatment.
  • ONCOTREX 5MG TABLET 10'S can be harmful to an unborn baby. It is imperative to avoid pregnancy for at least six months after your last dose of the medication. Use reliable forms of contraception during treatment and for the specified period afterward. Discuss family planning options with your doctor before starting this medication.

FAQs

Can ONCOTREX 5MG TABLET 10'S cause mouth ulcers?Arrow

Yes, ONCOTREX 5MG TABLET 10'S can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Why do I have to take folic acid with ONCOTREX 5MG TABLET 10'S?Arrow

Folic acid is required to make new cells in the body and ONCOTREX 5MG TABLET 10'S decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of ONCOTREX 5MG TABLET 10'S such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.

Why do I need to take regular blood tests while taking ONCOTREX 5MG TABLET 10'S?Arrow

Regular blood tests will help your doctor to check your response to ONCOTREX 5MG TABLET 10'S and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.

Can ONCOTREX 5MG TABLET 10'S use make me more prone to infections?Arrow

ONCOTREX 5MG TABLET 10'S may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with ONCOTREX 5MG TABLET 10'S use. If you have an active infection, ONCOTREX 5MG TABLET 10'S should be used with extreme caution.

Can ONCOTREX 5MG TABLET 10'S affect fertility?Arrow

Yes, ONCOTREX 5MG TABLET 10'S may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.

What to do if I am planning to become pregnant and my husband is taking ONCOTREX 5MG TABLET 10'S?Arrow

You should avoid pregnancy if your husband is taking ONCOTREX 5MG TABLET 10'S. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

References

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Methotrexate [Prescribing Information]. Eatontown, NJ: West-Ward Pharmaceuticals Corp.; 2020. (online) Available from:

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Methotrexate [Product Label]. New York, NY: Pfizer Inc.; 2022. (online) Available from:

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Methotrexate [Drug Label]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2022 (online) Available from:

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Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease. [Updated Sep. 2022]. (online) Available from:

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Crohn's & Colitis, UK. Methotrexate [Information Sheet]. (online) Available from:

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CiplaMed. Methotrexate [Prescribing Information]. [Last Reviewed: Feb 2019]. (online) Available from:

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ONCOTREX 5MG TABLET 10'S

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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