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ONCOTREX 7.5MG TABLET 10'S

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ONCOTREX 7.5MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

148

₹125.8

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About ONCOTREX 7.5MG TABLET 10'S

  • ONCOTREX 7.5MG TABLET 10'S is a medication prescribed for the treatment of various cancers, including those affecting the breasts, head, neck, lungs, blood, bone, lymph nodes, and uterus. It's also employed in managing rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease. This versatile medication can be administered independently or in conjunction with other drugs, depending on the specific treatment plan.
  • It is crucial to adhere strictly to your doctor's instructions regarding dosage and administration. Exceeding the prescribed dose can lead to serious side effects. While it may take several weeks or even months to experience the full benefits of ONCOTREX 7.5MG TABLET 10'S, it's essential to continue taking it as directed unless otherwise instructed by your healthcare provider. It is strongly advised to abstain from alcohol consumption during treatment with this medicine, as it can significantly elevate the risk of liver damage.
  • Common side effects associated with ONCOTREX 7.5MG TABLET 10'S include ulcerative stomatitis (mouth sores), hair loss, reduced blood cell count, elevated liver enzymes, nausea, and abdominal discomfort. Your doctor may recommend folic acid supplementation to mitigate some of these side effects. If these side effects persist or worsen, promptly inform your doctor. They may have strategies to prevent or alleviate these effects. This medication can also weaken your immune system, making you more susceptible to infections, and potentially lead to blood, liver, or kidney problems. Regular monitoring through blood tests, X-rays, and physical examinations may be conducted before and during treatment to assess these potential risks.
  • Before commencing treatment with ONCOTREX 7.5MG TABLET 10'S, inform your doctor about any pre-existing stomach, liver, or kidney conditions, as well as any medications you are currently taking, especially those for treating infections. Numerous medications can interact with ONCOTREX 7.5MG TABLET 10'S, so it's vital to provide your healthcare team with a comprehensive list of all medications you are using. This medicine is generally not recommended for use during pregnancy or breastfeeding due to the potential harm to the developing baby.

Uses of ONCOTREX 7.5MG TABLET 10'S

  • Treatment of Cancer, specifically using ONCOTREX 7.5MG TABLET 10'S in its management.
  • Treatment of Rheumatoid arthritis, potentially involving ONCOTREX 7.5MG TABLET 10'S to alleviate symptoms and improve quality of life.
  • Treatment of Psoriasis, potentially involving the use of ONCOTREX 7.5MG TABLET 10'S in the management of this condition.
  • Treatment of Crohn’s disease, including the possible use of ONCOTREX 7.5MG TABLET 10'S to manage symptoms of the disease and reduce inflammation.

How ONCOTREX 7.5MG TABLET 10'S Works

  • ONCOTREX 7.5MG TABLET 10'S works by targeting specific processes within the body to achieve its therapeutic effects. It primarily functions as an inhibitor of the enzyme dihydrofolate reductase. This enzyme is crucial for cell division, and by inhibiting it, ONCOTREX 7.5MG TABLET 10'S effectively prevents cells from dividing and multiplying. This action also contributes to its anti-inflammatory properties.
  • In the context of cancer treatment, ONCOTREX 7.5MG TABLET 10'S acts as a cytotoxic agent. It prevents cancer cells from synthesizing DNA, which is essential for their growth and proliferation. By disrupting DNA production, the medication effectively kills cancer cells, hindering the progression of the disease. This mechanism is vital in managing various types of cancers.
  • For individuals with psoriasis, ONCOTREX 7.5MG TABLET 10'S helps manage the condition by slowing down the excessive production of skin cells. Psoriasis is characterized by rapid skin cell turnover, leading to thick, scaly patches. By retarding the production of these cells and suppressing inflammation, ONCOTREX 7.5MG TABLET 10'S alleviates the symptoms of psoriasis and improves the skin's condition.
  • In rheumatoid arthritis and Crohn's disease, ONCOTREX 7.5MG TABLET 10'S exerts its effects by suppressing the immune system. In these autoimmune disorders, the immune system mistakenly attacks the body's own cells, causing inflammation and damage. By suppressing this aberrant immune response, ONCOTREX 7.5MG TABLET 10'S reduces inflammation in the joints affected by rheumatoid arthritis, alleviating swelling, stiffness, and pain. Similarly, in Crohn's disease, it helps to reduce the inflammation that damages the bowel.
  • Overall, ONCOTREX 7.5MG TABLET 10'S is a versatile medication with multiple mechanisms of action that allow it to treat a range of conditions including certain cancers, autoimmune diseases like rheumatoid arthritis, and skin disorders such as psoriasis. Its ability to inhibit cell division, suppress the immune system, and reduce inflammation makes it a valuable therapeutic agent.

Side Effects of ONCOTREX 7.5MG TABLET 10'SArrow

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

  • Ulcerative stomatitis
  • Nausea
  • Abdominal pain
  • Increased liver enzymes
  • Hair loss
  • Decreased blood cells (red cells, white cells, and platelets)

Safety Advice for ONCOTREX 7.5MG TABLET 10'SArrow

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Liver Function

Caution

ONCOTREX 7.5MG TABLET 10'S should be used with caution in patients with liver disease. Dose adjustment of ONCOTREX 7.5MG TABLET 10'S may be needed. Please consult your doctor.

Dosage of ONCOTREX 7.5MG TABLET 10'SArrow

  • For Children: The dosage for children is based on their body surface area (BSA) or weight. Typically, the starting dose ranges from 10 to 20 mg/m² per week, divided into several smaller doses. The dosage may be adjusted based on the child's response to treatment and any potential side effects.
  • For Adults: For adults, the dosage of ONCOTREX 7.5MG TABLET 10'S can vary depending on the condition being treated. For certain cancers, the typical starting dose ranges from 10 to 25 mg/m² per week, divided into several smaller doses. In the case of rheumatoid arthritis, the initial dosage is often lower, usually starting with 7.5 mg per week, which may be increased gradually.

How to store ONCOTREX 7.5MG TABLET 10'S?Arrow

  • Keep ONCOTREX 7.5MG TAB 1X10 away from the reach of children and pets.
  • Store ONCOTREX 7.5MG TAB 1X10 at room temperature.

Benefits of ONCOTREX 7.5MG TABLET 10'SArrow

  • <b>Treatment of Cancer</b><br>ONCOTREX 7.5MG TABLET 10'S works by slowing down the growth of cancer cells within the body. It is prescribed for treating a diverse array of cancers, including acute leukemias, non-Hodgkin’s lymphoma, and solid tumors located in the breast, lung, bladder, head, and neck, as well as cervical, ovarian, and testicular cancers. This medication may be administered independently or in conjunction with other drugs. It's a powerful and highly toxic medicine, so a thorough discussion of the potential risks and advantages with your healthcare provider is essential. Hydration is key; therefore, it's important to drink plenty of water throughout the treatment period. Simultaneously, avoid alcohol consumption while undergoing this treatment to minimize potential complications and maximize the drug's effectiveness.
  • <b>Treatment of Rheumatoid Arthritis</b><br>ONCOTREX 7.5MG TABLET 10'S is classified as an antimetabolite medication. It's considered for treating severe rheumatoid arthritis, particularly when other treatment options have been exhausted and proven ineffective. It's important to note that it is not typically a first-line treatment. The medicine functions by suppressing the body's immune system, which leads to decreased swelling, reduced pain and stiffness, and improved overall function. It is important to strictly adhere to the prescribed dosage and duration of treatment to achieve optimal results. Avoid exceeding the recommended dosage, and be aware that it may take several months before the full therapeutic effects become apparent.
  • <b>Treatment of Psoriasis</b><br>ONCOTREX 7.5MG TABLET 10'S falls under the category of antimetabolite medications. It may be considered for treating severe psoriasis cases when other treatments have not yielded satisfactory results. Psoriasis is characterized by the excessively rapid growth of skin cells. ONCOTREX 7.5MG TABLET 10'S addresses this by targeting and eliminating these fast-growing cells. Because of its potency and toxicity, it's essential to have a detailed discussion with your doctor about the potential risks and benefits associated with its use. Strictly follow the prescribed dosage and treatment duration for best results. It may require several months to achieve its full effect. During treatment, avoid alcohol and stay well-hydrated by drinking plenty of water.
  • <b>Treatment of Crohn’s Disease</b><br>Crohn’s disease is a long-lasting inflammatory condition affecting the intestines. Common symptoms include diarrhea and abdominal pain. ONCOTREX 7.5MG TABLET 10'S helps to alleviate inflammation, reduce the severity of symptoms, and prevent the recurrence of symptoms, contributing to improved overall well-being and disease management.

How to use ONCOTREX 7.5MG TABLET 10'SArrow

  • Always adhere to your doctor's instructions regarding the dosage and duration of this medicine. It's crucial to follow their recommendations precisely for optimal results and to minimize potential side effects.
  • Administer the tablet orally, swallowing it whole with a glass of water. Avoid any form of alteration such as chewing, crushing, or breaking the tablet, as this can affect how the medication is released and absorbed into your system. The integrity of the tablet ensures that you receive the correct dose in a controlled manner.
  • ONCOTREX 7.5MG TABLET 10'S can be taken either with or without food. If you have a sensitive stomach, taking it with a meal might help reduce discomfort. However, for consistency and to help you remember, it is best to take ONCOTREX 7.5MG TABLET 10'S at the same time each day. This will maintain a steady level of medication in your body, maximizing its effectiveness.
  • If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Consult your healthcare provider if you have any questions or concerns about how to properly take this medication.

Quick Tips for ONCOTREX 7.5MG TABLET 10'SArrow

  • Stay well-hydrated by drinking plenty of fluids while taking this medication. Adequate hydration can help minimize potential side effects and support overall well-being.
  • If your doctor recommends it, take folic acid supplements. Folic acid can help mitigate some of the side effects associated with ONCOTREX 7.5MG TABLET 10'S, improving your tolerance of the medication.
  • It's important to understand that ONCOTREX 7.5MG TABLET 10'S may take several weeks or even months to produce noticeable effects. Consistency is key; continue taking the medication exactly as prescribed by your doctor, even if you don't see immediate results.
  • Your doctor will likely order regular blood tests to monitor your kidney function, liver function, and blood cell levels. These tests are crucial for detecting any potential adverse effects early and ensuring your safety while taking ONCOTREX 7.5MG TABLET 10'S.
  • Avoid consuming alcohol while taking this medicine, as it can significantly increase the risk of experiencing side effects. Alcohol can interact with ONCOTREX 7.5MG TABLET 10'S and potentially worsen its effects on your body.
  • ONCOTREX 7.5MG TABLET 10'S can be harmful to an unborn baby. It is essential to avoid pregnancy for at least six months after your last dose of this medication. Discuss effective contraception methods with your doctor.
  • Store ONCOTREX 7.5MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Proper storage helps maintain the medication's effectiveness.
  • If you experience any unusual or concerning symptoms while taking ONCOTREX 7.5MG TABLET 10'S, such as severe nausea, vomiting, jaundice, or persistent fatigue, contact your doctor immediately.
  • Do not abruptly stop taking ONCOTREX 7.5MG TABLET 10'S without consulting your doctor. Discontinuing the medication suddenly can lead to rebound effects or worsening of your condition.
  • Keep ONCOTREX 7.5MG TABLET 10'S out of reach of children and pets. This medication is intended for your use only and can be harmful if ingested by others.

FAQs

Can ONCOTREX 7.5MG TABLET 10'S cause mouth ulcers?

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Yes, ONCOTREX 7.5MG TABLET 10'S can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Why do I have to take folic acid with ONCOTREX 7.5MG TABLET 10'S?

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Folic acid is required to make new cells in the body and ONCOTREX 7.5MG TABLET 10'S decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of ONCOTREX 7.5MG TABLET 10'S such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.

Why do I need to take regular blood tests while taking ONCOTREX 7.5MG TABLET 10'S?

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Regular blood tests will help your doctor to check your response to ONCOTREX 7.5MG TABLET 10'S and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.

Can ONCOTREX 7.5MG TABLET 10'S use make me more prone to infections?

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ONCOTREX 7.5MG TABLET 10'S may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with ONCOTREX 7.5MG TABLET 10'S use. If you have an active infection, ONCOTREX 7.5MG TABLET 10'S should be used with extreme caution.

Can ONCOTREX 7.5MG TABLET 10'S affect fertility?

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Yes, ONCOTREX 7.5MG TABLET 10'S may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.

What to do if I am planning to become pregnant and my husband is taking ONCOTREX 7.5MG TABLET 10'S?

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You should avoid pregnancy if your husband is taking ONCOTREX 7.5MG TABLET 10'S. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

References

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Methotrexate [Prescribing Information]. Eatontown, NJ: West-Ward Pharmaceuticals Corp.; 2020. (online) Available from:

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Methotrexate [Product Label]. New York, NY: Pfizer Inc.; 2022. (online) Available from:

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Methotrexate [Drug Label]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2022 (online) Available from:

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Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease. [Updated Sep. 2022]. (online) Available from:

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Crohn's & Colitis, UK. Methotrexate [Information Sheet]. (online) Available from:

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CiplaMed. Methotrexate [Prescribing Information]. [Last Reviewed: Feb 2019]. (online) Available from:

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Marketer / Manufacturer Details

SUN PHARMACEUTICAL INDUSTRIES LTD

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ONCOTREX 7.5MG TAB 1X10 - 9863 - Medkart Pharmacy | Generic Medicines Online - Best Online Pharmacy App

ONCOTREX 7.5MG TABLET 10'S

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₹125.8

15 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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