MEXATE 7.5MG TABLET 4'S
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MEXATE 7.5MG TABLET 4'S
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MEXATE 7.5MG TABLET 4'S

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MEXATE 7.5MG TABLET 4'S

By ZYDUS LIFESCIENCES LIMITED

MRP

135.02

₹114.77

15 % OFF

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Product DetailsArrow

About MEXATE 7.5MG TABLET 4'S

  • MEXATE 7.5MG TABLET 4'S is a medication prescribed for the treatment of various cancers affecting different parts of the body, including the breasts, head, neck, lungs, blood, bone, lymph nodes, and uterus. Additionally, it is used in the management of rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease. It works by slowing the growth of cancer cells and suppressing the immune system in autoimmune conditions.
  • This medication can be administered alone or in conjunction with other medicines, depending on the specific treatment plan determined by your doctor. Adherence to the prescribed dosage is crucial, as exceeding it can lead to serious side effects. It's important to understand that the therapeutic benefits may not be immediately apparent and could take several weeks or months to manifest. Do not discontinue the medication without consulting your doctor.
  • It is strongly advised to abstain from alcohol consumption while taking MEXATE 7.5MG TABLET 4'S, as it can significantly increase the risk of liver damage. Common side effects associated with this medicine include ulcerative stomatitis (mouth sores), hair loss, a decrease in blood cell count, elevated liver enzymes, nausea, and abdominal discomfort. Your doctor may recommend folic acid supplementation to mitigate some of these side effects. If these side effects persist or worsen, promptly inform your doctor. They can provide guidance on managing or preventing these effects.
  • Furthermore, MEXATE 7.5MG TABLET 4'S can weaken your body's ability to fight infections and potentially cause complications related to your blood, liver, or kidneys. To monitor for these potential issues, your doctor may conduct regular blood tests, X-rays, and physical examinations before and during treatment. Before starting MEXATE 7.5MG TABLET 4'S, disclose to your doctor any pre-existing conditions affecting your stomach, liver, or kidneys, as well as any medications you are currently taking to treat infections. It is essential to inform your healthcare team of all medications you are using, as many other medicines can interact with MEXATE 7.5MG TABLET 4'S.
  • This medicine is generally not recommended for use during pregnancy or while breastfeeding, as it carries the risk of harming the developing baby. Discuss alternative treatment options with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of MEXATE 7.5MG TABLET 4'S

  • Treatment of Cancer with MEXATE 7.5MG TABLET 4'S
  • Treatment of Rheumatoid arthritis with MEXATE 7.5MG TABLET 4'S for effective relief
  • Treatment of Psoriasis with MEXATE 7.5MG TABLET 4'S for managing skin conditions
  • Treatment of Crohn’s disease with MEXATE 7.5MG TABLET 4'S to alleviate symptoms

How MEXATE 7.5MG TABLET 4'S Works

  • MEXATE 7.5MG TABLET 4'S works by inhibiting an enzyme called dihydrofolate reductase. This action disrupts cell division processes within the body. By interfering with cell division, the medication also produces anti-inflammatory effects, which is beneficial in managing certain conditions.
  • In the context of cancer treatment, MEXATE 7.5MG TABLET 4'S functions as a cytotoxic agent. It prevents cancer cells from producing DNA, which is essential for their growth and multiplication. By halting DNA synthesis, the tablet effectively kills cancer cells.
  • For individuals with psoriasis, MEXATE 7.5MG TABLET 4'S helps manage the condition by slowing down the excessive production of skin cells, a hallmark of psoriasis. Additionally, it works to suppress inflammation in the skin, providing relief from associated symptoms.
  • In rheumatoid arthritis, MEXATE 7.5MG TABLET 4'S acts as an immunosuppressant. It dampens the activity of the immune system, preventing it from mistakenly attacking the body's own cells. This reduction in immune activity helps to alleviate inflammation, which is the underlying cause of swollen and stiff joints in rheumatoid arthritis. It can also prevent damage to the bowel in conditions like Crohn's disease by modulating the immune response.
  • Therefore, MEXATE 7.5MG TABLET 4'S is effective in managing a variety of conditions, due to its multifaceted mechanisms of action, including anti-inflammatory, cytotoxic, and immunosuppressant effects. It is crucial to follow the prescribed dosage and consult with a healthcare professional for appropriate use and management.

Side Effects of MEXATE 7.5MG TABLET 4'SArrow

Most side effects are temporary and disappear as your body adjusts to the medication. Consult your doctor if they persist or if you’re concerned about them.

  • Ulcerative stomatitis
  • Nausea
  • Abdominal pain
  • Increased liver enzymes
  • Hair loss
  • Decreased blood cells (red cells, white cells, and platelets)

Safety Advice for MEXATE 7.5MG TABLET 4'SArrow

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Liver Function

Caution

MEXATE 7.5MG TABLET 4'S should be used with caution in patients with liver disease. Dose adjustment of MEXATE 7.5MG TABLET 4'S may be needed. Please consult your doctor.

Dosage of MEXATE 7.5MG TABLET 4'SArrow

  • For Children: The dosage for children is based on their body surface area (BSA) or weight. Typically, the starting dose ranges from 10 to 20 mg/m² per week, divided into several smaller doses. The dosage may be adjusted based on the child's response to treatment and any potential side effects.
  • For Adults: For adults, the dosage of MEXATE 7.5MG TABLET 4'S can vary depending on the condition being treated. For certain cancers, the typical starting dose ranges from 10 to 25 mg/m² per week, divided into several smaller doses. In the case of rheumatoid arthritis, the initial dosage is often lower, usually starting with 7.5 mg per week, which may be increased gradually.

How to store MEXATE 7.5MG TABLET 4'S?Arrow

  • Keep MEXATE 7.5MG TAB 1X4 away from the reach of children and pets.
  • Store MEXATE 7.5MG TAB 1X4 at room temperature.

Benefits of MEXATE 7.5MG TABLET 4'SArrow

  • **Treatment of Cancer:** MEXATE 7.5MG TABLET 4'S is a medication that slows down the growth of cancer cells. It's used to treat various cancers, including acute leukemias, non-Hodgkin’s lymphoma, and solid tumors in the breast, lung, bladder, head, neck, cervix, ovaries, and testicles. It can be used alone or with other medications. Because it's a strong and toxic medicine, it's important to discuss the risks and benefits with your doctor. Avoid alcohol during treatment and drink plenty of water to stay hydrated. Your doctor will monitor your condition closely during treatment.
  • **Treatment of Rheumatoid Arthritis:** MEXATE 7.5MG TABLET 4'S is an antimetabolite used for severe rheumatoid arthritis when other treatments haven't worked. It's not a first-line treatment. It reduces the body's immune system, which decreases swelling, pain, and stiffness, improving function. Take it exactly as prescribed for the best results, and don't exceed the recommended dose. It may take several months to see the full effects. Regular blood tests will be necessary to monitor your liver and kidney function.
  • **Treatment of Psoriasis:** MEXATE 7.5MG TABLET 4'S is an antimetabolite used for severe psoriasis when other treatments haven't worked. Psoriasis causes skin cells to grow too quickly, and MEXATE 7.5MG TABLET 4'S kills these fast-growing cells. It's a potent and toxic medicine, so discuss the risks and benefits with your doctor. Take it exactly as prescribed, and don't exceed the recommended dose. It may take several months to become fully effective. Avoid alcohol during treatment and drink plenty of water to stay hydrated. Regular eye exams are also recommended while taking this medication.
  • **Treatment of Crohn’s Disease:** Crohn’s disease is a chronic inflammatory disease of the intestines, with common symptoms like diarrhea and abdominal pain. MEXATE 7.5MG TABLET 4'S helps reduce inflammation, relieve symptoms, and prevent them from recurring. It can significantly improve the quality of life for individuals with Crohn's disease. Adhering to the prescribed dosage is essential for managing the condition effectively.

How to use MEXATE 7.5MG TABLET 4'SArrow

  • Always adhere to your doctor's instructions regarding the dosage and duration of MEXATE 7.5MG TABLET 4'S. It's crucial to follow their guidance for optimal results and to minimize potential side effects.
  • Administer the tablet orally, swallowing it whole with a glass of water. Avoid altering the tablet's form by chewing, crushing, or breaking it, as this could affect how the medication is absorbed into your system.
  • MEXATE 7.5MG TABLET 4'S can be taken either with or without food. However, for consistency and to help you remember, it is advisable to take it at the same time each day. This establishes a routine and ensures a steady level of medication in your body. If you experience any stomach upset, taking it with food might be beneficial. Consult your doctor or pharmacist if you have any concerns about how to take this medication.
  • Do not abruptly stop taking this medication without consulting your doctor. Discontinuing the medication suddenly can lead to unwanted complications. It's best to discuss any concerns or side effects you are experiencing with your doctor before making any changes to your treatment plan.

Quick Tips for MEXATE 7.5MG TABLET 4'SArrow

  • Stay hydrated by drinking plenty of fluids while taking this medication. Adequate hydration can help minimize potential side effects and support overall well-being during treatment.
  • If your doctor advises, take folic acid supplements. Folic acid can help mitigate some of the side effects associated with this medicine, improving your tolerance and comfort.
  • It's important to understand that MEXATE 7.5MG TABLET 4'S may take several weeks to months to show its full effects. Be patient and continue taking the medication as prescribed by your doctor, even if you don't notice immediate improvements.
  • Your doctor will likely order regular blood tests to monitor your kidney function, liver function, and blood cell levels. These tests are essential to ensure the medication is working safely and effectively for you.
  • Avoid consuming alcohol while taking this medicine, as it can increase the risk of experiencing adverse side effects. Combining alcohol with this medication can put extra strain on your liver and potentially lead to complications.
  • This medication can be harmful to an unborn baby. Therefore, it's crucial to avoid pregnancy for at least 6 months after your last dose. Use effective contraception to prevent unintended pregnancy during and after treatment.

FAQs

Can MEXATE 7.5MG TABLET 4'S cause mouth ulcers?

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Yes, MEXATE 7.5MG TABLET 4'S can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Why do I have to take folic acid with MEXATE 7.5MG TABLET 4'S?

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Folic acid is required to make new cells in the body and MEXATE 7.5MG TABLET 4'S decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of MEXATE 7.5MG TABLET 4'S such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.

Why do I need to take regular blood tests while taking MEXATE 7.5MG TABLET 4'S?

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Regular blood tests will help your doctor to check your response to MEXATE 7.5MG TABLET 4'S and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.

Can MEXATE 7.5MG TABLET 4'S use make me more prone to infections?

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MEXATE 7.5MG TABLET 4'S may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with MEXATE 7.5MG TABLET 4'S use. If you have an active infection, MEXATE 7.5MG TABLET 4'S should be used with extreme caution.

Can MEXATE 7.5MG TABLET 4'S affect fertility?

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Yes, MEXATE 7.5MG TABLET 4'S may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.

What to do if I am planning to become pregnant and my husband is taking MEXATE 7.5MG TABLET 4'S?

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You should avoid pregnancy if your husband is taking MEXATE 7.5MG TABLET 4'S. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

References

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Methotrexate [Prescribing Information]. Eatontown, NJ: West-Ward Pharmaceuticals Corp.; 2020. (online) Available from:

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Methotrexate [Product Label]. New York, NY: Pfizer Inc.; 2022. (online) Available from:

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Methotrexate [Drug Label]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2022 (online) Available from:

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Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease. [Updated Sep. 2022]. (online) Available from:

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Crohn's & Colitis, UK. Methotrexate [Information Sheet]. (online) Available from:

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CiplaMed. Methotrexate [Prescribing Information]. [Last Reviewed: Feb 2019]. (online) Available from:

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Ratings & Review

Super

Elvis

Reviewed on 25-01-2024

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(5/5)

Good staff and all generic medicines are available.👍

DALPAT PARMAR

Reviewed on 19-01-2024

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(5/5)

Medicines available at good discounted rates and it really help the pockets of the customer...even they help in getting medicines when you order and give your number ..

Pashupati Nath Pandey

Reviewed on 03-02-2024

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(5/5)

Best medicines, Timing and behaviour is very good for human beings

Gyan Rathore

Reviewed on 07-08-2023

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(5/5)

Nice experience, always!

Ashutosh Buch

Reviewed on 24-02-2023

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(5/5)


Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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