ONDERO MET 2.5/850MG TABLET 10'S
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ONDERO MET 2.5/850MG TABLET 10'SONDERO MET 2.5/850MG TABLET 10'SONDERO MET 2.5/850MG TABLET 10'SONDERO MET 2.5/850MG TABLET 10'S
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ONDERO MET 2.5/850MG TABLET 10'S

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ONDERO MET 2.5/850MG TABLET 10'S

By LUPIN LIMITED

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148.5

₹126.22

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About ONDERO MET 2.5/850MG TABLET 10'S

  • ONDERO MET 2.5/850MG TABLET is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes. It contains two active ingredients: linagliptin and metformin hydrochloride. Linagliptin belongs to a class of drugs called DPP-4 inhibitors, which work by increasing the amount of insulin released by the pancreas after meals and decreasing the amount of glucose produced by the liver. Metformin, on the other hand, is a biguanide that reduces glucose production in the liver and improves insulin sensitivity in the body's tissues.
  • This dual-action approach makes ONDERO MET an effective option for individuals who require more than one medication to control their blood sugar. By targeting different pathways involved in glucose regulation, ONDERO MET helps to achieve better glycemic control compared to using either medication alone. It is typically prescribed when diet and exercise are not sufficient to manage blood sugar levels effectively.
  • ONDERO MET 2.5/850MG is usually taken orally once or twice daily with meals, as directed by your healthcare provider. The dosage is individualized based on the patient's specific needs and response to treatment. It is important to follow the prescribed dosage and schedule carefully. Regular monitoring of blood sugar levels is essential while taking this medication to assess its effectiveness and make any necessary adjustments to the treatment plan. This medication should be used in conjunction with a healthy diet and regular physical activity to achieve optimal results in managing type 2 diabetes.
  • Before starting ONDERO MET, it's important to inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart disease, or a history of pancreatitis. Also, discuss any other medications you are currently taking, including over-the-counter drugs and herbal supplements, as they may interact with ONDERO MET. Common side effects may include gastrointestinal symptoms such as nausea, diarrhea, or abdominal discomfort. If you experience any severe or persistent side effects, seek medical attention promptly.

Uses of ONDERO MET 2.5/850MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Improvement of glycemic control
  • Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.

How ONDERO MET 2.5/850MG TABLET 10'S Works

  • ONDERO MET 2.5/850MG TABLET is a combination medication containing two active ingredients: linagliptin and metformin. These two medications work together through different mechanisms to help lower blood sugar levels in individuals with type 2 diabetes. Linagliptin belongs to a class of drugs called DPP-4 inhibitors, while metformin is a biguanide.
  • Linagliptin works by increasing the amount of incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1), are released by the gut after a meal. These hormones stimulate the pancreas to release insulin and reduce the amount of glucose produced by the liver. Linagliptin inhibits the enzyme DPP-4 (dipeptidyl peptidase-4), which breaks down incretin hormones. By inhibiting DPP-4, linagliptin prolongs the activity of incretin hormones, leading to increased insulin release and decreased glucose production when blood sugar levels are high. This helps to lower post-meal blood sugar spikes.
  • Metformin works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. In the liver, metformin reduces the production of glucose by inhibiting gluconeogenesis (the process of making glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, metformin enhances insulin sensitivity in peripheral tissues, such as muscle and fat, allowing cells to utilize glucose more effectively. This means that the body needs less insulin to achieve the same blood sugar control. Metformin also slows down the absorption of glucose from the intestines after a meal, which can further help to reduce post-meal blood sugar spikes.
  • By combining linagliptin and metformin, ONDERO MET 2.5/850MG TABLET provides a dual approach to managing blood sugar levels. Linagliptin helps to increase insulin release and decrease glucose production in response to meals, while metformin reduces glucose production in the liver, improves insulin sensitivity, and slows down glucose absorption. This combination can lead to better blood sugar control than either medication alone. It's important to note that ONDERO MET is most effective when used in conjunction with a healthy diet and regular exercise.
  • The 2.5/850mg dosage indicates that each tablet contains 2.5mg of linagliptin and 850mg of metformin hydrochloride. Patients should take ONDERO MET as prescribed by their doctor, usually once or twice daily with meals, to minimize gastrointestinal side effects. Regular monitoring of blood sugar levels is crucial while taking this medication to ensure that blood sugar levels are well-controlled and to detect any potential side effects.
  • In summary, ONDERO MET 2.5/850MG TABLET combines the actions of linagliptin, which enhances incretin hormone activity, and metformin, which reduces liver glucose production and improves insulin sensitivity. This dual mechanism helps to effectively lower blood sugar levels in individuals with type 2 diabetes, especially when combined with lifestyle modifications.

Side Effects of ONDERO MET 2.5/850MG TABLET 10'SArrow

Common side effects of ONDERO MET 2.5/850MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and metallic taste. Less common but potentially serious side effects include lactic acidosis (symptoms may include rapid breathing, nausea, vomiting, and abdominal pain), hypoglycemia (low blood sugar, symptoms may include sweating, shaking, rapid heartbeat, and confusion), and allergic reactions (rash, itching, swelling). Other possible side effects are headache, dizziness and upper respiratory tract infection. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for ONDERO MET 2.5/850MG TABLET 10'SArrow

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Allergies

Allergies

Do not use ONDERO MET 2.5/850MG TABLET 10'S if you are allergic to it.

Dosage of ONDERO MET 2.5/850MG TABLET 10'SArrow

  • The recommended dosage of ONDERO MET 2.5/850MG TABLET 10'S depends on individual patient needs, blood glucose control, and tolerability. Your doctor will determine the appropriate dose for you based on these factors. Typically, the starting dose is one tablet once or twice daily, taken with meals to reduce gastrointestinal side effects. The maximum daily dose should not exceed the maximum recommended daily dose of linagliptin (5mg) and metformin (2550mg).
  • Dosage adjustments are made gradually based on the patient's glycemic response. Your doctor will monitor your blood sugar levels regularly and adjust your dosage accordingly. It is crucial to follow your doctor's instructions carefully and not to change your dosage without consulting them. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It's important to maintain a consistent dosing schedule to ensure optimal blood sugar control. Taking the medication at the same time(s) each day can help you remember to take it and also maintain steady levels of the medication in your bloodstream. Always swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet. Combining ONDERO MET 2.5/850MG TABLET 10'S with a healthy diet and regular exercise will further enhance its effectiveness in managing your blood sugar levels. Take 'ONDERO MET 2.5/850MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of ONDERO MET 2.5/850MG TABLET 10'S?Arrow

  • If you miss a dose of ONDERO MET 2.5/850MG TABLET 10'S, take it as soon as you remember. However, if it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for the missed one.

How to store ONDERO MET 2.5/850MG TABLET 10'S?Arrow

  • Keep ONDERO MET 2.5/850MG TAB 1X10 away from the reach of children and pets.
  • Store ONDERO MET 2.5/850MG TAB 1X10 at room temperature.

Benefits of ONDERO MET 2.5/850MG TABLET 10'SArrow

  • ONDERO MET 2.5/850MG TABLET 10'S offers a dual-action approach to managing type 2 diabetes, combining a DPP-4 inhibitor (Onglyza - Saxagliptin) with a biguanide (Metformin). This synergistic combination provides comprehensive glycemic control by addressing multiple facets of the disease.
  • Metformin, a cornerstone in type 2 diabetes treatment, primarily works by reducing glucose production in the liver and improving the body's sensitivity to insulin. This helps lower both fasting and postprandial (after-meal) blood sugar levels. By decreasing hepatic glucose output, Metformin prevents the liver from releasing excessive sugar into the bloodstream, thus contributing to better overall glucose control. Furthermore, it enhances insulin sensitivity, allowing cells to utilize glucose more effectively.
  • Saxagliptin, a DPP-4 inhibitor, enhances the incretin system, which plays a crucial role in regulating blood sugar. Incretin hormones, released after meals, stimulate insulin release and suppress glucagon secretion. DPP-4 inhibitors like Saxagliptin prevent the breakdown of these incretin hormones, prolonging their activity and amplifying their beneficial effects on blood sugar levels. This mechanism helps to improve postprandial glucose control and reduce the risk of hypoglycemia (low blood sugar).
  • The combination of Metformin and Saxagliptin in ONDERO MET provides several key benefits. Firstly, it offers superior glycemic control compared to either medication used alone. This is particularly important for individuals who are not achieving adequate blood sugar control with Metformin alone. Secondly, Saxagliptin's mechanism of action is associated with a low risk of hypoglycemia when used as part of this combination therapy. Thirdly, ONDERO MET can potentially lead to weight neutrality or even modest weight loss, which is a significant advantage for many individuals with type 2 diabetes, as weight management is often a critical aspect of their overall treatment plan.
  • Beyond blood sugar control, ONDERO MET may also offer cardiovascular benefits. Some studies suggest that both Metformin and DPP-4 inhibitors may have favorable effects on cardiovascular health, although more research is ongoing in this area. Effective management of blood sugar is crucial for reducing the long-term complications associated with diabetes, such as heart disease, kidney disease, nerve damage, and vision problems. By helping to maintain stable blood sugar levels, ONDERO MET contributes to reducing the risk of these serious health issues, improving overall quality of life.
  • ONDERO MET is typically taken once or twice daily with meals, as directed by a healthcare provider. The dosage is individualized based on the patient's specific needs and response to treatment. Regular monitoring of blood sugar levels and kidney function is essential during treatment with ONDERO MET to ensure optimal safety and effectiveness. It is important to note that ONDERO MET is not a substitute for lifestyle modifications, such as diet and exercise, which remain fundamental components of diabetes management. A healthy diet, regular physical activity, and maintaining a healthy weight are all vital for achieving optimal blood sugar control and overall health.

How to use ONDERO MET 2.5/850MG TABLET 10'SArrow

  • ONDERO MET 2.5/850MG TABLET 10'S is a prescription medication used to treat type 2 diabetes mellitus. It combines two active ingredients, linagliptin and metformin, to help control blood sugar levels. To ensure safe and effective use, follow these instructions carefully:
  • 1. **Dosage:** Always take ONDERO MET exactly as your doctor prescribes. The usual starting dose is one tablet once or twice daily, depending on your condition and the specific formulation. Do not change the dosage without consulting your doctor.
  • 2. **Timing:** Take ONDERO MET with meals to reduce the likelihood of stomach upset. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet.
  • 3. **Consistency:** It is crucial to take ONDERO MET at the same time(s) each day to maintain consistent blood sugar levels. Use a pill organizer or set a reminder if needed.
  • 4. **Diet and Exercise:** ONDERO MET works best when combined with a healthy diet and regular exercise. Follow the dietary guidelines provided by your doctor or a registered dietitian. Engage in physical activity for at least 30 minutes most days of the week.
  • 5. **Monitoring:** Regularly monitor your blood sugar levels as directed by your doctor. Keep a record of your blood sugar readings and share them with your healthcare provider during appointments.
  • 6. **Missed Dose:** If you miss a dose of ONDERO MET, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • 7. **Storage:** Store ONDERO MET at room temperature, away from heat, light, and moisture. Keep the medication out of reach of children.
  • 8. **Precautions:** Inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. ONDERO MET may interact with certain medications. Also, tell your doctor if you have any kidney or liver problems, heart disease, or a history of pancreatitis.
  • 9. **Side Effects:** Common side effects of ONDERO MET may include nausea, vomiting, diarrhea, and abdominal pain. If these side effects persist or worsen, contact your doctor. Serious side effects are rare but can include lactic acidosis (a buildup of lactic acid in the blood) and pancreatitis. Seek immediate medical attention if you experience symptoms such as severe abdominal pain, persistent nausea or vomiting, rapid breathing, or dizziness.
  • 10. **Regular Check-ups:** Attend all scheduled appointments with your doctor for regular check-ups and monitoring. Your doctor may adjust your dosage of ONDERO MET based on your blood sugar levels and overall health.
  • By following these guidelines, you can maximize the benefits of ONDERO MET and effectively manage your type 2 diabetes. Always consult your healthcare provider for personalized advice and guidance.

Quick Tips for ONDERO MET 2.5/850MG TABLET 10'SArrow

  • Take ONDERO MET 2.5/850MG TABLET 10'S as prescribed by your doctor. It's usually taken once or twice daily with meals to minimize stomach upset. Consistency is key, so try to take it at the same time(s) each day to maintain stable blood sugar levels.
  • ONDERO MET 2.5/850MG TABLET 10'S contains both a DPP-4 inhibitor (alogliptin) and biguanide (metformin). These medications work together to lower blood sugar by increasing insulin release, decreasing glucose production in the liver and improving your body's sensitivity to insulin. Follow your diet and exercise plan as instructed by your doctor or diabetes educator for best results.
  • Regular blood sugar monitoring is essential while taking ONDERO MET 2.5/850MG TABLET 10'S. Keep a log of your blood sugar readings and share them with your doctor during your appointments. This will help them assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as shakiness, sweating, dizziness, rapid heartbeat, and confusion. Always carry a source of fast-acting sugar with you, such as glucose tablets, hard candy, or fruit juice, to treat hypoglycemia quickly. Inform your family and friends about the symptoms of hypoglycemia and how to help you if you experience them.
  • Before starting ONDERO MET 2.5/850MG TABLET 10'S, inform your doctor about any other medical conditions you have, especially kidney or liver problems, heart failure, or pancreatitis. Also, tell them about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions. Do not consume excessive alcohol while taking this medicine as it may increase the risk of lactic acidosis, a rare but serious side effect.
  • If you are scheduled for any surgery or medical procedure involving contrast dye, inform your doctor that you are taking ONDERO MET 2.5/850MG TABLET 10'S. They may advise you to temporarily discontinue the medication before the procedure to protect your kidneys.

Food Interactions with ONDERO MET 2.5/850MG TABLET 10'SArrow

  • ONDEO MET 2.5/850MG TABLET 10'S is generally recommended to be taken with meals to help reduce stomach upset caused by metformin, one of its active ingredients. Consistent timing with meals also helps maintain steady blood sugar levels.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a rare but serious side effect of metformin.

FAQs

What is the use of ONDERO MET 2.5/850MG TABLET?Arrow

ONDERO MET 2.5/850MG TABLET is used to treat type 2 diabetes mellitus. It helps control blood sugar levels.

How does ONDERO MET 2.5/850MG TABLET work?Arrow

ONDERO MET 2.5/850MG TABLET is a combination of two medicines: Metformin and Linagliptin. Metformin decreases glucose production in the liver and improves insulin sensitivity, while Linagliptin increases insulin secretion and lowers glucose levels.

What are the common side effects of ONDERO MET 2.5/850MG TABLET?Arrow

Common side effects of ONDERO MET 2.5/850MG TABLET include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is ONDERO MET 2.5/850MG TABLET safe for patients with kidney disease?Arrow

ONDERO MET 2.5/850MG TABLET should be used with caution in patients with kidney disease. Dose adjustments may be necessary, or the medication may not be suitable.

Is ONDERO MET 2.5/850MG TABLET safe during pregnancy?Arrow

The safety of ONDERO MET 2.5/850MG TABLET during pregnancy has not been established. It should be used only when clearly needed and under the advice of a doctor.

How to store ONDERO MET 2.5/850MG TABLET?Arrow

Store ONDERO MET 2.5/850MG TABLET at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Is it safe to consume alcohol with ONDERO MET 2.5/850MG TABLET?Arrow

Alcohol consumption should be avoided with ONDERO MET 2.5/850MG TABLET as it can lower blood sugar levels and increase other side effects.

Can ONDERO MET 2.5/850MG TABLET interact with other medications?Arrow

ONDERO MET 2.5/850MG TABLET can interact with certain medications, such as insulin, sulfonylureas, and some antibiotics. Inform your doctor about all the medications you are taking.

What happens if I miss a dose of ONDERO MET 2.5/850MG TABLET?Arrow

If you miss a dose of ONDERO MET 2.5/850MG TABLET, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and follow your regular dosing schedule.

Should ONDERO MET 2.5/850MG TABLET be taken with food?Arrow

It is recommended to take ONDERO MET 2.5/850MG TABLET with food to minimize the chance of stomach upset.

Does ONDERO MET 2.5/850MG TABLET cause weight gain?Arrow

ONDERO MET 2.5/850MG TABLET does not usually cause weight gain. However, in some patients, it may lead to weight gain due to increased appetite or other factors.

What should I avoid while taking ONDERO MET 2.5/850MG TABLET?Arrow

While taking ONDERO MET 2.5/850MG TABLET, avoid alcohol, excessive exercise, and monitor your blood sugar levels regularly.

Can I break or chew ONDERO MET 2.5/850MG TABLET?Arrow

ONDERO MET 2.5/850MG TABLET should be swallowed whole and should not be broken or chewed.

What to do in case of an overdose of ONDERO MET 2.5/850MG TABLET?Arrow

In case of an overdose of ONDERO MET 2.5/850MG TABLET, contact a doctor immediately or go to the nearest hospital.

How long does it take for ONDERO MET 2.5/850MG TABLET to show its effect?Arrow

It may take a few days or weeks for ONDERO MET 2.5/850MG TABLET to show its effect. It can vary from person to person.

References

Book Icon

FDA - ONGLYZA (saxagliptin) and metformin hydrochloride tablet, film coated. This document provides detailed information on the drug, including its pharmacology, clinical studies, and safety information. It contains technical information relevant to the drug's ingredients and formulation.

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DrugBank - Saxagliptin. A detailed drug entry for saxagliptin providing chemical structure, mechanism of action, metabolism, and drug interactions. It includes research and technical data.

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DrugBank - Metformin. A detailed drug entry for metformin providing chemical structure, mechanism of action, metabolism, and drug interactions. It includes research and technical data.

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National Center for Biotechnology Information (NCBI) - Efficacy and safety of saxagliptin added to metformin in Asian patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy: a randomized, double-blind, placebo-controlled study. This research article details a clinical trial on the use of saxagliptin in combination with metformin.

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European Medicines Agency (EMA) - Komboglyze. Komboglyze is a medicine containing two active substances, saxagliptin and metformin. It is used together with diet and exercise to improve blood glucose (sugar) control in adults with type 2 diabetes. This provides technical details from the EMA's assessment.

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LUPIN LIMITED

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ONDERO MET 2.5/850MG TABLET 10'S

ONDERO MET 2.5/850MG TABLET 10'S

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