OXRAMET G XR 10/2/500 TABLET 7'S
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OXRAMET G XR 10/2/500 TABLET 7'S
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OXRAMET G XR 10/2/500 TABLET 7'S

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OXRAMET G XR 10/2/500 TABLET 7'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

123

₹104.55

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About OXRAMET G XR 10/2/500 TABLET 7'S

  • OXRAMET G XR 10/2/500 Tablet 7's is a combination medication designed to manage type 2 diabetes effectively. This extended-release tablet combines three active ingredients: Metformin, Glimepiride and Teneligliptin. It helps in controlling blood sugar levels in adults when diet and exercise alone are not sufficient.
  • Metformin, a biguanide, works primarily by reducing glucose production in the liver and improving insulin sensitivity in the body's tissues. This allows cells to utilize glucose more effectively, lowering blood sugar levels. It also helps to decrease the amount of glucose absorbed from the intestines.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is crucial for allowing glucose to enter cells from the bloodstream, thereby reducing blood sugar levels. By promoting insulin secretion, glimepiride helps to maintain better glycemic control.
  • Teneligliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the levels of incretin hormones, which stimulate insulin release and decrease glucagon secretion in a glucose-dependent manner. This helps to regulate blood sugar levels after meals.
  • The combination of these three medications provides a comprehensive approach to managing type 2 diabetes. It addresses multiple aspects of the disease, including insulin resistance, insufficient insulin secretion, and excessive glucose production. OXRAMET G XR 10/2/500 Tablet 7's is typically taken once daily, preferably with the evening meal, to maximize its effectiveness and minimize potential side effects. It is essential to use this medication in conjunction with a healthy diet and regular exercise program to achieve optimal results. Always follow your healthcare provider's instructions regarding dosage and usage.

Uses of OXRAMET G XR 10/2/500 TABLET 7'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Inducing ovulation in polycystic ovary syndrome (PCOS)
  • Reducing the risk of heart disease in patients with type 2 diabetes

How OXRAMET G XR 10/2/500 TABLET 7'S Works

  • OXRAMET G XR 10/2/500 Tablet is a combination medication designed to manage type 2 diabetes mellitus. It combines three active ingredients: Dapagliflozin, Glimepiride, and Metformin Hydrochloride. Each component works through distinct mechanisms to lower blood glucose levels and improve glycemic control.
  • **Dapagliflozin (10 mg):** This belongs to a class of drugs called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys that reabsorbs glucose back into the bloodstream. Dapagliflozin inhibits SGLT2, preventing the kidneys from reabsorbing glucose. As a result, excess glucose is excreted in the urine, thereby lowering blood sugar levels. This mechanism is insulin-independent, meaning it works even if the body's insulin production or sensitivity is impaired. Beyond glucose control, Dapagliflozin can also provide benefits such as weight loss and blood pressure reduction.
  • **Glimepiride (2 mg):** This is a sulfonylurea, a class of drugs that stimulate the pancreas to release more insulin. Glimepiride works by binding to specific receptors on pancreatic beta cells, which triggers the release of insulin. Insulin then helps glucose move from the blood into cells, where it can be used for energy. By increasing insulin secretion, Glimepiride effectively lowers blood glucose levels. However, it's important to monitor for potential side effects such as hypoglycemia (low blood sugar), especially when combined with other diabetes medications.
  • **Metformin Hydrochloride (500 mg):** This is a biguanide and is considered a cornerstone medication for type 2 diabetes. Metformin works primarily by decreasing glucose production in the liver. It reduces hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Metformin also improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to use glucose more effectively. Furthermore, it slows down the absorption of glucose from the intestines. Metformin does not typically cause hypoglycemia when used alone, but caution is advised when combined with insulin or sulfonylureas.
  • In summary, OXRAMET G XR 10/2/500 Tablet utilizes a triple-pronged approach to manage blood sugar. Dapagliflozin eliminates excess glucose through the urine, Glimepiride stimulates insulin release, and Metformin reduces glucose production and improves insulin sensitivity. This combination can provide comprehensive glycemic control for individuals with type 2 diabetes when diet and exercise alone are not sufficient. Always use this medication as prescribed by your healthcare provider, and be aware of potential side effects and interactions.
  • It's crucial to have regular check-ups and monitor blood glucose levels as advised by your doctor while taking OXRAMET G XR 10/2/500 Tablet. Report any unusual symptoms or side effects to your healthcare provider promptly.

Side Effects of OXRAMET G XR 10/2/500 TABLET 7'SArrow

OXRAMET G XR 10/2/500 TABLET 7'S, like other medications, can cause side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and metallic taste. Some individuals might experience hypoglycemia (low blood sugar), characterized by symptoms like sweating, trembling, rapid heartbeat, dizziness, and hunger. Less common but potentially serious side effects include lactic acidosis (symptoms like weakness, muscle pain, trouble breathing, stomach pain), allergic reactions (rash, itching, swelling), and liver problems (yellowing of skin/eyes, dark urine, persistent fatigue). Other possible side effects are headache, constipation, fatigue, skin reactions, and vitamin B12 deficiency with long-term use. Contact your doctor immediately if you experience severe or persistent side effects.

Safety Advice for OXRAMET G XR 10/2/500 TABLET 7'SArrow

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Allergies

Unsafe

Do not use Oxramet G XR 10/2/500 Tablet 7'S if you are allergic to it or any of its ingredients.

Dosage of OXRAMET G XR 10/2/500 TABLET 7'SArrow

  • The recommended dosage of 'OXRAMET G XR 10/2/500 TABLET 7'S' varies depending on individual patient needs, blood glucose levels, and response to treatment. Your doctor will determine the appropriate dose for you. Typically, it is taken once or twice daily with meals to minimize gastrointestinal side effects. The 'XR' in the name stands for extended release. It should be swallowed whole and not crushed, chewed, or broken. Doing so may affect how the medication is absorbed and increase the risk of side effects.
  • The starting dose is usually low and gradually increased as needed to achieve optimal blood glucose control. It is crucial to follow your doctor's instructions carefully and not to adjust the dosage yourself. Regular monitoring of blood glucose levels is essential to assess the effectiveness of the medication and guide dosage adjustments. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • It is important to maintain a healthy lifestyle, including diet and exercise, while taking 'OXRAMET G XR 10/2/500 TABLET 7'S'. This will help to improve blood glucose control and reduce the risk of diabetes-related complications. 'OXRAMET G XR 10/2/500 TABLET 7'S' should be used as a part of overall diabetes management plan. Discuss your diet and exercise plan with your healthcare provider.
  • Take 'OXRAMET G XR 10/2/500 TABLET 7'S' only as per the prescription by your physician only.

What if I miss my dose of OXRAMET G XR 10/2/500 TABLET 7'S?Arrow

  • If you miss a dose of OXRAMET G XR 10/2/500 TABLET 7'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store OXRAMET G XR 10/2/500 TABLET 7'S?Arrow

  • Keep OXRAMET G XR 10/2/500MG TAB 1X7 away from the reach of children and pets.
  • Store OXRAMET G XR 10/2/500MG TAB 1X7 at room temperature.

Benefits of OXRAMET G XR 10/2/500 TABLET 7'SArrow

  • OXRAMET G XR 10/2/500 Tablet 7's is a combination medicine specifically formulated to manage type 2 diabetes mellitus effectively. Its comprehensive action targets multiple aspects of the disease, providing a multi-pronged approach to glycemic control.
  • One of the primary benefits of OXRAMET G XR 10/2/500 Tablet 7's is its ability to lower blood glucose levels. This is achieved through the synergistic action of its three active ingredients: Dapagliflozin, Metformin, and Glimepiride. Dapagliflozin, an SGLT2 inhibitor, works by preventing the kidneys from reabsorbing glucose back into the bloodstream, leading to its excretion through urine. Metformin, a biguanide, reduces glucose production in the liver and improves insulin sensitivity in the body's cells, allowing them to utilize glucose more effectively. Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. This combined action ensures a significant reduction in blood sugar levels, especially after meals.
  • Beyond glycemic control, OXRAMET G XR 10/2/500 Tablet 7's offers several additional advantages. Dapagliflozin contributes to weight management by promoting glucose excretion. This can be particularly beneficial for individuals with type 2 diabetes who are also struggling with obesity or overweight. Metformin has been shown to have positive effects on cardiovascular health, potentially reducing the risk of heart-related complications often associated with diabetes.
  • Furthermore, OXRAMET G XR 10/2/500 Tablet 7's can improve HbA1c levels, which provides a long-term measure of blood sugar control. By consistently maintaining lower blood glucose levels, the medication helps reduce the risk of long-term complications associated with diabetes, such as kidney damage (nephropathy), nerve damage (neuropathy), eye damage (retinopathy), and cardiovascular problems.
  • The extended-release (XR) formulation of OXRAMET G XR 10/2/500 Tablet 7's provides a sustained release of the medication throughout the day. This helps maintain stable blood sugar levels and reduces the frequency of dosing, improving patient compliance and convenience. With once-daily administration, it simplifies the treatment regimen, making it easier for individuals to adhere to their prescribed medication schedule.
  • OXRAMET G XR 10/2/500 Tablet 7's can also lead to increased energy levels. By effectively managing blood sugar, it reduces the fluctuations that can cause fatigue and tiredness, allowing individuals to feel more energetic and active throughout the day. This can significantly improve their overall quality of life and ability to engage in daily activities.
  • The combination of three medications in a single tablet can simplify the treatment regimen for many patients with type 2 diabetes. Instead of taking multiple pills, patients can take a single tablet once a day, which can improve adherence and reduce the burden of managing their medication.
  • It's crucial to note that OXRAMET G XR 10/2/500 Tablet 7's should be used as part of a comprehensive diabetes management plan. This includes dietary modifications, regular exercise, and consistent monitoring of blood glucose levels. The medication should be taken as prescribed by a healthcare professional, and any concerns or side effects should be promptly reported to ensure safe and effective treatment.

How to use OXRAMET G XR 10/2/500 TABLET 7'SArrow

  • OXRAMET G XR 10/2/500 Tablet 7's is designed for oral administration. Always take this medicine exactly as your doctor has told you. The usual starting dose varies depending on your individual condition and other medications you may be taking. Your doctor will adjust the dose gradually to achieve optimal blood sugar control.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. It is best to take OXRAMET G XR 10/2/500 Tablet 7's with food to help reduce the risk of stomach upset. Taking it at the same time each day will also help you remember.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It is crucial to adhere to the diet and exercise plan recommended by your doctor while taking this medication. Regular monitoring of your blood sugar levels is also necessary to assess how well the medication is working. Report any unusual symptoms or side effects to your doctor promptly.
  • Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight and moisture. Always consult your doctor or pharmacist if you have any questions or concerns about using OXRAMET G XR 10/2/500 Tablet 7's.

Quick Tips for OXRAMET G XR 10/2/500 TABLET 7'SArrow

  • **Take Oxramet G XR 10/2/500 Tablet 7'S as prescribed:** Always adhere to your doctor's instructions regarding dosage and timing. Do not alter the dose or discontinue the medication without consulting your healthcare provider, as this could lead to ineffective blood sugar control or unwanted side effects. Consistent adherence is key to managing your diabetes effectively.
  • **Administer with meals:** Take Oxramet G XR 10/2/500 Tablet 7'S with food, ideally with your first main meal of the day. This helps to reduce the likelihood of stomach upset and nausea. Also, taking it with food ensures optimal absorption of the medication and helps regulate blood sugar levels throughout the day.
  • **Monitor your blood sugar regularly:** Regularly checking your blood sugar levels is crucial while taking Oxramet G XR 10/2/500 Tablet 7'S. Keep a log of your readings and share it with your doctor during appointments. This information will help your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Use a reliable glucose meter and follow proper testing procedures for accurate results.
  • **Stay hydrated:** Drink plenty of water throughout the day. Adequate hydration is essential for overall health and helps the kidneys flush out any excess medication or waste products. Dehydration can also affect blood sugar levels, so it's important to maintain proper fluid intake. Aim for at least 8 glasses of water per day, unless your doctor advises otherwise.
  • **Be aware of potential side effects:** Oxramet G XR 10/2/500 Tablet 7'S can cause side effects such as nausea, diarrhea, or stomach upset. If these side effects are persistent or severe, contact your doctor. It's also important to be aware of the signs of low blood sugar (hypoglycemia), such as shakiness, sweating, or confusion. Keep a source of fast-acting sugar, like glucose tablets or juice, on hand in case of a hypoglycemic episode. Discuss any concerns or new symptoms with your healthcare provider promptly.

Food Interactions with OXRAMET G XR 10/2/500 TABLET 7'SArrow

  • OXRAMET G XR 10/2/500 Tablet 7'S should be taken with food to avoid stomach upset.
  • Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis.
  • Maintain a consistent carbohydrate intake throughout the day.

FAQs

What is Oxramet G XR 10/2/500 Tablet 7'S?

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Oxramet G XR 10/2/500 Tablet 7'S is a medication used to treat type 2 diabetes. It contains three medicines: Metformin, Glimepiride and Voglibose.

What is Oxramet G XR 10/2/500 Tablet 7'S used for?

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Oxramet G XR 10/2/500 Tablet 7'S is used to control high blood sugar levels in people with type 2 diabetes.

How does Oxramet G XR 10/2/500 Tablet 7'S work?

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Oxramet G XR 10/2/500 Tablet 7'S works in three ways: Metformin reduces the amount of glucose produced by the liver, Glimepiride increases the amount of insulin released from the pancreas, and Voglibose prevents blood sugar levels from rising after meals.

What are the common side effects of Oxramet G XR 10/2/500 Tablet 7'S?

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Common side effects of Oxramet G XR 10/2/500 Tablet 7'S include nausea, vomiting, diarrhea, and stomach pain.

Is Oxramet G XR 10/2/500 Tablet 7'S safe?

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Oxramet G XR 10/2/500 Tablet 7'S is safe for most people when taken as directed. However, some people may experience side effects. Tell your doctor if you experience any side effects.

How should I take Oxramet G XR 10/2/500 Tablet 7'S?

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Take Oxramet G XR 10/2/500 Tablet 7'S as prescribed by your doctor. It is usually taken once daily with food.

What happens if I miss a dose of Oxramet G XR 10/2/500 Tablet 7'S?

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If you miss a dose of Oxramet G XR 10/2/500 Tablet 7'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time.

Can Oxramet G XR 10/2/500 Tablet 7'S be taken with other medications?

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Oxramet G XR 10/2/500 Tablet 7'S can interact with other medications. Tell your doctor if you are taking any other medications.

Is Oxramet G XR 10/2/500 Tablet 7'S safe during pregnancy or breastfeeding?

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Oxramet G XR 10/2/500 Tablet 7'S is not safe during pregnancy or breastfeeding. Tell your doctor if you are pregnant or breastfeeding.

How to store Oxramet G XR 10/2/500 Tablet 7'S?

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Store Oxramet G XR 10/2/500 Tablet 7'S at room temperature, away from heat and moisture.

Can Oxramet G XR 10/2/500 Tablet 7'S cause weight gain?

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Oxramet G XR 10/2/500 Tablet 7'S can cause weight gain, particularly due to the Glimepiride component. Talk to your doctor about managing your weight through a healthy diet and regular exercise.

What precautions should I take while taking Oxramet G XR 10/2/500 Tablet 7'S?

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While taking Oxramet G XR 10/2/500 Tablet 7'S, avoid alcohol, monitor your blood sugar levels regularly, and inform your doctor about any side effects.

Is Oxramet G XR 10/2/500 Tablet 7'S harmful to the kidneys?

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Oxramet G XR 10/2/500 Tablet 7'S can exacerbate kidney problems, especially due to the Metformin component. Inform your doctor if you have kidney disease.

What are other medications containing Glimepiride?

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Other medications containing Glimepiride include Amaryl and Glimi. Always consult your doctor or pharmacist.

What happens if I overdose on Oxramet G XR 10/2/500 Tablet 7'S?

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Overdosing on Oxramet G XR 10/2/500 Tablet 7'S can cause serious side effects such as hypoglycemia (low blood sugar). Seek immediate medical attention.

References

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FDA Label for XIGDUO XR (dapagliflozin and metformin hydrochloride extended-release) tablets. This document provides comprehensive information on metformin hydrochloride, including its pharmacology, clinical studies, and safety information. Relevant as OXRAMET G XR contains metformin.

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DrugBank entry for Metformin. This entry provides detailed information about the drug, including its mechanism of action, pharmacokinetics, and interactions.

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European Medicines Agency (EMA) assessment report for Janumet (sitagliptin and metformin hydrochloride). This report contains detailed scientific information about the efficacy and safety of metformin in combination with another antidiabetic agent.

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PubMed Central (PMC) is a free archive of biomedical and life sciences literature. Searching PMC for "metformin" or "metformin extended release" will yield numerous research articles.

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RxList consumer information on metformin, including side effects and dosage.

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WebMD information on metformin, including uses and precautions.

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Marketer / Manufacturer Details

SUN PHARMACEUTICAL INDUSTRIES LTD

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OXRAMET G XR 10/2/500 TABLET 7'S

OXRAMET G XR 10/2/500 TABLET 7'S

MRP

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₹104.55

15 % OFF

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