oxramet ir 5/1000mg tablet 14's
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OXRAMET IR 5/1000MG TABLET 14'S

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OXRAMET IR 5/1000MG TABLET 14'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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229.69

₹195.24

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Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About OXRAMET IR 5/1000MG TABLET 14'S

  • Oxramet IR 5/1000 mg Tablet is a combination medicine used to help manage blood sugar in adults with type 2 diabetes. It combines two active ingredients — dapagliflozin 5 mg and metformin hydrochloride 1000 mg (sustained release) — that work through different mechanisms to improve glycaemic control when diet and exercise alone are not sufficient.
  • Dapagliflozin belongs to a class of drugs called SGLT2 inhibitors (sodium-glucose co-transporter 2 inhibitors). It works in the kidneys by blocking the reabsorption of glucose, so that excess sugar is removed from the body in the urine. This lowers blood sugar independently of insulin and can also support modest reductions in weight and blood pressure, which is helpful in type 2 diabetes.
  • Metformin is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin, and it also reduces the amount of glucose absorbed from the intestines. Metformin is a cornerstone of type 2 diabetes treatment and is often used as first-line therapy; here it is provided in a sustained-release form, which releases the drug gradually and may be gentler on the stomach.
  • By combining dapagliflozin and metformin, Oxramet IR offers a comprehensive approach to blood-sugar control, addressing glucose removal by the kidneys, glucose production in the liver, and insulin sensitivity together. This can lead to better overall glycaemic control and support the reduction of diabetes-related complications.
  • It is important to take Oxramet IR exactly as prescribed by your doctor, usually with meals, and your doctor may adjust the dose based on your needs, blood sugar levels, and kidney function. Continue a healthy diet and regular exercise while taking it, and stay well hydrated. Potential side effects include nausea, diarrhoea, and abdominal pain; because of the SGLT2 component, genital and urinary infections can occur, and a rare but serious condition called diabetic ketoacidosis is possible. Seek prompt medical attention for symptoms such as unusual tiredness, muscle pain, difficulty breathing, severe stomach pain, or signs of infection, and contact your doctor if any side effects are unusual or persistent.
  • Generic alternative: a generic medicine has the same active composition as the branded product — for Oxramet IR 5/1000mg Tablet 14's that is Dapagliflozin 5 Mg+metformin Hydrochloride 1000 MG Sustained Release. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of OXRAMET IR 5/1000MG TABLET 14'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Management of Polycystic Ovary Syndrome (PCOS) (off-label use)
  • May help reduce the risk of heart disease (in some patients)
  • Aids in weight management (in some patients)

How OXRAMET IR 5/1000MG TABLET 14'S Works

  • OXRAMET IR 5/1000MG TABLET 14'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Metformin and Glimepiride, each working through different mechanisms to achieve optimal glycemic control. Metformin primarily reduces glucose production in the liver, decreasing the amount of sugar released into the bloodstream. It also enhances insulin sensitivity, allowing the body to use insulin more effectively. This dual action helps lower both fasting and post-meal blood sugar levels. Glimepiride, on the other hand, is a sulfonylurea that stimulates the pancreas to release more insulin. By increasing insulin secretion, glimepiride helps the body move glucose from the blood into cells, where it can be used for energy. The combination of Metformin and Glimepiride in OXRAMET IR addresses multiple facets of type 2 diabetes, providing a comprehensive approach to blood sugar management.
  • Specifically, Metformin acts on the liver to suppress gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. By reducing gluconeogenesis, Metformin lowers the liver's contribution to blood sugar levels. Furthermore, Metformin increases the uptake and utilization of glucose in peripheral tissues like muscles, improving insulin sensitivity. This means that cells become more responsive to insulin, allowing them to absorb glucose more efficiently. The impact of Metformin on insulin sensitivity is particularly beneficial for individuals with insulin resistance, a common characteristic of type 2 diabetes. Clinical studies have demonstrated that Metformin can significantly reduce HbA1c levels, a measure of long-term blood sugar control, and improve overall metabolic parameters.
  • Glimepiride's mechanism involves binding to specific receptors on pancreatic beta cells, triggering a cascade of events that lead to insulin secretion. This insulin release is glucose-dependent, meaning that Glimepiride stimulates insulin secretion in response to elevated blood sugar levels. As insulin is released, it facilitates the transport of glucose from the bloodstream into cells, thereby lowering blood sugar levels. Glimepiride is known for its potent effect on insulin secretion, making it effective in controlling postprandial hyperglycemia, the rise in blood sugar levels after meals. However, it's important to note that Glimepiride can potentially cause hypoglycemia (low blood sugar) if not carefully managed, especially when combined with other diabetes medications or dietary changes. The synergistic action of Metformin and Glimepiride in OXRAMET IR provides a balanced approach to blood sugar control, targeting both insulin resistance and insulin deficiency.
  • In essence, OXRAMET IR works by reducing the amount of glucose produced by the liver, increasing the body's sensitivity to insulin, and stimulating the pancreas to release more insulin when blood sugar levels are high. This multifaceted approach helps to maintain stable blood sugar levels throughout the day, reducing the risk of diabetes-related complications. Regular monitoring of blood sugar levels and adherence to a healthy diet and exercise plan are essential components of managing type 2 diabetes with OXRAMET IR.

Side Effects of OXRAMET IR 5/1000MG TABLET 14'SArrow

Common side effects of OXRAMET IR 5/1000MG TABLET may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, and metallic taste. Less common side effects can include skin rash, itching, hypoglycemia (low blood sugar), and vitamin B12 deficiency. In rare cases, serious side effects such as lactic acidosis, liver problems, and allergic reactions may occur. Contact your doctor immediately if you experience symptoms like unexplained muscle pain, difficulty breathing, persistent nausea or vomiting, or yellowing of the skin or eyes.

Safety Advice for OXRAMET IR 5/1000MG TABLET 14'SArrow

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Allergies

Caution

Do not consume Oxramet IR 5/1000mg Tablet 14'S if you are allergic to it.

Dosage of OXRAMET IR 5/1000MG TABLET 14'SArrow

  • The recommended dosage of OXRAMET IR 5/1000MG TABLET 14'S varies depending on individual patient needs, blood glucose levels, and response to treatment. Your doctor will determine the appropriate dose for you. Typically, the starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. The maximum daily dose should not exceed the maximum recommended daily dose of metformin and the specific DPP-4 inhibitor component.
  • The dosage may be gradually increased by your physician based on your blood glucose levels. Regular monitoring of blood glucose is crucial to adjust the dosage effectively. It's important to follow your doctor's instructions precisely and not to change the dose without consulting them. Taking OXRAMET IR 5/1000MG TABLET 14'S at the same time(s) each day will help you remember to take it.
  • If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It is important to maintain a healthy lifestyle, including diet and exercise, while taking OXRAMET IR 5/1000MG TABLET 14'S. This will help to improve blood glucose control and overall health. Consult your doctor or a registered dietitian for personalized advice on diet and exercise.
  • Take 'OXRAMET IR 5/1000MG TABLET 14'S' only as per the prescription by your physician only

What if I miss my dose of OXRAMET IR 5/1000MG TABLET 14'S?Arrow

  • If you miss a dose of OXRAMET IR 5/1000MG TABLET 14'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store OXRAMET IR 5/1000MG TABLET 14'S?Arrow

  • Keep OXRAMET IR 5/1000MG TAB 1X14 away from the reach of children and pets.
  • Store OXRAMET IR 5/1000MG TAB 1X14 at room temperature.

Benefits of OXRAMET IR 5/1000MG TABLET 14'SArrow

  • OXRAMET IR 5/1000MG TABLET 14'S is a combination medication containing two active ingredients: Metformin and a Sulfonylurea (such as Glibenclamide, Glipizide, or Glimepiride). This dual action makes it highly effective in managing type 2 diabetes, particularly when diet and exercise alone are insufficient to control blood sugar levels. Metformin primarily works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues, allowing cells to utilize glucose more effectively. The Sulfonylurea component stimulates the pancreas to release more insulin. This combination addresses multiple facets of type 2 diabetes, providing comprehensive glycemic control.
  • One of the primary benefits of OXRAMET IR is its ability to significantly lower HbA1c levels. HbA1c provides an average measure of blood sugar control over the past 2-3 months. By effectively reducing both fasting and postprandial (after-meal) blood glucose levels, OXRAMET IR helps patients achieve and maintain target HbA1c goals, reducing the risk of long-term complications associated with poorly controlled diabetes. These complications include cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • OXRAMET IR offers a synergistic effect, meaning the combination of Metformin and a Sulfonylurea is more effective than either medication used alone. This synergy allows for better blood sugar control at potentially lower doses of each individual drug, reducing the risk of side effects. The combination also simplifies the treatment regimen for patients who require both medications, as they can take a single tablet instead of multiple pills, enhancing adherence and convenience.
  • Metformin, a key component of OXRAMET IR, has been associated with several additional health benefits beyond glycemic control. It can promote modest weight loss or weight stabilization in some individuals, which is particularly beneficial for overweight or obese patients with type 2 diabetes. Unlike some other diabetes medications, Metformin does not typically cause weight gain and may even help reduce appetite. Furthermore, Metformin has been studied for its potential role in reducing the risk of cardiovascular events and certain types of cancer, although more research is ongoing in these areas.
  • The Sulfonylurea component in OXRAMET IR provides rapid insulin release, which is particularly useful for managing postprandial hyperglycemia (high blood sugar after meals). This helps to normalize blood sugar spikes after eating, preventing symptoms like fatigue, blurred vision, and frequent urination. By effectively managing these spikes, OXRAMET IR contributes to overall glycemic stability throughout the day.
  • OXRAMET IR is a cost-effective treatment option compared to newer, more expensive diabetes medications. This makes it an accessible choice for many patients, particularly in healthcare systems with limited resources. Its established efficacy and safety profile, combined with its affordability, make it a valuable tool in the management of type 2 diabetes.
  • The use of OXRAMET IR, under the guidance of a healthcare professional, can significantly improve the quality of life for individuals with type 2 diabetes. By effectively controlling blood sugar levels, patients can experience reduced symptoms, improved energy levels, and a decreased risk of developing debilitating long-term complications. Regular monitoring and adherence to the prescribed dosage are crucial for maximizing the benefits of OXRAMET IR and minimizing potential side effects.

How to use OXRAMET IR 5/1000MG TABLET 14'SArrow

  • OXRAMET IR 5/1000MG Tablet is an oral medication and should be taken exactly as prescribed by your doctor. It is typically prescribed to be taken with meals to minimize potential stomach upset. The usual starting dose is one tablet, once or twice daily, depending on your individual needs and response to the medication. Your doctor may gradually increase the dosage over time to achieve optimal blood sugar control. Do not exceed the maximum recommended daily dose.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet unless specifically instructed by your doctor, as this can affect how the medication is released into your body. It is crucial to maintain a consistent schedule for taking OXRAMET IR 5/1000MG Tablet, taking it at the same time(s) each day to help maintain stable blood sugar levels. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It is important to adhere to any dietary and exercise recommendations made by your doctor or diabetes educator while taking OXRAMET IR 5/1000MG Tablet. This medication works best when combined with a healthy lifestyle. Regularly monitor your blood sugar levels as directed by your healthcare provider and inform them of any unusual symptoms or side effects you experience. Keep all appointments with your doctor and laboratory for routine check-ups and monitoring. Store OXRAMET IR 5/1000MG Tablet at room temperature, away from moisture and heat, and out of reach of children.

Quick Tips for OXRAMET IR 5/1000MG TABLET 14'SArrow

  • Take OXRAMET IR 5/1000MG Tablet as prescribed by your doctor. It's usually taken with meals to minimize stomach upset. Consistent timing is key – aim to take it at the same time each day to maintain stable blood sugar levels.
  • Don't crush, chew, or break the tablet. Swallow it whole with a full glass of water. This ensures the medication is released properly in your system for optimal effectiveness.
  • Follow your doctor's dietary and exercise recommendations closely while taking OXRAMET IR. This medication works best when combined with a healthy lifestyle. Regular physical activity and a balanced diet will enhance its effectiveness in managing blood sugar.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, and confusion. Keep a source of fast-acting sugar with you, like glucose tablets or fruit juice, in case of a sudden drop. Inform your family and friends about these symptoms and how to help.
  • Inform your doctor about all other medications, supplements, and herbal products you're taking. Certain substances can interact with OXRAMET IR, affecting its efficacy or increasing the risk of side effects. This includes over-the-counter drugs, as well as prescribed medications. Regular check-ups are essential to monitor your progress and manage any potential side effects. Do not abruptly stop this medication without consulting your healthcare provider, as it may lead to fluctuations in your blood sugar levels.

Food Interactions with OXRAMET IR 5/1000MG TABLET 14'SArrow

  • OXRAMET IR 5/1000MG TABLET 14'S should be taken with food to avoid stomach upset.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a rare but serious side effect.
  • There are no specific food items that are known to interact negatively with OXRAMET IR 5/1000MG TABLET 14'S, but maintaining a consistent diet is recommended.

FAQs

What is Oxramet IR 5/1000mg Tablet 14's?Arrow

Oxramet IR 5/1000mg Tablet 14's is a medication containing a combination of Metformin and Oxetacaine, used to treat type 2 diabetes.

What is Oxramet IR 5/1000mg Tablet 14's used for?Arrow

Oxramet IR 5/1000mg Tablet 14's is used to control high blood sugar levels in patients with type 2 diabetes.

How does Oxramet IR 5/1000mg Tablet 14's work?Arrow

Oxramet IR 5/1000mg Tablet 14's works through the combination of two drugs: Metformin, which reduces glucose production in the liver, and Oxetacaine, which neutralizes acid in the stomach.

What are the common side effects of Oxramet IR 5/1000mg Tablet 14's?Arrow

Common side effects of Oxramet IR 5/1000mg Tablet 14's include nausea, vomiting, diarrhea, and abdominal pain.

Is Oxramet IR 5/1000mg Tablet 14's safe for patients with kidney problems?Arrow

Oxramet IR 5/1000mg Tablet 14's is not recommended in patients with kidney problems.

Is Oxramet IR 5/1000mg Tablet 14's safe during pregnancy?Arrow

Oxramet IR 5/1000mg Tablet 14's is not recommended during pregnancy.

Is Oxramet IR 5/1000mg Tablet 14's safe for breastfeeding mothers?Arrow

Oxramet IR 5/1000mg Tablet 14's is not recommended in breastfeeding mothers.

How to store Oxramet IR 5/1000mg Tablet 14's?Arrow

Store Oxramet IR 5/1000mg Tablet 14's at room temperature, away from direct sunlight and heat.

What happens if I miss a dose of Oxramet IR 5/1000mg Tablet 14's?Arrow

If you miss a dose of Oxramet IR 5/1000mg Tablet 14's, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.

Can I drink alcohol with Oxramet IR 5/1000mg Tablet 14's?Arrow

It is not recommended to drink alcohol with Oxramet IR 5/1000mg Tablet 14's, as it can increase the risk of side effects.

What are other brands of Metformin?Arrow

Some other brands of Metformin include Glucophage, Formet, and Riomet.

Does Oxramet IR 5/1000mg Tablet 14's cause weight gain?Arrow

Oxramet IR 5/1000mg Tablet 14's is not likely to cause weight gain. In fact, some people may experience weight loss with it.

What should I tell my doctor before starting Oxramet IR 5/1000mg Tablet 14's?Arrow

Before starting Oxramet IR 5/1000mg Tablet 14's, tell your doctor about all your medical conditions, allergies, and all the medications you are taking.

Can Oxramet IR 5/1000mg Tablet 14's interact with other medications?Arrow

Yes, Oxramet IR 5/1000mg Tablet 14's can interact with certain other medications. Tell your doctor about all the medications you are taking.

How long should I take Oxramet IR 5/1000mg Tablet 14's?Arrow

Follow your doctor's instructions on how long you should take Oxramet IR 5/1000mg Tablet 14's.

What is the composition of Oxramet Ir 5/1000MG Tablet 14's?Arrow

Oxramet Ir 5/1000MG Tablet 14's contains Dapagliflozin 5 MG + Metformin Hydrochloride 1000 MG Sustained Release. It is a SGLT2 inhibitor; and biguanide antidiabetic.

What are the side effects of Oxramet Ir 5/1000MG Tablet 14's?Arrow

Commonly reported side effects of Oxramet Ir 5/1000MG Tablet 14's include genital fungal infections, urinary tract infections, increased urination, thirst, dehydration; and diarrhoea, nausea, abdominal discomfort, metallic taste, loss of appetite — often improve with time or when taken with food. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Oxramet Ir 5/1000MG Tablet 14's?Arrow

Oxramet Ir 5/1000MG Tablet 14's is listed at Rs. 195.24 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Oxramet Ir 5/1000MG Tablet 14's?Arrow

Risk of euglycaemic diabetic ketoacidosis — ketones may be raised with near-normal glucose; seek care for nausea, vomiting or abdominal pain; and Rare but serious risk of lactic acidosis, particularly with kidney impairment, dehydration, acute illness or excess alcohol. Tell your doctor about all other medicines you take before starting Oxramet Ir 5/1000MG Tablet 14's.

What is the correct dosage of Oxramet Ir 5/1000MG Tablet 14's?Arrow

The dose of Oxramet Ir 5/1000MG Tablet 14's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Oxramet Ir 5/1000MG Tablet 14's?Arrow

A generic medicine is one with the same active composition as the branded product — for Oxramet Ir 5/1000MG Tablet 14's that is Dapagliflozin 5 MG + Metformin Hydrochloride 1000 MG Sustained Release. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Oxramet Ir 5/1000MG Tablet 14's.

Is Oxramet Ir 5/1000MG Tablet 14's a prescription medicine?Arrow

Yes. Oxramet Ir 5/1000MG Tablet 14's requires a valid doctor's prescription.

Who is the manufacturer of Oxramet Ir 5/1000MG Tablet 14's?Arrow

Oxramet Ir 5/1000MG Tablet 14's is manufactured by Sun Pharmaceutical Industries Ltd.

What is the dosage form of Oxramet Ir 5/1000MG Tablet 14's?Arrow

Oxramet Ir 5/1000MG Tablet 14's is supplied as a tablet and is taken by the oral route.

What are the benefits of Oxramet Ir 5/1000MG Tablet 14's?Arrow

Oxramet Ir 5/1000MG Tablet 14's contains Dapagliflozin 5 MG + Metformin Hydrochloride 1000 MG Sustained Release. It is used for type 2 diabetes mellitus; also used in heart failure and chronic kidney disease in selected patients; and first-line management of type 2 diabetes mellitus, usually alongside diet and exercise. The benefit you get depends on the condition your doctor prescribed Oxramet Ir 5/1000MG Tablet 14's for.

Is Oxramet Ir 5/1000MG Tablet 14's safe to take daily?Arrow

Whether Oxramet Ir 5/1000MG Tablet 14's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Oxramet Ir 5/1000MG Tablet 14's on your own.

When should Oxramet Ir 5/1000MG Tablet 14's be taken — morning or night?Arrow

The timing of Oxramet Ir 5/1000MG Tablet 14's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Oxramet Ir 5/1000MG Tablet 14's without a doctor's consultation?Arrow

No. Oxramet Ir 5/1000MG Tablet 14's is a prescription medicine and should only be taken on a doctor's advice.

Can Oxramet Ir 5/1000MG Tablet 14's be taken during pregnancy or breastfeeding?Arrow

Do not take Oxramet Ir 5/1000MG Tablet 14's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

Can I drink alcohol while taking Oxramet Ir 5/1000MG Tablet 14's?Arrow

Check with your doctor before drinking alcohol while taking Oxramet Ir 5/1000MG Tablet 14's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.

How should Oxramet Ir 5/1000MG Tablet 14's be stored?Arrow

Store Oxramet Ir 5/1000MG Tablet 14's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

Book Icon

FDA - XIGDUO XR (metformin hydrochloride and dapagliflozin) extended-release tablets - Prescribing Information. This document may contain relevant information on the individual components (metformin) and their related studies.

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DrugBank - Metformin. Provides detailed information on Metformin, including its mechanism of action, pharmacokinetics, and interactions.

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PubMed Central. A free archive of biomedical and life sciences literature. Search for 'Metformin' and 'extended release' for relevant research articles.

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European Medicines Agency (EMA). Search for information on Metformin-containing medications for regulatory information and scientific assessments.

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RxList - XIGDUO XR. Provides information on a drug containing both metformin and dapagliflozin, which can offer insights into the behavior and interactions of metformin.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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