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XIGDUO IR 5/1000MG TABLET 14'S

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XIGDUO IR 5/1000MG TABLET 14'S

By ASTRAZENECA PHARMA INDIA LIMITED

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397

₹337.45

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About XIGDUO IR 5/1000MG TABLET 14'S

  • XIGDUO IR 5/1000mg Tablet is a combination medicine used to treat type 2 diabetes mellitus. It combines two active ingredients: dapagliflozin and metformin hydrochloride. This medication is designed to help control blood sugar levels in adults with type 2 diabetes, especially when diet and exercise alone are not enough.
  • Dapagliflozin belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine, effectively lowering blood sugar levels. Additionally, dapagliflozin can provide benefits such as weight loss and blood pressure reduction.
  • Metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity. It helps to lower blood sugar levels by reducing the amount of glucose released by the liver and improving the body's ability to use insulin. Metformin is a commonly prescribed drug for type 2 diabetes and is known for its effectiveness and safety.
  • XIGDUO IR 5/1000mg is typically taken orally once or twice daily with meals to minimize gastrointestinal side effects. The dosage is usually adjusted based on individual needs and as directed by a healthcare provider. It is crucial to follow the prescribed dosage and schedule to achieve optimal blood sugar control.
  • This medicine helps improve glycemic control, reduce the risk of cardiovascular events, and enhance overall well-being for individuals managing type 2 diabetes. Regular monitoring of blood sugar levels and kidney function is recommended while taking XIGDUO IR 5/1000mg. Patients should also maintain a healthy lifestyle, including a balanced diet and regular exercise, to maximize the benefits of this medication.

Uses of XIGDUO IR 5/1000MG TABLET 14'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Used in conjunction with diet and exercise
  • Improving blood sugar control
  • Management of type 2 diabetes in adults

How XIGDUO IR 5/1000MG TABLET 14'S Works

  • XIGDUO IR 5/1000MG TABLET 14'S is a combination medicine designed to help manage blood sugar levels in adults with type 2 diabetes. It contains two active ingredients: dapagliflozin and metformin hydrochloride. Each component works through different mechanisms to improve glycemic control.
  • Dapagliflozin belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys that helps reabsorb glucose back into the bloodstream. Dapagliflozin works by blocking SGLT2, which reduces the reabsorption of glucose and increases glucose excretion in the urine. This process lowers blood sugar levels. By removing excess glucose through urine, dapagliflozin also contributes to weight loss and may offer cardiovascular benefits.
  • Metformin hydrochloride is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. In the liver, metformin inhibits gluconeogenesis, the process by which the liver produces glucose from non-carbohydrate sources. It also slows down the absorption of glucose from the intestines. Furthermore, metformin increases insulin sensitivity in peripheral tissues, allowing cells to utilize glucose more effectively. Metformin does not typically cause hypoglycemia (low blood sugar) when used alone because it does not stimulate insulin secretion.
  • The combination of dapagliflozin and metformin in XIGDUO IR 5/1000MG TABLET 14'S provides a dual-action approach to managing blood sugar. Dapagliflozin helps remove excess glucose from the body, while metformin reduces glucose production and improves insulin sensitivity. Together, they offer a more comprehensive approach to glycemic control than either medication alone. This combination helps to lower both fasting and post-meal blood sugar levels effectively.
  • It is crucial to use XIGDUO IR 5/1000MG TABLET 14'S as prescribed by your healthcare provider. They will determine the appropriate dosage and monitor your blood sugar levels to ensure the medication is working effectively. Regular monitoring and adherence to a healthy diet and exercise plan are essential for optimal diabetes management while taking this medication.

Side Effects of XIGDUO IR 5/1000MG TABLET 14'SArrow

The following side effects may occur while taking XIGDUO IR 5/1000MG TABLET: **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Headache * Weakness * Hypoglycemia (low blood sugar), especially when used with other diabetes medications * Upper respiratory tract infection **Uncommon Side Effects:** * Skin rash or itching * Vitamin B12 deficiency * Lactic acidosis (rare but serious). Symptoms include feeling very weak or tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat. * Joint pain **Rare Side Effects:** * Pancreatitis (inflammation of the pancreas) * Liver problems **Important Considerations:** * This is not a complete list of side effects. Tell your doctor if you experience any unusual or bothersome symptoms. * Seek immediate medical attention if you experience symptoms of a serious side effect, such as lactic acidosis or a severe allergic reaction.

Safety Advice for XIGDUO IR 5/1000MG TABLET 14'SArrow

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Allergies

Allergies

Do not use XIGDUO IR 5/1000MG TABLET 14'S if you are allergic to it.

Dosage of XIGDUO IR 5/1000MG TABLET 14'SArrow

  • The recommended dosage of XIGDUO IR 5/1000MG TABLET 14'S varies depending on individual patient needs and tolerability, but it is crucial to adhere strictly to your physician's instructions. The typical starting dose is one tablet taken twice daily, preferably with meals to minimize gastrointestinal discomfort. The maximum recommended daily dose is 10 mg of dapagliflozin and 2000 mg of metformin hydrochloride immediate-release.
  • Your doctor may adjust your dosage gradually based on your blood glucose levels and kidney function. It's important to monitor your blood sugar regularly as directed by your healthcare provider to assess how well the medication is working and to guide dosage adjustments. Do not exceed the prescribed dose, and do not take more than the maximum daily dose. Taking XIGDUO IR 5/1000MG TABLET 14'S at the same times each day will help you remember to take it.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. If you have kidney problems, your doctor might adjust the dosage or not prescribe this medication. It's also important to maintain a healthy diet and exercise regularly while taking this medication to achieve the best results. Always inform your doctor about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with XIGDUO IR 5/1000MG TABLET 14'S. Take 'XIGDUO IR 5/1000MG TABLET 14'S' only as per the prescription by your physician only

What if I miss my dose of XIGDUO IR 5/1000MG TABLET 14'S?Arrow

  • If you miss a dose of XIGDUO IR 5/1000mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.

How to store XIGDUO IR 5/1000MG TABLET 14'S?Arrow

  • Keep XIGDUO IR 5/1000MG TAB 1X14 away from the reach of children and pets.
  • Store XIGDUO IR 5/1000MG TAB 1X14 at room temperature.

Benefits of XIGDUO IR 5/1000MG TABLET 14'SArrow

  • XIGDUO IR 5/1000MG TABLET 14'S is a combination medicine containing dapagliflozin and metformin, designed to manage blood sugar levels in adults with type 2 diabetes mellitus. It works through complementary mechanisms to achieve comprehensive glycemic control. Dapagliflozin belongs to a class of drugs called SGLT2 inhibitors, while metformin is a biguanide.
  • One of the primary benefits of XIGDUO IR is its dual action in lowering blood glucose. Metformin reduces glucose production in the liver and improves insulin sensitivity, enabling cells to use insulin more effectively. Dapagliflozin works in the kidneys by preventing the reabsorption of glucose, leading to excess glucose being excreted through urine. This combined action results in significant reduction of HbA1c levels, a key marker of long-term blood sugar control.
  • Beyond glycemic control, XIGDUO IR offers cardiovascular benefits. Dapagliflozin has been shown to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors. This makes XIGDUO IR a beneficial choice for individuals concerned about heart health alongside diabetes management.
  • Weight management is another advantage associated with XIGDUO IR. Dapagliflozin promotes glucose excretion, which results in calorie loss and subsequent weight reduction. Metformin can also contribute to weight management by reducing appetite and improving metabolic processes. This can be particularly beneficial for overweight or obese individuals with type 2 diabetes.
  • XIGDUO IR can improve blood pressure control. Studies have indicated that dapagliflozin can lead to a modest reduction in systolic blood pressure. This is an added advantage for individuals with both diabetes and hypertension, contributing to overall cardiovascular health.
  • The convenience of a once- or twice-daily oral medication enhances adherence to treatment. XIGDUO IR simplifies the treatment regimen, making it easier for patients to manage their condition effectively. This can improve overall health outcomes by ensuring consistent medication intake.
  • XIGDUO IR is generally well-tolerated. While side effects can occur, they are typically mild and manageable. Common side effects include genital infections (due to increased glucose in the urine), urinary tract infections, and gastrointestinal symptoms like nausea or diarrhea, which are more associated with metformin. However, the benefits of improved glycemic control and cardiovascular protection often outweigh these potential side effects.
  • By effectively managing blood sugar levels, XIGDUO IR helps prevent or delay the onset of long-term complications associated with diabetes. These complications include kidney damage (nephropathy), nerve damage (neuropathy), eye damage (retinopathy), and cardiovascular problems. By reducing the risk of these complications, XIGDUO IR contributes to improved long-term health and quality of life.
  • XIGDUO IR can be used in combination with other diabetes medications, such as sulfonylureas or insulin, to achieve optimal glycemic control. This allows for individualized treatment plans tailored to the specific needs of each patient. However, it is important to consult with a healthcare professional to determine the most appropriate combination therapy.
  • In summary, XIGDUO IR 5/1000MG TABLET 14'S offers a multifaceted approach to managing type 2 diabetes. Its benefits include effective blood sugar control, cardiovascular protection, weight management, improved blood pressure, convenient dosing, and the potential to prevent long-term diabetes complications. These advantages make XIGDUO IR a valuable treatment option for individuals seeking comprehensive diabetes care. As always, consult your doctor for personalized medical advice.

How to use XIGDUO IR 5/1000MG TABLET 14'SArrow

  • XIGDUO IR 5/1000MG TABLET 14'S is designed for oral administration and should be taken exactly as prescribed by your healthcare provider. The usual starting dose depends on your current medications and individual needs, so following your doctor's instructions is crucial. Generally, it is taken twice daily with meals to help reduce gastrointestinal side effects and improve absorption. Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
  • Consistency is key to the effectiveness of XIGDUO IR 5/1000MG TABLET 14'S. Try to take it at the same times each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.
  • While taking XIGDUO IR 5/1000MG TABLET 14'S, it's important to adhere to your diet and exercise plan as recommended by your doctor or diabetes educator. This medication works best when combined with a healthy lifestyle. Regularly monitor your blood sugar levels as directed by your healthcare provider and report any unusual readings or symptoms promptly. It is also advisable to inform all your healthcare providers that you are taking this medication before any surgery or medical procedures. Store XIGDUO IR 5/1000MG TABLET 14'S at room temperature, away from moisture and heat, and keep it out of reach of children.
  • It's important to note that XIGDUO IR 5/1000MG TABLET 14'S is a prescription medication, and you should not share it with anyone, even if they have similar symptoms. Periodic kidney function tests and vitamin B12 level checks might be recommended while you are on this medication. If you experience any side effects, such as nausea, vomiting, diarrhea, or signs of lactic acidosis (such as unusual tiredness, muscle pain, or difficulty breathing), contact your doctor immediately.

Quick Tips for XIGDUO IR 5/1000MG TABLET 14'SArrow

  • Take XIGDUO IR 5/1000MG exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen is crucial for effective blood sugar control and minimizing potential side effects. Skipping doses can lead to fluctuations in blood sugar levels, making it harder to manage your diabetes.
  • Administer XIGDUO IR 5/1000MG with meals to help reduce gastrointestinal side effects like nausea and diarrhea. Taking it on an empty stomach can increase the likelihood of experiencing these discomforts. Food also aids in the absorption and utilization of the medication, contributing to more stable blood sugar levels throughout the day. Ensure you have a consistent meal schedule to optimize the medication's effectiveness.
  • Regularly monitor your blood sugar levels as directed by your doctor while taking XIGDUO IR 5/1000MG. Keeping a log of your readings can help you and your healthcare provider assess how well the medication is working and make necessary adjustments to your treatment plan. Understanding how different foods, activities, and stressors affect your blood sugar can empower you to manage your diabetes more effectively.
  • Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function and helps your body process the medication more efficiently. Dehydration can also affect blood sugar levels, so maintaining proper hydration is essential for overall diabetes management. Aim for at least eight glasses of water per day, unless your doctor advises otherwise.
  • Be aware of the symptoms of low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia). XIGDUO IR 5/1000MG can potentially cause both conditions. Hypoglycemia symptoms include shakiness, sweating, dizziness, and confusion, while hyperglycemia symptoms include increased thirst, frequent urination, and blurred vision. Knowing these symptoms and how to respond to them is crucial for preventing complications and maintaining your health. Always carry a source of fast-acting sugar, such as glucose tablets or juice, in case of hypoglycemia.

Food Interactions with XIGDUO IR 5/1000MG TABLET 14'SArrow

  • XIGDUO IR 5/1000MG TABLET 14'S should be taken with food to decrease the chances of stomach upset.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis (a serious metabolic condition).
  • There are no specific food restrictions while taking XIGDUO IR 5/1000MG TABLET 14'S, but maintaining a balanced diet is always recommended for overall health and diabetes management. Consult your doctor or dietician for personalized dietary advice.

FAQs

What is XIGDUO IR 5/1000mg Tablet used for?Arrow

XIGDUO IR 5/1000mg Tablet is used to treat type 2 diabetes mellitus in adults, improving blood sugar control when diet and exercise are not sufficient.

How should I take XIGDUO IR 5/1000mg Tablet?Arrow

Take XIGDUO IR 5/1000mg Tablet as prescribed by your doctor, usually with meals to reduce stomach upset. Swallow the tablet whole with a glass of water.

What are the common side effects of XIGDUO IR 5/1000mg Tablet?Arrow

Common side effects may include nausea, vomiting, diarrhea, stomach pain, and headache. Consult your doctor if these persist or worsen.

Can I take XIGDUO IR 5/1000mg Tablet if I have kidney problems?Arrow

XIGDUO IR 5/1000mg Tablet may not be suitable for people with severe kidney problems. Consult your doctor to determine if it is safe for you.

What should I do if I miss a dose of XIGDUO IR 5/1000mg Tablet?Arrow

If you miss a dose, take it as soon as you remember. However, if it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can XIGDUO IR 5/1000mg Tablet be used during pregnancy or breastfeeding?Arrow

Consult your doctor before using XIGDUO IR 5/1000mg Tablet during pregnancy or breastfeeding, as it may not be safe for the baby.

Does XIGDUO IR 5/1000mg Tablet interact with other medications?Arrow

XIGDUO IR 5/1000mg Tablet can interact with certain medications, including diuretics and insulin. Inform your doctor about all medications you are taking.

What should I avoid while taking XIGDUO IR 5/1000mg Tablet?Arrow

Avoid excessive alcohol consumption while taking XIGDUO IR 5/1000mg Tablet, as it can increase the risk of side effects.

How does XIGDUO IR 5/1000mg Tablet work?Arrow

XIGDUO IR 5/1000mg Tablet contains two medicines: dapagliflozin and metformin. Dapagliflozin removes excess sugar from your body through urine, while metformin reduces glucose production in the liver and improves insulin sensitivity.

What are the symptoms of an overdose of XIGDUO IR 5/1000mg Tablet?Arrow

Symptoms of an overdose may include nausea, vomiting, stomach pain, diarrhea, and potentially lactic acidosis. Seek immediate medical attention if you suspect an overdose.

How should I store XIGDUO IR 5/1000mg Tablet?Arrow

Store XIGDUO IR 5/1000mg Tablet at room temperature, away from moisture and heat. Keep it out of reach of children.

Can XIGDUO IR 5/1000mg Tablet cause hypoglycemia?Arrow

XIGDUO IR 5/1000mg Tablet can cause hypoglycemia, especially when taken with other diabetes medications or insulin. Be aware of the symptoms of low blood sugar and consult your doctor.

Are there any specific dietary recommendations while taking XIGDUO IR 5/1000mg Tablet?Arrow

Follow a balanced diet as recommended by your doctor or dietitian. Consistent carbohydrate intake is important to prevent fluctuations in blood sugar levels.

What should I do if I experience severe side effects while taking XIGDUO IR 5/1000mg Tablet?Arrow

If you experience severe side effects such as difficulty breathing, severe abdominal pain, or signs of an allergic reaction, seek immediate medical attention.

Is XIGDUO IR 5/1000mg Tablet the same as other diabetes medications with metformin?Arrow

XIGDUO IR 5/1000mg Tablet contains both dapagliflozin and metformin. Other medications may contain only metformin or metformin in combination with a different drug. Consult your doctor to understand the best treatment option for you.

References

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (n.d.). Retrieved from https://www.ema.europa.eu/en/documents/product-information/xigduo-epar-product-information_en.pdf

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (n.d.). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205649s008lbl.pdf

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XIGDUO IR 5/1000MG TABLET 14'S

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₹337.45

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