OXRAMET IR 5MG/500MG TABLET 14'S
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OXRAMET IR 5MG/500MG TABLET 14'S
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OXRAMET IR 5MG/500MG TABLET 14'S

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OXRAMET IR 5MG/500MG TABLET 14'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

117

₹99.45

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10

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About OXRAMET IR 5MG/500MG TABLET 14'S

  • OXRAMET IR 5MG/500MG TABLET is a combination medicine specifically formulated to manage type 2 diabetes mellitus. It combines two powerful active ingredients: Oxagliptin (5mg) and Metformin Hydrochloride (500mg). This dual-action approach helps patients achieve better glycemic control compared to using either medication alone. It is usually prescribed when diet and exercise alone are not sufficient to manage blood sugar levels.
  • Oxagliptin belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amount of incretin hormones released by the gut after a meal. These hormones stimulate the release of insulin from the pancreas and reduce the production of glucagon, a hormone that raises blood sugar levels. By enhancing insulin secretion and suppressing glucagon, oxagliptin helps lower post-meal blood sugar spikes.
  • Metformin Hydrochloride, on the other hand, is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It also slows down the absorption of glucose from the intestines. Metformin is a well-established medication for type 2 diabetes and has been shown to have beneficial effects on cardiovascular health.
  • The combination of Oxagliptin and Metformin in OXRAMET IR offers a synergistic effect, addressing multiple pathways involved in blood sugar regulation. This can lead to improved HbA1c levels, a measure of long-term blood sugar control. OXRAMET IR is typically taken once or twice daily with meals, as directed by your healthcare provider. It's essential to follow your doctor's instructions carefully and maintain a healthy lifestyle, including regular exercise and a balanced diet, to maximize the benefits of this medication. Always consult with your physician or pharmacist for any questions or concerns regarding your medication.
  • OXRAMET IR is available in a pack of 14 tablets for ease of use and convenience.

Uses of OXRAMET IR 5MG/500MG TABLET 14'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Use in Polycystic Ovary Syndrome (PCOS) (off-label)
  • Helps in blood sugar control
  • Use in adults with type 2 diabetes
  • Used in combination with diet and exercise

How OXRAMET IR 5MG/500MG TABLET 14'S Works

  • OXRAMET IR 5MG/500MG TABLET is a combination medication designed to manage type 2 diabetes effectively. It combines two active ingredients: Metformin and a Sulfonylurea. These work through different mechanisms to control blood sugar levels, offering a synergistic effect that helps patients achieve better glycemic control than with either medication alone.
  • Metformin, a biguanide, is the cornerstone of treatment for many individuals with type 2 diabetes. Its primary action is to decrease glucose production in the liver. The liver is a key player in glucose metabolism, and in individuals with diabetes, it often produces excessive amounts of glucose, contributing to hyperglycemia (high blood sugar). Metformin helps to suppress this overproduction, reducing the amount of glucose released into the bloodstream. Moreover, Metformin enhances insulin sensitivity in peripheral tissues, such as muscles. This means that the body becomes more responsive to the insulin that is available, allowing glucose to be taken up more efficiently by the cells for energy. Importantly, Metformin does not typically cause hypoglycemia (low blood sugar) when used alone because it does not stimulate insulin secretion directly.
  • The other component of OXRAMET IR is a Sulfonylurea. Sulfonylureas work by stimulating the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the bloodstream into cells, where it can be used for energy. By increasing insulin secretion, sulfonylureas help lower blood sugar levels. However, because sulfonylureas directly stimulate insulin release, there is a risk of hypoglycemia, especially if meals are skipped or if the dose is too high. Common side effects associated with sulfonylureas include weight gain and, as mentioned, hypoglycemia.
  • When Metformin and a Sulfonylurea are combined in OXRAMET IR, they address different aspects of glucose control. Metformin reduces glucose production in the liver and enhances insulin sensitivity, while the Sulfonylurea increases insulin secretion from the pancreas. This dual action can lead to more effective blood sugar management than either drug alone. However, it's crucial to be aware of the potential for hypoglycemia and to follow your healthcare provider's instructions carefully regarding diet, exercise, and medication timing.
  • In summary, OXRAMET IR works by targeting multiple pathways involved in glucose metabolism. It reduces hepatic glucose production, enhances insulin sensitivity, and increases insulin secretion. This comprehensive approach helps to lower blood sugar levels and improve overall glycemic control in individuals with type 2 diabetes. Always use this medication under the guidance of a healthcare professional to ensure safe and effective treatment.

Side Effects of OXRAMET IR 5MG/500MG TABLET 14'SArrow

Possible side effects of OXRAMET IR 5MG/500MG Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), skin rash, itching, and in rare cases, lactic acidosis. Other potential side effects are headache, dizziness, constipation, upper respiratory tract infection and edema. Contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for OXRAMET IR 5MG/500MG TABLET 14'SArrow

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Allergies

Allergies

Do not use Oxramet IR 5MG/500MG Tablet 14'S if you are allergic to it or any of its ingredients.

Dosage of OXRAMET IR 5MG/500MG TABLET 14'SArrow

  • The recommended dosage of OXRAMET IR 5MG/500MG TABLET 14'S varies depending on individual patient needs and response to treatment. It is crucial to adhere strictly to your doctor's instructions regarding dosage and timing. The usual starting dose is one tablet, two or three times daily, administered orally. This is to be taken with meals to minimize gastrointestinal discomfort.
  • Your physician may gradually increase the dosage based on your blood glucose levels and tolerance. The maximum recommended daily dose of metformin (present in OXRAMET IR 5MG/500MG TABLET 14'S) is typically 2550 mg, usually divided into multiple doses. Rosiglitazone, the other active ingredient, also has a dosage limit that your doctor will consider.
  • It is important to swallow the tablet whole with a glass of water and not to crush, chew, or break it. Consistent timing of doses is crucial for maintaining stable blood sugar levels. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.
  • Regular monitoring of blood glucose levels is essential while taking OXRAMET IR 5MG/500MG TABLET 14'S. Your doctor will also monitor your kidney and liver function periodically, as well as other relevant parameters. Dosage adjustments may be necessary based on these monitoring results.
  • Take 'OXRAMET IR 5MG/500MG TABLET 14'S' only as per the prescription by your physician only.

What if I miss my dose of OXRAMET IR 5MG/500MG TABLET 14'S?Arrow

  • If you miss a dose of OXRAMET IR 5MG/500MG TABLET 14'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store OXRAMET IR 5MG/500MG TABLET 14'S?Arrow

  • Keep OXRAMET IR 5/500MG TAB 1X14 away from the reach of children and pets.
  • Store OXRAMET IR 5/500MG TAB 1X14 at room temperature.

Benefits of OXRAMET IR 5MG/500MG TABLET 14'SArrow

  • OXRAMET IR 5MG/500MG TABLET 14'S is a combination medicine used to treat type 2 diabetes mellitus. It effectively controls high blood sugar levels by improving the body's sensitivity to insulin and reducing the amount of glucose produced by the liver. This dual action helps maintain stable blood sugar levels throughout the day, reducing the risk of hyperglycemia and its associated complications.
  • One of the primary benefits of OXRAMET IR is its ability to enhance insulin sensitivity. Insulin is a hormone that helps glucose enter cells to be used for energy. In type 2 diabetes, cells become resistant to insulin, leading to elevated blood sugar levels. OXRAMET IR helps overcome this resistance, allowing insulin to function more effectively and lower blood sugar.
  • OXRAMET IR also reduces glucose production in the liver. The liver can sometimes produce excessive amounts of glucose, especially during periods of fasting or between meals. By inhibiting this process, OXRAMET IR helps prevent blood sugar spikes and contributes to overall glycemic control.
  • Taking OXRAMET IR as prescribed by your doctor can lead to several significant health benefits. Effective blood sugar control reduces the risk of developing serious long-term complications of diabetes, such as kidney disease (nephropathy), nerve damage (neuropathy), eye damage (retinopathy), and cardiovascular problems.
  • Managing blood sugar levels with OXRAMET IR can also improve energy levels and reduce fatigue often associated with poorly controlled diabetes. When blood sugar is stable, the body can utilize glucose more efficiently, providing a consistent source of energy.
  • OXRAMET IR can also aid in weight management. While not specifically a weight-loss medication, by improving insulin sensitivity and regulating blood sugar, it can help reduce cravings and prevent the storage of excess glucose as fat. This can be a beneficial side effect for individuals with type 2 diabetes who are also trying to manage their weight.
  • Furthermore, OXRAMET IR contributes to better overall metabolic health. By addressing both insulin resistance and excessive glucose production, it helps restore a more balanced metabolic state, reducing the risk of other metabolic disorders associated with diabetes.
  • The convenience of a combination tablet like OXRAMET IR also improves adherence to treatment. Instead of taking multiple pills, patients can manage their condition with a single tablet, simplifying their medication regimen and increasing the likelihood of consistent use.
  • OXRAMET IR, when combined with lifestyle modifications such as a healthy diet and regular exercise, can significantly improve the quality of life for individuals with type 2 diabetes. It empowers patients to take control of their health and proactively manage their condition, leading to better long-term outcomes.

How to use OXRAMET IR 5MG/500MG TABLET 14'SArrow

  • OXRAMET IR 5MG/500MG TABLET 14'S should be taken orally, preferably with meals to minimize gastrointestinal side effects. Always follow your doctor's instructions regarding dosage and timing. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water.
  • The usual starting dose is one tablet once or twice daily, but your doctor may adjust the dosage based on your blood glucose levels and individual response to the medication. It is crucial to take OXRAMET IR at the same time(s) each day to maintain consistent blood sugar control. Missing doses can lead to fluctuations in blood sugar levels, potentially causing hyperglycemia.
  • Before starting OXRAMET IR, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart disease, or any allergies. Also, disclose all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, as they may interact with OXRAMET IR. Alcohol consumption should be avoided or limited while taking this medication, as it can increase the risk of side effects and interfere with blood sugar control.
  • Continue taking OXRAMET IR even if you feel well. It is essential for long-term blood sugar management. Do not stop taking it without consulting your doctor. Regular monitoring of blood glucose levels is necessary while on OXRAMET IR. Your doctor may also recommend periodic blood tests to assess kidney function and vitamin B12 levels.
  • If you experience any unusual side effects, such as severe nausea, vomiting, diarrhea, abdominal pain, or signs of lactic acidosis (e.g., rapid breathing, muscle cramps, unusual fatigue), seek immediate medical attention. Store OXRAMET IR at room temperature, away from moisture and heat, and keep it out of reach of children.

Quick Tips for OXRAMET IR 5MG/500MG TABLET 14'SArrow

  • Take OXRAMET IR 5MG/500MG TABLET 14'S as prescribed by your doctor. Adhere strictly to the dosage and timing instructions provided by your healthcare provider to maintain consistent blood sugar levels. Avoid self-adjusting the dose or discontinuing the medication without consulting your doctor.
  • Administer OXRAMET IR 5MG/500MG TABLET 14'S with or immediately after meals to minimize potential gastrointestinal discomfort. This can help reduce the risk of nausea, stomach upset, or diarrhea, common side effects associated with metformin. Consistent timing with meals optimizes the drug's absorption and effectiveness.
  • Monitor your blood sugar levels regularly as advised by your doctor while taking OXRAMET IR 5MG/500MG TABLET 14'S. Keeping a log of your blood glucose readings can help you and your healthcare provider assess how well the medication is working and make necessary adjustments to your treatment plan. Regular monitoring also aids in detecting and managing hypoglycemia or hyperglycemia.
  • Stay hydrated by drinking plenty of water throughout the day when taking OXRAMET IR 5MG/500MG TABLET 14'S. Adequate hydration supports kidney function and helps the body eliminate excess glucose through urine. Dehydration can exacerbate certain side effects and impact the drug's effectiveness.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting OXRAMET IR 5MG/500MG TABLET 14'S. Drug interactions can affect how OXRAMET IR works or increase the risk of side effects. This includes over-the-counter medications, vitamins, and herbal remedies. Always provide a complete and accurate medical history to your healthcare provider.

Food Interactions with OXRAMET IR 5MG/500MG TABLET 14'SArrow

  • OXRAMET IR 5MG/500MG TABLET 14'S is generally recommended to be taken with food to minimize gastrointestinal side effects such as nausea, vomiting, or diarrhea. High-fiber foods may slightly delay the absorption of metformin, one of the active ingredients. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a rare but serious side effect.

FAQs

What is the use of Oxramet IR 5mg/500mg Tablet?Arrow

Oxramet IR 5mg/500mg Tablet is used to treat type 2 diabetes mellitus, especially when diet and exercise alone are not sufficient to control blood sugar levels.

How does Oxramet IR 5mg/500mg Tablet work?Arrow

Oxramet IR 5mg/500mg Tablet is a combination of two medicines: Metformin and Glimepiride. Metformin works by decreasing glucose production in the liver and improving insulin sensitivity, while Glimepiride increases the release of insulin from the pancreas.

What are the common side effects of Oxramet IR 5mg/500mg Tablet?Arrow

Common side effects of Oxramet IR 5mg/500mg Tablet include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is Oxramet IR 5mg/500mg Tablet safe for patients with kidney disease?Arrow

Oxramet IR 5mg/500mg Tablet should be used with caution in patients with kidney disease as it may increase the risk of lactic acidosis. Dosage adjustments may be necessary.

Should Oxramet IR 5mg/500mg Tablet be taken with food?Arrow

It is recommended to take Oxramet IR 5mg/500mg Tablet with food to minimize stomach upset.

What happens if I miss a dose of Oxramet IR 5mg/500mg Tablet?Arrow

If you miss a dose of Oxramet IR 5mg/500mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Is Oxramet IR 5mg/500mg Tablet safe during pregnancy?Arrow

Oxramet IR 5mg/500mg Tablet is not recommended during pregnancy. Insulin is generally preferred during pregnancy.

Can Oxramet IR 5mg/500mg Tablet be taken with other medications?Arrow

Oxramet IR 5mg/500mg Tablet can interact with other medications. Inform your doctor about all the medications you are taking to avoid any potential interactions.

How to store Oxramet IR 5mg/500mg Tablet?Arrow

Store Oxramet IR 5mg/500mg Tablet at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Does Oxramet IR 5mg/500mg Tablet cause weight gain?Arrow

Oxramet IR 5mg/500mg Tablet, particularly the Glimepiride component, may cause weight gain in some patients. It's important to be mindful of your diet and exercise habits.

Can I drink alcohol while taking Oxramet IR 5mg/500mg Tablet?Arrow

Alcohol should be avoided while taking Oxramet IR 5mg/500mg Tablet as it can increase the risk of hypoglycemia (low blood sugar).

Can Oxramet IR 5mg/500mg Tablet be given to children?Arrow

Oxramet IR 5mg/500mg Tablet is not recommended for use in children as its safety and efficacy have not been established in pediatric patients.

What happens if I overdose on Oxramet IR 5mg/500mg Tablet?Arrow

An overdose of Oxramet IR 5mg/500mg Tablet can lead to serious side effects such as hypoglycemia (low blood sugar) and lactic acidosis. Seek immediate medical attention.

Should I monitor my blood sugar levels while taking Oxramet IR 5mg/500mg Tablet?Arrow

Yes, it is important to monitor your blood sugar levels regularly while taking Oxramet IR 5mg/500mg Tablet to ensure the medication is effective and to avoid hypoglycemia.

Are other medications containing 'Glimepiride and Metformin' the same as Oxramet IR 5mg/500mg Tablet?Arrow

While they may contain the same active ingredients (Glimepiride and Metformin), formulations from different brands or manufacturers can vary. Always consult with your doctor or pharmacist to determine which is best for you.

References

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DrugBank: Metformin and Vildagliptin Combination

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FDA Drug Label: Metformin Hydrochloride and Vildagliptin Tablets

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European Medicines Agency (EMA): Eucreas (vildagliptin / metformin hydrochloride)

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National Center for Biotechnology Information (NCBI): Vildagliptin/metformin fixed-dose combination: a review of its use in the management of type 2 diabetes mellitus

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National Center for Biotechnology Information (NCBI): Efficacy of Vildagliptin/Metformin Combination Compared to Other Oral Antidiabetic Drugs in Type 2 Diabetes Mellitus

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ScienceDirect: Vildagliptin

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ScienceDirect: Metformin

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OXRAMET IR 5MG/500MG TABLET 14'S

OXRAMET IR 5MG/500MG TABLET 14'S

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₹99.45

15 % OFF

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