PEXOTRA 100MG INJECTION
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PEXOTRA 100MG INJECTION
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PEXOTRA 100MG INJECTION

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PEXOTRA 100MG INJECTION

By GLENMARK PHARMACEUTICALS LIMITED

MRP

1100

₹935

15 % OFF

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Product DetailsArrow

About PEXOTRA 100MG INJECTION

  • PEXOTRA 100MG INJECTION is an anticancer medication containing pemetrexed as its active ingredient. It belongs to a class of medications known as antifolate agents. This injection is primarily used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma, which are cancers affecting the lungs and chest lining. It can be administered as a standalone treatment or in combination with other anticancer drugs, such as cisplatin. To minimize potential side effects, your healthcare provider may also prescribe corticosteroids, folic acid, and vitamin B12 supplements during your treatment.
  • Before each infusion of PEXOTRA 100MG INJECTION, blood tests will be conducted to assess your kidney and liver function, as well as to ensure you have an adequate number of blood cells. It is crucial to inform your doctor about any pre-existing or past medical conditions, especially those related to kidney problems, heart disorders, or fluid accumulation in the lungs. Additionally, notify your doctor if you have recently undergone or are currently undergoing radiotherapy or have received any vaccinations.
  • It is essential to inform your doctor if you are planning to become pregnant or suspect you may be pregnant. Women should use effective contraception during treatment and for at least six months after the last dose of PEXOTRA 100MG INJECTION. Men are advised not to father a child during treatment and for up to three months afterward. Consulting your doctor about fertility concerns is highly recommended. This medication is generally not recommended for adolescents and children under the age of 18. The dosage and duration of treatment will be determined by your doctor based on your specific condition and response to the medication. Always follow your doctor's instructions carefully and report any unusual side effects promptly.
  • Furthermore, it's important to maintain adequate hydration during the treatment period, as this can help reduce the risk of kidney-related side effects. Your doctor may advise you to drink plenty of fluids. Avoid taking any other medications, including over-the-counter drugs and herbal supplements, without first consulting your doctor, as they may interact with PEXOTRA 100MG INJECTION. Regular check-ups and monitoring are crucial to assess your progress and manage any potential complications.

Uses of PEXOTRA 100MG INJECTION

  • Malignant pleural mesothelioma: This is a type of cancer that develops in the lining of the lungs.
  • Non-small cell lung carcinoma: This is the most common type of lung cancer and includes several subtypes.

Side Effects of PEXOTRA 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Common:

  • Blood infection
  • Severe allergic reaction
  • Breathlessness, intense chest pain or cough with bloody sputum
  • Reduced neutrophil granulocytes (white blood cells)
  • Kidney failure
  • Pharyngitis (a sore throat)
  • Abnormal liver function
  • Fatigue
  • Nausea, vomiting, diarrhea
  • Redness, swelling or sores in the mouth
  • Loss of appetite, sensation
  • Reduced hemoglobin level
  • Increased skin pigmentation
  • Watery and inflamed eyes, taste change
  • Fever
  • Muscle weakness
  • Dehydration
  • Constipation
  • Skin rash
  • Hair loss

Safety Advice for PEXOTRA 100MG INJECTIONArrow

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Pregnancy

UNSAFE

Do not take PEXOTRA 100MG INJECTION if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.

Dosage of PEXOTRA 100MG INJECTIONArrow

  • PEXOTRA 100MG INJECTION is administered directly into a vein through intravenous infusion. This method ensures the medication is delivered efficiently into your bloodstream. Because this is a specialized treatment, a qualified healthcare professional will administer the injection. Self-administration is strictly not recommended to avoid potential complications.
  • The precise dosage and frequency of PEXOTRA 100MG INJECTION administration will be determined by your physician. These factors are carefully tailored to your specific medical condition and individual needs. Each person's response to the medication can vary, so the dosage regimen is personalized for optimal effectiveness.
  • Your doctor will continuously monitor your progress and adjust the dosage as needed to achieve the best possible outcome. It's important to openly communicate with your healthcare provider about any concerns or side effects you may experience during the treatment. This collaborative approach ensures the safest and most effective use of PEXOTRA 100MG INJECTION.

How to store PEXOTRA 100MG INJECTION?Arrow

  • Keep PEXOTRA 100MG INJ away from the reach of children and pets.
  • Store PEXOTRA 100MG INJ at room temperature.

Benefits of PEXOTRA 100MG INJECTIONArrow

  • PEXOTRA 100MG INJECTION is a medication that works by disrupting the fundamental processes that cancer cells rely on to grow and spread. Specifically, it targets and inhibits enzymes crucial for folate metabolism. Folate is a type of B vitamin that cells need to synthesize DNA and divide. By blocking these enzymes, PEXOTRA 100MG INJECTION effectively halts the production of DNA, which is the genetic blueprint of cells. Without the ability to create new DNA, cancer cells cannot replicate properly.
  • This interference with DNA synthesis has a cascading effect, ultimately preventing cancer cells from undergoing cell division and proliferation. Essentially, the drug stops the cancer cells from making copies of themselves, slowing down the growth of the tumor and hindering its ability to spread to other parts of the body. This mechanism of action makes PEXOTRA 100MG INJECTION a valuable tool in cancer treatment, helping to control the disease and improve patient outcomes. The targeted approach aims to selectively affect cancer cells while minimizing damage to healthy cells, though some side effects can still occur.
  • Further elaborating, PEXOTRA 100MG INJECTION's impact on folate metabolism not only affects DNA synthesis but also disrupts the production of RNA and certain proteins essential for cell survival. This multi-pronged attack weakens the cancer cells and makes them more susceptible to other cancer treatments such as chemotherapy or radiation therapy. The overall goal is to provide a comprehensive approach to cancer management.

How to use PEXOTRA 100MG INJECTIONArrow

  • PEXOTRA 100MG INJECTION is administered as an intravenous infusion directly into a vein. Due to the specialized nature of this administration, it is crucial that a qualified healthcare professional administers this medication. Self-administration is strictly not advised.
  • The precise dosage and frequency of PEXOTRA 100MG INJECTION will be determined by your physician, carefully tailored to your specific medical condition and individual needs. Factors such as the severity of your condition, your overall health, and your response to the medication will all be taken into account when determining the optimal treatment plan.
  • The healthcare professional will closely monitor you during the infusion process to watch for any potential side effects or complications. If you have any concerns or experience any unusual symptoms during or after the infusion, it is important to inform them immediately. They are best equipped to address any issues that may arise and ensure your safety and well-being throughout the treatment.
  • It's important to maintain open communication with your doctor regarding your medical history and any other medications you may be taking. This information will help them make informed decisions about your treatment plan and minimize the risk of any potential drug interactions.

FAQs

What should I tell my doctor before starting PEXOTRA 100MG INJECTION?Arrow

Before starting PEXOTRA 100MG INJECTION, you should tell your doctor about any medical conditions you have, especially kidney or liver problems, as well as any medications you are taking, including over-the-counter drugs and supplements.

Can children or adults take PEXOTRA 100MG INJECTION?Arrow

No, PEXOTRA 100MG INJECTION is not recommended for children or adults under 18 years. Talk with your doctor for more information.

How often do I need to have blood tests while on PEXOTRA 100MG INJECTION?Arrow

You will need to have regular blood tests while taking PEXOTRA 100MG INJECTION to monitor your blood cell counts, blood uric acid level, and kidney function.

Can I continue my normal activities while on PEXOTRA 100MG INJECTION?Arrow

It depends on your circumstances and how you feel. You should discuss your activities and any concerns with your healthcare provider while under the treatment of PEXOTRA 100MG INJECTION.

How is PEXOTRA 100MG INJECTION administered?Arrow

A healthcare provider gives PEXOTRA 100MG INJECTION as an intravenous (IV) injection. The dose and frequency of the injections will depend on the patient's condition and other factors.

Why do I feel nauseous while taking PEXOTRA 100MG INJECTION?Arrow

Nausea is a common side effect of chemotherapy drugs, including PEXOTRA 100MG INJECTION. This happens because chemotherapy drugs can affect the lining of the stomach, leading to nausea and vomiting.

Does PEXOTRA 100MG INJECTION interact with other drugs?Arrow

PEXOTRA 100MG INJECTION has no known interactions with other drugs.

What advice should I follow while taking PEXOTRA 100MG INJECTION?Arrow

Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 3 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Notify your doctor immediately if you have undergone any radiotherapy or taken any vaccines and other medications before starting with PEXOTRA 100MG INJECTION because it might reduce the effectiveness of this medicine and may cause side effects. Inform your doctor if you have or had any history of heart disease, kidney problems,s or liver problems.

What is PEXOTRA 100MG INJECTION made of?Arrow

PEMETREXED is the molecule/combination used for making PEXOTRA 100MG INJECTION.

For what ailments/diseases/conditions is PEXOTRA 100MG INJECTION prescribed?Arrow

PEXOTRA 100MG INJECTION is prescribed for {Oncology} ailments/diseases/conditions.

References

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Eagle Pharmaceuticals, US Food and Drug Administration

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Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc)

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Marketer / Manufacturer Details

GLENMARK PHARMACEUTICALS LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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