RASBASE 1.5MG INJECTION
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RASBASE 1.5MG INJECTION
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RASBASE 1.5MG INJECTION

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RASBASE 1.5MG INJECTION

By HALSTED PHARMA PVT LTD

MRP

12800

₹5221

59.21 % OFF

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Product DetailsArrow

About RASBASE 1.5MG INJECTION

  • RASBASE 1.5MG INJECTION contains the active ingredient Rasburicase, classified as a uricolytic agent and used to manage acute hyperuricemia, a condition characterized by elevated uric acid levels in the blood. This medication is particularly vital for patients undergoing chemotherapy, where the breakdown of cancer cells can release substantial amounts of uric acid. Such a surge in uric acid can overwhelm the kidneys, potentially leading to kidney damage and other serious health complications. This injection works by rapidly breaking down uric acid, helping to prevent or treat hyperuricemia, especially in cases of tumor lysis syndrome, where a large number of cancer cells die within a short period.
  • It’s crucial to note that RASBASE 1.5MG INJECTION is generally not recommended for individuals with G6PD deficiency due to the risk of hemolysis, the destruction of red blood cells. Rasburicase can trigger this by generating reactive oxygen species that harm red blood cells. If you have been diagnosed with G6PD deficiency, it’s imperative to inform your healthcare provider before starting this medication, as you may be more susceptible to severe hemolytic anemia or methemoglobinemia, a condition involving an abnormal form of hemoglobin. Children undergoing chemotherapy for conditions like leukemia, lymphoma, or solid tumors are particularly vulnerable to hyperuricemia. RASBASE 1.5MG INJECTION helps mitigate the risk of kidney damage, seizures, and other complications associated with high uric acid levels in these young patients. Close monitoring for allergic reactions, hemolysis, and other potential side effects is essential during treatment.
  • Before initiating treatment with RASBASE 1.5MG INJECTION, inform your healthcare provider if you have any pre-existing kidney or liver conditions, vision problems, or lung issues. Regular blood tests will be necessary to monitor your condition and prevent potential complications. It is advisable to avoid alcohol consumption while on this medication, as it may exacerbate dizziness. If you are pregnant, suspect you might be pregnant, or are planning to conceive, consult your doctor before using this medication. RASBASE 1.5MG INJECTION is considered unsafe during pregnancy as it poses a risk to the developing fetus. Your healthcare provider will typically perform a pregnancy test before commencing treatment and will discuss effective birth control methods to be used during treatment and for at least two weeks after the final dose.

Uses of RASBASE 1.5MG INJECTION

  • Manage elevated uric acid levels during chemotherapy treatments.

Side Effects of RASBASE 1.5MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects include swelling of the face, lips, and tongue, as well as wheezing and breathing problems. Common side effects include nausea, vomiting, fever, swelling, anxiety, headache, abdominal pain, constipation, diarrhea, low phosphate levels in the blood, high levels of liver enzymes in the blood, and rashes.

  • Swelling of face, lips, tongue
  • Wheezing and breathing problems
  • Nausea, vomiting
  • Fever
  • Swelling
  • Anxiety
  • Headache
  • Abdominal pain
  • Constipation
  • Diarrhea
  • Low phosphate levels in the blood
  • High levels of liver enzymes in the blood
  • Rashes

Safety Advice for RASBASE 1.5MG INJECTIONArrow

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Pregnancy

UNSAFE

It is unsafe to use during pregnancy whether RASBASE 1.5MG INJECTION can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of RASBASE 1.5MG INJECTIONArrow

  • RASBASE 1.5MG INJECTION will be administered to you by a qualified healthcare professional in a hospital or clinical setting, ensuring your safety and well-being throughout the process.
  • The medication is delivered via intravenous infusion, meaning it's injected directly into a vein. Each infusion will take approximately 30 minutes to complete, and this process is typically repeated once daily for a maximum of 5 days.
  • Your doctor will determine the precise dosage, the method of administration (intravenous infusion), and the frequency of treatments based on a thorough evaluation of your specific medical condition, your overall health, and other relevant factors. It is essential to adhere to your doctor's prescribed regimen for optimal results.
  • Do not try to self-administer RASBASE 1.5MG INJECTION. It is imperative that a trained healthcare provider handles the administration of this medication to minimize potential risks and side effects. Your medical team will monitor you closely during and after each infusion to ensure your safety and to address any concerns promptly.

How to store RASBASE 1.5MG INJECTION?Arrow

  • Keep RASBASE 1.5MG INJ away from the reach of children and pets.
  • Store RASBASE 1.5MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RASBASE 1.5MG INJECTIONArrow

  • RASBASE 1.5MG INJECTION employs a sophisticated mechanism to address hyperuricemia, a condition characterized by elevated uric acid levels in the blood. Its primary function is to facilitate the conversion of uric acid into allantoin. Allantoin is a significantly more soluble substance compared to uric acid. This enhanced solubility is crucial because it allows the kidneys to efficiently filter and excrete allantoin from the body via urine. By converting uric acid into allantoin, RASBASE 1.5MG INJECTION effectively reduces the concentration of uric acid circulating in the bloodstream.
  • This reduction in uric acid levels is essential in preventing the formation of urate crystals, which can deposit in joints and tissues, leading to painful conditions like gout. Furthermore, by maintaining healthy uric acid levels, RASBASE 1.5MG INJECTION helps to protect the kidneys from damage associated with uric acid buildup. The overall effect is a decreased risk of hyperuricemia-related complications and improved joint and kidney health.
  • In essence, RASBASE 1.5MG INJECTION offers a targeted approach to managing uric acid levels. Its unique mechanism of action promotes the efficient elimination of uric acid, thereby alleviating the symptoms and preventing the progression of hyperuricemia and its associated health problems.

How to use RASBASE 1.5MG INJECTIONArrow

  • A healthcare professional will administer RASBASE 1.5MG INJECTION to you in a hospital or clinical setting. This medication is given as an intravenous infusion, meaning it's injected directly into a vein. The infusion process takes approximately 30 minutes, and it's typically administered once a day for a treatment period lasting up to 5 days.
  • Your doctor will determine the precise dosage, method of administration, and frequency of RASBASE 1.5MG INJECTION based on your specific medical condition, overall health, and other relevant factors. It's crucial to adhere to your doctor's instructions precisely. They will monitor your response to the medication and adjust the treatment plan as needed.
  • If you have any concerns or questions about the administration of RASBASE 1.5MG INJECTION, please don't hesitate to discuss them with your doctor or the healthcare professional administering the medication. They can provide you with detailed information and address any anxiety you may have. Remember, open communication with your healthcare team is essential for a successful treatment outcome.

FAQs

What is the purpose of RASBASE 1.5MG INJECTION?Arrow

RASBASE is used to prevent or treat hyperuricemia (high levels of uric acid in the blood) in patients who are undergoing cancer chemotherapy for leukemia, lymphoma, and solid tumor malignancies.

Is RASBASE 1.5MG INJECTION supportive therapy?Arrow

Yes, it is an important supportive therapy for patients undergoing chemotherapy to reduce the risk of complications associated with high levels of uric acid in the blood.

Who should not use RASBASE 1.5MG INJECTIONS?Arrow

RASBASE 1.5MG INJECTIONS are not indicated for those who have already developed acute gout or hyperuricemia due to conditions other than cancer chemotherapy.

What should I avoid while taking RASBASE 1.5MG INJECTIONS?Arrow

It is advised to avoid certain medications, such as allopurinol, which is used to lower uric acid levels. Using allopurinol with Rasbase together can reduce the effectiveness of Rasbase.

Whether Rasbase helps to protect people who are at high risk for tumor lysis syndrome (TLS)?Arrow

Yes, it is often used prophylactically in individuals who are at high risk for TLS due to their cancer chemotherapy.

Does RASBASE 1.5MG INJECTION interact with other drugs?Arrow

There are no known interactions of RASBASE 1.5MG INJECTION with other drugs.

What advice should I follow while taking RASBASE 1.5MG INJECTION?Arrow

Avoid driving and operating heavy machinery if you feel tired or weak during this treatment. Certain activities or conditions that can trigger gout attacks, such as fasting, rapid weight loss, and stress, should also be avoided while taking Rasbase. Foods that are high in purines should be avoided, such as red meat, organ meats, and some seafood, which can increase uric acid levels and reduce the effectiveness of Rasbase. It is important to avoid or limit consumption of these foods while taking Rasbase. Dehydration can reduce the effectiveness of the medication and increase the risk of side effects, so it is necessary to drink plenty of fluids, especially water, while taking this medicine. Smoking can cause oxidative stress in the body, which can lead to an increase in uric acid levels. It is advised to avoid smoking or using tobacco products while undergoing treatment with Rasbase.

What molecule is used to make RASBASE 1.5MG INJECTION?Arrow

RASBURICASE is the molecule used for making RASBASE 1.5MG INJECTION.

For which ailments/diseases/conditions is RASBASE 1.5MG INJECTION prescribed?Arrow

RASBASE 1.5MG INJECTION is prescribed for Oncology related ailments/diseases/conditions.

References

Book Icon

Sanofi-aventis groupe, Electronic Medicines Compendium (EMC)

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Sanofi-aventis U.S. LLC (no date) ELITEK., ELITEK (rasburicase) Powder for solution, for intravenous infusion. Available at:

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Sanofi S.p.A, Fasturtec name of the medicinal product qualitative and quantitative, Available at:

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Ueng, S. (2005) Rasburicase (Elitek): A novel agent for tumor lysis syndrome, Proceedings (Baylor University. Medical Center). U.S. National Library of Medicine. Available at:

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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