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RASBURNAT 1.5MG INJECTION

Name: RASBURNAT 1.5MG INJECTION
Brand: NATCO PHARMA LIMITED
Price: 4747 INR
Availability: InStock

RASBURNAT 1.5MG INJECTION

By NATCO PHARMA LIMITED

MRP

₹

8250

₹4747

42.46 % OFF

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Composition

RASBURICASE 1.5 MG

Product Details

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About RASBURNAT 1.5MG INJECTION

RASBURNAT 1.5MG INJECTION contains the active ingredient Rasburicase, and it belongs to the class of medications known as uricolytic agents, specifically designed to manage hyperuricemia. It is primarily used to treat acute hyperuricemia in patients undergoing chemotherapy. Chemotherapy can cause cancer cells to break down rapidly, releasing significant amounts of uric acid into the bloodstream, leading to hyperuricemia. This condition can result in kidney damage and other serious health complications. RASBURNAT 1.5MG INJECTION helps prevent and treat hyperuricemia, particularly in patients with tumor lysis syndrome, where a large number of cancer cells die within a short period.
Patients with G6PD deficiency should exercise caution, as RASBURNAT 1.5MG INJECTION can trigger hemolysis (destruction of red blood cells). This occurs because the medication generates reactive oxygen species, which damage red blood cells. Therefore, it's generally not recommended for individuals with G6PD deficiency. If you have this deficiency, inform your doctor before using this medicine, as you may be more susceptible to severe haemolytic anaemia or methemoglobinemia (an abnormal form of haemoglobin). Children receiving chemotherapy for leukaemia, lymphoma, or solid tumor malignancies are at risk of hyperuricemia, which can lead to kidney damage, seizures, and other complications. This medication effectively reduces uric acid levels in the blood, thereby treating hyperuricemia. Close monitoring is essential for children receiving RASBURNAT 1.5MG INJECTION to detect any signs of allergic reactions, hemolysis, or other side effects. Inform your healthcare provider if you have kidney or liver disease, vision problems, or lung problems. Regular blood tests will be conducted to prevent complications. Avoid alcohol consumption, as it may cause dizziness.
If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medication. RASBURNAT 1.5MG INJECTION is considered unsafe during pregnancy and can cause harm to the unborn fetus. Your healthcare provider will perform a pregnancy test before starting treatment with Rasburicase Injection. Discuss effective birth control methods with your doctor and use them for at least two weeks after the last dose. It is crucial to adhere to these precautions to ensure the safety of both the mother and the developing fetus. It is also essential to maintain proper hydration and follow dietary recommendations provided by your healthcare provider to manage uric acid levels effectively. Promptly report any unusual symptoms or side effects to your doctor for appropriate management.

Uses of RASBURNAT 1.5MG INJECTION

Manage elevated uric acid levels during chemotherapy treatments effectively.

Side Effects of RASBURNAT 1.5MG INJECTION

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. RASBURNAT 1.5MG INJECTION can cause both serious and common side effects.

Swelling of face, lips, tongue
Wheezing and breathing problems
Nausea, vomiting
Fever
Swelling
Anxiety
Headache
Abdominal pain
Constipation
Diarrhea
Low phosphate levels in the blood
High levels of liver enzymes in the blood
Rashes

Safety Advice for RASBURNAT 1.5MG INJECTION

Pregnancy

UNSAFE

It is unsafe to use during pregnancy whether RASBURNAT 1.5MG INJECTION can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Dosage of RASBURNAT 1.5MG INJECTION

A healthcare professional will administer the medication in a hospital environment to ensure proper monitoring and care. RASBURNAT 1.5MG INJECTION is administered intravenously, meaning it's injected directly into a vein. This infusion process typically takes about 30 minutes and is usually performed once a day for a maximum of 5 days.
The specific dosage, method of administration, and frequency of RASBURNAT 1.5MG INJECTION will be determined by your doctor. These decisions are carefully made based on your unique medical condition, overall health, and other relevant factors. It's crucial to follow your doctor's instructions precisely for the best possible outcome.
During the infusion, you will be closely monitored by medical staff. They will observe you for any potential side effects or adverse reactions. If you have any concerns or experience any unusual symptoms during or after the infusion, be sure to inform your healthcare provider immediately. They are there to ensure your safety and well-being throughout the treatment process.

How to store RASBURNAT 1.5MG INJECTION?

Keep RASBURNAT 1.5MG INJ away from the reach of children and pets.
Store RASBURNAT 1.5MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RASBURNAT 1.5MG INJECTION

RASBURNAT 1.5MG INJECTION is a medication designed to lower uric acid levels in the blood. It functions by converting uric acid, a naturally occurring substance in the body, into allantoin. Allantoin is significantly more soluble than uric acid, meaning it dissolves more easily in fluids.
This enhanced solubility allows the kidneys to efficiently filter allantoin from the bloodstream and excrete it through urine. By facilitating the conversion of uric acid to allantoin, RASBURNAT 1.5MG INJECTION effectively reduces the concentration of uric acid circulating in the body.
This reduction in uric acid is crucial for preventing and managing hyperuricemia, a condition characterized by abnormally high levels of uric acid in the blood. Hyperuricemia can lead to the formation of urate crystals, which can deposit in joints and tissues, causing gout and other related health problems. Therefore, RASBURNAT 1.5MG INJECTION helps to mitigate these risks by promoting the efficient removal of uric acid from the body.

How to use RASBURNAT 1.5MG INJECTION

A healthcare professional will administer this medication to you in a hospital or clinical setting. RASBURNAT 1.5MG INJECTION is administered as an intravenous infusion, meaning it's injected directly into a vein. The infusion process typically takes about 30 minutes, and it's given once daily for a treatment period that can last up to 5 days.
Your doctor will determine the precise dosage, the method of administration (intravenous infusion), and how often you receive RASBURNAT 1.5MG INJECTION. This decision is carefully made based on your specific medical condition, your overall health, and other relevant factors. It's essential to adhere to the prescribed schedule and dosage to ensure the medication works effectively.
The medical staff will closely monitor you during and after the infusion for any potential side effects or complications. If you have any concerns or experience any unusual symptoms, promptly inform your doctor or nurse. Regular blood tests may be conducted to assess how well the medication is working and to monitor your overall health throughout the treatment period.

FAQs

What is the purpose of RASBURNAT 1.5MG INJECTION?

RASBURNAT 1.5MG INJECTION is used to prevent or treat hyperuricemia (high levels of uric acid in the blood) in patients who are undergoing cancer chemotherapy for leukemia, lymphoma, and solid tumor malignancies.

Is RASBURNAT 1.5MG INJECTION supportive therapy?

Yes, it is an important supportive therapy for patients undergoing chemotherapy to reduce the risk of complications associated with high levels of uric acid in the blood.

Who should not use RASBURNAT 1.5MG INJECTION?

RASBURNAT 1.5MG INJECTION are not indicated for those who have already developed acute gout or hyperuricemia due to conditions other than cancer chemotherapy.

What should I avoid while taking RASBURNAT 1.5MG INJECTION?

It is advised to avoid certain medications, such as allopurinol, which is used to lower uric acid levels. Using allopurinol with Rasburicase together can reduce the effectiveness of rasburicase.

How does RASBURNAT 1.5MG INJECTION work?

RASBURNAT 1.5MG INJECTION works by converting uric acid into allantoin, a more soluble compound that can be easily excreted by the kidneys. This reduces the levels of uric acid in the blood and prevents the development of hyperuricemia.

Whether RASBURNAT 1.5MG INJECTION helps to protect people who are at high risk for tumor lysis syndrome (TLS)?

Yes, it is often used prophylactically in individuals who are at high risk for TLS due to their cancer chemotherapy.

Is there any interaction of RASBURNAT 1.5MG INJECTION with other drugs?

There are no known interactions of RASBURNAT 1.5MG INJECTION with other drugs.

What foods should I avoid while taking RASBURNAT 1.5MG INJECTION?

Foods that are high in purines should be avoided, such as red meat, organ meats, and some seafood, which can increase uric acid levels and reduce the effectiveness of RASBURNAT 1.5MG INJECTION. Avoid driving and operating heavy machinery if you feel tired or weak during this treatment. Certain activities or conditions that can trigger gout attacks, such as fasting, rapid weight loss, and stress, should also be avoided while taking Rasburicase. Dehydration can reduce the effectiveness of the medication and increase the risk of side effects, so it is necessary to drink plenty of fluids, especially water, while taking this medicine. Smoking can cause oxidative stress in the body, which can lead to an increase in uric acid levels. It is advised to avoid smoking or using tobacco products while undergoing treatment with RASBURNAT 1.5MG INJECTION.

Which molecule/combination is used for making RASBURNAT 1.5MG INJECTION?

RASBURICASE is the molecule/combination used for making RASBURNAT 1.5MG INJECTION.

For what type of cancer RASBURNAT 1.5MG INJECTION is prescribed?

RASBURNAT 1.5MG INJECTION is prescribed for Oncology.

References

Sanofi-aventis groupe, Electronic Medicines Compendium (EMC),

Sanofi-aventis U.S. LLC (no date) ELITEK., ELITEK (rasburicase) Powder for solution, for intravenous infusion. Available at:

Sanofi S.p.A, Fasturtec name of the medicinal product qualitative and quantitative, Available at:

Ueng, S. (2005) Rasburicase (Elitek): A novel agent for tumor lysis syndrome, Proceedings (Baylor University. Medical Center). U.S. National Library of Medicine. Available at:

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Marketer / Manufacturer Details

NATCO PHARMA LIMITED

Country of Origin -

India

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RASBURNAT 1.5MG INJECTION

RASBURNAT 1.5MG INJECTION

Product Details

About RASBURNAT 1.5MG INJECTION

Uses of RASBURNAT 1.5MG INJECTION

Side Effects of RASBURNAT 1.5MG INJECTION

Safety Advice for RASBURNAT 1.5MG INJECTION

Dosage of RASBURNAT 1.5MG INJECTION

How to store RASBURNAT 1.5MG INJECTION?

Benefits of RASBURNAT 1.5MG INJECTION

How to use RASBURNAT 1.5MG INJECTION

FAQs

What is the purpose of RASBURNAT 1.5MG INJECTION?

Is RASBURNAT 1.5MG INJECTION supportive therapy?

Who should not use RASBURNAT 1.5MG INJECTION?