REGRACE PLUS TABLET 10'S

How REGRACE PLUS TABLET 10'S Works

• REGRACE PLUS Tablet 10'S is a combination medicine containing pregabalin and methylcobalamin. It is primarily used to manage neuropathic pain, a type of chronic pain caused by damage to nerves. Understanding how each component works is crucial to appreciating the overall therapeutic effect of REGRACE PLUS.
• Pregabalin, an active ingredient in REGRACE PLUS, is an anticonvulsant and analgesic. Its primary mechanism involves binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, pregabalin modulates calcium influx at nerve terminals. This modulation results in a reduction in the release of several neurotransmitters, including glutamate, norepinephrine, and substance P. These neurotransmitters are involved in the transmission of pain signals. By decreasing their release, pregabalin helps to reduce the excitability of neurons and alleviate neuropathic pain. Moreover, pregabalin's action is selective, meaning it primarily affects overactive nerve cells without significantly impacting normal nerve function, thus minimizing the risk of widespread neurological side effects.
• Methylcobalamin, a form of vitamin B12, plays a vital role in nerve health and function. Unlike other forms of vitamin B12, methylcobalamin is the active coenzyme form, meaning it is readily available for use in the body's metabolic processes without requiring conversion. Methylcobalamin contributes to the synthesis of myelin, the protective sheath around nerve fibers. Myelin ensures efficient nerve impulse transmission. In cases of nerve damage or deficiency, myelin can degrade, leading to impaired nerve function and pain. Methylcobalamin supports the regeneration and maintenance of myelin, thereby improving nerve conduction velocity and reducing neuropathic pain. Additionally, methylcobalamin is involved in various metabolic pathways that support nerve cell health and reduce oxidative stress, further protecting nerves from damage.
• When combined in REGRACE PLUS, pregabalin and methylcobalamin offer a synergistic approach to managing neuropathic pain. Pregabalin reduces the transmission of pain signals by modulating neurotransmitter release, while methylcobalamin promotes nerve regeneration and protects against further damage. This dual action addresses both the symptomatic relief and the underlying causes of neuropathic pain. This combined effect can lead to more effective pain management compared to using either medication alone. REGRACE PLUS helps in improving overall nerve health, reducing pain, and improving the quality of life for individuals suffering from neuropathic pain.

REGRACE PLUS TABLET 10'S can cause several side effects, although not everyone experiences them. Common side effects may include nausea, vomiting, stomach upset, heartburn, diarrhea, constipation, loss of appetite, headache, dizziness, drowsiness, fatigue, skin rash, itching, and fluid retention (edema). Less common but potentially serious side effects include allergic reactions (such as hives, swelling of the face, lips, or tongue, difficulty breathing), liver problems (such as jaundice, dark urine, persistent fatigue), kidney problems (such as decreased urination, swelling in the legs or ankles), gastrointestinal bleeding (such as black, tarry stools, vomiting blood), and changes in blood pressure. Other reported side effects include anxiety, confusion, depression, insomnia, tremors, blurred vision, ringing in the ears (tinnitus), hair loss, and changes in blood sugar levels. This is not an exhaustive list, and it is important to consult a doctor if you experience any unusual or severe symptoms while taking this medication.

• If you miss a dose of REGRACE PLUS TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep REGRACE PLUS TAB 1X10 away from the reach of children and pets.
• Store REGRACE PLUS TAB 1X10 at room temperature.

• Take REGRACE PLUS TABLET 10'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or frequency, as this can increase the risk of side effects and not necessarily improve your condition faster. Consistency is key for optimal results.
• REGRACE PLUS TABLET 10'S is often taken to manage specific health conditions, and it's crucial to adhere to the full course of treatment even if you start feeling better. Prematurely stopping the medication can lead to a recurrence of symptoms or the development of resistance.
• To minimize potential stomach upset, take REGRACE PLUS TABLET 10'S with food or immediately after a meal, unless your doctor advises otherwise. This can also enhance the absorption of the medication into your bloodstream.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting REGRACE PLUS TABLET 10'S. Drug interactions can alter the effectiveness of the medication or increase the risk of adverse reactions. This includes over-the-counter medications.
• Store REGRACE PLUS TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective and safe for use. If you experience any unusual side effects, consult your doctor immediately.

• REGRACE PLUS TABLET 10'S can be taken with or without food, but it's generally recommended to take it after meals to minimize potential stomach upset. Consistent timing with meals can also help maintain stable blood levels of the medication. Consult your doctor for specific dietary advice tailored to your health condition.