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Content Reviewed By:
Dr. Rajesh Sharma
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
ZISPER PLUS TABLET 10'S may cause various side effects, which can range from common and mild to less common but more serious. It's important to be aware of these and consult your doctor if they persist or worsen. **Common Side Effects:** * **Drowsiness or Sleepiness:** Feeling unusually tired or sleepy. * **Dizziness:** Feeling lightheaded, especially when standing up quickly. * **Dry Mouth:** Reduced saliva production, leading to a dry sensation. * **Blurred Vision:** Difficulty focusing on objects. * **Constipation:** Infrequent or difficult bowel movements. * **Weight Gain:** Noticeable increase in body weight. * **Increased Appetite:** Feeling hungrier than usual. * **Nausea/Vomiting:** Upset stomach or throwing up. * **Headache:** Mild to moderate head pain. * **Restlessness or Agitation:** Feeling uneasy or irritable. * **Tremor:** Involuntary shaking, especially of the hands. * **Muscle Stiffness:** Feeling rigid or having difficulty moving muscles. * **Difficulty Sleeping (Insomnia):** Trouble falling or staying asleep. * **Increased Salivation:** More saliva production than usual. * **Fatigue:** General feeling of tiredness. **Less Common or Serious Side Effects (Seek medical attention immediately if experienced):** * **Involuntary Muscle Movements:** Uncontrolled movements, especially of the face, tongue, or limbs (e.g., tardive dyskinesia, dystonia, akathisia). * **Low Blood Pressure:** Dizziness or fainting, particularly when changing positions. * **Difficulty Urinating:** Trouble passing urine or inability to empty the bladder completely. * **Sexual Dysfunction:** Problems with sexual desire, erection, or ejaculation. * **Breast Enlargement (Gynecomastia):** Development of breast tissue in men. * **Milk Production (Galactorrhea):** Unexplained milk discharge from breasts. * **High Blood Sugar (Hyperglycemia):** Symptoms like increased thirst, frequent urination, and increased hunger. * **Fever with Muscle Stiffness:** High fever, severe muscle rigidity, confusion, sweating, and irregular heartbeat (possible Neuroleptic Malignant Syndrome - a rare but serious condition). * **Seizures:** Convulsions or fits. * **Swelling:** Swelling of hands, ankles, or feet. * **Skin Rash or Itching:** Allergic reactions. * **Changes in Heart Rhythm:** Irregular or fast heartbeat.

Allergies
UnsafeZisper Plus Tablet is unsafe if you have a known allergy to any of its ingredients.
Zisper Plus Tablet is a combination medicine primarily used in the treatment of schizophrenia and other psychotic disorders. It helps to manage symptoms like hallucinations, delusions, and disorganized thinking. The combination of Risperidone and Trihexyphenidyl helps manage both the primary condition and potential side effects like tremors or muscle stiffness.
Zisper Plus Tablet contains two active ingredients: Risperidone and Trihexyphenidyl.
Risperidone is an atypical antipsychotic that works by blocking certain dopamine and serotonin receptors in the brain, helping to reduce psychotic symptoms. Trihexyphenidyl is an anticholinergic medication that works by reducing the activity of a chemical called acetylcholine in the brain, which helps to relieve drug-induced muscle stiffness, tremors, and involuntary movements caused by Risperidone.
Common side effects may include dry mouth, blurred vision, constipation, dizziness, drowsiness, nausea, weight gain, tremors, and restlessness. Most side effects are mild and temporary.
Serious side effects, though rare, can include neuroleptic malignant syndrome (NMS), tardive dyskinesia (involuntary movements, especially of the face and tongue), significant weight gain, high blood sugar, and a drop in blood pressure when standing up. Seek immediate medical attention if you experience any severe or unusual symptoms.
Take Zisper Plus Tablet exactly as prescribed by your doctor. It can be taken with or without food. Swallow the tablet whole with water; do not crush, chew, or break it.
If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
No, you should not stop taking Zisper Plus Tablet suddenly without consulting your doctor. Abrupt discontinuation can lead to withdrawal symptoms or a return of your original symptoms. Your doctor will gradually reduce the dose if discontinuation is necessary.
While some immediate effects like drowsiness may be felt, the full therapeutic benefits of Zisper Plus Tablet for managing psychotic symptoms may take several weeks to become apparent. Continue taking it as prescribed even if you don't feel immediate improvement.
It is strongly advised to avoid alcohol consumption while taking Zisper Plus Tablet. Alcohol can increase the sedative effects of the medicine, leading to excessive drowsiness, dizziness, and impaired judgment.
Zisper Plus Tablet is not considered addictive in the same way as narcotics or sedatives. However, sudden discontinuation can lead to withdrawal-like symptoms, which is why gradual tapering under medical supervision is important.
Store Zisper Plus Tablet at room temperature, away from direct light and moisture. Keep it out of reach of children and pets. Do not freeze the medicine.
Yes, weight gain is a known side effect of Risperidone, one of the active ingredients in Zisper Plus. It's important to monitor your weight and discuss any concerns with your doctor. Lifestyle modifications (diet, exercise) may be recommended.
Generally, there are no specific dietary restrictions. However, maintaining a balanced diet is recommended to manage potential weight gain side effects. Avoid grapefruit juice as it may interact with some medications, though direct interaction with Zisper Plus is not commonly highlighted. Always consult your doctor for specific advice.
The use of Zisper Plus Tablet in children should be determined by a specialist. Risperidone is approved for certain conditions in children and adolescents (e.g., irritability associated with autistic disorder, schizophrenia in adolescents). Trihexyphenidyl use in children requires careful consideration. Always follow your doctor's instructions regarding pediatric use.
Zisper Plus Tablet can cause drowsiness, dizziness, and blurred vision, especially when you first start taking it or if the dose is changed. Therefore, it is advisable to avoid driving or operating heavy machinery until you know how the medicine affects you.
Zisper Plus Tablet can be taken with or without food. Taking it with food might help reduce stomach upset in some individuals, but it does not significantly affect the absorption or efficacy of the medicine. Just ensure consistency in your dosing schedule.
Zisper Plus is a specific brand name for a combination of Risperidone and Trihexyphenidyl. Other brands might contain only Risperidone (e.g., Risperdal) or the same combination under a different brand name. The active ingredients and their dosage are key. Always consult your doctor or pharmacist about equivalent medications.
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India

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