SACUMERIT 50MG TABLET 14'S
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SACUMERIT 50MG TABLET 14'S

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SACUMERIT 50MG TABLET 14'S

By PRECISE BIOPHARMA PVT LTD

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249

₹140

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About SACUMERIT 50MG TABLET 14'S

  • SACUMERIT 50MG TABLET is a prescription medication designed to help manage blood sugar levels in adults with type 2 diabetes. It contains Sacubitril and Valsartan as active ingredients, which work together to improve glycemic control.
  • Sacubitril belongs to a class of medications called neprilysin inhibitors. It works by increasing the levels of certain natural substances in the body that help to lower blood sugar. Valsartan is an angiotensin receptor blocker (ARB) that helps to relax blood vessels and improve blood flow, further contributing to blood sugar management. This combination provides a dual-action approach to managing type 2 diabetes.
  • SACUMERIT 50MG TABLET is typically used in conjunction with diet and exercise to achieve optimal blood sugar control. It is usually taken once or twice daily, as directed by your healthcare provider. Adhering to the prescribed dosage and schedule is crucial for the medication's effectiveness. Common side effects may include headache, dizziness, and nausea. It is important to consult with your doctor if these side effects persist or worsen.
  • Before starting SACUMERIT 50MG TABLET, inform your doctor about any other medical conditions you have, especially kidney or liver problems, heart failure, or a history of angioedema. Also, disclose all other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. Regular monitoring of blood sugar levels and kidney function is recommended while taking this medication.
  • SACUMERIT 50MG TABLET offers a valuable tool for managing type 2 diabetes by targeting multiple pathways involved in blood sugar regulation. When used as part of a comprehensive treatment plan that includes lifestyle modifications and regular medical check-ups, it can help improve overall health and reduce the risk of diabetes-related complications.

Uses of SACUMERIT 50MG TABLET 14'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling blood sugar levels after meals
  • May be used in combination with other diabetes medications

How SACUMERIT 50MG TABLET 14'S Works

  • SACUMERIT 50MG TABLET 14'S contains sacubitril and valsartan. These two medicines work together to treat heart failure. Heart failure happens when the heart cannot pump enough blood to meet the body's needs. This can lead to symptoms like shortness of breath, fatigue, and swelling in the legs and ankles. SACUMERIT helps to alleviate these symptoms and improve heart function.
  • Sacubitril belongs to a class of medicines called neprilysin inhibitors. Neprilysin is an enzyme in the body that breaks down certain natural substances (natriuretic peptides) that help to regulate blood pressure and sodium levels. By inhibiting neprilysin, sacubitril increases the levels of these beneficial peptides. These peptides promote vasodilation (widening of blood vessels), reduce sodium retention, and decrease the workload on the heart. This leads to a decrease in blood pressure and an improvement in heart function.
  • Valsartan belongs to a class of medicines called angiotensin II receptor blockers (ARBs). Angiotensin II is a hormone in the body that causes blood vessels to constrict, increasing blood pressure. It also stimulates the release of aldosterone, a hormone that causes the kidneys to retain sodium and water. Valsartan blocks the effects of angiotensin II, leading to vasodilation, reduced sodium and water retention, and decreased blood pressure. This further reduces the workload on the heart and improves its function.
  • The combination of sacubitril and valsartan in SACUMERIT provides a dual mechanism of action that is more effective than either medicine alone. By increasing the levels of beneficial natriuretic peptides and blocking the harmful effects of angiotensin II, SACUMERIT helps to reduce the strain on the heart, improve blood flow, and reduce the symptoms of heart failure. This can lead to a better quality of life for people with heart failure.
  • In essence, SACUMERIT works by enhancing the body's natural mechanisms to protect the heart and blood vessels. It widens blood vessels, helps the body get rid of excess sodium and water, and reduces the harmful effects of hormones that can worsen heart failure. All these effects combine to ease the strain on the failing heart and improve its ability to pump blood effectively. This combined action helps to improve symptoms, reduce hospitalizations, and prolong life in patients with heart failure.

Side Effects of SACUMERIT 50MG TABLET 14'SArrow

Common side effects of Sacumerit 50mg Tablet may include nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, headache, dizziness, fatigue, and skin rash. Less common but potentially serious side effects include liver problems (such as jaundice, dark urine, persistent fatigue), allergic reactions (such as rash, itching, swelling, severe dizziness, trouble breathing), and changes in blood sugar levels. If you experience any unusual or severe symptoms, consult your doctor immediately.

Safety Advice for SACUMERIT 50MG TABLET 14'SArrow

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Allergies

Allergies

Use caution if you are allergic to Sacumerit 50mg Tablet.

Dosage of SACUMERIT 50MG TABLET 14'SArrow

  • The recommended dosage of SACUMERIT 50MG TABLET 14'S varies depending on individual patient factors, including the severity of the condition being treated, other medical conditions, and response to treatment. It is crucial to adhere strictly to your physician's instructions regarding dosage and duration of treatment. Do not self-adjust the dose or discontinue the medication without consulting your healthcare provider.
  • Typically, the initial dose of SACUMERIT 50MG TABLET 14'S is 50mg taken orally, once daily. Your doctor may adjust the dosage based on your individual needs and response to the medication. In some cases, the dosage may be increased gradually to a maximum of 100mg per day. It's important to maintain consistent timing when taking the medication each day, preferably at the same time.
  • SACUMERIT 50MG TABLET 14'S can be taken with or without food. However, it is important to maintain a consistent pattern. If you experience any stomach upset, taking it with food might help. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • If you have kidney or liver problems, your doctor may need to adjust your dosage. Regular monitoring of kidney and liver function may be necessary while you are taking SACUMERIT 50MG TABLET 14'S. Always inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with SACUMERIT 50MG TABLET 14'S. Take 'SACUMERIT 50MG TABLET 14'S' only as per the prescription by your physician only

What if I miss my dose of SACUMERIT 50MG TABLET 14'S?Arrow

  • If you miss a dose of Sacumerit 50mg Tablet 14'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store SACUMERIT 50MG TABLET 14'S?Arrow

  • Keep SACUMERIT 50MG TAB 1X14 away from the reach of children and pets.
  • Store SACUMERIT 50MG TAB 1X14 at room temperature.

Benefits of SACUMERIT 50MG TABLET 14'SArrow

  • SACUMERIT 50MG TABLET 14'S is primarily prescribed for the management of type 2 diabetes mellitus, particularly in individuals whose blood sugar levels are not adequately controlled through diet and exercise alone. It belongs to a class of medications known as dipeptidyl peptidase-4 (DPP-4) inhibitors, which work by increasing the levels of incretin hormones in the body. These hormones help to regulate blood sugar by stimulating insulin release from the pancreas and reducing the production of glucose by the liver.
  • One of the key benefits of SACUMERIT 50MG TABLET 14'S is its ability to improve glycemic control. By enhancing the action of incretin hormones, it helps to lower both fasting and postprandial (after-meal) blood sugar levels. This can lead to a reduction in HbA1c, a measure of average blood sugar control over a period of 2-3 months. Effective glycemic control is crucial in preventing or delaying the long-term complications of diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular disease.
  • Another significant advantage of SACUMERIT 50MG TABLET 14'S is its relatively low risk of causing hypoglycemia (low blood sugar) compared to some other diabetes medications, such as sulfonylureas. This is because its mechanism of action is glucose-dependent, meaning that it primarily stimulates insulin release when blood sugar levels are elevated. This makes it a safer option for many patients, especially those who are at risk of experiencing hypoglycemic episodes.
  • SACUMERIT 50MG TABLET 14'S is often used as part of a combination therapy, meaning it can be taken along with other diabetes medications, such as metformin or thiazolidinediones, to achieve better blood sugar control. This allows healthcare providers to tailor treatment plans to meet the individual needs of their patients. It is also available in a fixed-dose combination with metformin, which can simplify the medication regimen and improve adherence.
  • In addition to its effects on blood sugar, SACUMERIT 50MG TABLET 14'S may also have some beneficial effects on other aspects of metabolic health. Some studies have suggested that it may help to improve lipid profiles (cholesterol and triglycerides) and reduce blood pressure, although more research is needed to confirm these effects. Furthermore, it is generally well-tolerated, with a low incidence of side effects. Common side effects may include headache, nausea, and upper respiratory tract infections, but these are usually mild and transient.
  • SACUMERIT 50MG TABLET 14'S offers a valuable tool for managing type 2 diabetes by improving blood sugar control, reducing the risk of hypoglycemia, and providing a versatile option for combination therapy. Its benefits extend beyond glycemic control, potentially offering some positive effects on metabolic health, making it an important medication for individuals with type 2 diabetes.

How to use SACUMERIT 50MG TABLET 14'SArrow

  • SACUMERIT 50MG TABLET 14'S is an oral medication designed to help manage blood sugar levels in individuals with type 2 diabetes. To maximize its effectiveness and minimize potential side effects, it's crucial to adhere to your doctor's instructions regarding dosage and timing.
  • Typically, SACUMERIT is taken once or twice daily, ideally before meals. This helps to control the rise in blood sugar that occurs after eating. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this could affect how the medication is released into your system.
  • Consistency is key when taking SACUMERIT. Try to take it at the same time(s) each day to help you remember. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • SACUMERIT works best when combined with a healthy diet and regular exercise. Follow your doctor's or dietitian's recommendations for a balanced meal plan and aim for at least 30 minutes of moderate-intensity exercise most days of the week. Regular monitoring of your blood sugar levels is also essential while taking SACUMERIT. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking, as they may interact with SACUMERIT. If you experience any unusual side effects, such as severe abdominal pain, nausea, vomiting, or persistent fatigue, contact your doctor immediately. Store SACUMERIT at room temperature, away from moisture and heat, and out of reach of children.
  • It's also important to note that Sacumerit is not a replacement for insulin in type 1 diabetes. If you have type 1 diabetes, you will still need insulin to manage your blood sugar levels. Talk to your doctor about the best treatment plan for you.
  • While taking this medication, it is important to be aware of the symptoms of low blood sugar (hypoglycemia), which can include shakiness, sweating, dizziness, and confusion. If you experience any of these symptoms, it is important to eat or drink something containing sugar immediately.

Quick Tips for SACUMERIT 50MG TABLET 14'SArrow

  • Take Sacumerit 50mg Tablet as prescribed by your doctor. It's usually taken once daily, with or without food, but try to take it at the same time each day to maintain a consistent level in your body and help you remember.
  • Sacumerit helps control blood sugar levels in adults with type 2 diabetes. It works best when combined with a healthy diet and regular exercise. Don't skip meals or suddenly change your diet while taking this medication.
  • Be aware of the potential side effects. Common side effects include headache, hypoglycemia (low blood sugar), and upper respiratory tract infection. If you experience any severe or persistent side effects, inform your doctor immediately.
  • Monitor your blood sugar regularly as directed by your doctor, especially when you first start taking Sacumerit. This helps you and your doctor understand how well the medication is working and adjust the dosage if needed. Keep a record of your blood sugar readings.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Sacumerit can interact with other drugs, potentially affecting how they work or increasing the risk of side effects. This includes over-the-counter medications.
  • If you have kidney problems, liver problems, or a history of pancreatitis, discuss these conditions with your doctor before starting Sacumerit. Dosage adjustments may be necessary.
  • Stay hydrated by drinking plenty of water throughout the day. This helps your body function properly and can also help manage some of the potential side effects of the medication.
  • If you are planning to have surgery, including dental surgery, inform your doctor and dentist that you are taking Sacumerit. It may be necessary to temporarily discontinue the medication before the procedure.
  • Store Sacumerit 50mg Tablets in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets.
  • Continue to follow your doctor's recommendations for lifestyle modifications, such as diet and exercise, even while taking Sacumerit. Medication is just one part of managing diabetes, and a healthy lifestyle plays a crucial role.

Food Interactions with SACUMERIT 50MG TABLET 14'SArrow

  • SACUMERIT 50MG TABLET 14'S does not have any known significant interactions with food. It can be taken with or without food. However, it is always recommended to follow your doctor's advice regarding the timing and method of taking this medication.

FAQs

What is the use of Sacumerit 50mg Tablet 14'S?Arrow

Sacumerit 50mg Tablet 14'S is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

How does Sacumerit 50mg Tablet 14'S work?Arrow

Sacumerit 50mg Tablet 14'S belongs to a class of medicines called DPP-4 inhibitors. It works by increasing the amount of insulin released from the pancreas and decreasing the amount of glucose produced by the body.

What are the common side effects of Sacumerit 50mg Tablet 14'S?Arrow

Common side effects of Sacumerit 50mg Tablet 14'S include headache, runny or stuffy nose, sore throat, and upper respiratory tract infection.

Can Sacumerit 50mg Tablet 14'S be taken with or without food?Arrow

Sacumerit 50mg Tablet 14'S can be taken with or without food, as directed by your doctor.

Is Sacumerit 50mg Tablet 14'S safe for patients with kidney disease?Arrow

Sacumerit 50mg Tablet 14'S should be used with caution in patients with kidney disease. Dose adjustments may be required. Please consult your doctor.

Is Sacumerit 50mg Tablet 14'S safe during pregnancy?Arrow

The safety of Sacumerit 50mg Tablet 14'S during pregnancy has not been established. Pregnant women should consult their doctor before using it.

How to store Sacumerit 50mg Tablet 14'S?Arrow

Store Sacumerit 50mg Tablet 14'S at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

What should I do if I miss a dose of Sacumerit 50mg Tablet 14'S?Arrow

If you miss a dose of Sacumerit 50mg Tablet 14'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can Sacumerit 50mg Tablet 14'S be taken with other diabetes medications?Arrow

Sacumerit 50mg Tablet 14'S can be taken with other diabetes medications, but only under the advice of a doctor. Some combinations may cause unwanted side effects.

Does Sacumerit 50mg Tablet 14'S cause weight gain?Arrow

Sacumerit 50mg Tablet 14'S does not typically cause weight gain. However, if you experience unusual weight gain, consult your doctor.

Can Sacumerit 50mg Tablet 14'S cause low blood sugar (hypoglycemia)?Arrow

Sacumerit 50mg Tablet 14'S is not likely to cause hypoglycemia on its own, but the risk may increase when it is used in combination with other diabetes medications, such as insulin or sulfonylureas.

What is the maximum daily dose of Sacumerit 50mg Tablet 14'S?Arrow

The maximum daily dose of Sacumerit 50mg Tablet 14'S is typically 100mg, but it can vary depending on individual needs and concomitant medications. Follow your doctor's instructions.

Is it safe to consume alcohol while taking Sacumerit 50mg Tablet 14'S?Arrow

Consuming alcohol while taking Sacumerit 50mg Tablet 14'S may increase the risk of low blood sugar. Consult your doctor before consuming alcohol.

What is the composition of Sacumerit 50mg Tablet 14'S?Arrow

Sacumerit 50mg Tablet 14'S contains saxagliptin as the active ingredient.

Can Sacumerit 50mg Tablet 14'S cause heart failure?Arrow

Some studies have suggested that Sacumerit 50mg Tablet 14'S may increase the risk of heart failure, especially in patients with pre-existing heart conditions. Seek immediate medical attention if you experience symptoms such as shortness of breath or swelling in the legs.

References

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FDA - ENTRESTO (sacubitril and valsartan) tablets, for oral use. Full Prescribing Information. Novartis Pharmaceuticals Corporation. 2015.

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European Medicines Agency - ENTRESTO. Summary of Product Characteristics.

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McMurray JJ, Packer M, Desai AS, et al. Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure. N Engl J Med. 2014;371(11):993-1004.

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Packer M, McMurray JJ, Desai AS, et al. Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation. 2015;131(1):54-61.

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Seferovic PM, Ponikowski P, Anker SD, et al. Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2019;21(10):1169-1186.

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DrugBank - Sacubitril. Detailed drug information, mechanism of action, and interactions.

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DrugBank - Valsartan. Detailed drug information, mechanism of action, and interactions.

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RxList - Entresto side effects, drug center.

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