SACUSAFE 50MG TABLET 10'S
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SACUSAFE 50MG TABLET 10'S
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SACUSAFE 50MG TABLET 10'S

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SACUSAFE 50MG TABLET 10'S

By ACMEDIX PHARMA LLP

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125

₹106.25

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About SACUSAFE 50MG TABLET 10'S

  • SACUSAFE 50MG TABLET is a medication primarily used to manage heart failure. It combines two active ingredients: sacubitril and valsartan. Sacubitril belongs to a class of medications called neprilysin inhibitors, while valsartan is an angiotensin receptor blocker (ARB). This combination works synergistically to protect the heart from failure.
  • The primary action of SACUSAFE 50MG TABLET is to relax blood vessels, making it easier for the heart to pump blood throughout the body. This reduces strain on the heart and improves its efficiency. Sacubitril enhances the levels of natriuretic peptides, which promote sodium and water excretion, further reducing blood volume and pressure. Valsartan blocks the effects of angiotensin II, a hormone that narrows blood vessels and increases blood pressure.
  • SACUSAFE 50MG TABLET is typically prescribed for individuals with chronic heart failure who experience symptoms such as shortness of breath, fatigue, and swelling in the ankles and feet. It helps to alleviate these symptoms and improve overall quality of life. The usual dosage is one tablet twice daily, but it's crucial to follow your doctor's specific instructions regarding dosage and administration.
  • Before taking SACUSAFE 50MG TABLET, inform your doctor about any pre-existing medical conditions, especially kidney or liver disease, low blood pressure, or a history of angioedema (swelling of the face, lips, tongue, or throat). Also, disclose all other medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. Common side effects may include dizziness, lightheadedness, and low blood pressure. If you experience any severe or persistent side effects, seek medical attention immediately.
  • SACUSAFE 50MG TABLET should be stored at room temperature, away from moisture and heat. Keep it out of reach of children. It's essential to continue taking this medication as prescribed, even if you feel better, to maintain its benefits and prevent worsening of heart failure. Regular check-ups with your doctor are necessary to monitor your progress and adjust your treatment plan as needed. This medication is a prescription drug, and purchasing it without a valid prescription is illegal. Always consult your healthcare provider for advice.

Uses of SACUSAFE 50MG TABLET 10'S

  • Treatment of Heart Failure
  • Management of Chronic Heart Failure
  • Reducing the Risk of Hospitalization due to Heart Failure
  • Reducing the Risk of Cardiovascular Death
  • Improving Life Expectancy in Patients with Reduced Ejection Fraction

How SACUSAFE 50MG TABLET 10'S Works

  • SACUSAFE 50MG TABLET 10'S is a combination medication containing sacubitril and valsartan. It is primarily used to treat heart failure with reduced ejection fraction (HFrEF). To understand how Sacusafe works, it's essential to consider the individual roles of its components: sacubitril and valsartan.
  • **Valsartan:** Valsartan belongs to a class of drugs called angiotensin II receptor blockers (ARBs). Angiotensin II is a hormone that causes blood vessels to constrict, leading to increased blood pressure and strain on the heart. Valsartan works by blocking the effects of angiotensin II. By doing so, it helps to relax blood vessels, reduce blood pressure, and decrease the workload on the heart. This makes it easier for the heart to pump blood and improves overall cardiac function.
  • **Sacubitril:** Sacubitril is a neprilysin inhibitor. Neprilysin is an enzyme that breaks down several beneficial substances in the body, including natriuretic peptides. Natriuretic peptides (such as atrial natriuretic peptide or ANP and B-type natriuretic peptide or BNP) help to regulate blood volume and sodium levels, and they promote vasodilation (widening of blood vessels). By inhibiting neprilysin, sacubitril increases the levels of these beneficial natriuretic peptides.
  • **Synergistic Effect:** The combination of sacubitril and valsartan in Sacusafe provides a synergistic effect. Valsartan blocks the harmful effects of angiotensin II, while sacubitril enhances the beneficial effects of natriuretic peptides. This dual action leads to several positive outcomes for patients with HFrEF. These outcomes include vasodilation, reduced sodium and fluid retention, decreased blood pressure, and reduced strain on the heart. The overall effect is improved heart function, reduced symptoms of heart failure (such as shortness of breath and fatigue), and a decreased risk of hospitalization and death associated with heart failure.
  • SACUSAFE 50MG TABLET 10'S helps the heart to pump blood more efficiently and reduces the strain on the heart muscle. This medicine promotes vasodilation, reduces sodium and fluid retention, and lowers blood pressure. SACUSAFE 50MG TABLET 10'S is typically used in conjunction with other heart failure medications, such as beta-blockers and diuretics, to provide comprehensive management of the condition. It is crucial to take Sacusafe exactly as prescribed by your healthcare provider and to attend regular check-ups to monitor your progress and adjust your treatment plan as needed.

Side Effects of SACUSAFE 50MG TABLET 10'SArrow

The following side effects may occur while using SACUSAFE 50MG TABLET 10'S. This is not an exhaustive list, and you may experience other side effects not mentioned here. **Common Side Effects:** * Hypotension (low blood pressure) * Hyperkalemia (high potassium levels in the blood) * Renal impairment (kidney problems) * Dizziness * Cough * Angioedema (swelling of the face, lips, tongue, or throat) * Diarrhea * Fatigue **Uncommon Side Effects:** * Nausea * Headache * Muscle cramps * Rash * Gastritis (inflammation of the stomach lining) * Anemia (low red blood cell count) * Neutropenia (low white blood cell count) **Rare Side Effects:** * Severe allergic reaction * Liver problems **Seek immediate medical attention if you experience:** * Difficulty breathing * Swelling of the face, lips, tongue, or throat * Severe dizziness or fainting * Persistent cough * Signs of kidney problems (such as decreased urination) This is not a complete list. If you experience any bothersome or unusual symptoms, consult your doctor or pharmacist.

Safety Advice for SACUSAFE 50MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Sacusafe 50MG Tablet 10'S if you are allergic to it.

Dosage of SACUSAFE 50MG TABLET 10'SArrow

  • The recommended dosage of 'SACUSAFE 50MG TABLET 10'S' varies depending on individual patient factors, including the severity of the condition being treated, kidney function, and other medications being taken. It is crucial to adhere strictly to your doctor's prescribed dosage and schedule. Typically, the starting dose is 50mg, but your doctor might adjust this based on your response and tolerance to the medication.
  • For most patients, 'SACUSAFE 50MG TABLET 10'S' is administered orally, and can be taken with or without food. Consistent timing is important for maintaining stable blood levels of the drug. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • It is vital to consult your physician before making any changes to your dosage. Self-adjusting the dosage can lead to adverse effects or reduced effectiveness of the medication. Long-term use of 'SACUSAFE 50MG TABLET 10'S' requires periodic monitoring of kidney function and other relevant health indicators, as determined by your healthcare provider. Always inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential drug interactions.
  • Take 'SACUSAFE 50MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of SACUSAFE 50MG TABLET 10'S?Arrow

  • If you miss a dose of Sacusafe 50mg Tablet, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How to store SACUSAFE 50MG TABLET 10'S?Arrow

  • Keep SACUSAFE 50MG TAB 1X10 away from the reach of children and pets.
  • Store SACUSAFE 50MG TAB 1X10 at room temperature.

Benefits of SACUSAFE 50MG TABLET 10'SArrow

  • SACUSAFE 50MG TABLET 10'S is a combination medication containing Sacubitril and Valsartan, primarily used to treat heart failure with reduced ejection fraction (HFrEF). It works by relaxing blood vessels, making it easier for the heart to pump blood throughout the body. This results in a multitude of benefits for individuals suffering from this condition.
  • One of the most significant benefits of SACUSAFE 50MG TABLET 10'S is its ability to reduce the risk of hospitalization for heart failure. Clinical trials have demonstrated a significant decrease in the number of hospital admissions among patients taking this medication compared to those on traditional treatments. This not only improves the patient's quality of life but also reduces the economic burden associated with frequent hospital stays.
  • SACUSAFE 50MG TABLET 10'S also helps improve the symptoms of heart failure, such as shortness of breath, fatigue, and swelling in the ankles and feet. By reducing the strain on the heart and improving blood flow, patients often experience a noticeable improvement in their ability to perform daily activities. This can lead to a more active and fulfilling lifestyle.
  • Furthermore, SACUSAFE 50MG TABLET 10'S has been shown to reduce the risk of cardiovascular death in patients with HFrEF. This is a crucial benefit, as heart failure is a life-threatening condition. By protecting the heart and blood vessels, this medication helps prolong life expectancy and improve overall survival rates.
  • Another key advantage of SACUSAFE 50MG TABLET 10'S is its potential to improve kidney function in some patients with heart failure. Heart failure and kidney disease are often intertwined, and improving one can positively impact the other. This medication may help to protect the kidneys from further damage and improve their ability to filter waste products from the blood.
  • SACUSAFE 50MG TABLET 10'S offers a comprehensive approach to managing heart failure with reduced ejection fraction. Its multifaceted benefits, including reduced hospitalization risk, improved symptoms, decreased cardiovascular death risk, and potential kidney function improvement, make it a valuable treatment option for individuals suffering from this debilitating condition. As always, it's important to consult with a healthcare professional to determine if SACUSAFE 50MG TABLET 10'S is the right medication for your specific needs and to discuss any potential risks or side effects.

How to use SACUSAFE 50MG TABLET 10'SArrow

  • SACUSAFE 50MG TABLET 10'S should be taken exactly as prescribed by your doctor. Do not alter the dosage or frequency of administration without consulting your healthcare provider. This medication is typically administered orally with a glass of water. It can be taken with or without food, but maintaining a consistent schedule each day is advisable for optimal absorption and effectiveness.
  • Before initiating treatment with SACUSAFE 50MG TABLET 10'S, inform your doctor about any pre-existing medical conditions you have, especially kidney or liver problems, as dosage adjustments may be necessary. Disclose all other medications, supplements, or herbal products you are currently taking to avoid potential drug interactions. Pay close attention to your body's response to the medication, and promptly report any unusual or bothersome side effects to your physician.
  • To ensure you do not miss a dose, take SACUSAFE 50MG TABLET 10'S at the same time every day. If you happen to miss a dose, take it as soon as you remember, unless it's nearly time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate for a missed one. Adherence to the prescribed treatment plan is vital for achieving the desired therapeutic outcomes and minimizing potential risks.
  • If you're taking this medication for a specific condition, monitor your symptoms regularly and keep your doctor informed about any changes. Regular check-ups and lab tests may be required to assess the effectiveness of the treatment and identify any potential adverse effects early on. Always complete the full course of treatment as prescribed, even if you start feeling better before the medication is finished. Discontinuing the medication prematurely can lead to a recurrence of the condition or the development of drug resistance.
  • Store SACUSAFE 50MG TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Properly dispose of any unused medication or expired tablets according to local regulations. If you have any questions or concerns regarding the use of SACUSAFE 50MG TABLET 10'S, consult your doctor or pharmacist for further guidance.

Quick Tips for SACUSAFE 50MG TABLET 10'SArrow

  • Take Sacusafe 50mg Tablet exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures optimal effectiveness and minimizes potential side effects.
  • Sacusafe 50mg Tablet can be taken with or without food, but it's best to choose one method and stick to it consistently. This helps maintain a stable level of the medication in your body.
  • If you miss a dose of Sacusafe 50mg Tablet, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting Sacusafe 50mg Tablet. This is crucial to avoid potential drug interactions that could reduce the effectiveness of Sacusafe or increase the risk of side effects.
  • Store Sacusafe 50mg Tablet at room temperature, away from direct sunlight, heat, and moisture. Keep it out of reach of children and pets to prevent accidental ingestion.
  • If you experience any bothersome or persistent side effects while taking Sacusafe 50mg Tablet, such as nausea, headache, or dizziness, consult your doctor promptly. They can assess the situation and provide appropriate guidance or adjustments to your treatment plan.
  • Avoid consuming alcohol while taking Sacusafe 50mg Tablet, as it can potentially increase the risk or severity of certain side effects. Alcohol interaction can impact the effectiveness of the medication.
  • Do not stop taking Sacusafe 50mg Tablet abruptly, even if you start feeling better, without consulting your doctor. Suddenly stopping the medication may lead to a relapse of your condition or withdrawal symptoms. Your doctor will guide you on how to gradually reduce the dosage if necessary.

Food Interactions with SACUSAFE 50MG TABLET 10'SArrow

  • SACUSAFE 50MG TABLET 10'S can be taken with or without food, but it is advisable to take it at a fixed time to maintain consistent blood levels. Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of liver problems or other side effects. If you experience any stomach upset, try taking it with food.

FAQs

What is Sacusafe 50mg Tablet used for?Arrow

Sacusafe 50mg Tablet is primarily used to treat heart failure with reduced ejection fraction (HFrEF). It helps to reduce the risk of hospitalization and cardiovascular death in patients with chronic heart failure.

How should I take Sacusafe 50mg Tablet?Arrow

Take Sacusafe 50mg Tablet as prescribed by your doctor. Usually, it is taken twice a day, with or without food. Follow the dosage instructions carefully and do not stop taking it without consulting your doctor.

What are the common side effects of Sacusafe 50mg Tablet?Arrow

Common side effects may include low blood pressure (hypotension), high potassium levels (hyperkalemia), dizziness, and kidney problems. If you experience any severe or persistent side effects, contact your doctor.

Can I take Sacusafe 50mg Tablet with other medications?Arrow

It is important to inform your doctor about all the medications you are currently taking, including over-the-counter drugs and herbal supplements. Sacusafe 50mg Tablet may interact with certain medications, such as ACE inhibitors and NSAIDs.

What should I do if I miss a dose of Sacusafe 50mg Tablet?Arrow

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How should Sacusafe 50mg Tablet be stored?Arrow

Store Sacusafe 50mg Tablet at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can Sacusafe 50mg Tablet cause dizziness?Arrow

Yes, dizziness is a common side effect of Sacusafe 50mg Tablet. If you feel dizzy, sit or lie down until the dizziness passes. Avoid activities that require alertness until you know how the medication affects you.

Is Sacusafe 50mg Tablet safe to use during pregnancy?Arrow

Sacusafe 50mg Tablet is not recommended for use during pregnancy. It may cause harm to the developing fetus. Consult your doctor if you are pregnant or planning to become pregnant.

Can Sacusafe 50mg Tablet affect kidney function?Arrow

Yes, Sacusafe 50mg Tablet can affect kidney function, especially in patients with pre-existing kidney problems. Your doctor may monitor your kidney function regularly while you are taking this medication.

What is the composition of Sacusafe 50mg Tablet?Arrow

Sacusafe 50mg Tablet contains Sacubitril and Valsartan as its active ingredients. It is a combination medicine used to treat heart failure.

Are there any specific dietary restrictions while taking Sacusafe 50mg Tablet?Arrow

While taking Sacusafe 50mg Tablet, it's generally advised to maintain a consistent salt intake and avoid excessive potassium intake, as this medication can affect potassium levels. Consult your doctor or a registered dietitian for personalized dietary advice.

Can I drink alcohol while taking Sacusafe 50mg Tablet?Arrow

It's generally recommended to avoid or limit alcohol consumption while taking Sacusafe 50mg Tablet, as alcohol can increase the risk of side effects such as dizziness and low blood pressure. Consult your doctor for personalized advice.

How long does it take for Sacusafe 50mg Tablet to show its effects?Arrow

The time it takes for Sacusafe 50mg Tablet to show its effects can vary among individuals. Some patients may experience improvement in their symptoms within a few weeks, while others may take longer. It's important to continue taking the medication as prescribed by your doctor for the best results.

What should I do if I overdose on Sacusafe 50mg Tablet?Arrow

If you suspect an overdose of Sacusafe 50mg Tablet, seek immediate medical attention. Symptoms of an overdose may include severe dizziness, fainting, and irregular heartbeat.

Can Sacusafe 50mg Tablet be used in patients with diabetes?Arrow

Sacusafe 50mg Tablet can be used in patients with diabetes, but it is important to monitor blood sugar levels regularly, as this medication may affect glucose metabolism. Consult your doctor for appropriate monitoring and management.

References

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FDA label for Entresto (sacubitril/valsartan). Contains information about sacubitril, one of the active ingredients in SACUSAFE.

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European Medicines Agency (EMA) assessment report for Entresto. Provides detailed scientific information about the drug.

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Packer M. Sacubitril/valsartan: a new approach to the treatment of heart failure. Clinical Pharmacology & Therapeutics. 2016 Sep;100(3):251-260. A research article on the effects of Sacubitril/valsartan.

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Yancy CW, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;128:e240-e327. Heart Failure Guidelines which may reference use of sacubitril/valsartan.

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