SAMLOKIND AT TABLET 10'S

How SAMLOKIND AT TABLET 10'S Works

• SAMLOKIND AT TABLET 10'S is a combination medication designed to manage hypertension (high blood pressure) and reduce the risk of cardiovascular events. It combines two active ingredients: Amlodipine and Atenolol. Each component works through a different mechanism of action to achieve a synergistic effect in lowering blood pressure.
• Amlodipine is a calcium channel blocker. It primarily works by relaxing and widening the blood vessels, which allows blood to flow more easily. Specifically, Amlodipine blocks the influx of calcium ions into vascular smooth muscle cells and cardiac muscle cells. In vascular smooth muscle, this reduction in calcium influx inhibits the contraction of these cells, causing vasodilation (widening of blood vessels). By dilating the arteries, Amlodipine reduces the total peripheral resistance, which is the resistance the heart has to pump against. This leads to a decrease in blood pressure. Amlodipine's effect is more pronounced in arterioles (small arteries) than in veins.
• Atenolol, on the other hand, is a beta-blocker. It works by selectively blocking beta-1 adrenergic receptors, which are primarily found in the heart. By blocking these receptors, Atenolol reduces the effects of adrenaline (epinephrine) and noradrenaline (norepinephrine) on the heart. This results in several key effects: a decrease in heart rate, a decrease in the force of heart muscle contraction (contractility), and a slowing of the conduction of electrical impulses through the heart. All these actions lead to a reduction in cardiac output, which is the amount of blood the heart pumps per minute. By reducing cardiac output, Atenolol helps to lower blood pressure.
• The combination of Amlodipine and Atenolol provides a more comprehensive approach to managing hypertension compared to using either medication alone. Amlodipine reduces peripheral resistance, while Atenolol reduces cardiac output. This dual action effectively lowers blood pressure and reduces the workload on the heart. This combination is particularly useful for individuals who require more than one medication to control their blood pressure or those who benefit from the complementary mechanisms of action.
• SAMLOKIND AT is typically prescribed for patients with hypertension, angina (chest pain), and certain other heart conditions. By lowering blood pressure, the medication helps to reduce the risk of serious cardiovascular complications such as stroke, heart attack, and kidney problems. The regular use of SAMLOKIND AT, as prescribed by a healthcare professional, plays a crucial role in managing blood pressure and promoting long-term cardiovascular health. It is important to take the medication as directed and to maintain regular check-ups with your doctor to monitor its effectiveness and manage any potential side effects.

Common side effects of Samlokind AT Tablet may include nausea, vomiting, diarrhea, stomach pain, heartburn, loss of appetite, dry mouth, headache, dizziness, drowsiness, fatigue, skin rash, itching, and increased liver enzymes. Less common but potentially serious side effects include allergic reactions (such as swelling of the face, lips, tongue, or throat; difficulty breathing), mood changes, depression, suicidal thoughts, muscle pain or weakness, numbness or tingling, and vision changes. Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of Samlokind AT Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep SAMLOKIND AT TAB 1X10 away from the reach of children and pets.
• Store SAMLOKIND AT TAB 1X10 at room temperature.

• **Take as Directed:** Always take SAMLOKIND AT TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them first. Adhering to the prescribed regimen optimizes the medication's effectiveness in managing your blood pressure and chest pain.
• **Consistency is Key:** For best results, take SAMLOKIND AT TABLET 10'S at the same time each day. This helps maintain a steady level of the medication in your bloodstream, providing consistent control over your symptoms. Setting a daily reminder can be a helpful strategy.
• **Monitor Your Blood Pressure:** Regularly monitor your blood pressure as directed by your healthcare provider. Keeping a log of your readings will help your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Note that SAMLOKIND AT TABLET 10'S takes time to show its full effect.
• **Lifestyle Modifications:** Support the effectiveness of SAMLOKIND AT TABLET 10'S with healthy lifestyle choices. This includes maintaining a balanced diet low in sodium and saturated fats, engaging in regular physical activity (as approved by your doctor), and avoiding smoking and excessive alcohol consumption. These changes can significantly contribute to overall cardiovascular health.
• **Potential Side Effects:** Be aware of potential side effects such as dizziness, lightheadedness, or swelling in your ankles or feet. If you experience any bothersome or persistent side effects, promptly inform your doctor. They can provide guidance on managing these effects or adjust your medication if needed. Do not stop taking the medication without consulting your doctor.

• SAMLOKIND AT TABLET 10'S can be taken with or without food. There are no specific food restrictions while taking this medication. However, it is advisable to avoid excessive consumption of grapefruit juice, as it might interact with the absorption of some ingredients in the medicine.