SEROFLO 125
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SEROFLO 125
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SEROFLO 125 SYNCHRO 120 MD

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SEROFLO 125 SYNCHRO 120 MD

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

819.89

₹696.91

15 % OFF

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Product DetailsArrow

About SEROFLO 125 SYNCHRO 120 MD

  • SEROFLO 125 SYNCHRO 120 MD is a combination medication meticulously formulated to manage and prevent respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients: Fluticasone propionate and Salmeterol.
  • Fluticasone propionate is a corticosteroid that reduces inflammation in the airways. By suppressing the release of inflammatory substances, it helps to decrease swelling and mucus production in the lungs, making breathing easier. This ingredient is crucial for long-term control of asthma symptoms.
  • Salmeterol is a long-acting beta-agonist (LABA) that works by relaxing the muscles around the airways, causing them to widen. This bronchodilation effect helps to relieve symptoms such as wheezing, shortness of breath, and chest tightness. The effects of salmeterol can last for up to 12 hours, providing prolonged relief.
  • The Synchro-Breathe technology ensures consistent and reliable drug delivery with each inhalation, optimizing the therapeutic effect. This metered-dose inhaler (MDI) is designed for ease of use, allowing patients to effectively manage their respiratory symptoms. SEROFLO 125 SYNCHRO 120 MD should be used regularly as prescribed by your doctor, even if you feel well, to maintain optimal control of your condition. It is not intended to relieve sudden symptoms of breathlessness; a fast-acting inhaler should be used for that purpose.
  • Always follow your doctor's instructions regarding dosage and administration. Common side effects may include throat irritation, hoarseness, and oral thrush. Rinse your mouth with water after each use to minimize the risk of these side effects. If you experience any severe side effects or allergic reactions, seek immediate medical attention.
  • SEROFLO 125 SYNCHRO 120 MD offers a convenient and effective way to manage asthma and COPD, helping patients to breathe easier and improve their quality of life. Regular use, as directed, can significantly reduce the frequency and severity of respiratory symptoms.

Uses of SEROFLO 125 SYNCHRO 120 MD

  • Relief from asthma symptoms
  • Management of Chronic Obstructive Pulmonary Disease (COPD)
  • Prevention of breathing difficulties
  • Reduction in wheezing and shortness of breath
  • Reducing airway inflammation
  • Improvement in lung function
  • Prevention of exercise-induced asthma

How SEROFLO 125 SYNCHRO 120 MD Works

  • SEROFLO 125 SYNCHRO 120 MD is a combination medication designed to manage and prevent symptoms associated with asthma and chronic obstructive pulmonary disease (COPD). It contains two active ingredients: Fluticasone Propionate and Salmeterol.
  • Fluticasone Propionate is a corticosteroid. It works by reducing inflammation in the airways. When inhaled, it suppresses the release of inflammatory substances, such as cytokines and chemokines, which contribute to airway swelling and mucus production. By reducing inflammation, fluticasone helps to open up the airways, making it easier to breathe and reducing the frequency of asthma attacks or COPD exacerbations. It essentially calms down the hyperreactive airways, preventing them from overreacting to triggers like allergens or irritants.
  • Salmeterol is a long-acting beta2-adrenergic agonist (LABA). It works by relaxing the smooth muscles surrounding the airways. When inhaled, salmeterol binds to beta2 receptors in the lungs, stimulating the production of cyclic AMP (cAMP). Increased cAMP levels cause the smooth muscles to relax, leading to bronchodilation, or widening of the airways. This bronchodilation effect provides relief from symptoms such as wheezing, shortness of breath, and chest tightness. The effects of salmeterol last for about 12 hours, providing sustained relief and preventing bronchospasm.
  • When used together, fluticasone and salmeterol provide complementary benefits. Fluticasone reduces inflammation, addressing the underlying cause of airway hyperreactivity, while salmeterol provides immediate and long-lasting bronchodilation to relieve symptoms. This combination helps to control both the inflammatory and bronchoconstriction components of asthma and COPD, leading to improved lung function, reduced symptoms, and a better quality of life for individuals with these conditions. The 'SYNCHRO' technology in the inhaler ensures consistent and reliable delivery of the medication with each dose, and 'MD' likely refers to a metered-dose inhaler.
  • In summary, SEROFLO 125 SYNCHRO 120 MD works by reducing inflammation in the airways with Fluticasone and relaxing the airway muscles with Salmeterol, making it easier to breathe and preventing symptoms associated with asthma and COPD.

Side Effects of SEROFLO 125 SYNCHRO 120 MDArrow

Like all medicines, SEROFLO 125 SYNCHRO 120 MD can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Sore throat * Hoarseness/Voice changes * Oral thrush (a fungal infection in the mouth) - can be reduced by rinsing your mouth with water after each use * Headache * Muscle cramps * Joint pain **Uncommon Side Effects (may affect up to 1 in 100 people):** * Feeling anxious * Sleeping problems * Restlessness * Cough * Dry mouth * Skin rash * Shaking * Fast heart rate * Heart palpitations **Rare Side Effects (may affect up to 1 in 1,000 people):** * Worsening of breathing difficulties immediately after taking the medicine. * Wheezing * Chest tightness **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Difficulty in breathing * Allergic reactions such as skin rash, itching, swelling of the face, mouth and throat * Anxiety * Depression * Changes in blood sugar levels * Glaucoma * Cataracts * Disturbed sleep * Irregular heart beat **Frequency not known:** * Paradoxical bronchospasm (unexpected tightening of the airways) * Problems with your eyes such as blurred vision This is not a complete list. Consult your doctor or pharmacist for a full list and if you experience any other unusual symptoms.

Safety Advice for SEROFLO 125 SYNCHRO 120 MDArrow

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Allergies

Caution

Use caution if you are allergic to this medicine.

Dosage of SEROFLO 125 SYNCHRO 120 MDArrow

  • The recommended dosage of SEROFLO 125 SYNCHRO 120 MD is individualized and depends on the severity of your condition, your response to treatment, and any other medications you may be taking. It is crucial to adhere strictly to your doctor's prescribed dosage and administration schedule.
  • Typically, SEROFLO 125 SYNCHRO 120 MD is administered via inhalation using a suitable inhaler device. Your doctor or a trained healthcare professional will demonstrate the correct inhalation technique to ensure optimal drug delivery to your lungs. This usually involves exhaling completely, placing the inhaler mouthpiece in your mouth, and inhaling deeply and steadily while simultaneously actuating the inhaler to release the medication. Hold your breath for as long as comfortable (usually 5-10 seconds) to allow the medication to deposit in your airways before exhaling slowly.
  • The usual starting dosage for adults and adolescents may be one or two inhalations twice daily, approximately 12 hours apart. In some cases, your doctor may initially prescribe a higher dose to rapidly control symptoms, followed by a gradual reduction to the lowest effective maintenance dose. The maximum daily dose should not exceed the number of inhalations recommended by your physician.
  • For children, the dosage is generally lower and carefully adjusted based on their weight, age, and the severity of their asthma or COPD. Always use a spacer device with young children to improve medication delivery and reduce the risk of side effects.
  • It is important to use SEROFLO 125 SYNCHRO 120 MD regularly, even if you are feeling well, to maintain control of your respiratory symptoms. Do not stop using SEROFLO 125 SYNCHRO 120 MD abruptly without consulting your doctor, as this may lead to a worsening of your condition.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Rinse your mouth with water after each use of SEROFLO 125 SYNCHRO 120 MD to help prevent oral thrush (a fungal infection in the mouth).
  • Take 'SEROFLO 125 SYNCHRO 120 MD' only as per the prescription by your physician only

What if I miss my dose of SEROFLO 125 SYNCHRO 120 MD?Arrow

  • If you miss a dose of SEROFLO 125 SYNCHRO 120 MD, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store SEROFLO 125 SYNCHRO 120 MD?Arrow

  • Keep SEROFLO 125 SYNCHRO 120MD away from the reach of children and pets.
  • Store SEROFLO 125 SYNCHRO 120MD at room temperature.

Benefits of SEROFLO 125 SYNCHRO 120 MDArrow

  • SEROFLO 125 SYNCHRO 120 MD offers a comprehensive approach to managing chronic respiratory conditions, primarily asthma and Chronic Obstructive Pulmonary Disease (COPD). Its dual-action formulation provides both bronchodilation and anti-inflammatory effects, leading to significant improvements in breathing and overall quality of life. The primary benefit lies in its ability to effectively control and prevent symptoms such as wheezing, shortness of breath, chest tightness, and coughing. By relaxing the muscles in the airways, SEROFLO 125 SYNCHRO 120 MD facilitates easier airflow, making it easier to breathe, particularly during periods of exacerbation or increased physical activity.
  • The anti-inflammatory component of SEROFLO 125 SYNCHRO 120 MD works to reduce swelling and irritation in the airways. This helps to minimize long-term damage to the lungs and reduce the frequency and severity of asthma attacks or COPD flare-ups. Regular use of SEROFLO 125 SYNCHRO 120 MD, as prescribed by a healthcare professional, can lead to a significant reduction in the need for rescue medication, such as short-acting bronchodilators, providing greater stability and control over respiratory symptoms.
  • Furthermore, SEROFLO 125 SYNCHRO 120 MD helps improve lung function over time. Consistent use, coupled with proper inhaler technique, allows for better oxygen exchange in the lungs, leading to increased energy levels and improved physical endurance. Patients often find they can engage in daily activities with greater ease and experience fewer limitations due to their respiratory condition.
  • SEROFLO 125 SYNCHRO 120 MD's convenient dry powder inhaler (DPI) formulation simplifies administration. The SYNCHRO 120 MD device is designed for ease of use, ensuring that patients can effectively deliver the medication directly to their lungs with minimal effort. This ease of use is particularly beneficial for elderly patients or those with limited dexterity. Its compact and portable design allows for convenient use at home or on the go, empowering individuals to manage their respiratory health proactively, no matter where they are.
  • Finally, SEROFLO 125 SYNCHRO 120 MD can significantly improve sleep quality for those with nocturnal asthma or COPD symptoms. By keeping airways open and reducing coughing or wheezing during the night, it promotes more restful and undisturbed sleep. This, in turn, contributes to improved daytime alertness, mood, and overall well-being. The combined benefits of symptom control, improved lung function, ease of use, and enhanced sleep quality make SEROFLO 125 SYNCHRO 120 MD a valuable tool in the management of chronic respiratory diseases, helping patients live fuller, more active lives.

How to use SEROFLO 125 SYNCHRO 120 MDArrow

  • SEROFLO 125 SYNCHRO 120 MD is a combination medicine containing fluticasone propionate and salmeterol. It is crucial to use this inhaler exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting your healthcare provider.
  • Before using SEROFLO 125 SYNCHRO 120 MD for the first time, or if it hasn't been used for a week or more, prime the inhaler. To prime, remove the cap and shake the inhaler well. Then, press down on the canister to release a spray into the air. Repeat this process four times. Make sure to keep the inhaler clean and dry. Replace the cap immediately after use.
  • To use the inhaler, first, shake it well. Then, remove the cap and breathe out fully, away from the inhaler. Place the mouthpiece between your teeth and close your lips around it. Start to breathe in slowly and deeply through your mouth. As you breathe in, press down firmly on the canister to release a puff of medicine. Continue to inhale deeply and slowly.
  • Remove the inhaler from your mouth and hold your breath for about 10 seconds, or as long as is comfortable. Then, breathe out slowly. If your doctor has prescribed more than one puff, wait about 30 seconds and repeat the steps. Rinse your mouth with water after each use, and spit the water out. This helps to prevent thrush (a fungal infection) in your mouth and throat.
  • It is vital to clean your SEROFLO 125 SYNCHRO 120 MD inhaler regularly. Remove the canister and wash the plastic actuator with warm water. Allow it to air dry completely before reassembling. Never immerse the canister in water. Store SEROFLO 125 SYNCHRO 120 MD at room temperature, away from direct heat and sunlight. Keep it out of reach of children.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. Always consult your doctor or pharmacist if you have any questions or concerns about using SEROFLO 125 SYNCHRO 120 MD.
  • Regularly check with your doctor about how your medication is working for you. This is important to monitor your condition and make sure you're getting the maximum benefit from SEROFLO 125 SYNCHRO 120 MD.

Quick Tips for SEROFLO 125 SYNCHRO 120 MDArrow

  • **Consistency is Key:** Use SEROFLO 125 SYNCHRO 120 MD every day, even if you feel well. This helps maintain consistent control of your asthma or COPD symptoms. Skipping doses can lead to a flare-up.
  • **Proper Inhalation Technique:** Ensure you're using the inhaler correctly. Breathe out fully before placing the inhaler in your mouth, then inhale deeply and slowly while pressing down on the canister. Hold your breath for 10 seconds to allow the medication to reach your lungs.
  • **Rinse Your Mouth After Use:** After each use, rinse your mouth thoroughly with water and spit it out. This helps prevent oral thrush (a fungal infection) and reduces the risk of hoarseness.
  • **Clean Your Inhaler Regularly:** Keep your inhaler clean by wiping the mouthpiece with a dry cloth regularly. Do not wash or immerse the inhaler in water, as this can damage the device.
  • **Monitor Your Symptoms:** Keep a record of your symptoms and any changes you experience while using SEROFLO 125 SYNCHRO 120 MD. Share this information with your doctor during your regular check-ups to ensure optimal management of your condition.
  • **Avoid Triggers:** Identify and avoid triggers that worsen your asthma or COPD symptoms, such as smoke, pollen, dust, and strong odors. Maintaining a healthy lifestyle, including regular exercise and a balanced diet, can also help manage your condition effectively.
  • **Know When to Seek Help:** If you experience worsening shortness of breath, chest pain, or other severe symptoms, seek immediate medical attention. Do not rely solely on SEROFLO 125 SYNCHRO 120 MD for acute relief of sudden symptoms.

Food Interactions with SEROFLO 125 SYNCHRO 120 MDArrow

  • SEROFLO 125 SYNCHRO 120 MD does not have any known significant interactions with food. It can be taken with or without food. However, it is always recommended to follow your doctor's instructions regarding dosage and timing of administration for optimal results.
  • Avoid consuming large amounts of caffeine (e.g., coffee, tea, chocolate) as it may increase the risk of side effects such as nervousness, tremor, or palpitations.

FAQs

What is Sereflo 125 Synchro 120 MD used for?Arrow

Sereflo 125 Synchro 120 MD is primarily used to manage and prevent symptoms of asthma and chronic obstructive pulmonary disease (COPD). It helps to relieve wheezing, shortness of breath, chest tightness, and coughing.

What are the main ingredients in Sereflo 125 Synchro 120 MD?Arrow

Sereflo 125 Synchro 120 MD contains two active ingredients: Fluticasone Propionate (an inhaled corticosteroid) and Salmeterol (a long-acting beta-agonist or LABA).

How should I use Sereflo 125 Synchro 120 MD?Arrow

Use Sereflo 125 Synchro 120 MD as prescribed by your doctor. Typically, it's administered using an inhaler. Follow the instructions provided with the inhaler device and ensure you clean it regularly.

What are the possible side effects of Sereflo 125 Synchro 120 MD?Arrow

Possible side effects include sore throat, hoarseness, upper respiratory tract infection, headache, muscle cramps, and palpitations. Consult your doctor if you experience severe or persistent side effects.

Can I use Sereflo 125 Synchro 120 MD during pregnancy?Arrow

If you are pregnant or planning to become pregnant, consult your doctor before using Sereflo 125 Synchro 120 MD. They will assess the potential risks and benefits for you and your baby.

How should Sereflo 125 Synchro 120 MD be stored?Arrow

Store Sereflo 125 Synchro 120 MD at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

What should I do if I miss a dose of Sereflo 125 Synchro 120 MD?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Can I use Sereflo 125 Synchro 120 MD with other medications?Arrow

Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, before starting Sereflo 125 Synchro 120 MD.

Is Sereflo 125 Synchro 120 MD a rescue inhaler?Arrow

No, Sereflo 125 Synchro 120 MD is not a rescue inhaler. It is a maintenance medication used to prevent symptoms. Use a rescue inhaler (like albuterol) for sudden breathing difficulties.

How long does it take for Sereflo 125 Synchro 120 MD to start working?Arrow

The effects of Sereflo 125 Synchro 120 MD are not immediate. It may take several days to weeks of regular use to experience the full benefits. Continue using it as prescribed, even if you feel better.

What should I do if I accidentally overdose on Sereflo 125 Synchro 120 MD?Arrow

Seek immediate medical attention if you suspect an overdose. Symptoms may include rapid heartbeat, tremors, chest pain, and seizures.

Can Sereflo 125 Synchro 120 MD cause thrush?Arrow

Yes, inhaled corticosteroids like fluticasone in Sereflo can sometimes cause oral thrush (a fungal infection in the mouth). Rinse your mouth with water after each use to help prevent this.

Is there a generic alternative to Sereflo 125 Synchro 120 MD?Arrow

Yes, there are generic alternatives containing fluticasone and salmeterol available. Discuss with your doctor or pharmacist to see if a generic option is suitable for you.

Can Sereflo 125 Synchro 120 MD affect my growth if I use it long-term?Arrow

Long-term use of inhaled corticosteroids like fluticasone may potentially affect growth in children. Your doctor will monitor growth regularly if your child is on this medication for an extended period.

What should I do if Sereflo 125 Synchro 120 MD does not seem to be working?Arrow

If you feel that Sereflo 125 Synchro 120 MD is not effectively controlling your symptoms, consult your doctor. They may need to adjust your dosage or explore alternative treatment options.

References

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Seretide Accuhaler (fluticasone propionate / salmeterol). European Medicines Agency. EPAR - Product Information.

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ADVAIR DISKUS (fluticasone propionate and salmeterol inhalation powder). US Food and Drug Administration. Label.

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Effectiveness of salmeterol/fluticasone combination therapy in COPD patients with frequent exacerbations: A real-world study. International Journal of COPD.

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Fluticasone furoate/salmeterol combination therapy for asthma. Expert Review of Respiratory Medicine.

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Fluticasone propionate. DrugBank.

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Salmeterol. DrugBank.

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