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SIAGLIDE M OD 100/1000MG TABLET 15'S
SIAGLIDE M OD 100/1000MG TABLET 15'S
By ABBOTT HEALTH CARE PRIVATE LIMITED
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Product Details
About SIAGLIDE M OD 100/1000MG TABLET 15'S
- SIAGLIDE M OD 100/1000MG TABLET is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients: Sitagliptin and Metformin Hydrochloride. This medication is typically prescribed when diet and exercise alone are not sufficient to control blood glucose.
- Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by increasing the amount of incretin hormones released by the intestine. These hormones help to increase insulin release after a meal and decrease the amount of glucose produced by the liver. By enhancing the action of incretin hormones, sitagliptin helps to regulate blood sugar levels.
- Metformin Hydrochloride is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It also helps to reduce the amount of glucose absorbed from the intestines. Metformin is a commonly used first-line treatment for type 2 diabetes due to its effectiveness and relatively low risk of causing hypoglycemia (low blood sugar) when used alone.
- The 'OD' in SIAGLIDE M OD stands for 'Once Daily,' indicating that this formulation is designed to be taken once a day, offering convenience for patients. The 100/1000MG designation refers to the strength of each tablet, with 100mg of Sitagliptin and 1000mg of Metformin Hydrochloride.
- This medication is usually taken with meals to minimize gastrointestinal side effects. Common side effects may include nausea, vomiting, diarrhea, and abdominal discomfort. It's important to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly while taking SIAGLIDE M OD 100/1000MG TABLET. Patients with kidney problems should use this medicine with caution and after consulting with the doctor.
- SIAGLIDE M OD 100/1000MG TABLET is a prescription medication, and it is essential to consult with a healthcare professional to determine if it is appropriate for your individual needs and medical condition. They can provide guidance on dosage, potential side effects, and interactions with other medications you may be taking.
Uses of SIAGLIDE M OD 100/1000MG TABLET 15'S
- Treatment of type 2 diabetes mellitus
- Control high blood sugar levels
- Used in conjunction with diet and exercise
- Improve insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)
How SIAGLIDE M OD 100/1000MG TABLET 15'S Works
- SIAGLIDE M OD 100/1000MG TABLET 15'S is a combination medicine designed to manage type 2 diabetes mellitus. It combines two active ingredients: Sitagliptin and Metformin. Each component works through different mechanisms to achieve better blood sugar control.
- Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 enzymes break down incretin hormones. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are naturally produced by the body and play a crucial role in regulating blood sugar levels, especially after meals. They stimulate insulin release from the pancreas when blood sugar is high and reduce glucagon secretion from the liver, which lowers glucose production. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body, leading to improved insulin secretion and reduced glucagon levels, ultimately helping to lower blood sugar levels after meals and throughout the day.
- Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver produces glucose from non-carbohydrate sources. Metformin also improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines after a meal. Unlike some other diabetes medications, Metformin does not typically cause hypoglycemia (low blood sugar) when used alone.
- The combination of Sitagliptin and Metformin in SIAGLIDE M OD 100/1000MG TABLET 15'S provides a dual approach to managing blood sugar levels. Sitagliptin enhances insulin secretion and reduces glucagon, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic effect helps to achieve better glycemic control than either medication could achieve alone. The OD (Once Daily) formulation provides a sustained release of the medication, ensuring a consistent effect throughout the day. It is crucial to take SIAGLIDE M OD 100/1000MG TABLET 15'S as prescribed by your doctor, usually with a meal, to minimize potential gastrointestinal side effects and maximize its effectiveness in managing your blood sugar levels. Regular monitoring of blood sugar and adherence to a healthy diet and exercise plan are also essential for optimal diabetes management.
Side Effects of SIAGLIDE M OD 100/1000MG TABLET 15'S
Possible side effects of SIAGLIDE M OD 100/1000MG TABLET may include: Common side effects: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste. Uncommon side effects: Hypoglycemia (low blood sugar), Headache, Dizziness, Weakness, Fatigue, Rash, Itching, Urticaria. Rare side effects: Lactic acidosis, Vitamin B12 deficiency, Liver problems, Allergic reactions (e.g., angioedema, anaphylaxis). Other side effects: Constipation, Flatulence. This is not an exhaustive list, and individual reactions may vary. Consult your doctor if you experience any persistent or severe side effects.
Safety Advice for SIAGLIDE M OD 100/1000MG TABLET 15'S
Allergies
UnsafeDo not use this medicine if you are allergic to it.
Dosage of SIAGLIDE M OD 100/1000MG TABLET 15'S
- The recommended dosage of 'SIAGLIDE M OD 100/1000MG TABLET 15'S' varies depending on individual patient needs, blood glucose levels, and other medications being taken. It's crucial to adhere strictly to your doctor's instructions. Typically, the starting dose is one tablet daily, usually taken with the morning meal to minimize gastrointestinal side effects. Your physician may adjust the dosage gradually based on your glycemic response and tolerance. The maximum daily dose should not exceed the recommended limit as specified by your healthcare provider.
- Consistency in timing and adherence to dietary recommendations are crucial for optimal results. It is generally recommended to take 'SIAGLIDE M OD 100/1000MG TABLET 15'S' at the same time each day to maintain stable blood glucose levels. If you miss a dose, do not double up on the next dose. Instead, take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
- Regular monitoring of blood glucose levels is essential while taking 'SIAGLIDE M OD 100/1000MG TABLET 15'S' to assess the effectiveness of the medication and to guide dosage adjustments. It's important to inform your doctor about any other medications, supplements, or herbal remedies you are taking, as they may interact with 'SIAGLIDE M OD 100/1000MG TABLET 15'S'. Certain medical conditions, such as kidney or liver problems, may also affect the dosage. Always consult your physician for personalized advice regarding the appropriate dosage for your specific situation. Take 'SIAGLIDE M OD 100/1000MG TABLET 15'S' only as per the prescription by your physician only.
What if I miss my dose of SIAGLIDE M OD 100/1000MG TABLET 15'S?
- If you miss a dose of SIAGLIDE M OD 100/1000MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
How to store SIAGLIDE M OD 100/1000MG TABLET 15'S?
- Keep SIAGLIDE M OD 100/1000MG TAB 1X15 away from the reach of children and pets.
- Store SIAGLIDE M OD 100/1000MG TAB 1X15 at room temperature.
Benefits of SIAGLIDE M OD 100/1000MG TABLET 15'S
- SIAGLIDE M OD 100/1000MG TABLET 15'S is a combination medication designed to effectively manage type 2 diabetes mellitus. It combines two powerful active ingredients, Sitagliptin and Metformin, to provide comprehensive glycemic control. This medication works through complementary mechanisms to lower blood sugar levels and improve overall metabolic health.
- Sitagliptin, a DPP-4 inhibitor, enhances the body's natural ability to lower blood sugar. It works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which breaks down incretin hormones. Incretin hormones, such as GLP-1 and GIP, stimulate insulin release from the pancreas and reduce glucagon secretion from the liver. By increasing the levels of active incretin hormones, Sitagliptin helps to increase insulin secretion when blood sugar is high and decrease glucagon secretion, thereby reducing glucose production by the liver. This action is glucose-dependent, meaning it primarily works when blood sugar levels are elevated, reducing the risk of hypoglycemia.
- Metformin, a biguanide, primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces hepatic glucose output by suppressing gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin increases insulin sensitivity in peripheral tissues, such as muscle, allowing cells to utilize glucose more effectively. It also slows down the absorption of glucose from the intestines, further contributing to lower post-meal blood sugar spikes.
- The combination of Sitagliptin and Metformin in SIAGLIDE M OD offers several key benefits for individuals with type 2 diabetes. Firstly, it provides dual action in controlling blood sugar levels, targeting both insulin secretion and insulin sensitivity. This synergistic effect often results in better glycemic control compared to using either medication alone. Secondly, the once-daily (OD) formulation enhances convenience and adherence, making it easier for patients to manage their medication regimen. Improved adherence can lead to better long-term outcomes in diabetes management.
- SIAGLIDE M OD helps to lower HbA1c levels, a measure of average blood sugar control over the past 2-3 months. By effectively managing blood sugar, it reduces the risk of long-term complications associated with diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). Maintaining stable blood sugar levels also helps to improve energy levels, reduce fatigue, and enhance overall quality of life for individuals with diabetes.
- Furthermore, SIAGLIDE M OD may offer weight management benefits. Metformin, in particular, has been shown to have a modest weight-lowering effect in some individuals. Unlike some other diabetes medications, Sitagliptin is generally weight-neutral, meaning it does not typically cause weight gain. This can be particularly beneficial for individuals with type 2 diabetes who are also trying to manage their weight.
- In summary, SIAGLIDE M OD 100/1000MG TABLET 15'S is a valuable medication for managing type 2 diabetes. Its dual mechanism of action, convenient once-daily dosing, and potential weight management benefits make it an effective option for improving glycemic control and reducing the risk of diabetes-related complications. Always use under medical supervision.
How to use SIAGLIDE M OD 100/1000MG TABLET 15'S
- SIAGLIDE M OD 100/1000MG Tablet is designed for oral administration and should be taken as prescribed by your doctor. The 'OD' in the name signifies 'Once Daily,' indicating that it's usually taken once a day. Always follow your doctor's specific instructions regarding dosage and timing, as they may adjust it based on your individual needs and response to the medication.
- It is generally recommended to take SIAGLIDE M OD with food, preferably with your first main meal of the day (usually breakfast). This helps to reduce the likelihood of stomach upset and also aids in the absorption of the medication. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system.
- Consistency is key for optimal results. Try to take SIAGLIDE M OD at the same time each day. This helps to maintain a steady level of the medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
- SIAGLIDE M OD works best when combined with a healthy lifestyle. This includes following a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. Your doctor may also recommend monitoring your blood sugar levels regularly to track your progress and ensure the medication is working effectively. Discuss any changes to your diet or exercise routine with your doctor, as these can affect your blood sugar levels and the effectiveness of SIAGLIDE M OD.
- It is important to inform your doctor about all other medications, supplements, or herbal remedies you are taking, as some can interact with SIAGLIDE M OD. Pay attention to any side effects you may experience, and report them to your doctor promptly. Common side effects may include nausea, diarrhea, or headache. Regular follow-up appointments with your doctor are crucial for monitoring your condition and adjusting your treatment plan as needed. Never stop taking SIAGLIDE M OD without consulting your doctor, even if you feel better, as this could lead to a worsening of your condition.
Quick Tips for SIAGLIDE M OD 100/1000MG TABLET 15'S
- Take SIAGLIDE M OD 100/1000MG TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or discontinue the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen optimizes blood sugar control and minimizes potential side effects.
- It is recommended to take SIAGLIDE M OD 100/1000MG TABLET 15'S with food, preferably with your first main meal of the day. This helps to reduce the likelihood of gastrointestinal side effects such as nausea, vomiting, or diarrhea, which are sometimes associated with metformin, one of the active ingredients.
- Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. Keeping a log of your blood glucose readings will help you and your healthcare team assess how well SIAGLIDE M OD 100/1000MG TABLET 15'S is working for you and make any necessary adjustments to your treatment plan. Discuss these readings during your regular check-ups.
- Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking. Certain medications can interact with SIAGLIDE M OD 100/1000MG TABLET 15'S, potentially affecting its efficacy or increasing the risk of adverse effects. This includes over-the-counter drugs as well.
- Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. SIAGLIDE M OD 100/1000MG TABLET 15'S works best when combined with lifestyle modifications. Consult a registered dietitian or certified diabetes educator for personalized meal planning and exercise recommendations. Also, stay hydrated by drinking plenty of water throughout the day.
- Be aware of the symptoms of hypoglycemia (low blood sugar) such as shakiness, sweating, confusion, and dizziness. Always carry a source of fast-acting sugar, such as glucose tablets or fruit juice, to treat hypoglycemia promptly. Inform your family and friends about how to recognize and treat hypoglycemia in case you are unable to do so yourself.
- If you are scheduled for any surgery or medical procedure, including dental work, inform your doctor or surgeon that you are taking SIAGLIDE M OD 100/1000MG TABLET 15'S. It may be necessary to temporarily discontinue the medication before the procedure to minimize the risk of complications.
- Store SIAGLIDE M OD 100/1000MG TABLET 15'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not store the medication in the bathroom.
- Attend all scheduled appointments with your doctor and other healthcare providers. These visits are essential for monitoring your progress, adjusting your treatment plan as needed, and addressing any concerns or questions you may have about your diabetes management.
- If you experience any persistent or bothersome side effects while taking SIAGLIDE M OD 100/1000MG TABLET 15'S, such as severe gastrointestinal upset or signs of an allergic reaction, contact your doctor immediately. Do not attempt to self-treat or ignore these symptoms.
Food Interactions with SIAGLIDE M OD 100/1000MG TABLET 15'S
- SIAGLIDE M OD 100/1000MG TABLET 15'S should be taken with food to decrease the possibility of an upset stomach. Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis. Consult your doctor for specific dietary advice tailored to your health condition and other medications.
FAQs
What is the use of SIAGLIDE M OD 100/1000MG TABLET 15'S?
SIAGLIDE M OD 100/1000MG TABLET 15'S is used to treat type 2 diabetes mellitus, especially when diet and exercise alone are not enough to control blood sugar levels.
How does SIAGLIDE M OD 100/1000MG TABLET 15'S work?
SIAGLIDE M OD 100/1000MG TABLET 15'S is a combination of two medicines, Sitagliptin and Metformin. Sitagliptin works by increasing insulin secretion and decreasing glucagon levels, while Metformin reduces glucose production in the liver and increases insulin sensitivity.
What are the common side effects of SIAGLIDE M OD 100/1000MG TABLET 15'S?
Common side effects of SIAGLIDE M OD 100/1000MG TABLET 15'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.
Is SIAGLIDE M OD 100/1000MG TABLET 15'S safe for patients with kidney problems?
SIAGLIDE M OD 100/1000MG TABLET 15'S should be used with caution in patients with kidney problems, as Metformin is excreted by the kidneys. It is not recommended in patients with severe renal impairment.
How to store SIAGLIDE M OD 100/1000MG TABLET 15'S?
Store SIAGLIDE M OD 100/1000MG TABLET 15'S at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.
Should SIAGLIDE M OD 100/1000MG TABLET 15'S be taken with food?
It is recommended to take SIAGLIDE M OD 100/1000MG TABLET 15'S with food to minimize stomach upset.
What happens if I miss a dose of SIAGLIDE M OD 100/1000MG TABLET 15'S?
If you miss a dose of SIAGLIDE M OD 100/1000MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Is SIAGLIDE M OD 100/1000MG TABLET 15'S safe during pregnancy?
The safety of SIAGLIDE M OD 100/1000MG TABLET 15'S during pregnancy has not been established. It should be used only if the benefit outweighs the risk and as directed by a doctor.
What should I avoid while taking SIAGLIDE M OD 100/1000MG TABLET 15'S?
Avoid excessive alcohol consumption while taking SIAGLIDE M OD 100/1000MG TABLET 15'S, as it can lower blood sugar levels and increase the risk of lactic acidosis.
Can SIAGLIDE M OD 100/1000MG TABLET 15'S interact with other medications?
Yes, SIAGLIDE M OD 100/1000MG TABLET 15'S can interact with certain medications, such as insulin, sulfonylureas, and certain antihypertensive drugs. Inform your doctor about all your medications to avoid any potential interactions.
How should I monitor my blood sugar levels while taking SIAGLIDE M OD 100/1000MG TABLET 15'S?
Monitor your blood sugar levels regularly while taking SIAGLIDE M OD 100/1000MG TABLET 15'S, as directed by your doctor. You can use a home glucose meter.
Does SIAGLIDE M OD 100/1000MG TABLET 15'S cause weight gain?
SIAGLIDE M OD 100/1000MG TABLET 15'S does not typically cause weight gain. Metformin, one of the components of the medication, may actually cause weight loss in some individuals.
Can I exercise while taking SIAGLIDE M OD 100/1000MG TABLET 15'S?
Yes, it is important to exercise while taking SIAGLIDE M OD 100/1000MG TABLET 15'S, as it helps in controlling blood sugar levels and improving insulin sensitivity.
What is the difference between SIAGLIDE M OD 100/1000MG TABLET 15'S and other Metformin-containing medications?
SIAGLIDE M OD 100/1000MG TABLET 15'S is a combination of Metformin and Sitagliptin, while other medications may contain only Metformin or Metformin combined with another type of diabetes medication.
How long should I take SIAGLIDE M OD 100/1000MG TABLET 15'S?
The duration for which you should take SIAGLIDE M OD 100/1000MG TABLET 15'S will be determined by your doctor, depending on your blood sugar levels and overall health.
References
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Marketer / Manufacturer Details
ABBOTT HEALTH CARE PRIVATE LIMITED
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India
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