SIGLYN M 100/1000 TABLET 10'S

How SIGLYN M 100/1000 TABLET 10'S Works

• SIGLYN M 100/1000 Tablet is a combination medicine used to treat type 2 diabetes mellitus. It combines two antidiabetic medications: Sitagliptin and Metformin. This combination works through complementary mechanisms to control blood sugar levels effectively.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the amount of incretin hormones released by the gut after a meal. Incretin hormones help to stimulate insulin release from the pancreas and decrease the amount of glucagon (a hormone that raises blood sugar) produced by the liver. By increasing insulin and decreasing glucagon, sitagliptin helps lower blood sugar levels, particularly after meals.
• Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Specifically, metformin reduces hepatic glucose production by inhibiting gluconeogenesis (the process of creating glucose from non-carbohydrate sources). It also enhances insulin sensitivity in peripheral tissues (muscle and fat), allowing cells to better utilize available glucose. Furthermore, metformin slows down the absorption of glucose from the intestines into the bloodstream.
• The combination of sitagliptin and metformin provides a dual approach to managing blood sugar. Sitagliptin enhances insulin secretion and reduces glucagon, while metformin reduces glucose production and improves insulin sensitivity. This synergistic effect helps to achieve better glycemic control than either medication alone.
• SIGLYN M 100/1000 Tablet is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels in patients with type 2 diabetes. It's crucial to take this medication as directed by your doctor, usually with meals, to minimize gastrointestinal side effects associated with metformin. Regular monitoring of blood sugar levels and kidney function is also important while taking this medication.

Possible side effects of SIGLYN M 100/1000 Tablet may include: * **Common Side Effects:** Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Headache, Hypoglycemia (low blood sugar) – symptoms may include sweating, shakiness, anxiety, blurred vision, rapid heartbeat. * **Uncommon Side Effects:** Rash, Itching, Urticaria (hives), Vitamin B12 deficiency (symptoms may include fatigue, weakness, numbness or tingling in hands and feet, sore tongue), Lactic acidosis (rare but serious, symptoms include rapid breathing, stomach pain, feeling cold, irregular heartbeat), Altered taste, Constipation, Flatulence, Dizziness. * **Rare Side Effects:** Liver problems (symptoms may include yellowing of the skin or eyes, dark urine, abdominal pain), Allergic reactions (swelling of the face, lips, tongue, or throat, difficulty breathing).

• If you miss a dose of SIGLYN M 100/1000 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SIGLYN M 100/1000MG TAB 1X10 away from the reach of children and pets.
• Store SIGLYN M 100/1000MG TAB 1X10 at room temperature.

• Take SIGLYN M 100/1000 Tablet as prescribed by your doctor. It's crucial to follow the dosage and timing instructions to effectively manage your blood sugar levels. Consistency is key for optimal results. Do not alter the dosage without consulting your physician.
• SIGLYN M 100/1000 Tablet is typically taken with meals to minimize potential stomach upset and enhance absorption of the medication. Try to take it at the same time each day to maintain a steady level of the drug in your system, which will contribute to better glucose control throughout the day. Forgetting a dose can impact your glucose levels, so set up reminders if needed.
• Inform your doctor about all other medications, herbal supplements, and vitamins you are taking before starting SIGLYN M 100/1000 Tablet. Certain medications can interact with this drug, potentially altering its effectiveness or increasing the risk of side effects. Be especially mindful of informing your doctor about any heart or kidney issues you may have, as these conditions can influence the suitability of this medication.
• Monitor your blood sugar levels regularly, as directed by your healthcare provider, while taking SIGLYN M 100/1000 Tablet. Keeping a log of your readings can help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. It's also important to be aware of the signs and symptoms of both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar), and know how to respond to them.
• Maintain a healthy lifestyle while taking SIGLYN M 100/1000 Tablet. This includes eating a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. These lifestyle modifications can significantly improve your blood sugar control and reduce your risk of diabetes-related complications. Consider consulting with a registered dietitian or certified diabetes educator to develop a personalized meal plan and exercise regimen that suits your needs.

• SIGLYN M 100/1000 TABLET 10'S should be taken with food to decrease the possibility of an upset stomach.
• Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis.
• There are no specific foods to avoid unless otherwise directed by your doctor.